Diagnostic significance of anti-annexin-A5 antibody determination

Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Baleva, Marta P. [verfasserIn] Hristova, Maria H. Nikolov, Krasimir V.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Schlagwörter:	Anti-annexin A5 antibodies Antiphospholipid syndrome Pregnancy loss Systemic lupus erythematosus

Anmerkung:	© © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009

Übergeordnetes Werk:	Enthalten in: Central European journal of medicine - Warsaw : Central European Science Journals, 2006, 5(2009), 1 vom: 07. Dez., Seite 6-11
Übergeordnetes Werk:	volume:5 ; year:2009 ; number:1 ; day:07 ; month:12 ; pages:6-11

Links:	Volltext

DOI / URN:	10.2478/s11536-009-0132-4

Katalog-ID:	SPR020871759

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520			\|a Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance.
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spelling	10.2478/s11536-009-0132-4 doi (DE-627)SPR020871759 (SPR)s11536-009-0132-4-e DE-627 ger DE-627 rakwb eng Baleva, Marta P. verfasserin aut Diagnostic significance of anti-annexin-A5 antibody determination 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009 Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. Anti-annexin A5 antibodies (dpeaa)DE-He213 Antiphospholipid syndrome (dpeaa)DE-He213 Pregnancy loss (dpeaa)DE-He213 Systemic lupus erythematosus (dpeaa)DE-He213 Hristova, Maria H. aut Nikolov, Krasimir V. aut Enthalten in Central European journal of medicine Warsaw : Central European Science Journals, 2006 5(2009), 1 vom: 07. Dez., Seite 6-11 (DE-627)511914962 (DE-600)2234698-3 1644-3640 nnns volume:5 year:2009 number:1 day:07 month:12 pages:6-11 https://dx.doi.org/10.2478/s11536-009-0132-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 1 07 12 6-11
allfields_unstemmed	10.2478/s11536-009-0132-4 doi (DE-627)SPR020871759 (SPR)s11536-009-0132-4-e DE-627 ger DE-627 rakwb eng Baleva, Marta P. verfasserin aut Diagnostic significance of anti-annexin-A5 antibody determination 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009 Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. Anti-annexin A5 antibodies (dpeaa)DE-He213 Antiphospholipid syndrome (dpeaa)DE-He213 Pregnancy loss (dpeaa)DE-He213 Systemic lupus erythematosus (dpeaa)DE-He213 Hristova, Maria H. aut Nikolov, Krasimir V. aut Enthalten in Central European journal of medicine Warsaw : Central European Science Journals, 2006 5(2009), 1 vom: 07. Dez., Seite 6-11 (DE-627)511914962 (DE-600)2234698-3 1644-3640 nnns volume:5 year:2009 number:1 day:07 month:12 pages:6-11 https://dx.doi.org/10.2478/s11536-009-0132-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 1 07 12 6-11
allfieldsGer	10.2478/s11536-009-0132-4 doi (DE-627)SPR020871759 (SPR)s11536-009-0132-4-e DE-627 ger DE-627 rakwb eng Baleva, Marta P. verfasserin aut Diagnostic significance of anti-annexin-A5 antibody determination 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009 Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. Anti-annexin A5 antibodies (dpeaa)DE-He213 Antiphospholipid syndrome (dpeaa)DE-He213 Pregnancy loss (dpeaa)DE-He213 Systemic lupus erythematosus (dpeaa)DE-He213 Hristova, Maria H. aut Nikolov, Krasimir V. aut Enthalten in Central European journal of medicine Warsaw : Central European Science Journals, 2006 5(2009), 1 vom: 07. Dez., Seite 6-11 (DE-627)511914962 (DE-600)2234698-3 1644-3640 nnns volume:5 year:2009 number:1 day:07 month:12 pages:6-11 https://dx.doi.org/10.2478/s11536-009-0132-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 1 07 12 6-11
allfieldsSound	10.2478/s11536-009-0132-4 doi (DE-627)SPR020871759 (SPR)s11536-009-0132-4-e DE-627 ger DE-627 rakwb eng Baleva, Marta P. verfasserin aut Diagnostic significance of anti-annexin-A5 antibody determination 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009 Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. Anti-annexin A5 antibodies (dpeaa)DE-He213 Antiphospholipid syndrome (dpeaa)DE-He213 Pregnancy loss (dpeaa)DE-He213 Systemic lupus erythematosus (dpeaa)DE-He213 Hristova, Maria H. aut Nikolov, Krasimir V. aut Enthalten in Central European journal of medicine Warsaw : Central European Science Journals, 2006 5(2009), 1 vom: 07. Dez., Seite 6-11 (DE-627)511914962 (DE-600)2234698-3 1644-3640 nnns volume:5 year:2009 number:1 day:07 month:12 pages:6-11 https://dx.doi.org/10.2478/s11536-009-0132-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 1 07 12 6-11
language	English
source	Enthalten in Central European journal of medicine 5(2009), 1 vom: 07. Dez., Seite 6-11 volume:5 year:2009 number:1 day:07 month:12 pages:6-11
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topic_facet	Anti-annexin A5 antibodies Antiphospholipid syndrome Pregnancy loss Systemic lupus erythematosus
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authorswithroles_txt_mv	Baleva, Marta P. @@aut@@ Hristova, Maria H. @@aut@@ Nikolov, Krasimir V. @@aut@@
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author	Baleva, Marta P.
spellingShingle	Baleva, Marta P. misc Anti-annexin A5 antibodies misc Antiphospholipid syndrome misc Pregnancy loss misc Systemic lupus erythematosus Diagnostic significance of anti-annexin-A5 antibody determination
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topic_title	Diagnostic significance of anti-annexin-A5 antibody determination Anti-annexin A5 antibodies (dpeaa)DE-He213 Antiphospholipid syndrome (dpeaa)DE-He213 Pregnancy loss (dpeaa)DE-He213 Systemic lupus erythematosus (dpeaa)DE-He213
topic	misc Anti-annexin A5 antibodies misc Antiphospholipid syndrome misc Pregnancy loss misc Systemic lupus erythematosus
topic_unstemmed	misc Anti-annexin A5 antibodies misc Antiphospholipid syndrome misc Pregnancy loss misc Systemic lupus erythematosus
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title	Diagnostic significance of anti-annexin-A5 antibody determination
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title_full	Diagnostic significance of anti-annexin-A5 antibody determination
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title_sort	diagnostic significance of anti-annexin-a5 antibody determination
title_auth	Diagnostic significance of anti-annexin-A5 antibody determination
abstract	Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009
abstractGer	Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009
abstract_unstemmed	Abstract Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible interpretation of the results is given. The authors suggest the significance of anti-annexin A5 antibodies as an additional diagnostic marker and discuss the necessity of more extensive research on their clinical significance. © © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009
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title_short	Diagnostic significance of anti-annexin-A5 antibody determination
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Diagnostic significance of anti-annexin-A5 antibody determination

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