Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing
Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding bet...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Kim, Ill Yong [verfasserIn] Ohtsuki, Chikara [verfasserIn] Kawachi, Giichiro [verfasserIn] Kamitakahara, Masanobu [verfasserIn] Cho, Sung-Baek [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2007 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Journal of sol gel science and technology - Dordrecht [u.a.] : Springer Science + Business Media B.V, 1993, 45(2007), 1 vom: 23. Okt., Seite 43-49 |
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| Übergeordnetes Werk: |
volume:45 ; year:2007 ; number:1 ; day:23 ; month:10 ; pages:43-49 |
| Links: |
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| DOI / URN: |
10.1007/s10971-007-1634-7 |
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| Katalog-ID: |
SPR015239012 |
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| 520 | |a Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. | ||
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| 650 | 4 | |a Microsphere |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Sol–gel processing |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Polyethyleneglycol |7 (dpeaa)DE-He213 | |
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| 700 | 1 | |a Cho, Sung-Baek |e verfasserin |4 aut | |
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10.1007/s10971-007-1634-7 doi (DE-627)SPR015239012 (SPR)s10971-007-1634-7-e DE-627 ger DE-627 rakwb eng 600 670 ASE 35.18 bkl 51.60 bkl Kim, Ill Yong verfasserin aut Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. Bioactivity (dpeaa)DE-He213 Apatite formation (dpeaa)DE-He213 Microsphere (dpeaa)DE-He213 Sol–gel processing (dpeaa)DE-He213 Polyethyleneglycol (dpeaa)DE-He213 Silane coupling agent (dpeaa)DE-He213 Ohtsuki, Chikara verfasserin aut Kawachi, Giichiro verfasserin aut Kamitakahara, Masanobu verfasserin aut Cho, Sung-Baek verfasserin aut Enthalten in Journal of sol gel science and technology Dordrecht [u.a.] : Springer Science + Business Media B.V, 1993 45(2007), 1 vom: 23. Okt., Seite 43-49 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:45 year:2007 number:1 day:23 month:10 pages:43-49 https://dx.doi.org/10.1007/s10971-007-1634-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.18 ASE 51.60 ASE AR 45 2007 1 23 10 43-49 |
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10.1007/s10971-007-1634-7 doi (DE-627)SPR015239012 (SPR)s10971-007-1634-7-e DE-627 ger DE-627 rakwb eng 600 670 ASE 35.18 bkl 51.60 bkl Kim, Ill Yong verfasserin aut Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. Bioactivity (dpeaa)DE-He213 Apatite formation (dpeaa)DE-He213 Microsphere (dpeaa)DE-He213 Sol–gel processing (dpeaa)DE-He213 Polyethyleneglycol (dpeaa)DE-He213 Silane coupling agent (dpeaa)DE-He213 Ohtsuki, Chikara verfasserin aut Kawachi, Giichiro verfasserin aut Kamitakahara, Masanobu verfasserin aut Cho, Sung-Baek verfasserin aut Enthalten in Journal of sol gel science and technology Dordrecht [u.a.] : Springer Science + Business Media B.V, 1993 45(2007), 1 vom: 23. Okt., Seite 43-49 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:45 year:2007 number:1 day:23 month:10 pages:43-49 https://dx.doi.org/10.1007/s10971-007-1634-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.18 ASE 51.60 ASE AR 45 2007 1 23 10 43-49 |
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10.1007/s10971-007-1634-7 doi (DE-627)SPR015239012 (SPR)s10971-007-1634-7-e DE-627 ger DE-627 rakwb eng 600 670 ASE 35.18 bkl 51.60 bkl Kim, Ill Yong verfasserin aut Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. Bioactivity (dpeaa)DE-He213 Apatite formation (dpeaa)DE-He213 Microsphere (dpeaa)DE-He213 Sol–gel processing (dpeaa)DE-He213 Polyethyleneglycol (dpeaa)DE-He213 Silane coupling agent (dpeaa)DE-He213 Ohtsuki, Chikara verfasserin aut Kawachi, Giichiro verfasserin aut Kamitakahara, Masanobu verfasserin aut Cho, Sung-Baek verfasserin aut Enthalten in Journal of sol gel science and technology Dordrecht [u.a.] : Springer Science + Business Media B.V, 1993 45(2007), 1 vom: 23. Okt., Seite 43-49 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:45 year:2007 number:1 day:23 month:10 pages:43-49 https://dx.doi.org/10.1007/s10971-007-1634-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.18 ASE 51.60 ASE AR 45 2007 1 23 10 43-49 |
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10.1007/s10971-007-1634-7 doi (DE-627)SPR015239012 (SPR)s10971-007-1634-7-e DE-627 ger DE-627 rakwb eng 600 670 ASE 35.18 bkl 51.60 bkl Kim, Ill Yong verfasserin aut Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. Bioactivity (dpeaa)DE-He213 Apatite formation (dpeaa)DE-He213 Microsphere (dpeaa)DE-He213 Sol–gel processing (dpeaa)DE-He213 Polyethyleneglycol (dpeaa)DE-He213 Silane coupling agent (dpeaa)DE-He213 Ohtsuki, Chikara verfasserin aut Kawachi, Giichiro verfasserin aut Kamitakahara, Masanobu verfasserin aut Cho, Sung-Baek verfasserin aut Enthalten in Journal of sol gel science and technology Dordrecht [u.a.] : Springer Science + Business Media B.V, 1993 45(2007), 1 vom: 23. Okt., Seite 43-49 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:45 year:2007 number:1 day:23 month:10 pages:43-49 https://dx.doi.org/10.1007/s10971-007-1634-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.18 ASE 51.60 ASE AR 45 2007 1 23 10 43-49 |
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10.1007/s10971-007-1634-7 doi (DE-627)SPR015239012 (SPR)s10971-007-1634-7-e DE-627 ger DE-627 rakwb eng 600 670 ASE 35.18 bkl 51.60 bkl Kim, Ill Yong verfasserin aut Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. Bioactivity (dpeaa)DE-He213 Apatite formation (dpeaa)DE-He213 Microsphere (dpeaa)DE-He213 Sol–gel processing (dpeaa)DE-He213 Polyethyleneglycol (dpeaa)DE-He213 Silane coupling agent (dpeaa)DE-He213 Ohtsuki, Chikara verfasserin aut Kawachi, Giichiro verfasserin aut Kamitakahara, Masanobu verfasserin aut Cho, Sung-Baek verfasserin aut Enthalten in Journal of sol gel science and technology Dordrecht [u.a.] : Springer Science + Business Media B.V, 1993 45(2007), 1 vom: 23. Okt., Seite 43-49 (DE-627)268757607 (DE-600)1472726-2 1573-4846 nnns volume:45 year:2007 number:1 day:23 month:10 pages:43-49 https://dx.doi.org/10.1007/s10971-007-1634-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.18 ASE 51.60 ASE AR 45 2007 1 23 10 43-49 |
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Enthalten in Journal of sol gel science and technology 45(2007), 1 vom: 23. Okt., Seite 43-49 volume:45 year:2007 number:1 day:23 month:10 pages:43-49 |
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Enthalten in Journal of sol gel science and technology 45(2007), 1 vom: 23. Okt., Seite 43-49 volume:45 year:2007 number:1 day:23 month:10 pages:43-49 |
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Bioactivity Apatite formation Microsphere Sol–gel processing Polyethyleneglycol Silane coupling agent |
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Kim, Ill Yong @@aut@@ Ohtsuki, Chikara @@aut@@ Kawachi, Giichiro @@aut@@ Kamitakahara, Masanobu @@aut@@ Cho, Sung-Baek @@aut@@ |
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2007-10-23T00:00:00Z |
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Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. 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|
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Kim, Ill Yong |
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Kim, Ill Yong ddc 600 bkl 35.18 bkl 51.60 misc Bioactivity misc Apatite formation misc Microsphere misc Sol–gel processing misc Polyethyleneglycol misc Silane coupling agent Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing |
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600 670 ASE 35.18 bkl 51.60 bkl Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing Bioactivity (dpeaa)DE-He213 Apatite formation (dpeaa)DE-He213 Microsphere (dpeaa)DE-He213 Sol–gel processing (dpeaa)DE-He213 Polyethyleneglycol (dpeaa)DE-He213 Silane coupling agent (dpeaa)DE-He213 |
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ddc 600 bkl 35.18 bkl 51.60 misc Bioactivity misc Apatite formation misc Microsphere misc Sol–gel processing misc Polyethyleneglycol misc Silane coupling agent |
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ddc 600 bkl 35.18 bkl 51.60 misc Bioactivity misc Apatite formation misc Microsphere misc Sol–gel processing misc Polyethyleneglycol misc Silane coupling agent |
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ddc 600 bkl 35.18 bkl 51.60 misc Bioactivity misc Apatite formation misc Microsphere misc Sol–gel processing misc Polyethyleneglycol misc Silane coupling agent |
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Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing |
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Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing |
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Kim, Ill Yong Ohtsuki, Chikara Kawachi, Giichiro Kamitakahara, Masanobu Cho, Sung-Baek |
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Elektronische Aufsätze |
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Kim, Ill Yong |
| doi_str_mv |
10.1007/s10971-007-1634-7 |
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600 670 |
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verfasserin |
| title_sort |
preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing |
| title_auth |
Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing |
| abstract |
Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. |
| abstractGer |
Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. |
| abstract_unstemmed |
Abstract Bioactive ceramics show specific biological activity, a bone-bonding ability, and are used as bone-repairing materials. Particles of bioactive ceramics may be used as fillers for fabricating bioactive composites where bioactive fillers are dispersed in a polymer matrix. Chemical bonding between the filler and the organic matrix requires an effective organic modification of the bioactive filler. Previous studies have reported that inorganic glasses in the CaO–$ SiO_{2} $ system act as fundamental components showing bioactivity, as they show a high potential to form bone-like apatite after exposure to a body fluid. Therefore, organically modified microspheres composed of CaO–$ SiO_{2} $ gels can be useful as bioactive fillers to produce bioactive composites. In this study, the conditions for the preparation of organically modified gels composed of CaO–$ SiO_{2} $ were investigated using sol–gel processing of tetraethoxysilane, calcium nitrate tetrahydrate and silane coupling agents (SCAs), such as 3-methacryloxypropyltrimethoxysilane, vinyltrimethoxysilane, and 3-glycidoxypropyltrimethoxysilane (GPS), along with polyethyleneglycol (PEG). Spherical particles with diameter of 2–3 μm were obtained when adding the SCAs, except for GPS with PEG. Incorporation of the SCAs was confirmed using Fourier transform infrared spectroscopy. All the samples prepared with the SCAs formed bone-like apatite on their surfaces in a simulated body fluid within a period of 1 day. These results indicate that bioactive microspheres of organically modified CaO–$ SiO_{2} $ gels can be obtained using sol–gel processing with SCAs. |
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Preparation of bioactive microspheres of organic modified calcium silicates through sol–gel processing |
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Ohtsuki, Chikara Kawachi, Giichiro Kamitakahara, Masanobu Cho, Sung-Baek |
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| score |
7.4025126 |