The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients
Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a s...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Mineri, Rossana [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2009 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer-Verlag Italia 2009 |
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| Übergeordnetes Werk: |
Enthalten in: Mediterranean journal of nutrition and metabolism - Birmingham, Ala. : IOS Press, 2008, 1(2009), 3 vom: Jan., Seite 181-185 |
|---|---|
| Übergeordnetes Werk: |
volume:1 ; year:2009 ; number:3 ; month:01 ; pages:181-185 |
| Links: |
|---|
| DOI / URN: |
10.1007/s12349-008-0027-y |
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SPR024961817 |
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| 520 | |a Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. | ||
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10.1007/s12349-008-0027-y doi (DE-627)SPR024961817 (SPR)s12349-008-0027-y-e DE-627 ger DE-627 rakwb eng Mineri, Rossana verfasserin aut The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Italia 2009 Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. Lactose intolerance (dpeaa)DE-He213 Lactase persistence (dpeaa)DE-He213 Diabetes (dpeaa)DE-He213 C/T (13910) (dpeaa)DE-He213 Ghilardi, Giosuè aut Brambilla, Simona aut Sarno, Tiziana aut Bologna, Muriel aut Valaperta, Serenella aut Montanelli, Alessandro aut Enthalten in Mediterranean journal of nutrition and metabolism Birmingham, Ala. : IOS Press, 2008 1(2009), 3 vom: Jan., Seite 181-185 (DE-627)572422792 (DE-600)2438895-6 1973-7998 nnns volume:1 year:2009 number:3 month:01 pages:181-185 https://dx.doi.org/10.1007/s12349-008-0027-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 AR 1 2009 3 01 181-185 |
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10.1007/s12349-008-0027-y doi (DE-627)SPR024961817 (SPR)s12349-008-0027-y-e DE-627 ger DE-627 rakwb eng Mineri, Rossana verfasserin aut The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Italia 2009 Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. Lactose intolerance (dpeaa)DE-He213 Lactase persistence (dpeaa)DE-He213 Diabetes (dpeaa)DE-He213 C/T (13910) (dpeaa)DE-He213 Ghilardi, Giosuè aut Brambilla, Simona aut Sarno, Tiziana aut Bologna, Muriel aut Valaperta, Serenella aut Montanelli, Alessandro aut Enthalten in Mediterranean journal of nutrition and metabolism Birmingham, Ala. : IOS Press, 2008 1(2009), 3 vom: Jan., Seite 181-185 (DE-627)572422792 (DE-600)2438895-6 1973-7998 nnns volume:1 year:2009 number:3 month:01 pages:181-185 https://dx.doi.org/10.1007/s12349-008-0027-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 AR 1 2009 3 01 181-185 |
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10.1007/s12349-008-0027-y doi (DE-627)SPR024961817 (SPR)s12349-008-0027-y-e DE-627 ger DE-627 rakwb eng Mineri, Rossana verfasserin aut The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Italia 2009 Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. Lactose intolerance (dpeaa)DE-He213 Lactase persistence (dpeaa)DE-He213 Diabetes (dpeaa)DE-He213 C/T (13910) (dpeaa)DE-He213 Ghilardi, Giosuè aut Brambilla, Simona aut Sarno, Tiziana aut Bologna, Muriel aut Valaperta, Serenella aut Montanelli, Alessandro aut Enthalten in Mediterranean journal of nutrition and metabolism Birmingham, Ala. : IOS Press, 2008 1(2009), 3 vom: Jan., Seite 181-185 (DE-627)572422792 (DE-600)2438895-6 1973-7998 nnns volume:1 year:2009 number:3 month:01 pages:181-185 https://dx.doi.org/10.1007/s12349-008-0027-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 AR 1 2009 3 01 181-185 |
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10.1007/s12349-008-0027-y doi (DE-627)SPR024961817 (SPR)s12349-008-0027-y-e DE-627 ger DE-627 rakwb eng Mineri, Rossana verfasserin aut The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Italia 2009 Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. Lactose intolerance (dpeaa)DE-He213 Lactase persistence (dpeaa)DE-He213 Diabetes (dpeaa)DE-He213 C/T (13910) (dpeaa)DE-He213 Ghilardi, Giosuè aut Brambilla, Simona aut Sarno, Tiziana aut Bologna, Muriel aut Valaperta, Serenella aut Montanelli, Alessandro aut Enthalten in Mediterranean journal of nutrition and metabolism Birmingham, Ala. : IOS Press, 2008 1(2009), 3 vom: Jan., Seite 181-185 (DE-627)572422792 (DE-600)2438895-6 1973-7998 nnns volume:1 year:2009 number:3 month:01 pages:181-185 https://dx.doi.org/10.1007/s12349-008-0027-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 AR 1 2009 3 01 181-185 |
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10.1007/s12349-008-0027-y doi (DE-627)SPR024961817 (SPR)s12349-008-0027-y-e DE-627 ger DE-627 rakwb eng Mineri, Rossana verfasserin aut The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Italia 2009 Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. Lactose intolerance (dpeaa)DE-He213 Lactase persistence (dpeaa)DE-He213 Diabetes (dpeaa)DE-He213 C/T (13910) (dpeaa)DE-He213 Ghilardi, Giosuè aut Brambilla, Simona aut Sarno, Tiziana aut Bologna, Muriel aut Valaperta, Serenella aut Montanelli, Alessandro aut Enthalten in Mediterranean journal of nutrition and metabolism Birmingham, Ala. : IOS Press, 2008 1(2009), 3 vom: Jan., Seite 181-185 (DE-627)572422792 (DE-600)2438895-6 1973-7998 nnns volume:1 year:2009 number:3 month:01 pages:181-185 https://dx.doi.org/10.1007/s12349-008-0027-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 AR 1 2009 3 01 181-185 |
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The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients Lactose intolerance (dpeaa)DE-He213 Lactase persistence (dpeaa)DE-He213 Diabetes (dpeaa)DE-He213 C/T (13910) (dpeaa)DE-He213 |
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The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients |
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genetic variant of lactase persistence c/t (13910) and blood glucose control in type 1 diabetes mellitus patients |
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The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients |
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Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. © Springer-Verlag Italia 2009 |
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Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. © Springer-Verlag Italia 2009 |
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Abstract Lactose intolerance is found in 70% of the world-wide population. Lactase activity gradually increases till birth and then, after the early months of life, it physiologically begins to lessen. In about 30% of the population it remains active also as an adult due to a mutation: in Europe a substitution of C with T in position 13910 of the lactase gene. Our data show that CC genotype, associated with lactase non-persistence, is found in type 1 diabetes with a high prevalence of 67%. To evaluate the “glycaemic-metabolic control” we investigated the glycosylated haemoglobin (HbA1c) values and we noted that there is no significant difference between CC (non-absorber) and CT/TT (absorber) genotypes of diabetic patients. Glutamic acid decarboxylase antibodies (GADA) are positive in 58% of diabetic patients with CC genotype: this presence could be linked to the intestinal membrane hyperpermeability. © Springer-Verlag Italia 2009 |
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The genetic variant of lactase persistence C/T (13910) and blood glucose control in type 1 diabetes mellitus patients |
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