Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)

Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Song, Jin Ah [verfasserIn] Choi, Cheol Young [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Blue light Cortisol Retinal damage Stress

Übergeordnetes Werk:	Enthalten in: Fish physiology and biochemistry - Dordrecht [u.a.] : Springer Science + Business Media B.V, 1986, 45(2018), 1 vom: 29. Sept., Seite 391-400
Übergeordnetes Werk:	volume:45 ; year:2018 ; number:1 ; day:29 ; month:09 ; pages:391-400

Links:	Volltext

DOI / URN:	10.1007/s10695-018-0571-4

Katalog-ID:	SPR012529729

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520			\|a Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity.
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allfields	10.1007/s10695-018-0571-4 doi (DE-627)SPR012529729 (SPR)s10695-018-0571-4-e DE-627 ger DE-627 rakwb eng 590 ASE 42.00 bkl Song, Jin Ah verfasserin aut Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity. Blue light (dpeaa)DE-He213 Cortisol (dpeaa)DE-He213 Retinal damage (dpeaa)DE-He213 Stress (dpeaa)DE-He213 Choi, Cheol Young verfasserin aut Enthalten in Fish physiology and biochemistry Dordrecht [u.a.] : Springer Science + Business Media B.V, 1986 45(2018), 1 vom: 29. Sept., Seite 391-400 (DE-627)320528375 (DE-600)2015453-7 1573-5168 nnns volume:45 year:2018 number:1 day:29 month:09 pages:391-400 https://dx.doi.org/10.1007/s10695-018-0571-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 42.00 ASE AR 45 2018 1 29 09 391-400
spelling	10.1007/s10695-018-0571-4 doi (DE-627)SPR012529729 (SPR)s10695-018-0571-4-e DE-627 ger DE-627 rakwb eng 590 ASE 42.00 bkl Song, Jin Ah verfasserin aut Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity. Blue light (dpeaa)DE-He213 Cortisol (dpeaa)DE-He213 Retinal damage (dpeaa)DE-He213 Stress (dpeaa)DE-He213 Choi, Cheol Young verfasserin aut Enthalten in Fish physiology and biochemistry Dordrecht [u.a.] : Springer Science + Business Media B.V, 1986 45(2018), 1 vom: 29. Sept., Seite 391-400 (DE-627)320528375 (DE-600)2015453-7 1573-5168 nnns volume:45 year:2018 number:1 day:29 month:09 pages:391-400 https://dx.doi.org/10.1007/s10695-018-0571-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 42.00 ASE AR 45 2018 1 29 09 391-400
allfields_unstemmed	10.1007/s10695-018-0571-4 doi (DE-627)SPR012529729 (SPR)s10695-018-0571-4-e DE-627 ger DE-627 rakwb eng 590 ASE 42.00 bkl Song, Jin Ah verfasserin aut Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity. Blue light (dpeaa)DE-He213 Cortisol (dpeaa)DE-He213 Retinal damage (dpeaa)DE-He213 Stress (dpeaa)DE-He213 Choi, Cheol Young verfasserin aut Enthalten in Fish physiology and biochemistry Dordrecht [u.a.] : Springer Science + Business Media B.V, 1986 45(2018), 1 vom: 29. Sept., Seite 391-400 (DE-627)320528375 (DE-600)2015453-7 1573-5168 nnns volume:45 year:2018 number:1 day:29 month:09 pages:391-400 https://dx.doi.org/10.1007/s10695-018-0571-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 42.00 ASE AR 45 2018 1 29 09 391-400
allfieldsGer	10.1007/s10695-018-0571-4 doi (DE-627)SPR012529729 (SPR)s10695-018-0571-4-e DE-627 ger DE-627 rakwb eng 590 ASE 42.00 bkl Song, Jin Ah verfasserin aut Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity. Blue light (dpeaa)DE-He213 Cortisol (dpeaa)DE-He213 Retinal damage (dpeaa)DE-He213 Stress (dpeaa)DE-He213 Choi, Cheol Young verfasserin aut Enthalten in Fish physiology and biochemistry Dordrecht [u.a.] : Springer Science + Business Media B.V, 1986 45(2018), 1 vom: 29. Sept., Seite 391-400 (DE-627)320528375 (DE-600)2015453-7 1573-5168 nnns volume:45 year:2018 number:1 day:29 month:09 pages:391-400 https://dx.doi.org/10.1007/s10695-018-0571-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 42.00 ASE AR 45 2018 1 29 09 391-400
allfieldsSound	10.1007/s10695-018-0571-4 doi (DE-627)SPR012529729 (SPR)s10695-018-0571-4-e DE-627 ger DE-627 rakwb eng 590 ASE 42.00 bkl Song, Jin Ah verfasserin aut Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity. Blue light (dpeaa)DE-He213 Cortisol (dpeaa)DE-He213 Retinal damage (dpeaa)DE-He213 Stress (dpeaa)DE-He213 Choi, Cheol Young verfasserin aut Enthalten in Fish physiology and biochemistry Dordrecht [u.a.] : Springer Science + Business Media B.V, 1986 45(2018), 1 vom: 29. Sept., Seite 391-400 (DE-627)320528375 (DE-600)2015453-7 1573-5168 nnns volume:45 year:2018 number:1 day:29 month:09 pages:391-400 https://dx.doi.org/10.1007/s10695-018-0571-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2360 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 42.00 ASE AR 45 2018 1 29 09 391-400
language	English
source	Enthalten in Fish physiology and biochemistry 45(2018), 1 vom: 29. Sept., Seite 391-400 volume:45 year:2018 number:1 day:29 month:09 pages:391-400
sourceStr	Enthalten in Fish physiology and biochemistry 45(2018), 1 vom: 29. Sept., Seite 391-400 volume:45 year:2018 number:1 day:29 month:09 pages:391-400
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Blue light Cortisol Retinal damage Stress
dewey-raw	590
isfreeaccess_bool	false
container_title	Fish physiology and biochemistry
authorswithroles_txt_mv	Song, Jin Ah @@aut@@ Choi, Cheol Young @@aut@@
publishDateDaySort_date	2018-09-29T00:00:00Z
hierarchy_top_id	320528375
dewey-sort	3590
id	SPR012529729
language_de	englisch
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author	Song, Jin Ah
spellingShingle	Song, Jin Ah ddc 590 bkl 42.00 misc Blue light misc Cortisol misc Retinal damage misc Stress Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)
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topic_title	590 ASE 42.00 bkl Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus) Blue light (dpeaa)DE-He213 Cortisol (dpeaa)DE-He213 Retinal damage (dpeaa)DE-He213 Stress (dpeaa)DE-He213
topic	ddc 590 bkl 42.00 misc Blue light misc Cortisol misc Retinal damage misc Stress
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title	Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)
ctrlnum	(DE-627)SPR012529729 (SPR)s10695-018-0571-4-e
title_full	Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)
author_sort	Song, Jin Ah
journal	Fish physiology and biochemistry
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author_browse	Song, Jin Ah Choi, Cheol Young
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title_sort	effects of blue light spectra on retinal stress and damage in goldfish (carassius auratus)
title_auth	Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)
abstract	Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity.
abstractGer	Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity.
abstract_unstemmed	Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. Irradiation with blue light for longer than 1 week induced increased retinal stress and may induce apoptosis in the retinas of goldfish, even at a low intensity.
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title_short	Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)
url	https://dx.doi.org/10.1007/s10695-018-0571-4
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doi_str	10.1007/s10695-018-0571-4
up_date	2024-07-03T13:33:14.484Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR012529729</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20220110234326.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201005s2018 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s10695-018-0571-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR012529729</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s10695-018-0571-4-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">590</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">42.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Song, Jin Ah</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract There have been a number of studies on the negative effects of blue light exposure in various species; however, little information is available on the impacts of blue light intensity and duration on fish. We investigated the effects of blue light spectra on stress in the retinas of goldfish, using a blue (460 nm) light-emitting diode (LED) at three intensities (0.5, 1.0, and 1.5 W/$ m^{2} $). The experiment was conducted for 4 weeks, and sampling was performed at intervals of 1 week. We measured changes in the expression of cortisol, and the concentrations of hydrogen peroxide ($ H_{2} %$ O_{2} $), melanin-concentrating hormone receptor (MCH-R), and caspase-3 in the retinas of goldfish. In addition, we measured histological changes in the retina. We used a transferase dUTP nick end labeling (TUNEL) assay to evaluate the apoptotic response to blue LED spectra. Levels of cortisol, $ H_{2} %$ O_{2} $, MCH-R, and caspase-3 increased with exposure time and light intensity. Histological analysis revealed that the thickness of melanin granules increased with exposure time and light intensity. The progressive TUNEL assay revealed many apoptotic cells after exposure to blue LED light, increasing with exposure time and light intensity. 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Effects of blue light spectra on retinal stress and damage in goldfish (Carassius auratus)

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