Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio
Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was...
Ausführliche Beschreibung
Autor*in: |
Yi, Jianhong [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2010 |
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Schlagwörter: |
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Anmerkung: |
© Pleiades Publishing, Ltd. 2010 |
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Übergeordnetes Werk: |
Enthalten in: Polymer science - Moscow : MAIK Nauka/Interperiodics Publ., 2006, 52(2010), 1-2 vom: Feb., Seite 35-40 |
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Übergeordnetes Werk: |
volume:52 ; year:2010 ; number:1-2 ; month:02 ; pages:35-40 |
Links: |
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DOI / URN: |
10.1134/S1560090410010057 |
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Katalog-ID: |
SPR020251785 |
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520 | |a Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. | ||
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700 | 1 | |a Hu, Guosheng |4 aut | |
700 | 1 | |a Wang, Biaobing |4 aut | |
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10.1134/S1560090410010057 doi (DE-627)SPR020251785 (SPR)S1560090410010057-e DE-627 ger DE-627 rakwb eng Yi, Jianhong verfasserin aut Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Pleiades Publishing, Ltd. 2010 Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. Polymer Science Series (dpeaa)DE-He213 Graft Copolymer (dpeaa)DE-He213 AMPHIPHILIC Copolymer (dpeaa)DE-He213 PBLG (dpeaa)DE-He213 Molar Feed Ratio (dpeaa)DE-He213 Zhou, Xiumiao aut Hu, Guosheng aut Wang, Biaobing aut Enthalten in Polymer science Moscow : MAIK Nauka/Interperiodics Publ., 2006 52(2010), 1-2 vom: Feb., Seite 35-40 (DE-627)513506896 (DE-600)2239942-2 1555-6123 nnns volume:52 year:2010 number:1-2 month:02 pages:35-40 https://dx.doi.org/10.1134/S1560090410010057 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 52 2010 1-2 02 35-40 |
spelling |
10.1134/S1560090410010057 doi (DE-627)SPR020251785 (SPR)S1560090410010057-e DE-627 ger DE-627 rakwb eng Yi, Jianhong verfasserin aut Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Pleiades Publishing, Ltd. 2010 Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. Polymer Science Series (dpeaa)DE-He213 Graft Copolymer (dpeaa)DE-He213 AMPHIPHILIC Copolymer (dpeaa)DE-He213 PBLG (dpeaa)DE-He213 Molar Feed Ratio (dpeaa)DE-He213 Zhou, Xiumiao aut Hu, Guosheng aut Wang, Biaobing aut Enthalten in Polymer science Moscow : MAIK Nauka/Interperiodics Publ., 2006 52(2010), 1-2 vom: Feb., Seite 35-40 (DE-627)513506896 (DE-600)2239942-2 1555-6123 nnns volume:52 year:2010 number:1-2 month:02 pages:35-40 https://dx.doi.org/10.1134/S1560090410010057 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 52 2010 1-2 02 35-40 |
allfields_unstemmed |
10.1134/S1560090410010057 doi (DE-627)SPR020251785 (SPR)S1560090410010057-e DE-627 ger DE-627 rakwb eng Yi, Jianhong verfasserin aut Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Pleiades Publishing, Ltd. 2010 Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. Polymer Science Series (dpeaa)DE-He213 Graft Copolymer (dpeaa)DE-He213 AMPHIPHILIC Copolymer (dpeaa)DE-He213 PBLG (dpeaa)DE-He213 Molar Feed Ratio (dpeaa)DE-He213 Zhou, Xiumiao aut Hu, Guosheng aut Wang, Biaobing aut Enthalten in Polymer science Moscow : MAIK Nauka/Interperiodics Publ., 2006 52(2010), 1-2 vom: Feb., Seite 35-40 (DE-627)513506896 (DE-600)2239942-2 1555-6123 nnns volume:52 year:2010 number:1-2 month:02 pages:35-40 https://dx.doi.org/10.1134/S1560090410010057 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 52 2010 1-2 02 35-40 |
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10.1134/S1560090410010057 doi (DE-627)SPR020251785 (SPR)S1560090410010057-e DE-627 ger DE-627 rakwb eng Yi, Jianhong verfasserin aut Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Pleiades Publishing, Ltd. 2010 Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. Polymer Science Series (dpeaa)DE-He213 Graft Copolymer (dpeaa)DE-He213 AMPHIPHILIC Copolymer (dpeaa)DE-He213 PBLG (dpeaa)DE-He213 Molar Feed Ratio (dpeaa)DE-He213 Zhou, Xiumiao aut Hu, Guosheng aut Wang, Biaobing aut Enthalten in Polymer science Moscow : MAIK Nauka/Interperiodics Publ., 2006 52(2010), 1-2 vom: Feb., Seite 35-40 (DE-627)513506896 (DE-600)2239942-2 1555-6123 nnns volume:52 year:2010 number:1-2 month:02 pages:35-40 https://dx.doi.org/10.1134/S1560090410010057 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 52 2010 1-2 02 35-40 |
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10.1134/S1560090410010057 doi (DE-627)SPR020251785 (SPR)S1560090410010057-e DE-627 ger DE-627 rakwb eng Yi, Jianhong verfasserin aut Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Pleiades Publishing, Ltd. 2010 Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. Polymer Science Series (dpeaa)DE-He213 Graft Copolymer (dpeaa)DE-He213 AMPHIPHILIC Copolymer (dpeaa)DE-He213 PBLG (dpeaa)DE-He213 Molar Feed Ratio (dpeaa)DE-He213 Zhou, Xiumiao aut Hu, Guosheng aut Wang, Biaobing aut Enthalten in Polymer science Moscow : MAIK Nauka/Interperiodics Publ., 2006 52(2010), 1-2 vom: Feb., Seite 35-40 (DE-627)513506896 (DE-600)2239942-2 1555-6123 nnns volume:52 year:2010 number:1-2 month:02 pages:35-40 https://dx.doi.org/10.1134/S1560090410010057 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 52 2010 1-2 02 35-40 |
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Enthalten in Polymer science 52(2010), 1-2 vom: Feb., Seite 35-40 volume:52 year:2010 number:1-2 month:02 pages:35-40 |
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Yi, Jianhong @@aut@@ Zhou, Xiumiao @@aut@@ Hu, Guosheng @@aut@@ Wang, Biaobing @@aut@@ |
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author |
Yi, Jianhong |
spellingShingle |
Yi, Jianhong misc Polymer Science Series misc Graft Copolymer misc AMPHIPHILIC Copolymer misc PBLG misc Molar Feed Ratio Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio |
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Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio Polymer Science Series (dpeaa)DE-He213 Graft Copolymer (dpeaa)DE-He213 AMPHIPHILIC Copolymer (dpeaa)DE-He213 PBLG (dpeaa)DE-He213 Molar Feed Ratio (dpeaa)DE-He213 |
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misc Polymer Science Series misc Graft Copolymer misc AMPHIPHILIC Copolymer misc PBLG misc Molar Feed Ratio |
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misc Polymer Science Series misc Graft Copolymer misc AMPHIPHILIC Copolymer misc PBLG misc Molar Feed Ratio |
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misc Polymer Science Series misc Graft Copolymer misc AMPHIPHILIC Copolymer misc PBLG misc Molar Feed Ratio |
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Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio |
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Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio |
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Yi, Jianhong |
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10.1134/S1560090410010057 |
title_sort |
preparation of the amphiphilic copolymer of poly(γ-benzyl l-glutamate)-g-poly(ethylene glycol) with different grafting ratio |
title_auth |
Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio |
abstract |
Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. © Pleiades Publishing, Ltd. 2010 |
abstractGer |
Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. © Pleiades Publishing, Ltd. 2010 |
abstract_unstemmed |
Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio. © Pleiades Publishing, Ltd. 2010 |
collection_details |
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container_issue |
1-2 |
title_short |
Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio |
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https://dx.doi.org/10.1134/S1560090410010057 |
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Zhou, Xiumiao Hu, Guosheng Wang, Biaobing |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR020251785</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519201920.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201006s2010 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1134/S1560090410010057</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR020251785</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)S1560090410010057-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Yi, Jianhong</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Preparation of the amphiphilic copolymer of poly(γ-benzyl L-glutamate)-g-poly(ethylene glycol) with different grafting ratio</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2010</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Pleiades Publishing, Ltd. 2010</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Poly(γ-benzyl L-glutamate)- g-poly(ethylene glycol) (PBLG-g- PEG) with different grafting ratio was prepared using P-toluenesulfonic acid as catalyst. The effect of the molecular weight of mono- methyl oligo(ethylene glycol), the molar feed ratio and reaction time on the grafting ratio was investigated. The micelles of PBLG-g-PEG were prepared by the dialysis method in deionized water. Transmission electron microscopy and dynamic light scatter studies showed that the micelles exhibited spherical morphologies and the diameter of the micelles was in the range of 50–200 nm. Clonazepam was loaded onto the core part of the micelles and drug-loading content and rele ase rate were dependent on the grafting ratio.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Polymer Science Series</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Graft Copolymer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">AMPHIPHILIC Copolymer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">PBLG</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Molar Feed Ratio</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhou, Xiumiao</subfield><subfield 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