Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease

Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multipl...
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Autor*in:	Maeda, Hiromichi [verfasserIn] Nishimori, Isao Okabayashi, Takehiro Kohsaki, Takuhiro Shuin, Taro Kobayashi, Michiya Onishi, Saburo Hanazaki, Kazuhiro

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Schlagwörter:	Von Hippel–Lindau disease (VHLD) gene Mutation Neuroendocrine tumor Total pancreatectomy

Anmerkung:	© Springer 2009

Übergeordnetes Werk:	Enthalten in: Clinical journal of gastroenterology - Tokyo : Springer Japan, 2008, 2(2009), 3 vom: 19. März, Seite 222-225
Übergeordnetes Werk:	volume:2 ; year:2009 ; number:3 ; day:19 ; month:03 ; pages:222-225

Links:	Volltext

DOI / URN:	10.1007/s12328-009-0071-2

Katalog-ID:	SPR024942588

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520			\|a Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment.
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allfields	10.1007/s12328-009-0071-2 doi (DE-627)SPR024942588 (SPR)s12328-009-0071-2-e DE-627 ger DE-627 rakwb eng Maeda, Hiromichi verfasserin aut Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer 2009 Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. Von Hippel–Lindau disease (VHLD) (dpeaa)DE-He213 gene (dpeaa)DE-He213 Mutation (dpeaa)DE-He213 Neuroendocrine tumor (dpeaa)DE-He213 Total pancreatectomy (dpeaa)DE-He213 Nishimori, Isao aut Okabayashi, Takehiro aut Kohsaki, Takuhiro aut Shuin, Taro aut Kobayashi, Michiya aut Onishi, Saburo aut Hanazaki, Kazuhiro aut Enthalten in Clinical journal of gastroenterology Tokyo : Springer Japan, 2008 2(2009), 3 vom: 19. März, Seite 222-225 (DE-627)568491785 (DE-600)2429411-1 1865-7265 nnns volume:2 year:2009 number:3 day:19 month:03 pages:222-225 https://dx.doi.org/10.1007/s12328-009-0071-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2009 3 19 03 222-225
spelling	10.1007/s12328-009-0071-2 doi (DE-627)SPR024942588 (SPR)s12328-009-0071-2-e DE-627 ger DE-627 rakwb eng Maeda, Hiromichi verfasserin aut Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer 2009 Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. Von Hippel–Lindau disease (VHLD) (dpeaa)DE-He213 gene (dpeaa)DE-He213 Mutation (dpeaa)DE-He213 Neuroendocrine tumor (dpeaa)DE-He213 Total pancreatectomy (dpeaa)DE-He213 Nishimori, Isao aut Okabayashi, Takehiro aut Kohsaki, Takuhiro aut Shuin, Taro aut Kobayashi, Michiya aut Onishi, Saburo aut Hanazaki, Kazuhiro aut Enthalten in Clinical journal of gastroenterology Tokyo : Springer Japan, 2008 2(2009), 3 vom: 19. März, Seite 222-225 (DE-627)568491785 (DE-600)2429411-1 1865-7265 nnns volume:2 year:2009 number:3 day:19 month:03 pages:222-225 https://dx.doi.org/10.1007/s12328-009-0071-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2009 3 19 03 222-225
allfields_unstemmed	10.1007/s12328-009-0071-2 doi (DE-627)SPR024942588 (SPR)s12328-009-0071-2-e DE-627 ger DE-627 rakwb eng Maeda, Hiromichi verfasserin aut Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer 2009 Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. Von Hippel–Lindau disease (VHLD) (dpeaa)DE-He213 gene (dpeaa)DE-He213 Mutation (dpeaa)DE-He213 Neuroendocrine tumor (dpeaa)DE-He213 Total pancreatectomy (dpeaa)DE-He213 Nishimori, Isao aut Okabayashi, Takehiro aut Kohsaki, Takuhiro aut Shuin, Taro aut Kobayashi, Michiya aut Onishi, Saburo aut Hanazaki, Kazuhiro aut Enthalten in Clinical journal of gastroenterology Tokyo : Springer Japan, 2008 2(2009), 3 vom: 19. März, Seite 222-225 (DE-627)568491785 (DE-600)2429411-1 1865-7265 nnns volume:2 year:2009 number:3 day:19 month:03 pages:222-225 https://dx.doi.org/10.1007/s12328-009-0071-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2009 3 19 03 222-225
allfieldsGer	10.1007/s12328-009-0071-2 doi (DE-627)SPR024942588 (SPR)s12328-009-0071-2-e DE-627 ger DE-627 rakwb eng Maeda, Hiromichi verfasserin aut Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer 2009 Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. Von Hippel–Lindau disease (VHLD) (dpeaa)DE-He213 gene (dpeaa)DE-He213 Mutation (dpeaa)DE-He213 Neuroendocrine tumor (dpeaa)DE-He213 Total pancreatectomy (dpeaa)DE-He213 Nishimori, Isao aut Okabayashi, Takehiro aut Kohsaki, Takuhiro aut Shuin, Taro aut Kobayashi, Michiya aut Onishi, Saburo aut Hanazaki, Kazuhiro aut Enthalten in Clinical journal of gastroenterology Tokyo : Springer Japan, 2008 2(2009), 3 vom: 19. März, Seite 222-225 (DE-627)568491785 (DE-600)2429411-1 1865-7265 nnns volume:2 year:2009 number:3 day:19 month:03 pages:222-225 https://dx.doi.org/10.1007/s12328-009-0071-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2009 3 19 03 222-225
allfieldsSound	10.1007/s12328-009-0071-2 doi (DE-627)SPR024942588 (SPR)s12328-009-0071-2-e DE-627 ger DE-627 rakwb eng Maeda, Hiromichi verfasserin aut Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer 2009 Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. Von Hippel–Lindau disease (VHLD) (dpeaa)DE-He213 gene (dpeaa)DE-He213 Mutation (dpeaa)DE-He213 Neuroendocrine tumor (dpeaa)DE-He213 Total pancreatectomy (dpeaa)DE-He213 Nishimori, Isao aut Okabayashi, Takehiro aut Kohsaki, Takuhiro aut Shuin, Taro aut Kobayashi, Michiya aut Onishi, Saburo aut Hanazaki, Kazuhiro aut Enthalten in Clinical journal of gastroenterology Tokyo : Springer Japan, 2008 2(2009), 3 vom: 19. März, Seite 222-225 (DE-627)568491785 (DE-600)2429411-1 1865-7265 nnns volume:2 year:2009 number:3 day:19 month:03 pages:222-225 https://dx.doi.org/10.1007/s12328-009-0071-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2009 3 19 03 222-225
language	English
source	Enthalten in Clinical journal of gastroenterology 2(2009), 3 vom: 19. März, Seite 222-225 volume:2 year:2009 number:3 day:19 month:03 pages:222-225
sourceStr	Enthalten in Clinical journal of gastroenterology 2(2009), 3 vom: 19. März, Seite 222-225 volume:2 year:2009 number:3 day:19 month:03 pages:222-225
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institution	findex.gbv.de
topic_facet	Von Hippel–Lindau disease (VHLD) gene Mutation Neuroendocrine tumor Total pancreatectomy
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container_title	Clinical journal of gastroenterology
authorswithroles_txt_mv	Maeda, Hiromichi @@aut@@ Nishimori, Isao @@aut@@ Okabayashi, Takehiro @@aut@@ Kohsaki, Takuhiro @@aut@@ Shuin, Taro @@aut@@ Kobayashi, Michiya @@aut@@ Onishi, Saburo @@aut@@ Hanazaki, Kazuhiro @@aut@@
publishDateDaySort_date	2009-03-19T00:00:00Z
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language_de	englisch
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author	Maeda, Hiromichi
spellingShingle	Maeda, Hiromichi misc Von Hippel–Lindau disease (VHLD) misc gene misc Mutation misc Neuroendocrine tumor misc Total pancreatectomy Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease
authorStr	Maeda, Hiromichi
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topic_title	Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease Von Hippel–Lindau disease (VHLD) (dpeaa)DE-He213 gene (dpeaa)DE-He213 Mutation (dpeaa)DE-He213 Neuroendocrine tumor (dpeaa)DE-He213 Total pancreatectomy (dpeaa)DE-He213
topic	misc Von Hippel–Lindau disease (VHLD) misc gene misc Mutation misc Neuroendocrine tumor misc Total pancreatectomy
topic_unstemmed	misc Von Hippel–Lindau disease (VHLD) misc gene misc Mutation misc Neuroendocrine tumor misc Total pancreatectomy
topic_browse	misc Von Hippel–Lindau disease (VHLD) misc gene misc Mutation misc Neuroendocrine tumor misc Total pancreatectomy
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title	Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease
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title_full	Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease
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author_browse	Maeda, Hiromichi Nishimori, Isao Okabayashi, Takehiro Kohsaki, Takuhiro Shuin, Taro Kobayashi, Michiya Onishi, Saburo Hanazaki, Kazuhiro
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title_sort	total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von hippel–lindau disease
title_auth	Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease
abstract	Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. © Springer 2009
abstractGer	Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. © Springer 2009
abstract_unstemmed	Abstract Von Hippel–Lindau disease (VHLD) is an autosomal dominant familial syndrome associated with multiple neoplasms. Medical management of pancreatic lesions is still controversial, especially for pancreatic neuroendocrine tumors (NET). We report an experience of total pancreatectomy for multiple pancreatic neuroendocrine tumors in a VHLD patient, and discuss the indication of surgical treatment. The patient was a 33-year-old Japanese female with a medical history of VHLD-associated tumors. At 27 years of age, abdominal computed tomography revealed a number of strongly enhanced round tumors throughout the pancreas. She underwent total pancreatectomy with portal vein resection because of back pain and an increase of tumor size. Pathological examination reconfirmed the diagnosis of multiple pancreatic NET invading the portal vein. She has been well with intensive insulin therapy and has shown no recurrence of NET for more than one year. This is a rare case of total pancreatectomy with portal vein resection for treatment of pancreatic NET in a VHLD patient. Total pancreatectomy is a viable option for treatment of multi-centric or extensive pancreatic NET because of a favorable prognosis of NET after radical surgical treatment. © Springer 2009
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title_short	Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease
url	https://dx.doi.org/10.1007/s12328-009-0071-2
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author2	Nishimori, Isao Okabayashi, Takehiro Kohsaki, Takuhiro Shuin, Taro Kobayashi, Michiya Onishi, Saburo Hanazaki, Kazuhiro
author2Str	Nishimori, Isao Okabayashi, Takehiro Kohsaki, Takuhiro Shuin, Taro Kobayashi, Michiya Onishi, Saburo Hanazaki, Kazuhiro
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doi_str	10.1007/s12328-009-0071-2
up_date	2024-07-04T02:55:56.397Z
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Total pancreatectomy for multiple neuroendocrine tumors of the pancreas in a patient with von Hippel–Lindau disease

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