In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices

Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Livingston, Edward H. [verfasserIn] Gulaka, Praveen [verfasserIn] Kommera, Sarita [verfasserIn] Wang, Boping [verfasserIn] Liu, Hanli [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2008

Schlagwörter:	Bile duct injury Cholecystectomy Spectroscopy Near infrared imaging Injury prevention Iatrogenic injury Near infrared spectroscopy Radial basis function

Übergeordnetes Werk:	Enthalten in: Annals of biomedical engineering - Dordrecht [u.a.] : Springer Science + Business Media B.V, 1972, 37(2008), 1 vom: 16. Okt.
Übergeordnetes Werk:	volume:37 ; year:2008 ; number:1 ; day:16 ; month:10

Links:	Volltext

DOI / URN:	10.1007/s10439-008-9574-0

Katalog-ID:	SPR010043357

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520			\|a Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI.
650		4	\|a Bile duct injury \|7 (dpeaa)DE-He213
650		4	\|a Cholecystectomy \|7 (dpeaa)DE-He213
650		4	\|a Spectroscopy \|7 (dpeaa)DE-He213
650		4	\|a Near infrared imaging \|7 (dpeaa)DE-He213
650		4	\|a Injury prevention \|7 (dpeaa)DE-He213
650		4	\|a Iatrogenic injury \|7 (dpeaa)DE-He213
650		4	\|a Near infrared spectroscopy \|7 (dpeaa)DE-He213
650		4	\|a Radial basis function \|7 (dpeaa)DE-He213
700	1		\|a Gulaka, Praveen \|e verfasserin \|4 aut
700	1		\|a Kommera, Sarita \|e verfasserin \|4 aut
700	1		\|a Wang, Boping \|e verfasserin \|4 aut
700	1		\|a Liu, Hanli \|e verfasserin \|4 aut
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author_variant	e h l eh ehl p g pg s k sk b w bw h l hl
matchkey_str	article:15739686:2008----::niopcrsoicaatrztooprieiirtatisefrttpnhdvlpe
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bklnumber	44.09
publishDate	2008
allfields	10.1007/s10439-008-9574-0 doi (DE-627)SPR010043357 (SPR)s10439-008-9574-0-e DE-627 ger DE-627 rakwb eng 610 ASE 44.09 bkl Livingston, Edward H. verfasserin aut In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI. Bile duct injury (dpeaa)DE-He213 Cholecystectomy (dpeaa)DE-He213 Spectroscopy (dpeaa)DE-He213 Near infrared imaging (dpeaa)DE-He213 Injury prevention (dpeaa)DE-He213 Iatrogenic injury (dpeaa)DE-He213 Near infrared spectroscopy (dpeaa)DE-He213 Radial basis function (dpeaa)DE-He213 Gulaka, Praveen verfasserin aut Kommera, Sarita verfasserin aut Wang, Boping verfasserin aut Liu, Hanli verfasserin aut Enthalten in Annals of biomedical engineering Dordrecht [u.a.] : Springer Science + Business Media B.V, 1972 37(2008), 1 vom: 16. Okt. (DE-627)270424792 (DE-600)1477155-X 1573-9686 nnns volume:37 year:2008 number:1 day:16 month:10 https://dx.doi.org/10.1007/s10439-008-9574-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.09 ASE AR 37 2008 1 16 10
spelling	10.1007/s10439-008-9574-0 doi (DE-627)SPR010043357 (SPR)s10439-008-9574-0-e DE-627 ger DE-627 rakwb eng 610 ASE 44.09 bkl Livingston, Edward H. verfasserin aut In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI. Bile duct injury (dpeaa)DE-He213 Cholecystectomy (dpeaa)DE-He213 Spectroscopy (dpeaa)DE-He213 Near infrared imaging (dpeaa)DE-He213 Injury prevention (dpeaa)DE-He213 Iatrogenic injury (dpeaa)DE-He213 Near infrared spectroscopy (dpeaa)DE-He213 Radial basis function (dpeaa)DE-He213 Gulaka, Praveen verfasserin aut Kommera, Sarita verfasserin aut Wang, Boping verfasserin aut Liu, Hanli verfasserin aut Enthalten in Annals of biomedical engineering Dordrecht [u.a.] : Springer Science + Business Media B.V, 1972 37(2008), 1 vom: 16. Okt. (DE-627)270424792 (DE-600)1477155-X 1573-9686 nnns volume:37 year:2008 number:1 day:16 month:10 https://dx.doi.org/10.1007/s10439-008-9574-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.09 ASE AR 37 2008 1 16 10
allfields_unstemmed	10.1007/s10439-008-9574-0 doi (DE-627)SPR010043357 (SPR)s10439-008-9574-0-e DE-627 ger DE-627 rakwb eng 610 ASE 44.09 bkl Livingston, Edward H. verfasserin aut In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI. Bile duct injury (dpeaa)DE-He213 Cholecystectomy (dpeaa)DE-He213 Spectroscopy (dpeaa)DE-He213 Near infrared imaging (dpeaa)DE-He213 Injury prevention (dpeaa)DE-He213 Iatrogenic injury (dpeaa)DE-He213 Near infrared spectroscopy (dpeaa)DE-He213 Radial basis function (dpeaa)DE-He213 Gulaka, Praveen verfasserin aut Kommera, Sarita verfasserin aut Wang, Boping verfasserin aut Liu, Hanli verfasserin aut Enthalten in Annals of biomedical engineering Dordrecht [u.a.] : Springer Science + Business Media B.V, 1972 37(2008), 1 vom: 16. Okt. (DE-627)270424792 (DE-600)1477155-X 1573-9686 nnns volume:37 year:2008 number:1 day:16 month:10 https://dx.doi.org/10.1007/s10439-008-9574-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.09 ASE AR 37 2008 1 16 10
allfieldsGer	10.1007/s10439-008-9574-0 doi (DE-627)SPR010043357 (SPR)s10439-008-9574-0-e DE-627 ger DE-627 rakwb eng 610 ASE 44.09 bkl Livingston, Edward H. verfasserin aut In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI. Bile duct injury (dpeaa)DE-He213 Cholecystectomy (dpeaa)DE-He213 Spectroscopy (dpeaa)DE-He213 Near infrared imaging (dpeaa)DE-He213 Injury prevention (dpeaa)DE-He213 Iatrogenic injury (dpeaa)DE-He213 Near infrared spectroscopy (dpeaa)DE-He213 Radial basis function (dpeaa)DE-He213 Gulaka, Praveen verfasserin aut Kommera, Sarita verfasserin aut Wang, Boping verfasserin aut Liu, Hanli verfasserin aut Enthalten in Annals of biomedical engineering Dordrecht [u.a.] : Springer Science + Business Media B.V, 1972 37(2008), 1 vom: 16. Okt. (DE-627)270424792 (DE-600)1477155-X 1573-9686 nnns volume:37 year:2008 number:1 day:16 month:10 https://dx.doi.org/10.1007/s10439-008-9574-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.09 ASE AR 37 2008 1 16 10
allfieldsSound	10.1007/s10439-008-9574-0 doi (DE-627)SPR010043357 (SPR)s10439-008-9574-0-e DE-627 ger DE-627 rakwb eng 610 ASE 44.09 bkl Livingston, Edward H. verfasserin aut In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI. Bile duct injury (dpeaa)DE-He213 Cholecystectomy (dpeaa)DE-He213 Spectroscopy (dpeaa)DE-He213 Near infrared imaging (dpeaa)DE-He213 Injury prevention (dpeaa)DE-He213 Iatrogenic injury (dpeaa)DE-He213 Near infrared spectroscopy (dpeaa)DE-He213 Radial basis function (dpeaa)DE-He213 Gulaka, Praveen verfasserin aut Kommera, Sarita verfasserin aut Wang, Boping verfasserin aut Liu, Hanli verfasserin aut Enthalten in Annals of biomedical engineering Dordrecht [u.a.] : Springer Science + Business Media B.V, 1972 37(2008), 1 vom: 16. Okt. (DE-627)270424792 (DE-600)1477155-X 1573-9686 nnns volume:37 year:2008 number:1 day:16 month:10 https://dx.doi.org/10.1007/s10439-008-9574-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.09 ASE AR 37 2008 1 16 10
language	English
source	Enthalten in Annals of biomedical engineering 37(2008), 1 vom: 16. Okt. volume:37 year:2008 number:1 day:16 month:10
sourceStr	Enthalten in Annals of biomedical engineering 37(2008), 1 vom: 16. Okt. volume:37 year:2008 number:1 day:16 month:10
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Bile duct injury Cholecystectomy Spectroscopy Near infrared imaging Injury prevention Iatrogenic injury Near infrared spectroscopy Radial basis function
dewey-raw	610
isfreeaccess_bool	false
container_title	Annals of biomedical engineering
authorswithroles_txt_mv	Livingston, Edward H. @@aut@@ Gulaka, Praveen @@aut@@ Kommera, Sarita @@aut@@ Wang, Boping @@aut@@ Liu, Hanli @@aut@@
publishDateDaySort_date	2008-10-16T00:00:00Z
hierarchy_top_id	270424792
dewey-sort	3610
id	SPR010043357
language_de	englisch
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Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. 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author	Livingston, Edward H.
spellingShingle	Livingston, Edward H. ddc 610 bkl 44.09 misc Bile duct injury misc Cholecystectomy misc Spectroscopy misc Near infrared imaging misc Injury prevention misc Iatrogenic injury misc Near infrared spectroscopy misc Radial basis function In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices
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topic_title	610 ASE 44.09 bkl In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices Bile duct injury (dpeaa)DE-He213 Cholecystectomy (dpeaa)DE-He213 Spectroscopy (dpeaa)DE-He213 Near infrared imaging (dpeaa)DE-He213 Injury prevention (dpeaa)DE-He213 Iatrogenic injury (dpeaa)DE-He213 Near infrared spectroscopy (dpeaa)DE-He213 Radial basis function (dpeaa)DE-He213
topic	ddc 610 bkl 44.09 misc Bile duct injury misc Cholecystectomy misc Spectroscopy misc Near infrared imaging misc Injury prevention misc Iatrogenic injury misc Near infrared spectroscopy misc Radial basis function
topic_unstemmed	ddc 610 bkl 44.09 misc Bile duct injury misc Cholecystectomy misc Spectroscopy misc Near infrared imaging misc Injury prevention misc Iatrogenic injury misc Near infrared spectroscopy misc Radial basis function
topic_browse	ddc 610 bkl 44.09 misc Bile duct injury misc Cholecystectomy misc Spectroscopy misc Near infrared imaging misc Injury prevention misc Iatrogenic injury misc Near infrared spectroscopy misc Radial basis function
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title	In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices
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title_full	In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices
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author_browse	Livingston, Edward H. Gulaka, Praveen Kommera, Sarita Wang, Boping Liu, Hanli
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title_sort	in vivo spectroscopic characterization of porcine biliary tract tissues: first step in the development of new biliary tract imaging devices
title_auth	In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices
abstract	Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI.
abstractGer	Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI.
abstract_unstemmed	Abstract Background Approximately 400,000 cholecystectomies are performed annually in the United States. The most important complication of the operation is bile duct injury (BDI). Injury prevention relies mostly on an individual surgeon’s skill. As of yet no technology has been introduced that will enable surgeons to visualize the bile ducts while operating. Theoretically, such a device could eliminate BDI. Near infrared (NIR) spectroscopy capitalizes on near infrared light’s ability to penetrate deeply into tissues and spectroscopic capability to discern tissue’s chemical properties. The purpose of this work is to characterize the NIR optical properties of bile containing structures that are needed for later development of a clinically useful probe. Methods NIR Spectroscopy combined with visible light spectroscopy was used to determine the spectroscopic properties of the biliary tree and its adjacent structures. Eight anesthetized pigs were used to obtain reflectance measurements using a fiber probe. Radial Basis functions (RBFs) were used to characterize the reflected light spectra. Parameters describing the RBFs were then used to classify tissues based on their observed spectra using machine automation. Results Biliary tissues, arteries and veins all had unique reflectance spectra. These spectra were characterized by their unique set of RBFs. Conclusion We have developed an optical probe capable of imaging and identifying biliary tract tissues in a porcine model. In this study, we characterized the reflectance properties for bile and blood vessels such that when the probe is applied to the porta hepatis it will enable surgeons to localize important biliary structures prior to any portal dissection, potentially eliminating the risk for inadvertent BDI.
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container_issue	1
title_short	In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices
url	https://dx.doi.org/10.1007/s10439-008-9574-0
remote_bool	true
author2	Gulaka, Praveen Kommera, Sarita Wang, Boping Liu, Hanli
author2Str	Gulaka, Praveen Kommera, Sarita Wang, Boping Liu, Hanli
ppnlink	270424792
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isOA_txt	false
hochschulschrift_bool	false
doi_str	10.1007/s10439-008-9574-0
up_date	2024-07-03T13:36:00.806Z
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In Vivo Spectroscopic Characterization of Porcine Biliary Tract Tissues: First Step in the Development of New Biliary Tract Imaging Devices

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