Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer
Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Akiyoshi, Takashi [verfasserIn] Matsueda, Kiyoshi [verfasserIn] Hiratsuka, Makiko [verfasserIn] Unno, Toshiyuki [verfasserIn] Nagata, Jun [verfasserIn] Nagasaki, Toshiya [verfasserIn] Konishi, Tsuyoshi [verfasserIn] Fujimoto, Yoshiya [verfasserIn] Nagayama, Satoshi [verfasserIn] Fukunaga, Yosuke [verfasserIn] Ueno, Masashi [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
Magnetic Resonance Imaging Finding |
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| Übergeordnetes Werk: |
Enthalten in: Annals of surgical oncology - Berlin [u.a.] : Springer, 1994, 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 |
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| Übergeordnetes Werk: |
volume:22 ; year:2015 ; number:Suppl 3 ; day:21 ; month:04 ; pages:614-620 |
| Links: |
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| DOI / URN: |
10.1245/s10434-015-4565-5 |
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| Katalog-ID: |
SPR009973605 |
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| 100 | 1 | |a Akiyoshi, Takashi |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer |
| 264 | 1 | |c 2015 | |
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| 520 | |a Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. | ||
| 650 | 4 | |a Total Mesorectal Excision |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Magnetic Resonance Imaging Finding |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pelvic Magnetic Resonance Imaging |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Lateral Pelvic Lymph Node |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Lateral Pelvic Lymph Node Dissection |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Matsueda, Kiyoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Hiratsuka, Makiko |e verfasserin |4 aut | |
| 700 | 1 | |a Unno, Toshiyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Nagata, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Nagasaki, Toshiya |e verfasserin |4 aut | |
| 700 | 1 | |a Konishi, Tsuyoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Fujimoto, Yoshiya |e verfasserin |4 aut | |
| 700 | 1 | |a Nagayama, Satoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Fukunaga, Yosuke |e verfasserin |4 aut | |
| 700 | 1 | |a Ueno, Masashi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Annals of surgical oncology |d Berlin [u.a.] : Springer, 1994 |g 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 |w (DE-627)343969947 |w (DE-600)2074021-9 |x 1534-4681 |7 nnns |
| 773 | 1 | 8 | |g volume:22 |g year:2015 |g number:Suppl 3 |g day:21 |g month:04 |g pages:614-620 |
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10.1245/s10434-015-4565-5 doi (DE-627)SPR009973605 (SPR)s10434-015-4565-5-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Akiyoshi, Takashi verfasserin aut Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. Total Mesorectal Excision (dpeaa)DE-He213 Magnetic Resonance Imaging Finding (dpeaa)DE-He213 Pelvic Magnetic Resonance Imaging (dpeaa)DE-He213 Lateral Pelvic Lymph Node (dpeaa)DE-He213 Lateral Pelvic Lymph Node Dissection (dpeaa)DE-He213 Matsueda, Kiyoshi verfasserin aut Hiratsuka, Makiko verfasserin aut Unno, Toshiyuki verfasserin aut Nagata, Jun verfasserin aut Nagasaki, Toshiya verfasserin aut Konishi, Tsuyoshi verfasserin aut Fujimoto, Yoshiya verfasserin aut Nagayama, Satoshi verfasserin aut Fukunaga, Yosuke verfasserin aut Ueno, Masashi verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:22 year:2015 number:Suppl 3 day:21 month:04 pages:614-620 https://dx.doi.org/10.1245/s10434-015-4565-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 22 2015 Suppl 3 21 04 614-620 |
| spelling |
10.1245/s10434-015-4565-5 doi (DE-627)SPR009973605 (SPR)s10434-015-4565-5-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Akiyoshi, Takashi verfasserin aut Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. Total Mesorectal Excision (dpeaa)DE-He213 Magnetic Resonance Imaging Finding (dpeaa)DE-He213 Pelvic Magnetic Resonance Imaging (dpeaa)DE-He213 Lateral Pelvic Lymph Node (dpeaa)DE-He213 Lateral Pelvic Lymph Node Dissection (dpeaa)DE-He213 Matsueda, Kiyoshi verfasserin aut Hiratsuka, Makiko verfasserin aut Unno, Toshiyuki verfasserin aut Nagata, Jun verfasserin aut Nagasaki, Toshiya verfasserin aut Konishi, Tsuyoshi verfasserin aut Fujimoto, Yoshiya verfasserin aut Nagayama, Satoshi verfasserin aut Fukunaga, Yosuke verfasserin aut Ueno, Masashi verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:22 year:2015 number:Suppl 3 day:21 month:04 pages:614-620 https://dx.doi.org/10.1245/s10434-015-4565-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 22 2015 Suppl 3 21 04 614-620 |
| allfields_unstemmed |
10.1245/s10434-015-4565-5 doi (DE-627)SPR009973605 (SPR)s10434-015-4565-5-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Akiyoshi, Takashi verfasserin aut Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. Total Mesorectal Excision (dpeaa)DE-He213 Magnetic Resonance Imaging Finding (dpeaa)DE-He213 Pelvic Magnetic Resonance Imaging (dpeaa)DE-He213 Lateral Pelvic Lymph Node (dpeaa)DE-He213 Lateral Pelvic Lymph Node Dissection (dpeaa)DE-He213 Matsueda, Kiyoshi verfasserin aut Hiratsuka, Makiko verfasserin aut Unno, Toshiyuki verfasserin aut Nagata, Jun verfasserin aut Nagasaki, Toshiya verfasserin aut Konishi, Tsuyoshi verfasserin aut Fujimoto, Yoshiya verfasserin aut Nagayama, Satoshi verfasserin aut Fukunaga, Yosuke verfasserin aut Ueno, Masashi verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:22 year:2015 number:Suppl 3 day:21 month:04 pages:614-620 https://dx.doi.org/10.1245/s10434-015-4565-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 22 2015 Suppl 3 21 04 614-620 |
| allfieldsGer |
10.1245/s10434-015-4565-5 doi (DE-627)SPR009973605 (SPR)s10434-015-4565-5-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Akiyoshi, Takashi verfasserin aut Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. Total Mesorectal Excision (dpeaa)DE-He213 Magnetic Resonance Imaging Finding (dpeaa)DE-He213 Pelvic Magnetic Resonance Imaging (dpeaa)DE-He213 Lateral Pelvic Lymph Node (dpeaa)DE-He213 Lateral Pelvic Lymph Node Dissection (dpeaa)DE-He213 Matsueda, Kiyoshi verfasserin aut Hiratsuka, Makiko verfasserin aut Unno, Toshiyuki verfasserin aut Nagata, Jun verfasserin aut Nagasaki, Toshiya verfasserin aut Konishi, Tsuyoshi verfasserin aut Fujimoto, Yoshiya verfasserin aut Nagayama, Satoshi verfasserin aut Fukunaga, Yosuke verfasserin aut Ueno, Masashi verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:22 year:2015 number:Suppl 3 day:21 month:04 pages:614-620 https://dx.doi.org/10.1245/s10434-015-4565-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 22 2015 Suppl 3 21 04 614-620 |
| allfieldsSound |
10.1245/s10434-015-4565-5 doi (DE-627)SPR009973605 (SPR)s10434-015-4565-5-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Akiyoshi, Takashi verfasserin aut Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. Total Mesorectal Excision (dpeaa)DE-He213 Magnetic Resonance Imaging Finding (dpeaa)DE-He213 Pelvic Magnetic Resonance Imaging (dpeaa)DE-He213 Lateral Pelvic Lymph Node (dpeaa)DE-He213 Lateral Pelvic Lymph Node Dissection (dpeaa)DE-He213 Matsueda, Kiyoshi verfasserin aut Hiratsuka, Makiko verfasserin aut Unno, Toshiyuki verfasserin aut Nagata, Jun verfasserin aut Nagasaki, Toshiya verfasserin aut Konishi, Tsuyoshi verfasserin aut Fujimoto, Yoshiya verfasserin aut Nagayama, Satoshi verfasserin aut Fukunaga, Yosuke verfasserin aut Ueno, Masashi verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:22 year:2015 number:Suppl 3 day:21 month:04 pages:614-620 https://dx.doi.org/10.1245/s10434-015-4565-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 22 2015 Suppl 3 21 04 614-620 |
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Enthalten in Annals of surgical oncology 22(2015), Suppl 3 vom: 21. Apr., Seite 614-620 volume:22 year:2015 number:Suppl 3 day:21 month:04 pages:614-620 |
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Total Mesorectal Excision Magnetic Resonance Imaging Finding Pelvic Magnetic Resonance Imaging Lateral Pelvic Lymph Node Lateral Pelvic Lymph Node Dissection |
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Annals of surgical oncology |
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Akiyoshi, Takashi @@aut@@ Matsueda, Kiyoshi @@aut@@ Hiratsuka, Makiko @@aut@@ Unno, Toshiyuki @@aut@@ Nagata, Jun @@aut@@ Nagasaki, Toshiya @@aut@@ Konishi, Tsuyoshi @@aut@@ Fujimoto, Yoshiya @@aut@@ Nagayama, Satoshi @@aut@@ Fukunaga, Yosuke @@aut@@ Ueno, Masashi @@aut@@ |
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2015-04-21T00:00:00Z |
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Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). 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|
| author |
Akiyoshi, Takashi |
| spellingShingle |
Akiyoshi, Takashi ddc 610 bkl 44.81 bkl 44.65 misc Total Mesorectal Excision misc Magnetic Resonance Imaging Finding misc Pelvic Magnetic Resonance Imaging misc Lateral Pelvic Lymph Node misc Lateral Pelvic Lymph Node Dissection Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer |
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Akiyoshi, Takashi |
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610 - Medicine & health |
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Not Illustrated |
| issn |
1534-4681 |
| topic_title |
610 ASE 44.81 bkl 44.65 bkl Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer Total Mesorectal Excision (dpeaa)DE-He213 Magnetic Resonance Imaging Finding (dpeaa)DE-He213 Pelvic Magnetic Resonance Imaging (dpeaa)DE-He213 Lateral Pelvic Lymph Node (dpeaa)DE-He213 Lateral Pelvic Lymph Node Dissection (dpeaa)DE-He213 |
| topic |
ddc 610 bkl 44.81 bkl 44.65 misc Total Mesorectal Excision misc Magnetic Resonance Imaging Finding misc Pelvic Magnetic Resonance Imaging misc Lateral Pelvic Lymph Node misc Lateral Pelvic Lymph Node Dissection |
| topic_unstemmed |
ddc 610 bkl 44.81 bkl 44.65 misc Total Mesorectal Excision misc Magnetic Resonance Imaging Finding misc Pelvic Magnetic Resonance Imaging misc Lateral Pelvic Lymph Node misc Lateral Pelvic Lymph Node Dissection |
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ddc 610 bkl 44.81 bkl 44.65 misc Total Mesorectal Excision misc Magnetic Resonance Imaging Finding misc Pelvic Magnetic Resonance Imaging misc Lateral Pelvic Lymph Node misc Lateral Pelvic Lymph Node Dissection |
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Annals of surgical oncology |
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343969947 |
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610 - Medicine & health |
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Annals of surgical oncology |
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(DE-627)343969947 (DE-600)2074021-9 |
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Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer |
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(DE-627)SPR009973605 (SPR)s10434-015-4565-5-e |
| title_full |
Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer |
| author_sort |
Akiyoshi, Takashi |
| journal |
Annals of surgical oncology |
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Annals of surgical oncology |
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eng |
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600 - Technology |
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2015 |
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614 |
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Akiyoshi, Takashi Matsueda, Kiyoshi Hiratsuka, Makiko Unno, Toshiyuki Nagata, Jun Nagasaki, Toshiya Konishi, Tsuyoshi Fujimoto, Yoshiya Nagayama, Satoshi Fukunaga, Yosuke Ueno, Masashi |
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610 ASE 44.81 bkl 44.65 bkl |
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Elektronische Aufsätze |
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Akiyoshi, Takashi |
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10.1245/s10434-015-4565-5 |
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610 |
| author2-role |
verfasserin |
| title_sort |
indications for lateral pelvic lymph node dissection based on magnetic resonance imaging before and after preoperative chemoradiotherapy in patients with advanced low-rectal cancer |
| title_auth |
Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer |
| abstract |
Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. |
| abstractGer |
Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. |
| abstract_unstemmed |
Background We assessed the magnetic resonance imaging (MRI) findings of lateral pelvic lymph node (LPLN) metastasis in patients with advanced low-rectal cancer treated with preoperative chemoradiotherapy (CRT) and LPLN dissection (LPLD) for clinically suspected LPLN metastasis. Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). Multivariate analysis showed the independent association of female sex [P = 0.0192; odds ratio (OR) 5.616; 95 % confidence interval (CI) 1.315–28.942], pre-CRT short-axis diameter of the LPLN ≥8 mm (P = 0.0047; OR 9.188; 95 % CI 1.948–54.366), and CRT without induction systemic chemotherapy (P = 0.0285; OR 9.235; 95 % CI 1.241–106.947) with LPLN metastasis. Conclusions MRI before CRT is useful to predict LPLN metastasis and to determine the indications for LPLD. |
| collection_details |
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| container_issue |
Suppl 3 |
| title_short |
Indications for Lateral Pelvic Lymph Node Dissection Based on Magnetic Resonance Imaging Before and After Preoperative Chemoradiotherapy in Patients with Advanced Low-Rectal Cancer |
| url |
https://dx.doi.org/10.1245/s10434-015-4565-5 |
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true |
| author2 |
Matsueda, Kiyoshi Hiratsuka, Makiko Unno, Toshiyuki Nagata, Jun Nagasaki, Toshiya Konishi, Tsuyoshi Fujimoto, Yoshiya Nagayama, Satoshi Fukunaga, Yosuke Ueno, Masashi |
| author2Str |
Matsueda, Kiyoshi Hiratsuka, Makiko Unno, Toshiyuki Nagata, Jun Nagasaki, Toshiya Konishi, Tsuyoshi Fujimoto, Yoshiya Nagayama, Satoshi Fukunaga, Yosuke Ueno, Masashi |
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343969947 |
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c |
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| doi_str |
10.1245/s10434-015-4565-5 |
| up_date |
2024-07-04T03:44:33.673Z |
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1803618535272873984 |
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Our aim was to identify the optimal indications for LPLD. Methods The study population consisted of 77 patients with advanced low-rectal cancer who underwent LPLD for clinically suspicious LPLN metastasis after preoperative CRT. MRI findings before/after CRT, clinical factors, and LPLN metastasis were evaluated. Results LPLN metastasis was confirmed in 31 patients (40.3 %). Metastasis was significantly higher in patients with LPLNs with a short-axis diameter ≥8 mm than in patients with LPLNs with a short-axis diameter <8 mm before CRT (75 vs. 20 %, P < 0.0001). LPLN metastasis was also significantly higher in patients with LPLNs with a short-axis diameter >5 mm than in patients with LPLNs with a short-axis diameter ≤5 mm after CRT (75 vs. 20 %, P < 0.0001). 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| score |
7.396736 |