Novel Approaches to Oral Immunization for Hepatitis B

Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediate...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Tiwari, Shailja [verfasserIn] Vyas, Suresh P. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Schlagwörter:	Hepatitis B Hepatitis B surface antigen (HBsAg) Novel drug delivery system Alum Oral immune induction Mucous-associated lymphoid tissue (MALT) Secretory immunoglobulin A (sIgA) M cells Peyer’s patches Adjuvant Liposomes Niosomes Bilisomes Lectin Cholera toxin B Particulate carrier Chitosan Poly(lactic-co-glycolic acids) (PLGA) Humoral immunity Cell-mediated immunity

Übergeordnetes Werk:	Enthalten in: Current infectious disease reports - Heidelberg [u.a.] : Springer, 1999, 13(2010), 1 vom: 07. Dez., Seite 4-12
Übergeordnetes Werk:	volume:13 ; year:2010 ; number:1 ; day:07 ; month:12 ; pages:4-12

Links:	Volltext

DOI / URN:	10.1007/s11908-010-0152-x

Katalog-ID:	SPR022962662

Internformat


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520			\|a Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs.
650		4	\|a Hepatitis B \|7 (dpeaa)DE-He213
650		4	\|a Hepatitis B surface antigen (HBsAg) \|7 (dpeaa)DE-He213
650		4	\|a Novel drug delivery system \|7 (dpeaa)DE-He213
650		4	\|a Alum \|7 (dpeaa)DE-He213
650		4	\|a Oral immune induction \|7 (dpeaa)DE-He213
650		4	\|a Mucous-associated lymphoid tissue (MALT) \|7 (dpeaa)DE-He213
650		4	\|a Secretory immunoglobulin A (sIgA) \|7 (dpeaa)DE-He213
650		4	\|a M cells \|7 (dpeaa)DE-He213
650		4	\|a Peyer’s patches \|7 (dpeaa)DE-He213
650		4	\|a Adjuvant \|7 (dpeaa)DE-He213
650		4	\|a Liposomes \|7 (dpeaa)DE-He213
650		4	\|a Niosomes \|7 (dpeaa)DE-He213
650		4	\|a Bilisomes \|7 (dpeaa)DE-He213
650		4	\|a Lectin \|7 (dpeaa)DE-He213
650		4	\|a Cholera toxin B \|7 (dpeaa)DE-He213
650		4	\|a Particulate carrier \|7 (dpeaa)DE-He213
650		4	\|a Chitosan \|7 (dpeaa)DE-He213
650		4	\|a Poly(lactic-co-glycolic acids) (PLGA) \|7 (dpeaa)DE-He213
650		4	\|a Humoral immunity \|7 (dpeaa)DE-He213
650		4	\|a Cell-mediated immunity \|7 (dpeaa)DE-He213
700	1		\|a Vyas, Suresh P. \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Current infectious disease reports \|d Heidelberg [u.a.] : Springer, 1999 \|g 13(2010), 1 vom: 07. Dez., Seite 4-12 \|w (DE-627)357168305 \|w (DE-600)2094167-5 \|x 1534-3146 \|7 nnns
773	1	8	\|g volume:13 \|g year:2010 \|g number:1 \|g day:07 \|g month:12 \|g pages:4-12
856	4	0	\|u https://dx.doi.org/10.1007/s11908-010-0152-x \|z lizenzpflichtig \|3 Volltext
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912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_120
912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_250
912			\|a GBV_ILN_281
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_636
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2031
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2070
912			\|a GBV_ILN_2086
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2107
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2116
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2119
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2144
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2188
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2446
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2472
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_2548
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4046
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4246
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4336
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
936	b	k	\|a 44.75 \|q ASE
951			\|a AR
952			\|d 13 \|j 2010 \|e 1 \|b 07 \|c 12 \|h 4-12

Indexfelder

author_variant	s t st s p v sp spv
matchkey_str	article:15343146:2010----::oeapocetoaimnzto
hierarchy_sort_str	2010
bklnumber	44.75
publishDate	2010
allfields	10.1007/s11908-010-0152-x doi (DE-627)SPR022962662 (SPR)s11908-010-0152-x-e DE-627 ger DE-627 rakwb eng 610 ASE 44.75 bkl Tiwari, Shailja verfasserin aut Novel Approaches to Oral Immunization for Hepatitis B 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs. Hepatitis B (dpeaa)DE-He213 Hepatitis B surface antigen (HBsAg) (dpeaa)DE-He213 Novel drug delivery system (dpeaa)DE-He213 Alum (dpeaa)DE-He213 Oral immune induction (dpeaa)DE-He213 Mucous-associated lymphoid tissue (MALT) (dpeaa)DE-He213 Secretory immunoglobulin A (sIgA) (dpeaa)DE-He213 M cells (dpeaa)DE-He213 Peyer’s patches (dpeaa)DE-He213 Adjuvant (dpeaa)DE-He213 Liposomes (dpeaa)DE-He213 Niosomes (dpeaa)DE-He213 Bilisomes (dpeaa)DE-He213 Lectin (dpeaa)DE-He213 Cholera toxin B (dpeaa)DE-He213 Particulate carrier (dpeaa)DE-He213 Chitosan (dpeaa)DE-He213 Poly(lactic-co-glycolic acids) (PLGA) (dpeaa)DE-He213 Humoral immunity (dpeaa)DE-He213 Cell-mediated immunity (dpeaa)DE-He213 Vyas, Suresh P. verfasserin aut Enthalten in Current infectious disease reports Heidelberg [u.a.] : Springer, 1999 13(2010), 1 vom: 07. Dez., Seite 4-12 (DE-627)357168305 (DE-600)2094167-5 1534-3146 nnns volume:13 year:2010 number:1 day:07 month:12 pages:4-12 https://dx.doi.org/10.1007/s11908-010-0152-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.75 ASE AR 13 2010 1 07 12 4-12
spelling	10.1007/s11908-010-0152-x doi (DE-627)SPR022962662 (SPR)s11908-010-0152-x-e DE-627 ger DE-627 rakwb eng 610 ASE 44.75 bkl Tiwari, Shailja verfasserin aut Novel Approaches to Oral Immunization for Hepatitis B 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs. Hepatitis B (dpeaa)DE-He213 Hepatitis B surface antigen (HBsAg) (dpeaa)DE-He213 Novel drug delivery system (dpeaa)DE-He213 Alum (dpeaa)DE-He213 Oral immune induction (dpeaa)DE-He213 Mucous-associated lymphoid tissue (MALT) (dpeaa)DE-He213 Secretory immunoglobulin A (sIgA) (dpeaa)DE-He213 M cells (dpeaa)DE-He213 Peyer’s patches (dpeaa)DE-He213 Adjuvant (dpeaa)DE-He213 Liposomes (dpeaa)DE-He213 Niosomes (dpeaa)DE-He213 Bilisomes (dpeaa)DE-He213 Lectin (dpeaa)DE-He213 Cholera toxin B (dpeaa)DE-He213 Particulate carrier (dpeaa)DE-He213 Chitosan (dpeaa)DE-He213 Poly(lactic-co-glycolic acids) (PLGA) (dpeaa)DE-He213 Humoral immunity (dpeaa)DE-He213 Cell-mediated immunity (dpeaa)DE-He213 Vyas, Suresh P. verfasserin aut Enthalten in Current infectious disease reports Heidelberg [u.a.] : Springer, 1999 13(2010), 1 vom: 07. Dez., Seite 4-12 (DE-627)357168305 (DE-600)2094167-5 1534-3146 nnns volume:13 year:2010 number:1 day:07 month:12 pages:4-12 https://dx.doi.org/10.1007/s11908-010-0152-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.75 ASE AR 13 2010 1 07 12 4-12
allfields_unstemmed	10.1007/s11908-010-0152-x doi (DE-627)SPR022962662 (SPR)s11908-010-0152-x-e DE-627 ger DE-627 rakwb eng 610 ASE 44.75 bkl Tiwari, Shailja verfasserin aut Novel Approaches to Oral Immunization for Hepatitis B 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs. Hepatitis B (dpeaa)DE-He213 Hepatitis B surface antigen (HBsAg) (dpeaa)DE-He213 Novel drug delivery system (dpeaa)DE-He213 Alum (dpeaa)DE-He213 Oral immune induction (dpeaa)DE-He213 Mucous-associated lymphoid tissue (MALT) (dpeaa)DE-He213 Secretory immunoglobulin A (sIgA) (dpeaa)DE-He213 M cells (dpeaa)DE-He213 Peyer’s patches (dpeaa)DE-He213 Adjuvant (dpeaa)DE-He213 Liposomes (dpeaa)DE-He213 Niosomes (dpeaa)DE-He213 Bilisomes (dpeaa)DE-He213 Lectin (dpeaa)DE-He213 Cholera toxin B (dpeaa)DE-He213 Particulate carrier (dpeaa)DE-He213 Chitosan (dpeaa)DE-He213 Poly(lactic-co-glycolic acids) (PLGA) (dpeaa)DE-He213 Humoral immunity (dpeaa)DE-He213 Cell-mediated immunity (dpeaa)DE-He213 Vyas, Suresh P. verfasserin aut Enthalten in Current infectious disease reports Heidelberg [u.a.] : Springer, 1999 13(2010), 1 vom: 07. Dez., Seite 4-12 (DE-627)357168305 (DE-600)2094167-5 1534-3146 nnns volume:13 year:2010 number:1 day:07 month:12 pages:4-12 https://dx.doi.org/10.1007/s11908-010-0152-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.75 ASE AR 13 2010 1 07 12 4-12
allfieldsGer	10.1007/s11908-010-0152-x doi (DE-627)SPR022962662 (SPR)s11908-010-0152-x-e DE-627 ger DE-627 rakwb eng 610 ASE 44.75 bkl Tiwari, Shailja verfasserin aut Novel Approaches to Oral Immunization for Hepatitis B 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs. Hepatitis B (dpeaa)DE-He213 Hepatitis B surface antigen (HBsAg) (dpeaa)DE-He213 Novel drug delivery system (dpeaa)DE-He213 Alum (dpeaa)DE-He213 Oral immune induction (dpeaa)DE-He213 Mucous-associated lymphoid tissue (MALT) (dpeaa)DE-He213 Secretory immunoglobulin A (sIgA) (dpeaa)DE-He213 M cells (dpeaa)DE-He213 Peyer’s patches (dpeaa)DE-He213 Adjuvant (dpeaa)DE-He213 Liposomes (dpeaa)DE-He213 Niosomes (dpeaa)DE-He213 Bilisomes (dpeaa)DE-He213 Lectin (dpeaa)DE-He213 Cholera toxin B (dpeaa)DE-He213 Particulate carrier (dpeaa)DE-He213 Chitosan (dpeaa)DE-He213 Poly(lactic-co-glycolic acids) (PLGA) (dpeaa)DE-He213 Humoral immunity (dpeaa)DE-He213 Cell-mediated immunity (dpeaa)DE-He213 Vyas, Suresh P. verfasserin aut Enthalten in Current infectious disease reports Heidelberg [u.a.] : Springer, 1999 13(2010), 1 vom: 07. Dez., Seite 4-12 (DE-627)357168305 (DE-600)2094167-5 1534-3146 nnns volume:13 year:2010 number:1 day:07 month:12 pages:4-12 https://dx.doi.org/10.1007/s11908-010-0152-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.75 ASE AR 13 2010 1 07 12 4-12
allfieldsSound	10.1007/s11908-010-0152-x doi (DE-627)SPR022962662 (SPR)s11908-010-0152-x-e DE-627 ger DE-627 rakwb eng 610 ASE 44.75 bkl Tiwari, Shailja verfasserin aut Novel Approaches to Oral Immunization for Hepatitis B 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs. Hepatitis B (dpeaa)DE-He213 Hepatitis B surface antigen (HBsAg) (dpeaa)DE-He213 Novel drug delivery system (dpeaa)DE-He213 Alum (dpeaa)DE-He213 Oral immune induction (dpeaa)DE-He213 Mucous-associated lymphoid tissue (MALT) (dpeaa)DE-He213 Secretory immunoglobulin A (sIgA) (dpeaa)DE-He213 M cells (dpeaa)DE-He213 Peyer’s patches (dpeaa)DE-He213 Adjuvant (dpeaa)DE-He213 Liposomes (dpeaa)DE-He213 Niosomes (dpeaa)DE-He213 Bilisomes (dpeaa)DE-He213 Lectin (dpeaa)DE-He213 Cholera toxin B (dpeaa)DE-He213 Particulate carrier (dpeaa)DE-He213 Chitosan (dpeaa)DE-He213 Poly(lactic-co-glycolic acids) (PLGA) (dpeaa)DE-He213 Humoral immunity (dpeaa)DE-He213 Cell-mediated immunity (dpeaa)DE-He213 Vyas, Suresh P. verfasserin aut Enthalten in Current infectious disease reports Heidelberg [u.a.] : Springer, 1999 13(2010), 1 vom: 07. Dez., Seite 4-12 (DE-627)357168305 (DE-600)2094167-5 1534-3146 nnns volume:13 year:2010 number:1 day:07 month:12 pages:4-12 https://dx.doi.org/10.1007/s11908-010-0152-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.75 ASE AR 13 2010 1 07 12 4-12
language	English
source	Enthalten in Current infectious disease reports 13(2010), 1 vom: 07. Dez., Seite 4-12 volume:13 year:2010 number:1 day:07 month:12 pages:4-12
sourceStr	Enthalten in Current infectious disease reports 13(2010), 1 vom: 07. Dez., Seite 4-12 volume:13 year:2010 number:1 day:07 month:12 pages:4-12
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Hepatitis B Hepatitis B surface antigen (HBsAg) Novel drug delivery system Alum Oral immune induction Mucous-associated lymphoid tissue (MALT) Secretory immunoglobulin A (sIgA) M cells Peyer’s patches Adjuvant Liposomes Niosomes Bilisomes Lectin Cholera toxin B Particulate carrier Chitosan Poly(lactic-co-glycolic acids) (PLGA) Humoral immunity Cell-mediated immunity
dewey-raw	610
isfreeaccess_bool	false
container_title	Current infectious disease reports
authorswithroles_txt_mv	Tiwari, Shailja @@aut@@ Vyas, Suresh P. @@aut@@
publishDateDaySort_date	2010-12-07T00:00:00Z
hierarchy_top_id	357168305
dewey-sort	3610
id	SPR022962662
language_de	englisch
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author	Tiwari, Shailja
spellingShingle	Tiwari, Shailja ddc 610 bkl 44.75 misc Hepatitis B misc Hepatitis B surface antigen (HBsAg) misc Novel drug delivery system misc Alum misc Oral immune induction misc Mucous-associated lymphoid tissue (MALT) misc Secretory immunoglobulin A (sIgA) misc M cells misc Peyer’s patches misc Adjuvant misc Liposomes misc Niosomes misc Bilisomes misc Lectin misc Cholera toxin B misc Particulate carrier misc Chitosan misc Poly(lactic-co-glycolic acids) (PLGA) misc Humoral immunity misc Cell-mediated immunity Novel Approaches to Oral Immunization for Hepatitis B
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topic_title	610 ASE 44.75 bkl Novel Approaches to Oral Immunization for Hepatitis B Hepatitis B (dpeaa)DE-He213 Hepatitis B surface antigen (HBsAg) (dpeaa)DE-He213 Novel drug delivery system (dpeaa)DE-He213 Alum (dpeaa)DE-He213 Oral immune induction (dpeaa)DE-He213 Mucous-associated lymphoid tissue (MALT) (dpeaa)DE-He213 Secretory immunoglobulin A (sIgA) (dpeaa)DE-He213 M cells (dpeaa)DE-He213 Peyer’s patches (dpeaa)DE-He213 Adjuvant (dpeaa)DE-He213 Liposomes (dpeaa)DE-He213 Niosomes (dpeaa)DE-He213 Bilisomes (dpeaa)DE-He213 Lectin (dpeaa)DE-He213 Cholera toxin B (dpeaa)DE-He213 Particulate carrier (dpeaa)DE-He213 Chitosan (dpeaa)DE-He213 Poly(lactic-co-glycolic acids) (PLGA) (dpeaa)DE-He213 Humoral immunity (dpeaa)DE-He213 Cell-mediated immunity (dpeaa)DE-He213
topic	ddc 610 bkl 44.75 misc Hepatitis B misc Hepatitis B surface antigen (HBsAg) misc Novel drug delivery system misc Alum misc Oral immune induction misc Mucous-associated lymphoid tissue (MALT) misc Secretory immunoglobulin A (sIgA) misc M cells misc Peyer’s patches misc Adjuvant misc Liposomes misc Niosomes misc Bilisomes misc Lectin misc Cholera toxin B misc Particulate carrier misc Chitosan misc Poly(lactic-co-glycolic acids) (PLGA) misc Humoral immunity misc Cell-mediated immunity
topic_unstemmed	ddc 610 bkl 44.75 misc Hepatitis B misc Hepatitis B surface antigen (HBsAg) misc Novel drug delivery system misc Alum misc Oral immune induction misc Mucous-associated lymphoid tissue (MALT) misc Secretory immunoglobulin A (sIgA) misc M cells misc Peyer’s patches misc Adjuvant misc Liposomes misc Niosomes misc Bilisomes misc Lectin misc Cholera toxin B misc Particulate carrier misc Chitosan misc Poly(lactic-co-glycolic acids) (PLGA) misc Humoral immunity misc Cell-mediated immunity
topic_browse	ddc 610 bkl 44.75 misc Hepatitis B misc Hepatitis B surface antigen (HBsAg) misc Novel drug delivery system misc Alum misc Oral immune induction misc Mucous-associated lymphoid tissue (MALT) misc Secretory immunoglobulin A (sIgA) misc M cells misc Peyer’s patches misc Adjuvant misc Liposomes misc Niosomes misc Bilisomes misc Lectin misc Cholera toxin B misc Particulate carrier misc Chitosan misc Poly(lactic-co-glycolic acids) (PLGA) misc Humoral immunity misc Cell-mediated immunity
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title	Novel Approaches to Oral Immunization for Hepatitis B
ctrlnum	(DE-627)SPR022962662 (SPR)s11908-010-0152-x-e
title_full	Novel Approaches to Oral Immunization for Hepatitis B
author_sort	Tiwari, Shailja
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author_browse	Tiwari, Shailja Vyas, Suresh P.
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title_sort	novel approaches to oral immunization for hepatitis b
title_auth	Novel Approaches to Oral Immunization for Hepatitis B
abstract	Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs.
abstractGer	Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs.
abstract_unstemmed	Abstract Hepatitis B is a necroinflammatory liver disease manifested with subacute to acute symptoms, liver cirrhosis, and mortality. Parenteral alum-adsorbed hepatitis B surface antigenic (HBsAg) vaccination, although available, poses serious concerns regarding inability to induce both cell-mediated and mucosal immune response. In this context, oral delivery may be a prospective solution to the issues associated with conventional vaccination. However, the strategy is detrimental to the antigenic substances, suffers various physical/chemical barriers, and impedes poor transcytosis via mucosal route. Therefore, surface-engineered novel carrier-based approaches are reportedly promising for effective HBsAg oral vaccine delivery. This review focuses on the efforts for developing oral mucosal vaccine against hepatitis B, with considerable attention on novel drug delivery systems for spatial distribution of antigenic substance to the immune effector cells and organs.
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container_issue	1
title_short	Novel Approaches to Oral Immunization for Hepatitis B
url	https://dx.doi.org/10.1007/s11908-010-0152-x
remote_bool	true
author2	Vyas, Suresh P.
author2Str	Vyas, Suresh P.
ppnlink	357168305
mediatype_str_mv	c
isOA_txt	false
hochschulschrift_bool	false
doi_str	10.1007/s11908-010-0152-x
up_date	2024-07-03T15:59:43.023Z
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