Influence of age and hematocrit on the coagulation of blood
Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalci...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ujiie, Hiroshi [verfasserIn] |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2009 |
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| Schlagwörter: |
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| Anmerkung: |
© Japanese Society of Biorheology 2010 |
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| Übergeordnetes Werk: |
Enthalten in: Journal of biorheology - Tokyo : Springer Japan, 2009, 23(2009), 2 vom: Dez., Seite 111-114 |
|---|---|
| Übergeordnetes Werk: |
volume:23 ; year:2009 ; number:2 ; month:12 ; pages:111-114 |
| Links: |
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| DOI / URN: |
10.1007/s12573-010-0015-y |
|---|
| Katalog-ID: |
SPR026157284 |
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| 520 | |a Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. | ||
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10.1007/s12573-010-0015-y doi (DE-627)SPR026157284 (SPR)s12573-010-0015-y-e DE-627 ger DE-627 rakwb eng Ujiie, Hiroshi verfasserin aut Influence of age and hematocrit on the coagulation of blood 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Japanese Society of Biorheology 2010 Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. Blood coagulation (dpeaa)DE-He213 Hematocrit (dpeaa)DE-He213 Age (dpeaa)DE-He213 Blood viscosity (dpeaa)DE-He213 Shear rate (dpeaa)DE-He213 Kawasaki, Mineo aut Suzuki, Yoshiaki aut Kaibara, Makoto aut Enthalten in Journal of biorheology Tokyo : Springer Japan, 2009 23(2009), 2 vom: Dez., Seite 111-114 (DE-627)599678593 (DE-600)2494380-0 1867-0474 nnns volume:23 year:2009 number:2 month:12 pages:111-114 https://dx.doi.org/10.1007/s12573-010-0015-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_70 GBV_ILN_702 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4307 GBV_ILN_4323 GBV_ILN_4338 AR 23 2009 2 12 111-114 |
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10.1007/s12573-010-0015-y doi (DE-627)SPR026157284 (SPR)s12573-010-0015-y-e DE-627 ger DE-627 rakwb eng Ujiie, Hiroshi verfasserin aut Influence of age and hematocrit on the coagulation of blood 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Japanese Society of Biorheology 2010 Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. Blood coagulation (dpeaa)DE-He213 Hematocrit (dpeaa)DE-He213 Age (dpeaa)DE-He213 Blood viscosity (dpeaa)DE-He213 Shear rate (dpeaa)DE-He213 Kawasaki, Mineo aut Suzuki, Yoshiaki aut Kaibara, Makoto aut Enthalten in Journal of biorheology Tokyo : Springer Japan, 2009 23(2009), 2 vom: Dez., Seite 111-114 (DE-627)599678593 (DE-600)2494380-0 1867-0474 nnns volume:23 year:2009 number:2 month:12 pages:111-114 https://dx.doi.org/10.1007/s12573-010-0015-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_70 GBV_ILN_702 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4307 GBV_ILN_4323 GBV_ILN_4338 AR 23 2009 2 12 111-114 |
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10.1007/s12573-010-0015-y doi (DE-627)SPR026157284 (SPR)s12573-010-0015-y-e DE-627 ger DE-627 rakwb eng Ujiie, Hiroshi verfasserin aut Influence of age and hematocrit on the coagulation of blood 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Japanese Society of Biorheology 2010 Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. Blood coagulation (dpeaa)DE-He213 Hematocrit (dpeaa)DE-He213 Age (dpeaa)DE-He213 Blood viscosity (dpeaa)DE-He213 Shear rate (dpeaa)DE-He213 Kawasaki, Mineo aut Suzuki, Yoshiaki aut Kaibara, Makoto aut Enthalten in Journal of biorheology Tokyo : Springer Japan, 2009 23(2009), 2 vom: Dez., Seite 111-114 (DE-627)599678593 (DE-600)2494380-0 1867-0474 nnns volume:23 year:2009 number:2 month:12 pages:111-114 https://dx.doi.org/10.1007/s12573-010-0015-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_70 GBV_ILN_702 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4307 GBV_ILN_4323 GBV_ILN_4338 AR 23 2009 2 12 111-114 |
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10.1007/s12573-010-0015-y doi (DE-627)SPR026157284 (SPR)s12573-010-0015-y-e DE-627 ger DE-627 rakwb eng Ujiie, Hiroshi verfasserin aut Influence of age and hematocrit on the coagulation of blood 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Japanese Society of Biorheology 2010 Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. Blood coagulation (dpeaa)DE-He213 Hematocrit (dpeaa)DE-He213 Age (dpeaa)DE-He213 Blood viscosity (dpeaa)DE-He213 Shear rate (dpeaa)DE-He213 Kawasaki, Mineo aut Suzuki, Yoshiaki aut Kaibara, Makoto aut Enthalten in Journal of biorheology Tokyo : Springer Japan, 2009 23(2009), 2 vom: Dez., Seite 111-114 (DE-627)599678593 (DE-600)2494380-0 1867-0474 nnns volume:23 year:2009 number:2 month:12 pages:111-114 https://dx.doi.org/10.1007/s12573-010-0015-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_70 GBV_ILN_702 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4307 GBV_ILN_4323 GBV_ILN_4338 AR 23 2009 2 12 111-114 |
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10.1007/s12573-010-0015-y doi (DE-627)SPR026157284 (SPR)s12573-010-0015-y-e DE-627 ger DE-627 rakwb eng Ujiie, Hiroshi verfasserin aut Influence of age and hematocrit on the coagulation of blood 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Japanese Society of Biorheology 2010 Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. Blood coagulation (dpeaa)DE-He213 Hematocrit (dpeaa)DE-He213 Age (dpeaa)DE-He213 Blood viscosity (dpeaa)DE-He213 Shear rate (dpeaa)DE-He213 Kawasaki, Mineo aut Suzuki, Yoshiaki aut Kaibara, Makoto aut Enthalten in Journal of biorheology Tokyo : Springer Japan, 2009 23(2009), 2 vom: Dez., Seite 111-114 (DE-627)599678593 (DE-600)2494380-0 1867-0474 nnns volume:23 year:2009 number:2 month:12 pages:111-114 https://dx.doi.org/10.1007/s12573-010-0015-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_70 GBV_ILN_702 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4307 GBV_ILN_4323 GBV_ILN_4338 AR 23 2009 2 12 111-114 |
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Influence of age and hematocrit on the coagulation of blood Blood coagulation (dpeaa)DE-He213 Hematocrit (dpeaa)DE-He213 Age (dpeaa)DE-He213 Blood viscosity (dpeaa)DE-He213 Shear rate (dpeaa)DE-He213 |
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Influence of age and hematocrit on the coagulation of blood |
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Ujiie, Hiroshi |
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Ujiie, Hiroshi Kawasaki, Mineo Suzuki, Yoshiaki Kaibara, Makoto |
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Ujiie, Hiroshi |
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influence of age and hematocrit on the coagulation of blood |
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Influence of age and hematocrit on the coagulation of blood |
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Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. © Japanese Society of Biorheology 2010 |
| abstractGer |
Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. © Japanese Society of Biorheology 2010 |
| abstract_unstemmed |
Abstract To examine the effects of age, hematocrit and the daily variation in hematocrit on coagulation of blood, the time of onset of coagulation (Ti) of whole blood obtained from donors including normal subjects and patients was measured by means of a rheological technique. The Ti value of recalcified blood decreased with an increase in age, but in donors aged 65 years or more (the elderly), the Ti value was almost independent of age. The Ti value for blood obtained from the elderly was significantly lower at lower hematocrit levels, but that for blood obtained from young donors was almost independent of hematocrit. The daily variation in hematocrit in individuals was small (maximum variation: about 4%), and the variation had little effect on the Ti value. However, a slight increase in hematocrit was considered to bring about a significant increase in viscosity at lower shear rates. Therefore, it is suggested that a slight increase in hematocrit under stagnant flow conditions is one of major risk factors for venous thrombogenesis, especially in the elderly. © Japanese Society of Biorheology 2010 |
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Influence of age and hematocrit on the coagulation of blood |
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