Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus)
Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information...
Ausführliche Beschreibung
Autor*in: |
Javanmard, A. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2008 |
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Schlagwörter: |
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Anmerkung: |
© MAIK Nauka 2008 |
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Übergeordnetes Werk: |
Enthalten in: Russian journal of genetics - Moscow : MAIK Nauka/Interperiodica Publ., 1996, 44(2008), 4 vom: Apr., Seite 495-497 |
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Übergeordnetes Werk: |
volume:44 ; year:2008 ; number:4 ; month:04 ; pages:495-497 |
Links: |
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DOI / URN: |
10.1134/S1022795408040169 |
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Katalog-ID: |
SPR017455901 |
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100 | 1 | |a Javanmard, A. |e verfasserin |4 aut | |
245 | 1 | 0 | |a Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) |
264 | 1 | |c 2008 | |
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500 | |a © MAIK Nauka 2008 | ||
520 | |a Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. | ||
650 | 4 | |a Hair Root |7 (dpeaa)DE-He213 | |
650 | 4 | |a Feed Intake |7 (dpeaa)DE-He213 | |
650 | 4 | |a Dairy Cattle |7 (dpeaa)DE-He213 | |
650 | 4 | |a Beef Cattle |7 (dpeaa)DE-He213 | |
650 | 4 | |a Cattle Breed |7 (dpeaa)DE-He213 | |
700 | 1 | |a Mohammadabadi, M. R. |4 aut | |
700 | 1 | |a Zarrigabayi, G. E. |4 aut | |
700 | 1 | |a Gharahedaghi, A. A. |4 aut | |
700 | 1 | |a Nassiry, M. R. |4 aut | |
700 | 1 | |a Javadmansh, A. |4 aut | |
700 | 1 | |a Asadzadeh, N. |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Russian journal of genetics |d Moscow : MAIK Nauka/Interperiodica Publ., 1996 |g 44(2008), 4 vom: Apr., Seite 495-497 |w (DE-627)324825641 |w (DE-600)2031145-X |x 1608-3369 |7 nnns |
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856 | 4 | 0 | |u https://dx.doi.org/10.1134/S1022795408040169 |z lizenzpflichtig |3 Volltext |
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912 | |a GBV_ILN_2025 | ||
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912 | |a GBV_ILN_2027 | ||
912 | |a GBV_ILN_2031 | ||
912 | |a GBV_ILN_2034 | ||
912 | |a GBV_ILN_2037 | ||
912 | |a GBV_ILN_2038 | ||
912 | |a GBV_ILN_2039 | ||
912 | |a GBV_ILN_2044 | ||
912 | |a GBV_ILN_2048 | ||
912 | |a GBV_ILN_2049 | ||
912 | |a GBV_ILN_2050 | ||
912 | |a GBV_ILN_2055 | ||
912 | |a GBV_ILN_2057 | ||
912 | |a GBV_ILN_2059 | ||
912 | |a GBV_ILN_2061 | ||
912 | |a GBV_ILN_2064 | ||
912 | |a GBV_ILN_2065 | ||
912 | |a GBV_ILN_2068 | ||
912 | |a GBV_ILN_2070 | ||
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912 | |a GBV_ILN_2113 | ||
912 | |a GBV_ILN_2116 | ||
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912 | |a GBV_ILN_2122 | ||
912 | |a GBV_ILN_2129 | ||
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912 | |a GBV_ILN_2147 | ||
912 | |a GBV_ILN_2148 | ||
912 | |a GBV_ILN_2152 | ||
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912 | |a GBV_ILN_2336 | ||
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2008 |
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10.1134/S1022795408040169 doi (DE-627)SPR017455901 (SPR)S1022795408040169-e DE-627 ger DE-627 rakwb eng Javanmard, A. verfasserin aut Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © MAIK Nauka 2008 Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. Hair Root (dpeaa)DE-He213 Feed Intake (dpeaa)DE-He213 Dairy Cattle (dpeaa)DE-He213 Beef Cattle (dpeaa)DE-He213 Cattle Breed (dpeaa)DE-He213 Mohammadabadi, M. R. aut Zarrigabayi, G. E. aut Gharahedaghi, A. A. aut Nassiry, M. R. aut Javadmansh, A. aut Asadzadeh, N. aut Enthalten in Russian journal of genetics Moscow : MAIK Nauka/Interperiodica Publ., 1996 44(2008), 4 vom: Apr., Seite 495-497 (DE-627)324825641 (DE-600)2031145-X 1608-3369 nnns volume:44 year:2008 number:4 month:04 pages:495-497 https://dx.doi.org/10.1134/S1022795408040169 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2008 4 04 495-497 |
spelling |
10.1134/S1022795408040169 doi (DE-627)SPR017455901 (SPR)S1022795408040169-e DE-627 ger DE-627 rakwb eng Javanmard, A. verfasserin aut Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © MAIK Nauka 2008 Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. Hair Root (dpeaa)DE-He213 Feed Intake (dpeaa)DE-He213 Dairy Cattle (dpeaa)DE-He213 Beef Cattle (dpeaa)DE-He213 Cattle Breed (dpeaa)DE-He213 Mohammadabadi, M. R. aut Zarrigabayi, G. E. aut Gharahedaghi, A. A. aut Nassiry, M. R. aut Javadmansh, A. aut Asadzadeh, N. aut Enthalten in Russian journal of genetics Moscow : MAIK Nauka/Interperiodica Publ., 1996 44(2008), 4 vom: Apr., Seite 495-497 (DE-627)324825641 (DE-600)2031145-X 1608-3369 nnns volume:44 year:2008 number:4 month:04 pages:495-497 https://dx.doi.org/10.1134/S1022795408040169 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2008 4 04 495-497 |
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10.1134/S1022795408040169 doi (DE-627)SPR017455901 (SPR)S1022795408040169-e DE-627 ger DE-627 rakwb eng Javanmard, A. verfasserin aut Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © MAIK Nauka 2008 Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. Hair Root (dpeaa)DE-He213 Feed Intake (dpeaa)DE-He213 Dairy Cattle (dpeaa)DE-He213 Beef Cattle (dpeaa)DE-He213 Cattle Breed (dpeaa)DE-He213 Mohammadabadi, M. R. aut Zarrigabayi, G. E. aut Gharahedaghi, A. A. aut Nassiry, M. R. aut Javadmansh, A. aut Asadzadeh, N. aut Enthalten in Russian journal of genetics Moscow : MAIK Nauka/Interperiodica Publ., 1996 44(2008), 4 vom: Apr., Seite 495-497 (DE-627)324825641 (DE-600)2031145-X 1608-3369 nnns volume:44 year:2008 number:4 month:04 pages:495-497 https://dx.doi.org/10.1134/S1022795408040169 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2008 4 04 495-497 |
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10.1134/S1022795408040169 doi (DE-627)SPR017455901 (SPR)S1022795408040169-e DE-627 ger DE-627 rakwb eng Javanmard, A. verfasserin aut Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © MAIK Nauka 2008 Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. Hair Root (dpeaa)DE-He213 Feed Intake (dpeaa)DE-He213 Dairy Cattle (dpeaa)DE-He213 Beef Cattle (dpeaa)DE-He213 Cattle Breed (dpeaa)DE-He213 Mohammadabadi, M. R. aut Zarrigabayi, G. E. aut Gharahedaghi, A. A. aut Nassiry, M. R. aut Javadmansh, A. aut Asadzadeh, N. aut Enthalten in Russian journal of genetics Moscow : MAIK Nauka/Interperiodica Publ., 1996 44(2008), 4 vom: Apr., Seite 495-497 (DE-627)324825641 (DE-600)2031145-X 1608-3369 nnns volume:44 year:2008 number:4 month:04 pages:495-497 https://dx.doi.org/10.1134/S1022795408040169 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2008 4 04 495-497 |
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10.1134/S1022795408040169 doi (DE-627)SPR017455901 (SPR)S1022795408040169-e DE-627 ger DE-627 rakwb eng Javanmard, A. verfasserin aut Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © MAIK Nauka 2008 Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. Hair Root (dpeaa)DE-He213 Feed Intake (dpeaa)DE-He213 Dairy Cattle (dpeaa)DE-He213 Beef Cattle (dpeaa)DE-He213 Cattle Breed (dpeaa)DE-He213 Mohammadabadi, M. R. aut Zarrigabayi, G. E. aut Gharahedaghi, A. A. aut Nassiry, M. R. aut Javadmansh, A. aut Asadzadeh, N. aut Enthalten in Russian journal of genetics Moscow : MAIK Nauka/Interperiodica Publ., 1996 44(2008), 4 vom: Apr., Seite 495-497 (DE-627)324825641 (DE-600)2031145-X 1608-3369 nnns volume:44 year:2008 number:4 month:04 pages:495-497 https://dx.doi.org/10.1134/S1022795408040169 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2008 4 04 495-497 |
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Javanmard, A. @@aut@@ Mohammadabadi, M. R. @@aut@@ Zarrigabayi, G. E. @@aut@@ Gharahedaghi, A. A. @@aut@@ Nassiry, M. R. @@aut@@ Javadmansh, A. @@aut@@ Asadzadeh, N. @@aut@@ |
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author |
Javanmard, A. |
spellingShingle |
Javanmard, A. misc Hair Root misc Feed Intake misc Dairy Cattle misc Beef Cattle misc Cattle Breed Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) |
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Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) Hair Root (dpeaa)DE-He213 Feed Intake (dpeaa)DE-He213 Dairy Cattle (dpeaa)DE-He213 Beef Cattle (dpeaa)DE-He213 Cattle Breed (dpeaa)DE-He213 |
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Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) |
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Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) |
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Javanmard, A. Mohammadabadi, M. R. Zarrigabayi, G. E. Gharahedaghi, A. A. Nassiry, M. R. Javadmansh, A. Asadzadeh, N. |
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polymorphism within the intron region of the bovine leptin gene in iranian sarabi cattle (iranian bos taurus) |
title_auth |
Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) |
abstract |
Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. © MAIK Nauka 2008 |
abstractGer |
Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. © MAIK Nauka 2008 |
abstract_unstemmed |
Abstract The main goal of breeders is breeding superior animals. Most traits of the economic importance in farm animals are determined by polygenic loci and environmental factors. Progress in animal breeding may be improved by combining traditional performance data with molecular genetic information on quantitative loci in selection index. Candidate genes are chosen for study on the basis of known relationships between biochemical and physiological processes. Leptin is 16 kDa protein that is synthesized by adipose tissue and it is involved in the regulation of feed intake, energy balance, fertility, and immune functions. In cattle, the leptin gene is located on chromosome 4. It consists of three exons and two introns, of which only two exons are translated into protein. Sixty-six animals were genotyped for this project. PCR was carried out between exon 2 (intron 2). A strategy employing polymerase chain reaction was used to amplify a 422 bp from blood, semen, hair root, and milk DNA. Digestion of polymerase chain reaction products with Sau3AI revealed two alleles: allele A was 390, 32 fragments and allele B was 303, 88, 32 (only 303 fragment visible on the gel). Three patterns were observed and frequencies were 0.31, 0.43, and 0.14 for AA, AB and BB, respectively. This polymorphism could be further evaluated for marker-assisted selection and developed PCR methodology would expedite screening for large numbers of animals required for such studies. © MAIK Nauka 2008 |
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title_short |
Polymorphism within the intron region of the bovine leptin gene in Iranian Sarabi cattle (Iranian Bos taurus) |
url |
https://dx.doi.org/10.1134/S1022795408040169 |
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Mohammadabadi, M. R. Zarrigabayi, G. E. Gharahedaghi, A. A. Nassiry, M. R. Javadmansh, A. Asadzadeh, N. |
author2Str |
Mohammadabadi, M. R. Zarrigabayi, G. E. Gharahedaghi, A. A. Nassiry, M. R. Javadmansh, A. Asadzadeh, N. |
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up_date |
2024-07-04T03:25:30.056Z |
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|
score |
7.399638 |