Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds
Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular in...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Tyno, Ya. Ya. [verfasserIn] Jarigina, E. I. [verfasserIn] Ustinova, V. A. [verfasserIn] Vidrashko, M. T. [verfasserIn] Morosova, G. V. [verfasserIn] Bakaeva, E. V. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Russian agricultural sciences - New York, NY : Allerton Press, 2007, 44(2018), 1 vom: Jan., Seite 97-100 |
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| Übergeordnetes Werk: |
volume:44 ; year:2018 ; number:1 ; month:01 ; pages:97-100 |
| Links: |
|---|
| DOI / URN: |
10.3103/S1068367418010196 |
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| Katalog-ID: |
SPR023370467 |
|---|
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| 245 | 1 | 0 | |a Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds |
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| 520 | |a Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. | ||
| 650 | 4 | |a experimental viral infection |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Marek’s disease |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a herpesvirus of turkey |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Allokin-alpha |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Jarigina, E. I. |e verfasserin |4 aut | |
| 700 | 1 | |a Ustinova, V. A. |e verfasserin |4 aut | |
| 700 | 1 | |a Vidrashko, M. T. |e verfasserin |4 aut | |
| 700 | 1 | |a Morosova, G. V. |e verfasserin |4 aut | |
| 700 | 1 | |a Bakaeva, E. V. |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Russian agricultural sciences |d New York, NY : Allerton Press, 2007 |g 44(2018), 1 vom: Jan., Seite 97-100 |w (DE-627)538633166 |w (DE-600)2379692-3 |x 1934-8037 |7 nnns |
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| 912 | |a GBV_ILN_63 | ||
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| 912 | |a GBV_ILN_70 | ||
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| 912 | |a GBV_ILN_90 | ||
| 912 | |a GBV_ILN_95 | ||
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| 912 | |a GBV_ILN_2038 | ||
| 912 | |a GBV_ILN_2039 | ||
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| 912 | |a GBV_ILN_2065 | ||
| 912 | |a GBV_ILN_2068 | ||
| 912 | |a GBV_ILN_2070 | ||
| 912 | |a GBV_ILN_2086 | ||
| 912 | |a GBV_ILN_2088 | ||
| 912 | |a GBV_ILN_2093 | ||
| 912 | |a GBV_ILN_2106 | ||
| 912 | |a GBV_ILN_2107 | ||
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| 912 | |a GBV_ILN_2110 | ||
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| 912 | |a GBV_ILN_2129 | ||
| 912 | |a GBV_ILN_2143 | ||
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| 912 | |a GBV_ILN_4307 | ||
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| 952 | |d 44 |j 2018 |e 1 |c 01 |h 97-100 | ||
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10.3103/S1068367418010196 doi (DE-627)SPR023370467 (SPR)S1068367418010196-e DE-627 ger DE-627 rakwb eng 630 ASE Tyno, Ya. Ya. verfasserin aut Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. experimental viral infection (dpeaa)DE-He213 Marek’s disease (dpeaa)DE-He213 herpesvirus of turkey (dpeaa)DE-He213 Allokin-alpha (dpeaa)DE-He213 Jarigina, E. I. verfasserin aut Ustinova, V. A. verfasserin aut Vidrashko, M. T. verfasserin aut Morosova, G. V. verfasserin aut Bakaeva, E. V. verfasserin aut Enthalten in Russian agricultural sciences New York, NY : Allerton Press, 2007 44(2018), 1 vom: Jan., Seite 97-100 (DE-627)538633166 (DE-600)2379692-3 1934-8037 nnns volume:44 year:2018 number:1 month:01 pages:97-100 https://dx.doi.org/10.3103/S1068367418010196 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2018 1 01 97-100 |
| spelling |
10.3103/S1068367418010196 doi (DE-627)SPR023370467 (SPR)S1068367418010196-e DE-627 ger DE-627 rakwb eng 630 ASE Tyno, Ya. Ya. verfasserin aut Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. experimental viral infection (dpeaa)DE-He213 Marek’s disease (dpeaa)DE-He213 herpesvirus of turkey (dpeaa)DE-He213 Allokin-alpha (dpeaa)DE-He213 Jarigina, E. I. verfasserin aut Ustinova, V. A. verfasserin aut Vidrashko, M. T. verfasserin aut Morosova, G. V. verfasserin aut Bakaeva, E. V. verfasserin aut Enthalten in Russian agricultural sciences New York, NY : Allerton Press, 2007 44(2018), 1 vom: Jan., Seite 97-100 (DE-627)538633166 (DE-600)2379692-3 1934-8037 nnns volume:44 year:2018 number:1 month:01 pages:97-100 https://dx.doi.org/10.3103/S1068367418010196 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2018 1 01 97-100 |
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10.3103/S1068367418010196 doi (DE-627)SPR023370467 (SPR)S1068367418010196-e DE-627 ger DE-627 rakwb eng 630 ASE Tyno, Ya. Ya. verfasserin aut Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. experimental viral infection (dpeaa)DE-He213 Marek’s disease (dpeaa)DE-He213 herpesvirus of turkey (dpeaa)DE-He213 Allokin-alpha (dpeaa)DE-He213 Jarigina, E. I. verfasserin aut Ustinova, V. A. verfasserin aut Vidrashko, M. T. verfasserin aut Morosova, G. V. verfasserin aut Bakaeva, E. V. verfasserin aut Enthalten in Russian agricultural sciences New York, NY : Allerton Press, 2007 44(2018), 1 vom: Jan., Seite 97-100 (DE-627)538633166 (DE-600)2379692-3 1934-8037 nnns volume:44 year:2018 number:1 month:01 pages:97-100 https://dx.doi.org/10.3103/S1068367418010196 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2018 1 01 97-100 |
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10.3103/S1068367418010196 doi (DE-627)SPR023370467 (SPR)S1068367418010196-e DE-627 ger DE-627 rakwb eng 630 ASE Tyno, Ya. Ya. verfasserin aut Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. experimental viral infection (dpeaa)DE-He213 Marek’s disease (dpeaa)DE-He213 herpesvirus of turkey (dpeaa)DE-He213 Allokin-alpha (dpeaa)DE-He213 Jarigina, E. I. verfasserin aut Ustinova, V. A. verfasserin aut Vidrashko, M. T. verfasserin aut Morosova, G. V. verfasserin aut Bakaeva, E. V. verfasserin aut Enthalten in Russian agricultural sciences New York, NY : Allerton Press, 2007 44(2018), 1 vom: Jan., Seite 97-100 (DE-627)538633166 (DE-600)2379692-3 1934-8037 nnns volume:44 year:2018 number:1 month:01 pages:97-100 https://dx.doi.org/10.3103/S1068367418010196 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2018 1 01 97-100 |
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10.3103/S1068367418010196 doi (DE-627)SPR023370467 (SPR)S1068367418010196-e DE-627 ger DE-627 rakwb eng 630 ASE Tyno, Ya. Ya. verfasserin aut Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. experimental viral infection (dpeaa)DE-He213 Marek’s disease (dpeaa)DE-He213 herpesvirus of turkey (dpeaa)DE-He213 Allokin-alpha (dpeaa)DE-He213 Jarigina, E. I. verfasserin aut Ustinova, V. A. verfasserin aut Vidrashko, M. T. verfasserin aut Morosova, G. V. verfasserin aut Bakaeva, E. V. verfasserin aut Enthalten in Russian agricultural sciences New York, NY : Allerton Press, 2007 44(2018), 1 vom: Jan., Seite 97-100 (DE-627)538633166 (DE-600)2379692-3 1934-8037 nnns volume:44 year:2018 number:1 month:01 pages:97-100 https://dx.doi.org/10.3103/S1068367418010196 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2018 1 01 97-100 |
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Enthalten in Russian agricultural sciences 44(2018), 1 vom: Jan., Seite 97-100 volume:44 year:2018 number:1 month:01 pages:97-100 |
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experimental viral infection Marek’s disease herpesvirus of turkey Allokin-alpha |
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Russian agricultural sciences |
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Tyno, Ya. Ya. @@aut@@ Jarigina, E. I. @@aut@@ Ustinova, V. A. @@aut@@ Vidrashko, M. T. @@aut@@ Morosova, G. V. @@aut@@ Bakaeva, E. V. @@aut@@ |
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Tyno, Ya. Ya. |
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Tyno, Ya. Ya. ddc 630 misc experimental viral infection misc Marek’s disease misc herpesvirus of turkey misc Allokin-alpha Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds |
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630 ASE Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds experimental viral infection (dpeaa)DE-He213 Marek’s disease (dpeaa)DE-He213 herpesvirus of turkey (dpeaa)DE-He213 Allokin-alpha (dpeaa)DE-He213 |
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ddc 630 misc experimental viral infection misc Marek’s disease misc herpesvirus of turkey misc Allokin-alpha |
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Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds |
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Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds |
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Tyno, Ya. Ya. Jarigina, E. I. Ustinova, V. A. Vidrashko, M. T. Morosova, G. V. Bakaeva, E. V. |
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antiviral activity of allokin-alpha against herpesvirus in birds |
| title_auth |
Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds |
| abstract |
Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. |
| abstractGer |
Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. |
| abstract_unstemmed |
Abstract The article reports the efficacy assessment for the Allokin-alpha (Allokin) preparation by modeling the experimental viral infection in vivo in poultry (day-old chickens). The experimental infection included the following steps: vaccination using the vaccine HVT strain, the intramuscular injection of Allokin, and the preparation of feather follicle extracts. The specific antigen was detected in the feather follicle epithelium using the method of gel diffusion precipitation reaction (DPR). A decrease in the number of positive DPR test results for HVT antigen was observed in the case of Allokin-alpha treatment. It has been demonstrated that the optimal time for the Allokin-alpha administration was on the tenth day after the vaccination with HVT as soon as the number of positive DPR results was 33%, while the number of positive results was 50% when the tested preparation was administered 5 and 15 days after the vaccination (samples were collected on day 28 after the vaccination). Since Allokin-alpha has been successfully used to treat human papillomavirus for 15 years, it may also work well as an antiviral agent in the experimental viral infection simulation by the inoculation of vaccine HVT strain; the preparation is not species specific. |
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Antiviral Activity of Allokin-Alpha against Herpesvirus in Birds |
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https://dx.doi.org/10.3103/S1068367418010196 |
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Jarigina, E. I. Ustinova, V. A. Vidrashko, M. T. Morosova, G. V. Bakaeva, E. V. |
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Jarigina, E. I. Ustinova, V. A. Vidrashko, M. T. Morosova, G. V. Bakaeva, E. V. |
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| doi_str |
10.3103/S1068367418010196 |
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2024-07-03T18:31:35.780Z |
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| score |
7.400194 |