Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis
Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Yazdanparast, Seyed Amir [verfasserIn] Khodavaisy, Sadegh [verfasserIn] Fakhim, Hamed [verfasserIn] Shokohi, Tahereh [verfasserIn] Haghani, Iman [verfasserIn] Nabili, Mojtaba [verfasserIn] Gholami, Haniyeh [verfasserIn] Ahmadi, Imaneh [verfasserIn] Badali, Hamid [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Mycopathologia - Dordrecht [u.a.] : Springer Science + Business Media B.V., 1938, 180(2015), 5-6 vom: 17. Juli, Seite 317-323 |
|---|---|
| Übergeordnetes Werk: |
volume:180 ; year:2015 ; number:5-6 ; day:17 ; month:07 ; pages:317-323 |
| Links: |
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| DOI / URN: |
10.1007/s11046-015-9924-z |
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| Katalog-ID: |
SPR016269411 |
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| 520 | |a Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. | ||
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10.1007/s11046-015-9924-z doi (DE-627)SPR016269411 (SPR)s11046-015-9924-z-e DE-627 ger DE-627 rakwb eng 570 ASE 44.00 bkl Yazdanparast, Seyed Amir verfasserin aut Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. VVC (dpeaa)DE-He213 . (dpeaa)DE-He213 hwp1 (dpeaa)DE-He213 In vitro susceptibility (dpeaa)DE-He213 Iran (dpeaa)DE-He213 Khodavaisy, Sadegh verfasserin aut Fakhim, Hamed verfasserin aut Shokohi, Tahereh verfasserin aut Haghani, Iman verfasserin aut Nabili, Mojtaba verfasserin aut Gholami, Haniyeh verfasserin aut Ahmadi, Imaneh verfasserin aut Badali, Hamid verfasserin aut Enthalten in Mycopathologia Dordrecht [u.a.] : Springer Science + Business Media B.V., 1938 180(2015), 5-6 vom: 17. Juli, Seite 317-323 (DE-627)320430022 (DE-600)2003647-4 1573-0832 nnns volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 https://dx.doi.org/10.1007/s11046-015-9924-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.00 ASE AR 180 2015 5-6 17 07 317-323 |
| spelling |
10.1007/s11046-015-9924-z doi (DE-627)SPR016269411 (SPR)s11046-015-9924-z-e DE-627 ger DE-627 rakwb eng 570 ASE 44.00 bkl Yazdanparast, Seyed Amir verfasserin aut Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. VVC (dpeaa)DE-He213 . (dpeaa)DE-He213 hwp1 (dpeaa)DE-He213 In vitro susceptibility (dpeaa)DE-He213 Iran (dpeaa)DE-He213 Khodavaisy, Sadegh verfasserin aut Fakhim, Hamed verfasserin aut Shokohi, Tahereh verfasserin aut Haghani, Iman verfasserin aut Nabili, Mojtaba verfasserin aut Gholami, Haniyeh verfasserin aut Ahmadi, Imaneh verfasserin aut Badali, Hamid verfasserin aut Enthalten in Mycopathologia Dordrecht [u.a.] : Springer Science + Business Media B.V., 1938 180(2015), 5-6 vom: 17. Juli, Seite 317-323 (DE-627)320430022 (DE-600)2003647-4 1573-0832 nnns volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 https://dx.doi.org/10.1007/s11046-015-9924-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.00 ASE AR 180 2015 5-6 17 07 317-323 |
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10.1007/s11046-015-9924-z doi (DE-627)SPR016269411 (SPR)s11046-015-9924-z-e DE-627 ger DE-627 rakwb eng 570 ASE 44.00 bkl Yazdanparast, Seyed Amir verfasserin aut Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. VVC (dpeaa)DE-He213 . (dpeaa)DE-He213 hwp1 (dpeaa)DE-He213 In vitro susceptibility (dpeaa)DE-He213 Iran (dpeaa)DE-He213 Khodavaisy, Sadegh verfasserin aut Fakhim, Hamed verfasserin aut Shokohi, Tahereh verfasserin aut Haghani, Iman verfasserin aut Nabili, Mojtaba verfasserin aut Gholami, Haniyeh verfasserin aut Ahmadi, Imaneh verfasserin aut Badali, Hamid verfasserin aut Enthalten in Mycopathologia Dordrecht [u.a.] : Springer Science + Business Media B.V., 1938 180(2015), 5-6 vom: 17. Juli, Seite 317-323 (DE-627)320430022 (DE-600)2003647-4 1573-0832 nnns volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 https://dx.doi.org/10.1007/s11046-015-9924-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.00 ASE AR 180 2015 5-6 17 07 317-323 |
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10.1007/s11046-015-9924-z doi (DE-627)SPR016269411 (SPR)s11046-015-9924-z-e DE-627 ger DE-627 rakwb eng 570 ASE 44.00 bkl Yazdanparast, Seyed Amir verfasserin aut Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. VVC (dpeaa)DE-He213 . (dpeaa)DE-He213 hwp1 (dpeaa)DE-He213 In vitro susceptibility (dpeaa)DE-He213 Iran (dpeaa)DE-He213 Khodavaisy, Sadegh verfasserin aut Fakhim, Hamed verfasserin aut Shokohi, Tahereh verfasserin aut Haghani, Iman verfasserin aut Nabili, Mojtaba verfasserin aut Gholami, Haniyeh verfasserin aut Ahmadi, Imaneh verfasserin aut Badali, Hamid verfasserin aut Enthalten in Mycopathologia Dordrecht [u.a.] : Springer Science + Business Media B.V., 1938 180(2015), 5-6 vom: 17. Juli, Seite 317-323 (DE-627)320430022 (DE-600)2003647-4 1573-0832 nnns volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 https://dx.doi.org/10.1007/s11046-015-9924-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.00 ASE AR 180 2015 5-6 17 07 317-323 |
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10.1007/s11046-015-9924-z doi (DE-627)SPR016269411 (SPR)s11046-015-9924-z-e DE-627 ger DE-627 rakwb eng 570 ASE 44.00 bkl Yazdanparast, Seyed Amir verfasserin aut Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. VVC (dpeaa)DE-He213 . (dpeaa)DE-He213 hwp1 (dpeaa)DE-He213 In vitro susceptibility (dpeaa)DE-He213 Iran (dpeaa)DE-He213 Khodavaisy, Sadegh verfasserin aut Fakhim, Hamed verfasserin aut Shokohi, Tahereh verfasserin aut Haghani, Iman verfasserin aut Nabili, Mojtaba verfasserin aut Gholami, Haniyeh verfasserin aut Ahmadi, Imaneh verfasserin aut Badali, Hamid verfasserin aut Enthalten in Mycopathologia Dordrecht [u.a.] : Springer Science + Business Media B.V., 1938 180(2015), 5-6 vom: 17. Juli, Seite 317-323 (DE-627)320430022 (DE-600)2003647-4 1573-0832 nnns volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 https://dx.doi.org/10.1007/s11046-015-9924-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.00 ASE AR 180 2015 5-6 17 07 317-323 |
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Enthalten in Mycopathologia 180(2015), 5-6 vom: 17. Juli, Seite 317-323 volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 |
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Enthalten in Mycopathologia 180(2015), 5-6 vom: 17. Juli, Seite 317-323 volume:180 year:2015 number:5-6 day:17 month:07 pages:317-323 |
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VVC . hwp1 In vitro susceptibility Iran |
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Mycopathologia |
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Yazdanparast, Seyed Amir @@aut@@ Khodavaisy, Sadegh @@aut@@ Fakhim, Hamed @@aut@@ Shokohi, Tahereh @@aut@@ Haghani, Iman @@aut@@ Nabili, Mojtaba @@aut@@ Gholami, Haniyeh @@aut@@ Ahmadi, Imaneh @@aut@@ Badali, Hamid @@aut@@ |
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This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. 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|
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Yazdanparast, Seyed Amir |
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570 ASE 44.00 bkl Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis VVC (dpeaa)DE-He213 . (dpeaa)DE-He213 hwp1 (dpeaa)DE-He213 In vitro susceptibility (dpeaa)DE-He213 Iran (dpeaa)DE-He213 |
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Yazdanparast, Seyed Amir Khodavaisy, Sadegh Fakhim, Hamed Shokohi, Tahereh Haghani, Iman Nabili, Mojtaba Gholami, Haniyeh Ahmadi, Imaneh Badali, Hamid |
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molecular characterization of highly susceptible candidaafricana from vulvovaginal candidiasis |
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Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis |
| abstract |
Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. |
| abstractGer |
Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. |
| abstract_unstemmed |
Abstract Phylogenetic studies highlight Candidaafricana as an atypical variant within Candidaalbicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44 %) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07 %) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61 %) out of 114 isolates were identified as C. albicans, while five (4.38 %) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-$ log_{2} $-dilution steps less active than amphotericin B, which in turn was 2-$ log_{2} $-dilution steps and 3-$ log_{2} $-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates. |
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Molecular Characterization of Highly Susceptible Candidaafricana from Vulvovaginal Candidiasis |
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| score |
7.4028063 |