Role of Intrapleural Urokinase in Empyema Thoracis
Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Nandan, Devki [verfasserIn] Agarwal, Sheetal [verfasserIn] Bidhuri, Neha [verfasserIn] Shrivastava, Kavita [verfasserIn] Nanda, Pamali [verfasserIn] Lata, Sandhya [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Indian journal of pediatrics - New Delhi : Dept. of Pediatrics, All India of Medical Sciences, 1933, 86(2019), 12 vom: 18. Okt., Seite 1099-1104 |
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| Übergeordnetes Werk: |
volume:86 ; year:2019 ; number:12 ; day:18 ; month:10 ; pages:1099-1104 |
| Links: |
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| DOI / URN: |
10.1007/s12098-019-03060-w |
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| Katalog-ID: |
SPR024315168 |
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| 520 | |a Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. | ||
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10.1007/s12098-019-03060-w doi (DE-627)SPR024315168 (SPR)s12098-019-03060-w-e DE-627 ger DE-627 rakwb eng 610 ASE 44.67 bkl Nandan, Devki verfasserin aut Role of Intrapleural Urokinase in Empyema Thoracis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. Empyema (dpeaa)DE-He213 Pediatric (dpeaa)DE-He213 Fibrinolytics (dpeaa)DE-He213 Hospital stay (dpeaa)DE-He213 VATS (dpeaa)DE-He213 Agarwal, Sheetal verfasserin aut Bidhuri, Neha verfasserin aut Shrivastava, Kavita verfasserin aut Nanda, Pamali verfasserin aut Lata, Sandhya verfasserin aut Enthalten in Indian journal of pediatrics New Delhi : Dept. of Pediatrics, All India of Medical Sciences, 1933 86(2019), 12 vom: 18. Okt., Seite 1099-1104 (DE-627)340077271 (DE-600)2065273-2 0973-7693 nnns volume:86 year:2019 number:12 day:18 month:10 pages:1099-1104 https://dx.doi.org/10.1007/s12098-019-03060-w lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.67 ASE AR 86 2019 12 18 10 1099-1104 |
| spelling |
10.1007/s12098-019-03060-w doi (DE-627)SPR024315168 (SPR)s12098-019-03060-w-e DE-627 ger DE-627 rakwb eng 610 ASE 44.67 bkl Nandan, Devki verfasserin aut Role of Intrapleural Urokinase in Empyema Thoracis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. Empyema (dpeaa)DE-He213 Pediatric (dpeaa)DE-He213 Fibrinolytics (dpeaa)DE-He213 Hospital stay (dpeaa)DE-He213 VATS (dpeaa)DE-He213 Agarwal, Sheetal verfasserin aut Bidhuri, Neha verfasserin aut Shrivastava, Kavita verfasserin aut Nanda, Pamali verfasserin aut Lata, Sandhya verfasserin aut Enthalten in Indian journal of pediatrics New Delhi : Dept. of Pediatrics, All India of Medical Sciences, 1933 86(2019), 12 vom: 18. Okt., Seite 1099-1104 (DE-627)340077271 (DE-600)2065273-2 0973-7693 nnns volume:86 year:2019 number:12 day:18 month:10 pages:1099-1104 https://dx.doi.org/10.1007/s12098-019-03060-w lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.67 ASE AR 86 2019 12 18 10 1099-1104 |
| allfields_unstemmed |
10.1007/s12098-019-03060-w doi (DE-627)SPR024315168 (SPR)s12098-019-03060-w-e DE-627 ger DE-627 rakwb eng 610 ASE 44.67 bkl Nandan, Devki verfasserin aut Role of Intrapleural Urokinase in Empyema Thoracis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. Empyema (dpeaa)DE-He213 Pediatric (dpeaa)DE-He213 Fibrinolytics (dpeaa)DE-He213 Hospital stay (dpeaa)DE-He213 VATS (dpeaa)DE-He213 Agarwal, Sheetal verfasserin aut Bidhuri, Neha verfasserin aut Shrivastava, Kavita verfasserin aut Nanda, Pamali verfasserin aut Lata, Sandhya verfasserin aut Enthalten in Indian journal of pediatrics New Delhi : Dept. of Pediatrics, All India of Medical Sciences, 1933 86(2019), 12 vom: 18. Okt., Seite 1099-1104 (DE-627)340077271 (DE-600)2065273-2 0973-7693 nnns volume:86 year:2019 number:12 day:18 month:10 pages:1099-1104 https://dx.doi.org/10.1007/s12098-019-03060-w lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.67 ASE AR 86 2019 12 18 10 1099-1104 |
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10.1007/s12098-019-03060-w doi (DE-627)SPR024315168 (SPR)s12098-019-03060-w-e DE-627 ger DE-627 rakwb eng 610 ASE 44.67 bkl Nandan, Devki verfasserin aut Role of Intrapleural Urokinase in Empyema Thoracis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. Empyema (dpeaa)DE-He213 Pediatric (dpeaa)DE-He213 Fibrinolytics (dpeaa)DE-He213 Hospital stay (dpeaa)DE-He213 VATS (dpeaa)DE-He213 Agarwal, Sheetal verfasserin aut Bidhuri, Neha verfasserin aut Shrivastava, Kavita verfasserin aut Nanda, Pamali verfasserin aut Lata, Sandhya verfasserin aut Enthalten in Indian journal of pediatrics New Delhi : Dept. of Pediatrics, All India of Medical Sciences, 1933 86(2019), 12 vom: 18. Okt., Seite 1099-1104 (DE-627)340077271 (DE-600)2065273-2 0973-7693 nnns volume:86 year:2019 number:12 day:18 month:10 pages:1099-1104 https://dx.doi.org/10.1007/s12098-019-03060-w lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.67 ASE AR 86 2019 12 18 10 1099-1104 |
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10.1007/s12098-019-03060-w doi (DE-627)SPR024315168 (SPR)s12098-019-03060-w-e DE-627 ger DE-627 rakwb eng 610 ASE 44.67 bkl Nandan, Devki verfasserin aut Role of Intrapleural Urokinase in Empyema Thoracis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. Empyema (dpeaa)DE-He213 Pediatric (dpeaa)DE-He213 Fibrinolytics (dpeaa)DE-He213 Hospital stay (dpeaa)DE-He213 VATS (dpeaa)DE-He213 Agarwal, Sheetal verfasserin aut Bidhuri, Neha verfasserin aut Shrivastava, Kavita verfasserin aut Nanda, Pamali verfasserin aut Lata, Sandhya verfasserin aut Enthalten in Indian journal of pediatrics New Delhi : Dept. of Pediatrics, All India of Medical Sciences, 1933 86(2019), 12 vom: 18. Okt., Seite 1099-1104 (DE-627)340077271 (DE-600)2065273-2 0973-7693 nnns volume:86 year:2019 number:12 day:18 month:10 pages:1099-1104 https://dx.doi.org/10.1007/s12098-019-03060-w lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.67 ASE AR 86 2019 12 18 10 1099-1104 |
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Enthalten in Indian journal of pediatrics 86(2019), 12 vom: 18. Okt., Seite 1099-1104 volume:86 year:2019 number:12 day:18 month:10 pages:1099-1104 |
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Indian journal of pediatrics |
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Nandan, Devki @@aut@@ Agarwal, Sheetal @@aut@@ Bidhuri, Neha @@aut@@ Shrivastava, Kavita @@aut@@ Nanda, Pamali @@aut@@ Lata, Sandhya @@aut@@ |
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2019-10-18T00:00:00Z |
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Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. 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|
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Nandan, Devki |
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Nandan, Devki ddc 610 bkl 44.67 misc Empyema misc Pediatric misc Fibrinolytics misc Hospital stay misc VATS Role of Intrapleural Urokinase in Empyema Thoracis |
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610 ASE 44.67 bkl Role of Intrapleural Urokinase in Empyema Thoracis Empyema (dpeaa)DE-He213 Pediatric (dpeaa)DE-He213 Fibrinolytics (dpeaa)DE-He213 Hospital stay (dpeaa)DE-He213 VATS (dpeaa)DE-He213 |
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ddc 610 bkl 44.67 misc Empyema misc Pediatric misc Fibrinolytics misc Hospital stay misc VATS |
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Role of Intrapleural Urokinase in Empyema Thoracis |
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Role of Intrapleural Urokinase in Empyema Thoracis |
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Indian journal of pediatrics |
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Nandan, Devki Agarwal, Sheetal Bidhuri, Neha Shrivastava, Kavita Nanda, Pamali Lata, Sandhya |
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role of intrapleural urokinase in empyema thoracis |
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Role of Intrapleural Urokinase in Empyema Thoracis |
| abstract |
Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. |
| abstractGer |
Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. |
| abstract_unstemmed |
Objective To study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge. Methods Retrospective analysis of case records of children <16 y of age admitted in a tertiary care hospital during January 2013 – December 2017 with diagnosis as empyema thoracis was done. Clinico-laboratory characteristics and the primary and secondary outcomes between the group which received intrapleural urokinase (IPU) and the group which did not (non IPU), were compared. Results Of the 84 cases, 40 children received IPU. Mean duration of hospital stay in IPU group (17.51 + 4.57 d) was significantly less than non IPU group (24.32 + 10.18 d, CI –10.19 to −3.64, p < 0.001), so was the duration of intercostal drain (ICD) insertion (9.08 + 3.12 d – IPU group vs. 11.20 + 3.95 d – non IPU group, CI –3.68 to −0.50, p < 0.01). No statistically significant difference was found between the groups with regard to need for surgical intervention [IPU – 4 (10%), non IPU – 9 (20.4%), p = 0.23]. There was no mortality or adverse reaction to urokinase in either group. Conclusions IPU holds promising results in terms of reduction of hospital stay and duration of ICD insertion. It may be the initial choice of treatment in septated empyema where surgical options are not easily available or cost-effective especially in resource limited settings. |
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| container_issue |
12 |
| title_short |
Role of Intrapleural Urokinase in Empyema Thoracis |
| url |
https://dx.doi.org/10.1007/s12098-019-03060-w |
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| author2 |
Agarwal, Sheetal Bidhuri, Neha Shrivastava, Kavita Nanda, Pamali Lata, Sandhya |
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Agarwal, Sheetal Bidhuri, Neha Shrivastava, Kavita Nanda, Pamali Lata, Sandhya |
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10.1007/s12098-019-03060-w |
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2024-07-04T00:26:43.935Z |
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| score |
7.3997498 |