The role of microRNAs (miRNA) in circadian rhythmicity
Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. H...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Pegoraro, Mirko [verfasserIn] Tauber, Eran [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2008 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Journal of Genetics - Springer India, 1955, 87(2008), 5 vom: Dez., Seite 505-511 |
|---|---|
| Übergeordnetes Werk: |
volume:87 ; year:2008 ; number:5 ; month:12 ; pages:505-511 |
| Links: |
|---|
| DOI / URN: |
10.1007/s12041-008-0073-8 |
|---|
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| 520 | |a Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. | ||
| 650 | 4 | |a circadian clock |7 (dpeaa)DE-He213 | |
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10.1007/s12041-008-0073-8 doi (DE-627)SPR02449044X (SPR)s12041-008-0073-8-e DE-627 ger DE-627 rakwb eng Pegoraro, Mirko verfasserin aut The role of microRNAs (miRNA) in circadian rhythmicity 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. circadian clock (dpeaa)DE-He213 chronobiology (dpeaa)DE-He213 microRNA (miRNA) (dpeaa)DE-He213 posttranscriptional regulation (dpeaa)DE-He213 Tauber, Eran verfasserin aut Enthalten in Journal of Genetics Springer India, 1955 87(2008), 5 vom: Dez., Seite 505-511 (DE-627)SPR024069582 nnns volume:87 year:2008 number:5 month:12 pages:505-511 https://dx.doi.org/10.1007/s12041-008-0073-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2002 GBV_ILN_2004 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2012 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2088 GBV_ILN_2190 GBV_ILN_2244 AR 87 2008 5 12 505-511 |
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10.1007/s12041-008-0073-8 doi (DE-627)SPR02449044X (SPR)s12041-008-0073-8-e DE-627 ger DE-627 rakwb eng Pegoraro, Mirko verfasserin aut The role of microRNAs (miRNA) in circadian rhythmicity 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. circadian clock (dpeaa)DE-He213 chronobiology (dpeaa)DE-He213 microRNA (miRNA) (dpeaa)DE-He213 posttranscriptional regulation (dpeaa)DE-He213 Tauber, Eran verfasserin aut Enthalten in Journal of Genetics Springer India, 1955 87(2008), 5 vom: Dez., Seite 505-511 (DE-627)SPR024069582 nnns volume:87 year:2008 number:5 month:12 pages:505-511 https://dx.doi.org/10.1007/s12041-008-0073-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2002 GBV_ILN_2004 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2012 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2088 GBV_ILN_2190 GBV_ILN_2244 AR 87 2008 5 12 505-511 |
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10.1007/s12041-008-0073-8 doi (DE-627)SPR02449044X (SPR)s12041-008-0073-8-e DE-627 ger DE-627 rakwb eng Pegoraro, Mirko verfasserin aut The role of microRNAs (miRNA) in circadian rhythmicity 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. circadian clock (dpeaa)DE-He213 chronobiology (dpeaa)DE-He213 microRNA (miRNA) (dpeaa)DE-He213 posttranscriptional regulation (dpeaa)DE-He213 Tauber, Eran verfasserin aut Enthalten in Journal of Genetics Springer India, 1955 87(2008), 5 vom: Dez., Seite 505-511 (DE-627)SPR024069582 nnns volume:87 year:2008 number:5 month:12 pages:505-511 https://dx.doi.org/10.1007/s12041-008-0073-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2002 GBV_ILN_2004 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2012 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2088 GBV_ILN_2190 GBV_ILN_2244 AR 87 2008 5 12 505-511 |
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10.1007/s12041-008-0073-8 doi (DE-627)SPR02449044X (SPR)s12041-008-0073-8-e DE-627 ger DE-627 rakwb eng Pegoraro, Mirko verfasserin aut The role of microRNAs (miRNA) in circadian rhythmicity 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. circadian clock (dpeaa)DE-He213 chronobiology (dpeaa)DE-He213 microRNA (miRNA) (dpeaa)DE-He213 posttranscriptional regulation (dpeaa)DE-He213 Tauber, Eran verfasserin aut Enthalten in Journal of Genetics Springer India, 1955 87(2008), 5 vom: Dez., Seite 505-511 (DE-627)SPR024069582 nnns volume:87 year:2008 number:5 month:12 pages:505-511 https://dx.doi.org/10.1007/s12041-008-0073-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2002 GBV_ILN_2004 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2012 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2088 GBV_ILN_2190 GBV_ILN_2244 AR 87 2008 5 12 505-511 |
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10.1007/s12041-008-0073-8 doi (DE-627)SPR02449044X (SPR)s12041-008-0073-8-e DE-627 ger DE-627 rakwb eng Pegoraro, Mirko verfasserin aut The role of microRNAs (miRNA) in circadian rhythmicity 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. circadian clock (dpeaa)DE-He213 chronobiology (dpeaa)DE-He213 microRNA (miRNA) (dpeaa)DE-He213 posttranscriptional regulation (dpeaa)DE-He213 Tauber, Eran verfasserin aut Enthalten in Journal of Genetics Springer India, 1955 87(2008), 5 vom: Dez., Seite 505-511 (DE-627)SPR024069582 nnns volume:87 year:2008 number:5 month:12 pages:505-511 https://dx.doi.org/10.1007/s12041-008-0073-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2002 GBV_ILN_2004 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2012 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2088 GBV_ILN_2190 GBV_ILN_2244 AR 87 2008 5 12 505-511 |
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Pegoraro, Mirko Tauber, Eran |
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Elektronische Aufsätze |
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Pegoraro, Mirko |
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10.1007/s12041-008-0073-8 |
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role of micrornas (mirna) in circadian rhythmicity |
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The role of microRNAs (miRNA) in circadian rhythmicity |
| abstract |
Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. |
| abstractGer |
Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. |
| abstract_unstemmed |
Abstract MicroRNA (miRNA) is a recently discovered new class of small RNA molecules that have a significant role in regulating gene and protein expression. These small RNAs (∼22 nt) bind to 3′ untranslated regions (3′ UTRs) and induce degradation or repression of translation of their mRNA targets. Hundreds of miRNAs have been identified in various organisms and have been shown to play a significant role in development and normal cell functioning. Recently, a few studies have suggested that miRNAs may be an important regulators of circadian rhythmicity, providing a new dimension (posttranscriptional) of our understanding of biological clocks. Here, we describe the mechanisms of miRNA regulation, and recent studies attempting to identify clock miRNAs and their function in the circadian system. |
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The role of microRNAs (miRNA) in circadian rhythmicity |
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