Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer
Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effec...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Sclafani, Francesco [verfasserIn] Brown, Gina [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Current colorectal cancer reports - Heidelberg [u.a.] : Springer, 2005, 12(2016), 3 vom: 16. Apr., Seite 130-140 |
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| Übergeordnetes Werk: |
volume:12 ; year:2016 ; number:3 ; day:16 ; month:04 ; pages:130-140 |
| Links: |
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| DOI / URN: |
10.1007/s11888-016-0319-4 |
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| Katalog-ID: |
SPR022890378 |
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| 245 | 1 | 0 | |a Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer |
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| 520 | |a Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. | ||
| 650 | 4 | |a Rectal cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Extramural venous invasion |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a pEMVI |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a mrEMVI |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Tumour regression grading |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a pTRG |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a mrTRG |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Brown, Gina |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Current colorectal cancer reports |d Heidelberg [u.a.] : Springer, 2005 |g 12(2016), 3 vom: 16. Apr., Seite 130-140 |w (DE-627)511638213 |w (DE-600)2233562-6 |x 1556-3804 |7 nnns |
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10.1007/s11888-016-0319-4 doi (DE-627)SPR022890378 (SPR)s11888-016-0319-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Sclafani, Francesco verfasserin aut Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. Rectal cancer (dpeaa)DE-He213 Extramural venous invasion (dpeaa)DE-He213 pEMVI (dpeaa)DE-He213 mrEMVI (dpeaa)DE-He213 Tumour regression grading (dpeaa)DE-He213 pTRG (dpeaa)DE-He213 mrTRG (dpeaa)DE-He213 Brown, Gina verfasserin aut Enthalten in Current colorectal cancer reports Heidelberg [u.a.] : Springer, 2005 12(2016), 3 vom: 16. Apr., Seite 130-140 (DE-627)511638213 (DE-600)2233562-6 1556-3804 nnns volume:12 year:2016 number:3 day:16 month:04 pages:130-140 https://dx.doi.org/10.1007/s11888-016-0319-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 12 2016 3 16 04 130-140 |
| spelling |
10.1007/s11888-016-0319-4 doi (DE-627)SPR022890378 (SPR)s11888-016-0319-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Sclafani, Francesco verfasserin aut Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. Rectal cancer (dpeaa)DE-He213 Extramural venous invasion (dpeaa)DE-He213 pEMVI (dpeaa)DE-He213 mrEMVI (dpeaa)DE-He213 Tumour regression grading (dpeaa)DE-He213 pTRG (dpeaa)DE-He213 mrTRG (dpeaa)DE-He213 Brown, Gina verfasserin aut Enthalten in Current colorectal cancer reports Heidelberg [u.a.] : Springer, 2005 12(2016), 3 vom: 16. Apr., Seite 130-140 (DE-627)511638213 (DE-600)2233562-6 1556-3804 nnns volume:12 year:2016 number:3 day:16 month:04 pages:130-140 https://dx.doi.org/10.1007/s11888-016-0319-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 12 2016 3 16 04 130-140 |
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10.1007/s11888-016-0319-4 doi (DE-627)SPR022890378 (SPR)s11888-016-0319-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Sclafani, Francesco verfasserin aut Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. Rectal cancer (dpeaa)DE-He213 Extramural venous invasion (dpeaa)DE-He213 pEMVI (dpeaa)DE-He213 mrEMVI (dpeaa)DE-He213 Tumour regression grading (dpeaa)DE-He213 pTRG (dpeaa)DE-He213 mrTRG (dpeaa)DE-He213 Brown, Gina verfasserin aut Enthalten in Current colorectal cancer reports Heidelberg [u.a.] : Springer, 2005 12(2016), 3 vom: 16. Apr., Seite 130-140 (DE-627)511638213 (DE-600)2233562-6 1556-3804 nnns volume:12 year:2016 number:3 day:16 month:04 pages:130-140 https://dx.doi.org/10.1007/s11888-016-0319-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 12 2016 3 16 04 130-140 |
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10.1007/s11888-016-0319-4 doi (DE-627)SPR022890378 (SPR)s11888-016-0319-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Sclafani, Francesco verfasserin aut Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. Rectal cancer (dpeaa)DE-He213 Extramural venous invasion (dpeaa)DE-He213 pEMVI (dpeaa)DE-He213 mrEMVI (dpeaa)DE-He213 Tumour regression grading (dpeaa)DE-He213 pTRG (dpeaa)DE-He213 mrTRG (dpeaa)DE-He213 Brown, Gina verfasserin aut Enthalten in Current colorectal cancer reports Heidelberg [u.a.] : Springer, 2005 12(2016), 3 vom: 16. Apr., Seite 130-140 (DE-627)511638213 (DE-600)2233562-6 1556-3804 nnns volume:12 year:2016 number:3 day:16 month:04 pages:130-140 https://dx.doi.org/10.1007/s11888-016-0319-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 12 2016 3 16 04 130-140 |
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10.1007/s11888-016-0319-4 doi (DE-627)SPR022890378 (SPR)s11888-016-0319-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Sclafani, Francesco verfasserin aut Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. Rectal cancer (dpeaa)DE-He213 Extramural venous invasion (dpeaa)DE-He213 pEMVI (dpeaa)DE-He213 mrEMVI (dpeaa)DE-He213 Tumour regression grading (dpeaa)DE-He213 pTRG (dpeaa)DE-He213 mrTRG (dpeaa)DE-He213 Brown, Gina verfasserin aut Enthalten in Current colorectal cancer reports Heidelberg [u.a.] : Springer, 2005 12(2016), 3 vom: 16. Apr., Seite 130-140 (DE-627)511638213 (DE-600)2233562-6 1556-3804 nnns volume:12 year:2016 number:3 day:16 month:04 pages:130-140 https://dx.doi.org/10.1007/s11888-016-0319-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 12 2016 3 16 04 130-140 |
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Enthalten in Current colorectal cancer reports 12(2016), 3 vom: 16. Apr., Seite 130-140 volume:12 year:2016 number:3 day:16 month:04 pages:130-140 |
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Sclafani, Francesco @@aut@@ Brown, Gina @@aut@@ |
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Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. 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|
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Sclafani, Francesco |
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Sclafani, Francesco ddc 610 bkl 44.87 misc Rectal cancer misc Extramural venous invasion misc pEMVI misc mrEMVI misc Tumour regression grading misc pTRG misc mrTRG Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer |
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1556-3804 |
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610 ASE 44.87 bkl Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer Rectal cancer (dpeaa)DE-He213 Extramural venous invasion (dpeaa)DE-He213 pEMVI (dpeaa)DE-He213 mrEMVI (dpeaa)DE-He213 Tumour regression grading (dpeaa)DE-He213 pTRG (dpeaa)DE-He213 mrTRG (dpeaa)DE-He213 |
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ddc 610 bkl 44.87 misc Rectal cancer misc Extramural venous invasion misc pEMVI misc mrEMVI misc Tumour regression grading misc pTRG misc mrTRG |
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ddc 610 bkl 44.87 misc Rectal cancer misc Extramural venous invasion misc pEMVI misc mrEMVI misc Tumour regression grading misc pTRG misc mrTRG |
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ddc 610 bkl 44.87 misc Rectal cancer misc Extramural venous invasion misc pEMVI misc mrEMVI misc Tumour regression grading misc pTRG misc mrTRG |
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Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer |
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Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer |
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Sclafani, Francesco |
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Sclafani, Francesco Brown, Gina |
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extramural venous invasion (emvi) and tumour regression grading (trg) as potential prognostic factors for risk stratification and treatment decision in rectal cancer |
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Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer |
| abstract |
Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. |
| abstractGer |
Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. |
| abstract_unstemmed |
Abstract Routine implementation of risk-adapted therapeutic strategies is one of the highest priorities in the management of locally advanced rectal cancer (LARC). Refinement of risk stratification and better treatment selection have the potential to minimise undesirable treatment-related side effects and improve oncological outcome of patients with this disease. Pathological extramural venous invasion (pEMVI) and tumour regression grade (pTRG) within the resection specimens have been historically regarded as prognostic factors for LARC. More recently, studies have increasingly reported suggesting that these parameters can be detected by high-resolution magnetic resonance imaging (i.e. mrEMVI and mrTRG) significantly widening the opportunities to assess individual patient risk and adapt the treatment plan accordingly. In this article, we review the available evidence on the prognostic role of pEMVI, pTRG, mrEMVI and mrTRG in LARC. Moreover, we discuss how using these prognostic factors in clinical practice may potentially promote the implementation of selected therapeutic strategies in this setting. |
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| container_issue |
3 |
| title_short |
Extramural Venous Invasion (EMVI) and Tumour Regression Grading (TRG) as Potential Prognostic Factors for Risk Stratification and Treatment Decision in Rectal Cancer |
| url |
https://dx.doi.org/10.1007/s11888-016-0319-4 |
| remote_bool |
true |
| author2 |
Brown, Gina |
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Brown, Gina |
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| doi_str |
10.1007/s11888-016-0319-4 |
| up_date |
2024-07-03T15:31:27.372Z |
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|
| score |
7.400546 |