$ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project
Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men a...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sciacqua, Angela [verfasserIn] Perticone, Maria [verfasserIn] Tripepi, Giovanni [verfasserIn] Tassone, Eliezer J. [verfasserIn] Cimellaro, Antonio [verfasserIn] Mazzaferro, Deborah [verfasserIn] Sesti, Giorgio [verfasserIn] Perticone, Francesco [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Internal and emergency medicine - Milan : Springer Milan, 2006, 10(2015), 7 vom: 05. Mai, Seite 815-821 |
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| Übergeordnetes Werk: |
volume:10 ; year:2015 ; number:7 ; day:05 ; month:05 ; pages:815-821 |
| Links: |
|---|
| DOI / URN: |
10.1007/s11739-015-1243-3 |
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| Katalog-ID: |
SPR022126457 |
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| 245 | 1 | 0 | |a $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project |
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| 520 | |a Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. | ||
| 650 | 4 | |a Atrial fibrillation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a CHADS |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a score |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a CHA |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a DS |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a -VASc score |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cardiovascular risk factors |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Perticone, Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Tripepi, Giovanni |e verfasserin |4 aut | |
| 700 | 1 | |a Tassone, Eliezer J. |e verfasserin |4 aut | |
| 700 | 1 | |a Cimellaro, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a Mazzaferro, Deborah |e verfasserin |4 aut | |
| 700 | 1 | |a Sesti, Giorgio |e verfasserin |4 aut | |
| 700 | 1 | |a Perticone, Francesco |e verfasserin |4 aut | |
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10.1007/s11739-015-1243-3 doi (DE-627)SPR022126457 (SPR)s11739-015-1243-3-e DE-627 ger DE-627 rakwb eng 610 ASE 44.80 bkl Sciacqua, Angela verfasserin aut $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. Atrial fibrillation (dpeaa)DE-He213 CHADS (dpeaa)DE-He213 score (dpeaa)DE-He213 CHA (dpeaa)DE-He213 DS (dpeaa)DE-He213 -VASc score (dpeaa)DE-He213 Cardiovascular risk factors (dpeaa)DE-He213 Perticone, Maria verfasserin aut Tripepi, Giovanni verfasserin aut Tassone, Eliezer J. verfasserin aut Cimellaro, Antonio verfasserin aut Mazzaferro, Deborah verfasserin aut Sesti, Giorgio verfasserin aut Perticone, Francesco verfasserin aut Enthalten in Internal and emergency medicine Milan : Springer Milan, 2006 10(2015), 7 vom: 05. Mai, Seite 815-821 (DE-627)538216425 (DE-600)2378342-4 1970-9366 nnns volume:10 year:2015 number:7 day:05 month:05 pages:815-821 https://dx.doi.org/10.1007/s11739-015-1243-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.80 ASE AR 10 2015 7 05 05 815-821 |
| spelling |
10.1007/s11739-015-1243-3 doi (DE-627)SPR022126457 (SPR)s11739-015-1243-3-e DE-627 ger DE-627 rakwb eng 610 ASE 44.80 bkl Sciacqua, Angela verfasserin aut $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. Atrial fibrillation (dpeaa)DE-He213 CHADS (dpeaa)DE-He213 score (dpeaa)DE-He213 CHA (dpeaa)DE-He213 DS (dpeaa)DE-He213 -VASc score (dpeaa)DE-He213 Cardiovascular risk factors (dpeaa)DE-He213 Perticone, Maria verfasserin aut Tripepi, Giovanni verfasserin aut Tassone, Eliezer J. verfasserin aut Cimellaro, Antonio verfasserin aut Mazzaferro, Deborah verfasserin aut Sesti, Giorgio verfasserin aut Perticone, Francesco verfasserin aut Enthalten in Internal and emergency medicine Milan : Springer Milan, 2006 10(2015), 7 vom: 05. Mai, Seite 815-821 (DE-627)538216425 (DE-600)2378342-4 1970-9366 nnns volume:10 year:2015 number:7 day:05 month:05 pages:815-821 https://dx.doi.org/10.1007/s11739-015-1243-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.80 ASE AR 10 2015 7 05 05 815-821 |
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10.1007/s11739-015-1243-3 doi (DE-627)SPR022126457 (SPR)s11739-015-1243-3-e DE-627 ger DE-627 rakwb eng 610 ASE 44.80 bkl Sciacqua, Angela verfasserin aut $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. Atrial fibrillation (dpeaa)DE-He213 CHADS (dpeaa)DE-He213 score (dpeaa)DE-He213 CHA (dpeaa)DE-He213 DS (dpeaa)DE-He213 -VASc score (dpeaa)DE-He213 Cardiovascular risk factors (dpeaa)DE-He213 Perticone, Maria verfasserin aut Tripepi, Giovanni verfasserin aut Tassone, Eliezer J. verfasserin aut Cimellaro, Antonio verfasserin aut Mazzaferro, Deborah verfasserin aut Sesti, Giorgio verfasserin aut Perticone, Francesco verfasserin aut Enthalten in Internal and emergency medicine Milan : Springer Milan, 2006 10(2015), 7 vom: 05. Mai, Seite 815-821 (DE-627)538216425 (DE-600)2378342-4 1970-9366 nnns volume:10 year:2015 number:7 day:05 month:05 pages:815-821 https://dx.doi.org/10.1007/s11739-015-1243-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.80 ASE AR 10 2015 7 05 05 815-821 |
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10.1007/s11739-015-1243-3 doi (DE-627)SPR022126457 (SPR)s11739-015-1243-3-e DE-627 ger DE-627 rakwb eng 610 ASE 44.80 bkl Sciacqua, Angela verfasserin aut $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. Atrial fibrillation (dpeaa)DE-He213 CHADS (dpeaa)DE-He213 score (dpeaa)DE-He213 CHA (dpeaa)DE-He213 DS (dpeaa)DE-He213 -VASc score (dpeaa)DE-He213 Cardiovascular risk factors (dpeaa)DE-He213 Perticone, Maria verfasserin aut Tripepi, Giovanni verfasserin aut Tassone, Eliezer J. verfasserin aut Cimellaro, Antonio verfasserin aut Mazzaferro, Deborah verfasserin aut Sesti, Giorgio verfasserin aut Perticone, Francesco verfasserin aut Enthalten in Internal and emergency medicine Milan : Springer Milan, 2006 10(2015), 7 vom: 05. Mai, Seite 815-821 (DE-627)538216425 (DE-600)2378342-4 1970-9366 nnns volume:10 year:2015 number:7 day:05 month:05 pages:815-821 https://dx.doi.org/10.1007/s11739-015-1243-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.80 ASE AR 10 2015 7 05 05 815-821 |
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10.1007/s11739-015-1243-3 doi (DE-627)SPR022126457 (SPR)s11739-015-1243-3-e DE-627 ger DE-627 rakwb eng 610 ASE 44.80 bkl Sciacqua, Angela verfasserin aut $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. Atrial fibrillation (dpeaa)DE-He213 CHADS (dpeaa)DE-He213 score (dpeaa)DE-He213 CHA (dpeaa)DE-He213 DS (dpeaa)DE-He213 -VASc score (dpeaa)DE-He213 Cardiovascular risk factors (dpeaa)DE-He213 Perticone, Maria verfasserin aut Tripepi, Giovanni verfasserin aut Tassone, Eliezer J. verfasserin aut Cimellaro, Antonio verfasserin aut Mazzaferro, Deborah verfasserin aut Sesti, Giorgio verfasserin aut Perticone, Francesco verfasserin aut Enthalten in Internal and emergency medicine Milan : Springer Milan, 2006 10(2015), 7 vom: 05. Mai, Seite 815-821 (DE-627)538216425 (DE-600)2378342-4 1970-9366 nnns volume:10 year:2015 number:7 day:05 month:05 pages:815-821 https://dx.doi.org/10.1007/s11739-015-1243-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.80 ASE AR 10 2015 7 05 05 815-821 |
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Enthalten in Internal and emergency medicine 10(2015), 7 vom: 05. Mai, Seite 815-821 volume:10 year:2015 number:7 day:05 month:05 pages:815-821 |
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Enthalten in Internal and emergency medicine 10(2015), 7 vom: 05. Mai, Seite 815-821 volume:10 year:2015 number:7 day:05 month:05 pages:815-821 |
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Atrial fibrillation CHADS score CHA DS -VASc score Cardiovascular risk factors |
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Sciacqua, Angela @@aut@@ Perticone, Maria @@aut@@ Tripepi, Giovanni @@aut@@ Tassone, Eliezer J. @@aut@@ Cimellaro, Antonio @@aut@@ Mazzaferro, Deborah @@aut@@ Sesti, Giorgio @@aut@@ Perticone, Francesco @@aut@@ |
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2015-05-05T00:00:00Z |
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In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). 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Sciacqua, Angela |
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Sciacqua, Angela ddc 610 bkl 44.80 misc Atrial fibrillation misc CHADS misc score misc CHA misc DS misc -VASc score misc Cardiovascular risk factors $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project |
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610 ASE 44.80 bkl $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project Atrial fibrillation (dpeaa)DE-He213 CHADS (dpeaa)DE-He213 score (dpeaa)DE-He213 CHA (dpeaa)DE-He213 DS (dpeaa)DE-He213 -VASc score (dpeaa)DE-He213 Cardiovascular risk factors (dpeaa)DE-He213 |
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ddc 610 bkl 44.80 misc Atrial fibrillation misc CHADS misc score misc CHA misc DS misc -VASc score misc Cardiovascular risk factors |
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ddc 610 bkl 44.80 misc Atrial fibrillation misc CHADS misc score misc CHA misc DS misc -VASc score misc Cardiovascular risk factors |
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$ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project |
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$ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project |
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Sciacqua, Angela |
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Internal and emergency medicine |
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Internal and emergency medicine |
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Sciacqua, Angela Perticone, Maria Tripepi, Giovanni Tassone, Eliezer J. Cimellaro, Antonio Mazzaferro, Deborah Sesti, Giorgio Perticone, Francesco |
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Elektronische Aufsätze |
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Sciacqua, Angela |
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10.1007/s11739-015-1243-3 |
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610 |
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verfasserin |
| title_sort |
$ chads_{2} $ and $ cha_{2} %$ ds_{2} $-vasc scores are independently associated with incident atrial fibrillation: the catanzaro atrial fibrillation project |
| title_auth |
$ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project |
| abstract |
Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. |
| abstractGer |
Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. |
| abstract_unstemmed |
Abstract No data exist concerning a possible association between $ CHADS_{2} $ or $ CHA_{2} %$ DS_{2} $-VASc scores and atrial fibrillation (AF). In this prospective observational study, we tested the hypothesis whether thromboembolic risk scores predict AF. We investigated 3549 subjects, 1829 men and 1720 women, aged 60.7 ± 10.6 years, without baseline AF. Patients with thyroid disorders were excluded. $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores were evaluated as categorical variables. To test the effect of some clinical confounders on incident AF, we constructed different models including clinical and laboratory parameters. During follow-up (53.3 ± 18.1 months), 546 subjects developed AF (4.5 events/100 patient-years). Progressors to AF are older, have a higher body mass index (BMI), blood pressure, LDL-cholesterol, and glucose. Hypertension, metabolic syndrome, diabetes and carotid wall thickening were more common among AF cases than among control subjects. In the final Cox-regression model, variables that remained significantly associated with incident AF were BMI (HR = 1.022, 95 % CI = 1.008–1.037), LDL-cholesterol (HR = 1.032, 95 % CI = 1.008–1.056), $ CHA_{2} %$ DS_{2} $-VASc score (HR = 1.914, 95 % CI = 1.439–2.546), and $ CHADS_{2} $ score (HR = 2.077, 95 % CI = 1.712–2.521). In conclusion, $ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independent predictors of AF. |
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| title_short |
$ CHADS_{2} $ and $ CHA_{2} %$ DS_{2} $-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project |
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Perticone, Maria Tripepi, Giovanni Tassone, Eliezer J. Cimellaro, Antonio Mazzaferro, Deborah Sesti, Giorgio Perticone, Francesco |
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Perticone, Maria Tripepi, Giovanni Tassone, Eliezer J. Cimellaro, Antonio Mazzaferro, Deborah Sesti, Giorgio Perticone, Francesco |
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| score |
7.4012547 |