Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans
Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Com...
Ausführliche Beschreibung
Autor*in: |
Li, Yong-Hong [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2011 |
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Anmerkung: |
© CARS 2011 |
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Übergeordnetes Werk: |
Enthalten in: International journal of computer assisted radiology and surgery - Berlin : Springer, 2006, 7(2011), 4 vom: 12. Nov., Seite 507-516 |
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Übergeordnetes Werk: |
volume:7 ; year:2011 ; number:4 ; day:12 ; month:11 ; pages:507-516 |
Links: |
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DOI / URN: |
10.1007/s11548-011-0664-3 |
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Katalog-ID: |
SPR020700687 |
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245 | 1 | 0 | |a Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans |
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520 | |a Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. | ||
650 | 4 | |a Subarachnoid space |7 (dpeaa)DE-He213 | |
650 | 4 | |a Cerebrospinal fluid |7 (dpeaa)DE-He213 | |
650 | 4 | |a Computer-aided diagnosis |7 (dpeaa)DE-He213 | |
650 | 4 | |a Kernel density estimation |7 (dpeaa)DE-He213 | |
700 | 1 | |a Zhang, Liang |4 aut | |
700 | 1 | |a Hu, Qing-Mao |4 aut | |
700 | 1 | |a Li, Hong-Wei |4 aut | |
700 | 1 | |a Jia, Fu-Cang |4 aut | |
700 | 1 | |a Wu, Jian-Huang |4 aut | |
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10.1007/s11548-011-0664-3 doi (DE-627)SPR020700687 (SPR)s11548-011-0664-3-e DE-627 ger DE-627 rakwb eng Li, Yong-Hong verfasserin aut Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © CARS 2011 Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. Subarachnoid space (dpeaa)DE-He213 Cerebrospinal fluid (dpeaa)DE-He213 Computer-aided diagnosis (dpeaa)DE-He213 Kernel density estimation (dpeaa)DE-He213 Zhang, Liang aut Hu, Qing-Mao aut Li, Hong-Wei aut Jia, Fu-Cang aut Wu, Jian-Huang aut Enthalten in International journal of computer assisted radiology and surgery Berlin : Springer, 2006 7(2011), 4 vom: 12. Nov., Seite 507-516 (DE-627)512299250 (DE-600)2235881-X 1861-6429 nnns volume:7 year:2011 number:4 day:12 month:11 pages:507-516 https://dx.doi.org/10.1007/s11548-011-0664-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2011 4 12 11 507-516 |
spelling |
10.1007/s11548-011-0664-3 doi (DE-627)SPR020700687 (SPR)s11548-011-0664-3-e DE-627 ger DE-627 rakwb eng Li, Yong-Hong verfasserin aut Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © CARS 2011 Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. Subarachnoid space (dpeaa)DE-He213 Cerebrospinal fluid (dpeaa)DE-He213 Computer-aided diagnosis (dpeaa)DE-He213 Kernel density estimation (dpeaa)DE-He213 Zhang, Liang aut Hu, Qing-Mao aut Li, Hong-Wei aut Jia, Fu-Cang aut Wu, Jian-Huang aut Enthalten in International journal of computer assisted radiology and surgery Berlin : Springer, 2006 7(2011), 4 vom: 12. Nov., Seite 507-516 (DE-627)512299250 (DE-600)2235881-X 1861-6429 nnns volume:7 year:2011 number:4 day:12 month:11 pages:507-516 https://dx.doi.org/10.1007/s11548-011-0664-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2011 4 12 11 507-516 |
allfields_unstemmed |
10.1007/s11548-011-0664-3 doi (DE-627)SPR020700687 (SPR)s11548-011-0664-3-e DE-627 ger DE-627 rakwb eng Li, Yong-Hong verfasserin aut Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © CARS 2011 Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. Subarachnoid space (dpeaa)DE-He213 Cerebrospinal fluid (dpeaa)DE-He213 Computer-aided diagnosis (dpeaa)DE-He213 Kernel density estimation (dpeaa)DE-He213 Zhang, Liang aut Hu, Qing-Mao aut Li, Hong-Wei aut Jia, Fu-Cang aut Wu, Jian-Huang aut Enthalten in International journal of computer assisted radiology and surgery Berlin : Springer, 2006 7(2011), 4 vom: 12. Nov., Seite 507-516 (DE-627)512299250 (DE-600)2235881-X 1861-6429 nnns volume:7 year:2011 number:4 day:12 month:11 pages:507-516 https://dx.doi.org/10.1007/s11548-011-0664-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2011 4 12 11 507-516 |
allfieldsGer |
10.1007/s11548-011-0664-3 doi (DE-627)SPR020700687 (SPR)s11548-011-0664-3-e DE-627 ger DE-627 rakwb eng Li, Yong-Hong verfasserin aut Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © CARS 2011 Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. Subarachnoid space (dpeaa)DE-He213 Cerebrospinal fluid (dpeaa)DE-He213 Computer-aided diagnosis (dpeaa)DE-He213 Kernel density estimation (dpeaa)DE-He213 Zhang, Liang aut Hu, Qing-Mao aut Li, Hong-Wei aut Jia, Fu-Cang aut Wu, Jian-Huang aut Enthalten in International journal of computer assisted radiology and surgery Berlin : Springer, 2006 7(2011), 4 vom: 12. Nov., Seite 507-516 (DE-627)512299250 (DE-600)2235881-X 1861-6429 nnns volume:7 year:2011 number:4 day:12 month:11 pages:507-516 https://dx.doi.org/10.1007/s11548-011-0664-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2011 4 12 11 507-516 |
allfieldsSound |
10.1007/s11548-011-0664-3 doi (DE-627)SPR020700687 (SPR)s11548-011-0664-3-e DE-627 ger DE-627 rakwb eng Li, Yong-Hong verfasserin aut Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © CARS 2011 Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. Subarachnoid space (dpeaa)DE-He213 Cerebrospinal fluid (dpeaa)DE-He213 Computer-aided diagnosis (dpeaa)DE-He213 Kernel density estimation (dpeaa)DE-He213 Zhang, Liang aut Hu, Qing-Mao aut Li, Hong-Wei aut Jia, Fu-Cang aut Wu, Jian-Huang aut Enthalten in International journal of computer assisted radiology and surgery Berlin : Springer, 2006 7(2011), 4 vom: 12. Nov., Seite 507-516 (DE-627)512299250 (DE-600)2235881-X 1861-6429 nnns volume:7 year:2011 number:4 day:12 month:11 pages:507-516 https://dx.doi.org/10.1007/s11548-011-0664-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2011 4 12 11 507-516 |
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Enthalten in International journal of computer assisted radiology and surgery 7(2011), 4 vom: 12. Nov., Seite 507-516 volume:7 year:2011 number:4 day:12 month:11 pages:507-516 |
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Enthalten in International journal of computer assisted radiology and surgery 7(2011), 4 vom: 12. Nov., Seite 507-516 volume:7 year:2011 number:4 day:12 month:11 pages:507-516 |
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Subarachnoid space Cerebrospinal fluid Computer-aided diagnosis Kernel density estimation |
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International journal of computer assisted radiology and surgery |
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Li, Yong-Hong @@aut@@ Zhang, Liang @@aut@@ Hu, Qing-Mao @@aut@@ Li, Hong-Wei @@aut@@ Jia, Fu-Cang @@aut@@ Wu, Jian-Huang @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR020700687</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519153353.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201006s2011 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s11548-011-0664-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR020700687</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s11548-011-0664-3-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Li, Yong-Hong</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2011</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© CARS 2011</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Subarachnoid space</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cerebrospinal fluid</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Computer-aided diagnosis</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Kernel density estimation</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhang, Liang</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hu, Qing-Mao</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Hong-Wei</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jia, Fu-Cang</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wu, Jian-Huang</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">International journal of computer assisted radiology and surgery</subfield><subfield code="d">Berlin : Springer, 2006</subfield><subfield code="g">7(2011), 4 vom: 12. 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|
author |
Li, Yong-Hong |
spellingShingle |
Li, Yong-Hong misc Subarachnoid space misc Cerebrospinal fluid misc Computer-aided diagnosis misc Kernel density estimation Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans |
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Li, Yong-Hong |
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Not Illustrated |
issn |
1861-6429 |
topic_title |
Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans Subarachnoid space (dpeaa)DE-He213 Cerebrospinal fluid (dpeaa)DE-He213 Computer-aided diagnosis (dpeaa)DE-He213 Kernel density estimation (dpeaa)DE-He213 |
topic |
misc Subarachnoid space misc Cerebrospinal fluid misc Computer-aided diagnosis misc Kernel density estimation |
topic_unstemmed |
misc Subarachnoid space misc Cerebrospinal fluid misc Computer-aided diagnosis misc Kernel density estimation |
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misc Subarachnoid space misc Cerebrospinal fluid misc Computer-aided diagnosis misc Kernel density estimation |
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Elektronische Aufsätze Aufsätze Elektronische Ressource |
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International journal of computer assisted radiology and surgery |
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International journal of computer assisted radiology and surgery |
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Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans |
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(DE-627)SPR020700687 (SPR)s11548-011-0664-3-e |
title_full |
Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans |
author_sort |
Li, Yong-Hong |
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International journal of computer assisted radiology and surgery |
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International journal of computer assisted radiology and surgery |
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eng |
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2011 |
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Li, Yong-Hong Zhang, Liang Hu, Qing-Mao Li, Hong-Wei Jia, Fu-Cang Wu, Jian-Huang |
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7 |
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Elektronische Aufsätze |
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Li, Yong-Hong |
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10.1007/s11548-011-0664-3 |
title_sort |
automatic subarachnoid space segmentation and hemorrhage detection in clinical head ct scans |
title_auth |
Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans |
abstract |
Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. © CARS 2011 |
abstractGer |
Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. © CARS 2011 |
abstract_unstemmed |
Purpose The subarachnoid space (SAS) lies between the arachnoid membrane and the pia mater of the human brain, normally filled with cerebrospinal fluid (CSF). Subarachnoid hemorrhage (SAH) is a serious complication of neurological disease that can have high mortality and high risk of disability. Computed tomography (CT) head scans are often used for diagnosing SAH which may be difficult when the hemorrhage is small or subtle. A computer-aided diagnosis system from CT images is thus developed to augment image interpretation. Methods Supervised learning using the probability of distance features of several landmarks was employed to recognize SAS. For each CT image, the SAS was approximated in four steps: (1) Landmarks including brain boundary, midsagittal plane (MSP), anterior and posterior intersection points of brain boundary with the MSP, and superior point of the brain were extracted. (2) Distances to all the landmarks were calculated for every pixel in the CT image, and combined to construct a high-dimensional feature vector. (3) Using head CT images with manually delineated SAS as training dataset, the prior probabilities of distances for pixels within SAS and non-SAS were computed. (4) Any pixel of a head CT scan in the testing dataset was classified as an SAS or non-SAS pixel in a Bayesian decision framework based on its distance features. Results The proposed method was validated on clinical head CT images by comparison with manual segmentation. The results showed that the automated method is consistent with the gold standard. Compared with elastic registration based on grayscale information, the proposed method was less affected by grayscale variation between normal controls and patients. Compared with manual delineation, the average spatial overlap, relative overlap, and similarity index were, respectively, 89, 63, and 76% for the automatic SAS approximation of the 69 head CT scans tested. The proposed method was tested for SAH detection and yielded a sensitivity of 100% and a specificity of 92%. Conclusion Automated SAH detection with high sensitivity was shown feasible in a prototype computer-aided diagnosis system. The proposed method may be extended for computer-aided diagnosis of several CSF-related diseases relevant to SAS abnormalities. © CARS 2011 |
collection_details |
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container_issue |
4 |
title_short |
Automatic subarachnoid space segmentation and hemorrhage detection in clinical head CT scans |
url |
https://dx.doi.org/10.1007/s11548-011-0664-3 |
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true |
author2 |
Zhang, Liang Hu, Qing-Mao Li, Hong-Wei Jia, Fu-Cang Wu, Jian-Huang |
author2Str |
Zhang, Liang Hu, Qing-Mao Li, Hong-Wei Jia, Fu-Cang Wu, Jian-Huang |
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doi_str |
10.1007/s11548-011-0664-3 |
up_date |
2024-07-03T17:41:50.594Z |
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|
score |
7.399701 |