PS5 - 26. Modulation of GLP-1 secreting L-cells derived from intestinal stem cells
Abstract Glucagon-like peptide 1 (GLP-1) is produced by intestinal L-cells, augments insulin secretion and plays an important role in glucose homeostasis. Enhancing endogenous GLP-1 secretion improves glycemic control in patients with type 2 diabetes. However, it is not clear how a change in L-cell...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Petersen, Natalia [verfasserIn] van Gurp, Léon [verfasserIn] Farin, Henner [verfasserIn] van den Brink, Stieneke [verfasserIn] Clevers, Hans [verfasserIn] de Koning, Eelco [verfasserIn] |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2011 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Nederlands Tijdschrift voor Diabetologie - Houten : Bohn Stafleu Van Loghum, 2014, 9(2011), 3 vom: Nov., Seite 108-108 |
|---|---|
| Übergeordnetes Werk: |
volume:9 ; year:2011 ; number:3 ; month:11 ; pages:108-108 |
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|---|
| DOI / URN: |
10.1007/s12467-011-0051-2 |
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Abstract Glucagon-like peptide 1 (GLP-1) is produced by intestinal L-cells, augments insulin secretion and plays an important role in glucose homeostasis. Enhancing endogenous GLP-1 secretion improves glycemic control in patients with type 2 diabetes. However, it is not clear how a change in L-cell number could contribute to circulating GLP-1 levels in physiological conditions and in type 2 diabetes. |
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Abstract Glucagon-like peptide 1 (GLP-1) is produced by intestinal L-cells, augments insulin secretion and plays an important role in glucose homeostasis. Enhancing endogenous GLP-1 secretion improves glycemic control in patients with type 2 diabetes. However, it is not clear how a change in L-cell number could contribute to circulating GLP-1 levels in physiological conditions and in type 2 diabetes. |
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