Organotropism of Breast Cancer Metastasis
Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier specul...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Lu, Xin [verfasserIn] Kang, Yibin [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2007 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Journal of mammary gland biology and neoplasia - Dordrecht [u.a.] : Springer Science + Business Media B.V, 1996, 12(2007), 2-3 vom: 14. Juni |
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| Übergeordnetes Werk: |
volume:12 ; year:2007 ; number:2-3 ; day:14 ; month:06 |
| Links: |
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| DOI / URN: |
10.1007/s10911-007-9047-3 |
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| Katalog-ID: |
SPR01456095X |
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| 520 | |a Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier speculations that metastasis is a non-random process and is dependent on intricate tumor-stroma interactions at the target organ. Both the intrinsic properties of breast cancer cells and the host organ microenvironment are important in determining the efficiency of organ-specific metastasis. Advances in animal modeling, in vivo imaging and functional genomics have accelerated the discovery of important molecular mediators of organ-specific metastasis. A conceptual framework of breast cancer organotropism is emerging and will be instrumental in guiding future efforts in this exciting research field. | ||
| 650 | 4 | |a Breast cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Metastasis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Organotropism |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Tissue-specific metastasis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Bone metastasis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Lung metastasis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cancer stem cell |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Metastasis niche |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Kang, Yibin |e verfasserin |4 aut | |
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| 912 | |a GBV_ILN_2110 | ||
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10.1007/s10911-007-9047-3 doi (DE-627)SPR01456095X (SPR)s10911-007-9047-3-e DE-627 ger DE-627 rakwb eng 570 610 ASE 44.92 bkl Lu, Xin verfasserin aut Organotropism of Breast Cancer Metastasis 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier speculations that metastasis is a non-random process and is dependent on intricate tumor-stroma interactions at the target organ. Both the intrinsic properties of breast cancer cells and the host organ microenvironment are important in determining the efficiency of organ-specific metastasis. Advances in animal modeling, in vivo imaging and functional genomics have accelerated the discovery of important molecular mediators of organ-specific metastasis. A conceptual framework of breast cancer organotropism is emerging and will be instrumental in guiding future efforts in this exciting research field. Breast cancer (dpeaa)DE-He213 Metastasis (dpeaa)DE-He213 Organotropism (dpeaa)DE-He213 Tissue-specific metastasis (dpeaa)DE-He213 Bone metastasis (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Cancer stem cell (dpeaa)DE-He213 Metastasis niche (dpeaa)DE-He213 Kang, Yibin verfasserin aut Enthalten in Journal of mammary gland biology and neoplasia Dordrecht [u.a.] : Springer Science + Business Media B.V, 1996 12(2007), 2-3 vom: 14. Juni (DE-627)300595778 (DE-600)1483136-3 1573-7039 nnns volume:12 year:2007 number:2-3 day:14 month:06 https://dx.doi.org/10.1007/s10911-007-9047-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 12 2007 2-3 14 06 |
| spelling |
10.1007/s10911-007-9047-3 doi (DE-627)SPR01456095X (SPR)s10911-007-9047-3-e DE-627 ger DE-627 rakwb eng 570 610 ASE 44.92 bkl Lu, Xin verfasserin aut Organotropism of Breast Cancer Metastasis 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier speculations that metastasis is a non-random process and is dependent on intricate tumor-stroma interactions at the target organ. Both the intrinsic properties of breast cancer cells and the host organ microenvironment are important in determining the efficiency of organ-specific metastasis. Advances in animal modeling, in vivo imaging and functional genomics have accelerated the discovery of important molecular mediators of organ-specific metastasis. A conceptual framework of breast cancer organotropism is emerging and will be instrumental in guiding future efforts in this exciting research field. Breast cancer (dpeaa)DE-He213 Metastasis (dpeaa)DE-He213 Organotropism (dpeaa)DE-He213 Tissue-specific metastasis (dpeaa)DE-He213 Bone metastasis (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Cancer stem cell (dpeaa)DE-He213 Metastasis niche (dpeaa)DE-He213 Kang, Yibin verfasserin aut Enthalten in Journal of mammary gland biology and neoplasia Dordrecht [u.a.] : Springer Science + Business Media B.V, 1996 12(2007), 2-3 vom: 14. Juni (DE-627)300595778 (DE-600)1483136-3 1573-7039 nnns volume:12 year:2007 number:2-3 day:14 month:06 https://dx.doi.org/10.1007/s10911-007-9047-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.92 ASE AR 12 2007 2-3 14 06 |
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Enthalten in Journal of mammary gland biology and neoplasia 12(2007), 2-3 vom: 14. Juni volume:12 year:2007 number:2-3 day:14 month:06 |
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Breast cancer Metastasis Organotropism Tissue-specific metastasis Bone metastasis Lung metastasis Cancer stem cell Metastasis niche |
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Journal of mammary gland biology and neoplasia |
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Lu, Xin @@aut@@ Kang, Yibin @@aut@@ |
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Lu, Xin |
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Lu, Xin ddc 570 bkl 44.92 misc Breast cancer misc Metastasis misc Organotropism misc Tissue-specific metastasis misc Bone metastasis misc Lung metastasis misc Cancer stem cell misc Metastasis niche Organotropism of Breast Cancer Metastasis |
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570 610 ASE 44.92 bkl Organotropism of Breast Cancer Metastasis Breast cancer (dpeaa)DE-He213 Metastasis (dpeaa)DE-He213 Organotropism (dpeaa)DE-He213 Tissue-specific metastasis (dpeaa)DE-He213 Bone metastasis (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Cancer stem cell (dpeaa)DE-He213 Metastasis niche (dpeaa)DE-He213 |
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ddc 570 bkl 44.92 misc Breast cancer misc Metastasis misc Organotropism misc Tissue-specific metastasis misc Bone metastasis misc Lung metastasis misc Cancer stem cell misc Metastasis niche |
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ddc 570 bkl 44.92 misc Breast cancer misc Metastasis misc Organotropism misc Tissue-specific metastasis misc Bone metastasis misc Lung metastasis misc Cancer stem cell misc Metastasis niche |
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organotropism of breast cancer metastasis |
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Organotropism of Breast Cancer Metastasis |
| abstract |
Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier speculations that metastasis is a non-random process and is dependent on intricate tumor-stroma interactions at the target organ. Both the intrinsic properties of breast cancer cells and the host organ microenvironment are important in determining the efficiency of organ-specific metastasis. Advances in animal modeling, in vivo imaging and functional genomics have accelerated the discovery of important molecular mediators of organ-specific metastasis. A conceptual framework of breast cancer organotropism is emerging and will be instrumental in guiding future efforts in this exciting research field. |
| abstractGer |
Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier speculations that metastasis is a non-random process and is dependent on intricate tumor-stroma interactions at the target organ. Both the intrinsic properties of breast cancer cells and the host organ microenvironment are important in determining the efficiency of organ-specific metastasis. Advances in animal modeling, in vivo imaging and functional genomics have accelerated the discovery of important molecular mediators of organ-specific metastasis. A conceptual framework of breast cancer organotropism is emerging and will be instrumental in guiding future efforts in this exciting research field. |
| abstract_unstemmed |
Abstract Breast cancer causes mortality by metastasizing to a variety of vital organs, such as bone, lung, brain and liver. Effective therapeutic intervention of this deadly process relies on a better mechanistic understanding of metastasis organotropism. Recent studies have confirmed earlier speculations that metastasis is a non-random process and is dependent on intricate tumor-stroma interactions at the target organ. Both the intrinsic properties of breast cancer cells and the host organ microenvironment are important in determining the efficiency of organ-specific metastasis. Advances in animal modeling, in vivo imaging and functional genomics have accelerated the discovery of important molecular mediators of organ-specific metastasis. A conceptual framework of breast cancer organotropism is emerging and will be instrumental in guiding future efforts in this exciting research field. |
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Organotropism of Breast Cancer Metastasis |
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Kang, Yibin |
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2024-07-04T02:15:37.888Z |
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| score |
7.4010296 |