Practical NK cell phenotyping and variability in healthy adults
Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety am...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Angelo, Laura S. [verfasserIn] Banerjee, Pinaki P. [verfasserIn] Monaco-Shawver, Linda [verfasserIn] Rosen, Joshua B. [verfasserIn] Makedonas, George [verfasserIn] Forbes, Lisa R. [verfasserIn] Mace, Emily M. [verfasserIn] Orange, Jordan S. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Immunologic research - Totowa, NJ : Humana Press, 1982, 62(2015), 3 vom: 27. Mai, Seite 341-356 |
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| Übergeordnetes Werk: |
volume:62 ; year:2015 ; number:3 ; day:27 ; month:05 ; pages:341-356 |
| Links: |
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| DOI / URN: |
10.1007/s12026-015-8664-y |
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| Katalog-ID: |
SPR023786027 |
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| 100 | 1 | |a Angelo, Laura S. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Practical NK cell phenotyping and variability in healthy adults |
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| 520 | |a Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. | ||
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| 650 | 4 | |a Immunological phenotype |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Primary immune deficiency |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Flow cytometry |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Banerjee, Pinaki P. |e verfasserin |4 aut | |
| 700 | 1 | |a Monaco-Shawver, Linda |e verfasserin |4 aut | |
| 700 | 1 | |a Rosen, Joshua B. |e verfasserin |4 aut | |
| 700 | 1 | |a Makedonas, George |e verfasserin |4 aut | |
| 700 | 1 | |a Forbes, Lisa R. |e verfasserin |4 aut | |
| 700 | 1 | |a Mace, Emily M. |e verfasserin |4 aut | |
| 700 | 1 | |a Orange, Jordan S. |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Immunologic research |d Totowa, NJ : Humana Press, 1982 |g 62(2015), 3 vom: 27. Mai, Seite 341-356 |w (DE-627)348231881 |w (DE-600)2079303-0 |x 1559-0755 |7 nnns |
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| 912 | |a GBV_ILN_2025 | ||
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| 912 | |a GBV_ILN_2027 | ||
| 912 | |a GBV_ILN_2031 | ||
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| 912 | |a GBV_ILN_2037 | ||
| 912 | |a GBV_ILN_2038 | ||
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| 912 | |a GBV_ILN_2044 | ||
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| 912 | |a GBV_ILN_2050 | ||
| 912 | |a GBV_ILN_2055 | ||
| 912 | |a GBV_ILN_2057 | ||
| 912 | |a GBV_ILN_2059 | ||
| 912 | |a GBV_ILN_2061 | ||
| 912 | |a GBV_ILN_2064 | ||
| 912 | |a GBV_ILN_2065 | ||
| 912 | |a GBV_ILN_2068 | ||
| 912 | |a GBV_ILN_2070 | ||
| 912 | |a GBV_ILN_2086 | ||
| 912 | |a GBV_ILN_2088 | ||
| 912 | |a GBV_ILN_2093 | ||
| 912 | |a GBV_ILN_2106 | ||
| 912 | |a GBV_ILN_2107 | ||
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10.1007/s12026-015-8664-y doi (DE-627)SPR023786027 (SPR)s12026-015-8664-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.45 bkl Angelo, Laura S. verfasserin aut Practical NK cell phenotyping and variability in healthy adults 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. NK cells (dpeaa)DE-He213 Immunological phenotype (dpeaa)DE-He213 Primary immune deficiency (dpeaa)DE-He213 Flow cytometry (dpeaa)DE-He213 Banerjee, Pinaki P. verfasserin aut Monaco-Shawver, Linda verfasserin aut Rosen, Joshua B. verfasserin aut Makedonas, George verfasserin aut Forbes, Lisa R. verfasserin aut Mace, Emily M. verfasserin aut Orange, Jordan S. verfasserin aut Enthalten in Immunologic research Totowa, NJ : Humana Press, 1982 62(2015), 3 vom: 27. Mai, Seite 341-356 (DE-627)348231881 (DE-600)2079303-0 1559-0755 nnns volume:62 year:2015 number:3 day:27 month:05 pages:341-356 https://dx.doi.org/10.1007/s12026-015-8664-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.45 ASE AR 62 2015 3 27 05 341-356 |
| spelling |
10.1007/s12026-015-8664-y doi (DE-627)SPR023786027 (SPR)s12026-015-8664-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.45 bkl Angelo, Laura S. verfasserin aut Practical NK cell phenotyping and variability in healthy adults 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. NK cells (dpeaa)DE-He213 Immunological phenotype (dpeaa)DE-He213 Primary immune deficiency (dpeaa)DE-He213 Flow cytometry (dpeaa)DE-He213 Banerjee, Pinaki P. verfasserin aut Monaco-Shawver, Linda verfasserin aut Rosen, Joshua B. verfasserin aut Makedonas, George verfasserin aut Forbes, Lisa R. verfasserin aut Mace, Emily M. verfasserin aut Orange, Jordan S. verfasserin aut Enthalten in Immunologic research Totowa, NJ : Humana Press, 1982 62(2015), 3 vom: 27. Mai, Seite 341-356 (DE-627)348231881 (DE-600)2079303-0 1559-0755 nnns volume:62 year:2015 number:3 day:27 month:05 pages:341-356 https://dx.doi.org/10.1007/s12026-015-8664-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.45 ASE AR 62 2015 3 27 05 341-356 |
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10.1007/s12026-015-8664-y doi (DE-627)SPR023786027 (SPR)s12026-015-8664-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.45 bkl Angelo, Laura S. verfasserin aut Practical NK cell phenotyping and variability in healthy adults 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. NK cells (dpeaa)DE-He213 Immunological phenotype (dpeaa)DE-He213 Primary immune deficiency (dpeaa)DE-He213 Flow cytometry (dpeaa)DE-He213 Banerjee, Pinaki P. verfasserin aut Monaco-Shawver, Linda verfasserin aut Rosen, Joshua B. verfasserin aut Makedonas, George verfasserin aut Forbes, Lisa R. verfasserin aut Mace, Emily M. verfasserin aut Orange, Jordan S. verfasserin aut Enthalten in Immunologic research Totowa, NJ : Humana Press, 1982 62(2015), 3 vom: 27. Mai, Seite 341-356 (DE-627)348231881 (DE-600)2079303-0 1559-0755 nnns volume:62 year:2015 number:3 day:27 month:05 pages:341-356 https://dx.doi.org/10.1007/s12026-015-8664-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.45 ASE AR 62 2015 3 27 05 341-356 |
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10.1007/s12026-015-8664-y doi (DE-627)SPR023786027 (SPR)s12026-015-8664-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.45 bkl Angelo, Laura S. verfasserin aut Practical NK cell phenotyping and variability in healthy adults 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. NK cells (dpeaa)DE-He213 Immunological phenotype (dpeaa)DE-He213 Primary immune deficiency (dpeaa)DE-He213 Flow cytometry (dpeaa)DE-He213 Banerjee, Pinaki P. verfasserin aut Monaco-Shawver, Linda verfasserin aut Rosen, Joshua B. verfasserin aut Makedonas, George verfasserin aut Forbes, Lisa R. verfasserin aut Mace, Emily M. verfasserin aut Orange, Jordan S. verfasserin aut Enthalten in Immunologic research Totowa, NJ : Humana Press, 1982 62(2015), 3 vom: 27. Mai, Seite 341-356 (DE-627)348231881 (DE-600)2079303-0 1559-0755 nnns volume:62 year:2015 number:3 day:27 month:05 pages:341-356 https://dx.doi.org/10.1007/s12026-015-8664-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.45 ASE AR 62 2015 3 27 05 341-356 |
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10.1007/s12026-015-8664-y doi (DE-627)SPR023786027 (SPR)s12026-015-8664-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.45 bkl Angelo, Laura S. verfasserin aut Practical NK cell phenotyping and variability in healthy adults 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. NK cells (dpeaa)DE-He213 Immunological phenotype (dpeaa)DE-He213 Primary immune deficiency (dpeaa)DE-He213 Flow cytometry (dpeaa)DE-He213 Banerjee, Pinaki P. verfasserin aut Monaco-Shawver, Linda verfasserin aut Rosen, Joshua B. verfasserin aut Makedonas, George verfasserin aut Forbes, Lisa R. verfasserin aut Mace, Emily M. verfasserin aut Orange, Jordan S. verfasserin aut Enthalten in Immunologic research Totowa, NJ : Humana Press, 1982 62(2015), 3 vom: 27. Mai, Seite 341-356 (DE-627)348231881 (DE-600)2079303-0 1559-0755 nnns volume:62 year:2015 number:3 day:27 month:05 pages:341-356 https://dx.doi.org/10.1007/s12026-015-8664-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.45 ASE AR 62 2015 3 27 05 341-356 |
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Angelo, Laura S. @@aut@@ Banerjee, Pinaki P. @@aut@@ Monaco-Shawver, Linda @@aut@@ Rosen, Joshua B. @@aut@@ Makedonas, George @@aut@@ Forbes, Lisa R. @@aut@@ Mace, Emily M. @@aut@@ Orange, Jordan S. @@aut@@ |
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Angelo, Laura S. |
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Angelo, Laura S. ddc 610 bkl 44.45 misc NK cells misc Immunological phenotype misc Primary immune deficiency misc Flow cytometry Practical NK cell phenotyping and variability in healthy adults |
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610 ASE 44.45 bkl Practical NK cell phenotyping and variability in healthy adults NK cells (dpeaa)DE-He213 Immunological phenotype (dpeaa)DE-He213 Primary immune deficiency (dpeaa)DE-He213 Flow cytometry (dpeaa)DE-He213 |
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ddc 610 bkl 44.45 misc NK cells misc Immunological phenotype misc Primary immune deficiency misc Flow cytometry |
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Angelo, Laura S. |
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Angelo, Laura S. Banerjee, Pinaki P. Monaco-Shawver, Linda Rosen, Joshua B. Makedonas, George Forbes, Lisa R. Mace, Emily M. Orange, Jordan S. |
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practical nk cell phenotyping and variability in healthy adults |
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Practical NK cell phenotyping and variability in healthy adults |
| abstract |
Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. |
| abstractGer |
Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. |
| abstract_unstemmed |
Abstract Human natural killer (NK) cells display a wide array of surface and intracellular markers that indicate various states of differentiation and/or levels of effector function. These NK cell subsets exist simultaneously in peripheral blood and may vary among individuals. We examined variety among selected NK cell receptors expressed by NK cells from normal donors, as well as the distribution of select NK cell subsets and NK cell receptor expression over time in several individual donors. Peripheral blood mononuclear cells were evaluated using flow cytometry via fluorochrome-conjugated antibodies against a number of NK cell receptors. Results were analyzed for both mean fluorescence intensity (MFI) and the percent positive cells for each receptor. $ CD56^{bright} $ and $ CD56^{dim} $ NK cell subsets were also considered separately, as was variation in receptor expression in NK cell subsets over time in selected individuals. Through this effort, we provide ranges of NK cell surface receptor expression for a local adult population as well as provide insight into intra-individual variation. |
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| container_issue |
3 |
| title_short |
Practical NK cell phenotyping and variability in healthy adults |
| url |
https://dx.doi.org/10.1007/s12026-015-8664-y |
| remote_bool |
true |
| author2 |
Banerjee, Pinaki P. Monaco-Shawver, Linda Rosen, Joshua B. Makedonas, George Forbes, Lisa R. Mace, Emily M. Orange, Jordan S. |
| author2Str |
Banerjee, Pinaki P. Monaco-Shawver, Linda Rosen, Joshua B. Makedonas, George Forbes, Lisa R. Mace, Emily M. Orange, Jordan S. |
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| doi_str |
10.1007/s12026-015-8664-y |
| up_date |
2024-07-03T21:21:59.711Z |
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| score |
7.401025 |