Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients
Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population....
Ausführliche Beschreibung
Autor*in: |
Prinzi, Natalie [verfasserIn] Baldini, Enke [verfasserIn] Sorrenti, Salvatore [verfasserIn] De Vito, Corrado [verfasserIn] Tuccilli, Chiara [verfasserIn] Catania, Antonio [verfasserIn] Carbotta, Sabino [verfasserIn] Mocini, Renzo [verfasserIn] Coccaro, Carmela [verfasserIn] Nesca, Angela [verfasserIn] Bianchini, Marta [verfasserIn] De Antoni, Enrico [verfasserIn] D’Armiento, Massimino [verfasserIn] Ulisse, Salvatore [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Breast cancer research and treatment - Dordrecht [u.a.] : Springer Science + Business Media B.V., 1981, 144(2014), 3 vom: 07. März, Seite 683-688 |
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Übergeordnetes Werk: |
volume:144 ; year:2014 ; number:3 ; day:07 ; month:03 ; pages:683-688 |
Links: |
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DOI / URN: |
10.1007/s10549-014-2893-y |
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Katalog-ID: |
SPR011094613 |
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520 | |a Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. | ||
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700 | 1 | |a Baldini, Enke |e verfasserin |4 aut | |
700 | 1 | |a Sorrenti, Salvatore |e verfasserin |4 aut | |
700 | 1 | |a De Vito, Corrado |e verfasserin |4 aut | |
700 | 1 | |a Tuccilli, Chiara |e verfasserin |4 aut | |
700 | 1 | |a Catania, Antonio |e verfasserin |4 aut | |
700 | 1 | |a Carbotta, Sabino |e verfasserin |4 aut | |
700 | 1 | |a Mocini, Renzo |e verfasserin |4 aut | |
700 | 1 | |a Coccaro, Carmela |e verfasserin |4 aut | |
700 | 1 | |a Nesca, Angela |e verfasserin |4 aut | |
700 | 1 | |a Bianchini, Marta |e verfasserin |4 aut | |
700 | 1 | |a De Antoni, Enrico |e verfasserin |4 aut | |
700 | 1 | |a D’Armiento, Massimino |e verfasserin |4 aut | |
700 | 1 | |a Ulisse, Salvatore |e verfasserin |4 aut | |
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10.1007/s10549-014-2893-y doi (DE-627)SPR011094613 (SPR)s10549-014-2893-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.92 bkl Prinzi, Natalie verfasserin aut Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. Thyroid disease (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Thyroid hormone (dpeaa)DE-He213 Oestrogen (dpeaa)DE-He213 Oestrogen receptor (dpeaa)DE-He213 Thyroid hormone receptor (dpeaa)DE-He213 TSH (dpeaa)DE-He213 Anti-thyroglobulin antibody (dpeaa)DE-He213 Anti-thyroperoxidase antibody (dpeaa)DE-He213 Anti-TSH receptor antibody (dpeaa)DE-He213 Baldini, Enke verfasserin aut Sorrenti, Salvatore verfasserin aut De Vito, Corrado verfasserin aut Tuccilli, Chiara verfasserin aut Catania, Antonio verfasserin aut Carbotta, Sabino verfasserin aut Mocini, Renzo verfasserin aut Coccaro, Carmela verfasserin aut Nesca, Angela verfasserin aut Bianchini, Marta verfasserin aut De Antoni, Enrico verfasserin aut D’Armiento, Massimino verfasserin aut Ulisse, Salvatore verfasserin aut Enthalten in Breast cancer research and treatment Dordrecht [u.a.] : Springer Science + Business Media B.V., 1981 144(2014), 3 vom: 07. März, Seite 683-688 (DE-627)320433722 (DE-600)2004077-5 1573-7217 nnns volume:144 year:2014 number:3 day:07 month:03 pages:683-688 https://dx.doi.org/10.1007/s10549-014-2893-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 144 2014 3 07 03 683-688 |
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10.1007/s10549-014-2893-y doi (DE-627)SPR011094613 (SPR)s10549-014-2893-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.92 bkl Prinzi, Natalie verfasserin aut Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. Thyroid disease (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Thyroid hormone (dpeaa)DE-He213 Oestrogen (dpeaa)DE-He213 Oestrogen receptor (dpeaa)DE-He213 Thyroid hormone receptor (dpeaa)DE-He213 TSH (dpeaa)DE-He213 Anti-thyroglobulin antibody (dpeaa)DE-He213 Anti-thyroperoxidase antibody (dpeaa)DE-He213 Anti-TSH receptor antibody (dpeaa)DE-He213 Baldini, Enke verfasserin aut Sorrenti, Salvatore verfasserin aut De Vito, Corrado verfasserin aut Tuccilli, Chiara verfasserin aut Catania, Antonio verfasserin aut Carbotta, Sabino verfasserin aut Mocini, Renzo verfasserin aut Coccaro, Carmela verfasserin aut Nesca, Angela verfasserin aut Bianchini, Marta verfasserin aut De Antoni, Enrico verfasserin aut D’Armiento, Massimino verfasserin aut Ulisse, Salvatore verfasserin aut Enthalten in Breast cancer research and treatment Dordrecht [u.a.] : Springer Science + Business Media B.V., 1981 144(2014), 3 vom: 07. März, Seite 683-688 (DE-627)320433722 (DE-600)2004077-5 1573-7217 nnns volume:144 year:2014 number:3 day:07 month:03 pages:683-688 https://dx.doi.org/10.1007/s10549-014-2893-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 144 2014 3 07 03 683-688 |
allfields_unstemmed |
10.1007/s10549-014-2893-y doi (DE-627)SPR011094613 (SPR)s10549-014-2893-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.92 bkl Prinzi, Natalie verfasserin aut Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. Thyroid disease (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Thyroid hormone (dpeaa)DE-He213 Oestrogen (dpeaa)DE-He213 Oestrogen receptor (dpeaa)DE-He213 Thyroid hormone receptor (dpeaa)DE-He213 TSH (dpeaa)DE-He213 Anti-thyroglobulin antibody (dpeaa)DE-He213 Anti-thyroperoxidase antibody (dpeaa)DE-He213 Anti-TSH receptor antibody (dpeaa)DE-He213 Baldini, Enke verfasserin aut Sorrenti, Salvatore verfasserin aut De Vito, Corrado verfasserin aut Tuccilli, Chiara verfasserin aut Catania, Antonio verfasserin aut Carbotta, Sabino verfasserin aut Mocini, Renzo verfasserin aut Coccaro, Carmela verfasserin aut Nesca, Angela verfasserin aut Bianchini, Marta verfasserin aut De Antoni, Enrico verfasserin aut D’Armiento, Massimino verfasserin aut Ulisse, Salvatore verfasserin aut Enthalten in Breast cancer research and treatment Dordrecht [u.a.] : Springer Science + Business Media B.V., 1981 144(2014), 3 vom: 07. März, Seite 683-688 (DE-627)320433722 (DE-600)2004077-5 1573-7217 nnns volume:144 year:2014 number:3 day:07 month:03 pages:683-688 https://dx.doi.org/10.1007/s10549-014-2893-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 144 2014 3 07 03 683-688 |
allfieldsGer |
10.1007/s10549-014-2893-y doi (DE-627)SPR011094613 (SPR)s10549-014-2893-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.92 bkl Prinzi, Natalie verfasserin aut Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. Thyroid disease (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Thyroid hormone (dpeaa)DE-He213 Oestrogen (dpeaa)DE-He213 Oestrogen receptor (dpeaa)DE-He213 Thyroid hormone receptor (dpeaa)DE-He213 TSH (dpeaa)DE-He213 Anti-thyroglobulin antibody (dpeaa)DE-He213 Anti-thyroperoxidase antibody (dpeaa)DE-He213 Anti-TSH receptor antibody (dpeaa)DE-He213 Baldini, Enke verfasserin aut Sorrenti, Salvatore verfasserin aut De Vito, Corrado verfasserin aut Tuccilli, Chiara verfasserin aut Catania, Antonio verfasserin aut Carbotta, Sabino verfasserin aut Mocini, Renzo verfasserin aut Coccaro, Carmela verfasserin aut Nesca, Angela verfasserin aut Bianchini, Marta verfasserin aut De Antoni, Enrico verfasserin aut D’Armiento, Massimino verfasserin aut Ulisse, Salvatore verfasserin aut Enthalten in Breast cancer research and treatment Dordrecht [u.a.] : Springer Science + Business Media B.V., 1981 144(2014), 3 vom: 07. März, Seite 683-688 (DE-627)320433722 (DE-600)2004077-5 1573-7217 nnns volume:144 year:2014 number:3 day:07 month:03 pages:683-688 https://dx.doi.org/10.1007/s10549-014-2893-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 144 2014 3 07 03 683-688 |
allfieldsSound |
10.1007/s10549-014-2893-y doi (DE-627)SPR011094613 (SPR)s10549-014-2893-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.92 bkl Prinzi, Natalie verfasserin aut Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. Thyroid disease (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Thyroid hormone (dpeaa)DE-He213 Oestrogen (dpeaa)DE-He213 Oestrogen receptor (dpeaa)DE-He213 Thyroid hormone receptor (dpeaa)DE-He213 TSH (dpeaa)DE-He213 Anti-thyroglobulin antibody (dpeaa)DE-He213 Anti-thyroperoxidase antibody (dpeaa)DE-He213 Anti-TSH receptor antibody (dpeaa)DE-He213 Baldini, Enke verfasserin aut Sorrenti, Salvatore verfasserin aut De Vito, Corrado verfasserin aut Tuccilli, Chiara verfasserin aut Catania, Antonio verfasserin aut Carbotta, Sabino verfasserin aut Mocini, Renzo verfasserin aut Coccaro, Carmela verfasserin aut Nesca, Angela verfasserin aut Bianchini, Marta verfasserin aut De Antoni, Enrico verfasserin aut D’Armiento, Massimino verfasserin aut Ulisse, Salvatore verfasserin aut Enthalten in Breast cancer research and treatment Dordrecht [u.a.] : Springer Science + Business Media B.V., 1981 144(2014), 3 vom: 07. März, Seite 683-688 (DE-627)320433722 (DE-600)2004077-5 1573-7217 nnns volume:144 year:2014 number:3 day:07 month:03 pages:683-688 https://dx.doi.org/10.1007/s10549-014-2893-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 144 2014 3 07 03 683-688 |
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Thyroid disease Breast cancer Thyroid hormone Oestrogen Oestrogen receptor Thyroid hormone receptor TSH Anti-thyroglobulin antibody Anti-thyroperoxidase antibody Anti-TSH receptor antibody |
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Prinzi, Natalie @@aut@@ Baldini, Enke @@aut@@ Sorrenti, Salvatore @@aut@@ De Vito, Corrado @@aut@@ Tuccilli, Chiara @@aut@@ Catania, Antonio @@aut@@ Carbotta, Sabino @@aut@@ Mocini, Renzo @@aut@@ Coccaro, Carmela @@aut@@ Nesca, Angela @@aut@@ Bianchini, Marta @@aut@@ De Antoni, Enrico @@aut@@ D’Armiento, Massimino @@aut@@ Ulisse, Salvatore @@aut@@ |
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2014-03-07T00:00:00Z |
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author |
Prinzi, Natalie |
spellingShingle |
Prinzi, Natalie ddc 610 bkl 44.92 misc Thyroid disease misc Breast cancer misc Thyroid hormone misc Oestrogen misc Oestrogen receptor misc Thyroid hormone receptor misc TSH misc Anti-thyroglobulin antibody misc Anti-thyroperoxidase antibody misc Anti-TSH receptor antibody Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients |
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610 ASE 44.92 bkl Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients Thyroid disease (dpeaa)DE-He213 Breast cancer (dpeaa)DE-He213 Thyroid hormone (dpeaa)DE-He213 Oestrogen (dpeaa)DE-He213 Oestrogen receptor (dpeaa)DE-He213 Thyroid hormone receptor (dpeaa)DE-He213 TSH (dpeaa)DE-He213 Anti-thyroglobulin antibody (dpeaa)DE-He213 Anti-thyroperoxidase antibody (dpeaa)DE-He213 Anti-TSH receptor antibody (dpeaa)DE-He213 |
topic |
ddc 610 bkl 44.92 misc Thyroid disease misc Breast cancer misc Thyroid hormone misc Oestrogen misc Oestrogen receptor misc Thyroid hormone receptor misc TSH misc Anti-thyroglobulin antibody misc Anti-thyroperoxidase antibody misc Anti-TSH receptor antibody |
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ddc 610 bkl 44.92 misc Thyroid disease misc Breast cancer misc Thyroid hormone misc Oestrogen misc Oestrogen receptor misc Thyroid hormone receptor misc TSH misc Anti-thyroglobulin antibody misc Anti-thyroperoxidase antibody misc Anti-TSH receptor antibody |
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ddc 610 bkl 44.92 misc Thyroid disease misc Breast cancer misc Thyroid hormone misc Oestrogen misc Oestrogen receptor misc Thyroid hormone receptor misc TSH misc Anti-thyroglobulin antibody misc Anti-thyroperoxidase antibody misc Anti-TSH receptor antibody |
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Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients |
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Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients |
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Prinzi, Natalie |
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Breast cancer research and treatment |
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Prinzi, Natalie Baldini, Enke Sorrenti, Salvatore De Vito, Corrado Tuccilli, Chiara Catania, Antonio Carbotta, Sabino Mocini, Renzo Coccaro, Carmela Nesca, Angela Bianchini, Marta De Antoni, Enrico D’Armiento, Massimino Ulisse, Salvatore |
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Prinzi, Natalie |
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610 |
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title_sort |
prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients |
title_auth |
Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients |
abstract |
Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. |
abstractGer |
Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. |
abstract_unstemmed |
Abstract Results from national cancer registries reveal an association of thyroid cancers with extra-thyroidal malignancies. In this study, we evaluated the prevalence of breast cancer (BC) in women affected by both benign and malignant thyroid diseases (TD) in comparison to the general population. To this end, 3,921 female patients from central and southern regions of Italy were evaluated. Age-matched analysis of the prevalence of BC was carried out after dividing the patients into three diagnostic categories: (1) 1,149 patients with non-nodular TD; (2) 2350 patients with nodular TD; (3) 422 patients affected by differentiated thyroid cancers. Furthermore, the patients were grouped according to the absence (2,344 patients) or presence (1,453 patients) of anti-thyroglobulin (TgAb) and/or anti-thyroperoxidase (TPOAb) or anti-TSH receptor auto-antibodies (124 patients). BC prevalence in TD patients as a whole was significantly higher compared to the general population, with an odds ratio (OR) of 3.33. Age-matched analysis showed that the risk of a BC in TD patients was higher in younger patients (age 0–44 years), with an OR of 15.24, which decreased with increasing age. Patients without thyroid auto-antibodies showed a higher OR for BC (p = 0.0005) than TD patients with TgAb and/or TPOAb. The results demonstrate that women affected by either benign or malignant thyroid disease have a significantly greater risk of BC, which is higher at a younger age. Furthermore, thyroid auto-antibodies appear to be protective against BC. These findings may contribute to the identification of common genetic and environmental factors underlying this disease association. |
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3 |
title_short |
Prevalence of breast cancer in thyroid diseases: results of a cross-sectional study of 3,921 patients |
url |
https://dx.doi.org/10.1007/s10549-014-2893-y |
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author2 |
Baldini, Enke Sorrenti, Salvatore De Vito, Corrado Tuccilli, Chiara Catania, Antonio Carbotta, Sabino Mocini, Renzo Coccaro, Carmela Nesca, Angela Bianchini, Marta De Antoni, Enrico D’Armiento, Massimino Ulisse, Salvatore |
author2Str |
Baldini, Enke Sorrenti, Salvatore De Vito, Corrado Tuccilli, Chiara Catania, Antonio Carbotta, Sabino Mocini, Renzo Coccaro, Carmela Nesca, Angela Bianchini, Marta De Antoni, Enrico D’Armiento, Massimino Ulisse, Salvatore |
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doi_str |
10.1007/s10549-014-2893-y |
up_date |
2024-07-03T20:24:09.626Z |
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|
score |
7.402545 |