Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?

Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognosti...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Jeruss, Jacqueline S. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Schlagwörter:	Radiat Oncol Biol Phys Local Recurrence Rate Operable Breast Cancer Completion Axillary Lymph Node Dissection Completion Axillary Dissection

Anmerkung:	© Current Medicine Group, LLC 2009

Übergeordnetes Werk:	Enthalten in: Current breast cancer reports - Philadelphia, Pa. : Current Medicine Group LLC, 2009, 1(2009), 2 vom: 22. Mai, Seite 90-97
Übergeordnetes Werk:	volume:1 ; year:2009 ; number:2 ; day:22 ; month:05 ; pages:90-97

Links:	Volltext

DOI / URN:	10.1007/s12609-009-0013-5

Katalog-ID:	SPR026338297

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520			\|a Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed.
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allfields	10.1007/s12609-009-0013-5 doi (DE-627)SPR026338297 (SPR)s12609-009-0013-5-e DE-627 ger DE-627 rakwb eng Jeruss, Jacqueline S. verfasserin aut Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging? 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Current Medicine Group, LLC 2009 Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. Radiat Oncol Biol Phys (dpeaa)DE-He213 Local Recurrence Rate (dpeaa)DE-He213 Operable Breast Cancer (dpeaa)DE-He213 Completion Axillary Lymph Node Dissection (dpeaa)DE-He213 Completion Axillary Dissection (dpeaa)DE-He213 Enthalten in Current breast cancer reports Philadelphia, Pa. : Current Medicine Group LLC, 2009 1(2009), 2 vom: 22. Mai, Seite 90-97 (DE-627)59967461X (DE-600)2493862-2 1943-4596 nnns volume:1 year:2009 number:2 day:22 month:05 pages:90-97 https://dx.doi.org/10.1007/s12609-009-0013-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 1 2009 2 22 05 90-97
spelling	10.1007/s12609-009-0013-5 doi (DE-627)SPR026338297 (SPR)s12609-009-0013-5-e DE-627 ger DE-627 rakwb eng Jeruss, Jacqueline S. verfasserin aut Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging? 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Current Medicine Group, LLC 2009 Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. Radiat Oncol Biol Phys (dpeaa)DE-He213 Local Recurrence Rate (dpeaa)DE-He213 Operable Breast Cancer (dpeaa)DE-He213 Completion Axillary Lymph Node Dissection (dpeaa)DE-He213 Completion Axillary Dissection (dpeaa)DE-He213 Enthalten in Current breast cancer reports Philadelphia, Pa. : Current Medicine Group LLC, 2009 1(2009), 2 vom: 22. Mai, Seite 90-97 (DE-627)59967461X (DE-600)2493862-2 1943-4596 nnns volume:1 year:2009 number:2 day:22 month:05 pages:90-97 https://dx.doi.org/10.1007/s12609-009-0013-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 1 2009 2 22 05 90-97
allfields_unstemmed	10.1007/s12609-009-0013-5 doi (DE-627)SPR026338297 (SPR)s12609-009-0013-5-e DE-627 ger DE-627 rakwb eng Jeruss, Jacqueline S. verfasserin aut Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging? 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Current Medicine Group, LLC 2009 Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. Radiat Oncol Biol Phys (dpeaa)DE-He213 Local Recurrence Rate (dpeaa)DE-He213 Operable Breast Cancer (dpeaa)DE-He213 Completion Axillary Lymph Node Dissection (dpeaa)DE-He213 Completion Axillary Dissection (dpeaa)DE-He213 Enthalten in Current breast cancer reports Philadelphia, Pa. : Current Medicine Group LLC, 2009 1(2009), 2 vom: 22. Mai, Seite 90-97 (DE-627)59967461X (DE-600)2493862-2 1943-4596 nnns volume:1 year:2009 number:2 day:22 month:05 pages:90-97 https://dx.doi.org/10.1007/s12609-009-0013-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 1 2009 2 22 05 90-97
allfieldsGer	10.1007/s12609-009-0013-5 doi (DE-627)SPR026338297 (SPR)s12609-009-0013-5-e DE-627 ger DE-627 rakwb eng Jeruss, Jacqueline S. verfasserin aut Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging? 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Current Medicine Group, LLC 2009 Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. Radiat Oncol Biol Phys (dpeaa)DE-He213 Local Recurrence Rate (dpeaa)DE-He213 Operable Breast Cancer (dpeaa)DE-He213 Completion Axillary Lymph Node Dissection (dpeaa)DE-He213 Completion Axillary Dissection (dpeaa)DE-He213 Enthalten in Current breast cancer reports Philadelphia, Pa. : Current Medicine Group LLC, 2009 1(2009), 2 vom: 22. Mai, Seite 90-97 (DE-627)59967461X (DE-600)2493862-2 1943-4596 nnns volume:1 year:2009 number:2 day:22 month:05 pages:90-97 https://dx.doi.org/10.1007/s12609-009-0013-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 1 2009 2 22 05 90-97
allfieldsSound	10.1007/s12609-009-0013-5 doi (DE-627)SPR026338297 (SPR)s12609-009-0013-5-e DE-627 ger DE-627 rakwb eng Jeruss, Jacqueline S. verfasserin aut Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging? 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Current Medicine Group, LLC 2009 Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. Radiat Oncol Biol Phys (dpeaa)DE-He213 Local Recurrence Rate (dpeaa)DE-He213 Operable Breast Cancer (dpeaa)DE-He213 Completion Axillary Lymph Node Dissection (dpeaa)DE-He213 Completion Axillary Dissection (dpeaa)DE-He213 Enthalten in Current breast cancer reports Philadelphia, Pa. : Current Medicine Group LLC, 2009 1(2009), 2 vom: 22. Mai, Seite 90-97 (DE-627)59967461X (DE-600)2493862-2 1943-4596 nnns volume:1 year:2009 number:2 day:22 month:05 pages:90-97 https://dx.doi.org/10.1007/s12609-009-0013-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 1 2009 2 22 05 90-97
language	English
source	Enthalten in Current breast cancer reports 1(2009), 2 vom: 22. Mai, Seite 90-97 volume:1 year:2009 number:2 day:22 month:05 pages:90-97
sourceStr	Enthalten in Current breast cancer reports 1(2009), 2 vom: 22. Mai, Seite 90-97 volume:1 year:2009 number:2 day:22 month:05 pages:90-97
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Radiat Oncol Biol Phys Local Recurrence Rate Operable Breast Cancer Completion Axillary Lymph Node Dissection Completion Axillary Dissection
isfreeaccess_bool	false
container_title	Current breast cancer reports
authorswithroles_txt_mv	Jeruss, Jacqueline S. @@aut@@
publishDateDaySort_date	2009-05-22T00:00:00Z
hierarchy_top_id	59967461X
id	SPR026338297
language_de	englisch
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author	Jeruss, Jacqueline S.
spellingShingle	Jeruss, Jacqueline S. misc Radiat Oncol Biol Phys misc Local Recurrence Rate misc Operable Breast Cancer misc Completion Axillary Lymph Node Dissection misc Completion Axillary Dissection Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?
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topic_title	Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging? Radiat Oncol Biol Phys (dpeaa)DE-He213 Local Recurrence Rate (dpeaa)DE-He213 Operable Breast Cancer (dpeaa)DE-He213 Completion Axillary Lymph Node Dissection (dpeaa)DE-He213 Completion Axillary Dissection (dpeaa)DE-He213
topic	misc Radiat Oncol Biol Phys misc Local Recurrence Rate misc Operable Breast Cancer misc Completion Axillary Lymph Node Dissection misc Completion Axillary Dissection
topic_unstemmed	misc Radiat Oncol Biol Phys misc Local Recurrence Rate misc Operable Breast Cancer misc Completion Axillary Lymph Node Dissection misc Completion Axillary Dissection
topic_browse	misc Radiat Oncol Biol Phys misc Local Recurrence Rate misc Operable Breast Cancer misc Completion Axillary Lymph Node Dissection misc Completion Axillary Dissection
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title	Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?
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title_full	Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?
author_sort	Jeruss, Jacqueline S.
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title_sort	prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: pretreatment clinical staging or posttreatment pathologic staging?
title_auth	Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?
abstract	Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. © Current Medicine Group, LLC 2009
abstractGer	Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. © Current Medicine Group, LLC 2009
abstract_unstemmed	Abstract Presurgical chemotherapy is increasingly implemented as it improves breast conservation rates and may reveal novel information about therapeutic response. However, neoadjuvant therapy raises questions about prognosis and decision making for adjuvant local-regional therapy. Current prognostic information and therapeutic treatment planning is typically based on American Joint Committee on Cancer staging information for patients treated with adjuvant therapy. This information is not readily applicable to patients treated with neoadjuvant chemotherapy, however, as neither pretreatment clinical staging data nor post-treatment pathologic data alone accurately reflect disease status. This review summarizes the implementation of a new staging system for patients receiving neoadjuvant therapy. This system combines clinical and pathologic staging factors with biologic markers to refine the prognostic assessment of patients treated with neoadjuvant therapy. Controversies related to neoadjuvant therapy and sentinel lymph node biopsy, postmastectomy radiation therapy, and breast conservation are also discussed. © Current Medicine Group, LLC 2009
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title_short	Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?
url	https://dx.doi.org/10.1007/s12609-009-0013-5
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doi_str	10.1007/s12609-009-0013-5
up_date	2024-07-03T20:20:15.102Z
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Prognostic outcomes and decision-making for local-regional therapy after neoadjuvant chemotherapy: Pretreatment clinical staging or posttreatment pathologic staging?

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