Testicular microlithiasis and testicular tumor: a review of the literature
Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and t...
Ausführliche Beschreibung
Autor*in: |
Leblanc, Louis [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2018 |
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Anmerkung: |
© The Author(s). 2018 |
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Übergeordnetes Werk: |
Enthalten in: Andrologie - Paris [u.a.] : Springer, 1991, 28(2018), 1 vom: 09. Juli |
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Übergeordnetes Werk: |
volume:28 ; year:2018 ; number:1 ; day:09 ; month:07 |
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DOI / URN: |
10.1186/s12610-018-0073-3 |
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Katalog-ID: |
SPR026347199 |
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520 | |a Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. | ||
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10.1186/s12610-018-0073-3 doi (DE-627)SPR026347199 (SPR)s12610-018-0073-3-e DE-627 ger DE-627 rakwb eng Leblanc, Louis verfasserin aut Testicular microlithiasis and testicular tumor: a review of the literature 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. Testicular microlithiasis (dpeaa)DE-He213 Testicular tumor (dpeaa)DE-He213 Testicular cancer (dpeaa)DE-He213 Germ cell tumor (dpeaa)DE-He213 Infertility (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Lagrange, François aut Lecoanet, Pierre aut Marçon, Baptiste aut Eschwege, Pascal aut Hubert, Jacques aut Enthalten in Andrologie Paris [u.a.] : Springer, 1991 28(2018), 1 vom: 09. Juli (DE-627)595710743 (DE-600)2486872-3 1760-5377 nnns volume:28 year:2018 number:1 day:09 month:07 https://dx.doi.org/10.1186/s12610-018-0073-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_266 GBV_ILN_281 AR 28 2018 1 09 07 |
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10.1186/s12610-018-0073-3 doi (DE-627)SPR026347199 (SPR)s12610-018-0073-3-e DE-627 ger DE-627 rakwb eng Leblanc, Louis verfasserin aut Testicular microlithiasis and testicular tumor: a review of the literature 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. Testicular microlithiasis (dpeaa)DE-He213 Testicular tumor (dpeaa)DE-He213 Testicular cancer (dpeaa)DE-He213 Germ cell tumor (dpeaa)DE-He213 Infertility (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Lagrange, François aut Lecoanet, Pierre aut Marçon, Baptiste aut Eschwege, Pascal aut Hubert, Jacques aut Enthalten in Andrologie Paris [u.a.] : Springer, 1991 28(2018), 1 vom: 09. Juli (DE-627)595710743 (DE-600)2486872-3 1760-5377 nnns volume:28 year:2018 number:1 day:09 month:07 https://dx.doi.org/10.1186/s12610-018-0073-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_266 GBV_ILN_281 AR 28 2018 1 09 07 |
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10.1186/s12610-018-0073-3 doi (DE-627)SPR026347199 (SPR)s12610-018-0073-3-e DE-627 ger DE-627 rakwb eng Leblanc, Louis verfasserin aut Testicular microlithiasis and testicular tumor: a review of the literature 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. Testicular microlithiasis (dpeaa)DE-He213 Testicular tumor (dpeaa)DE-He213 Testicular cancer (dpeaa)DE-He213 Germ cell tumor (dpeaa)DE-He213 Infertility (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Lagrange, François aut Lecoanet, Pierre aut Marçon, Baptiste aut Eschwege, Pascal aut Hubert, Jacques aut Enthalten in Andrologie Paris [u.a.] : Springer, 1991 28(2018), 1 vom: 09. Juli (DE-627)595710743 (DE-600)2486872-3 1760-5377 nnns volume:28 year:2018 number:1 day:09 month:07 https://dx.doi.org/10.1186/s12610-018-0073-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_266 GBV_ILN_281 AR 28 2018 1 09 07 |
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10.1186/s12610-018-0073-3 doi (DE-627)SPR026347199 (SPR)s12610-018-0073-3-e DE-627 ger DE-627 rakwb eng Leblanc, Louis verfasserin aut Testicular microlithiasis and testicular tumor: a review of the literature 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. Testicular microlithiasis (dpeaa)DE-He213 Testicular tumor (dpeaa)DE-He213 Testicular cancer (dpeaa)DE-He213 Germ cell tumor (dpeaa)DE-He213 Infertility (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Lagrange, François aut Lecoanet, Pierre aut Marçon, Baptiste aut Eschwege, Pascal aut Hubert, Jacques aut Enthalten in Andrologie Paris [u.a.] : Springer, 1991 28(2018), 1 vom: 09. Juli (DE-627)595710743 (DE-600)2486872-3 1760-5377 nnns volume:28 year:2018 number:1 day:09 month:07 https://dx.doi.org/10.1186/s12610-018-0073-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_266 GBV_ILN_281 AR 28 2018 1 09 07 |
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10.1186/s12610-018-0073-3 doi (DE-627)SPR026347199 (SPR)s12610-018-0073-3-e DE-627 ger DE-627 rakwb eng Leblanc, Louis verfasserin aut Testicular microlithiasis and testicular tumor: a review of the literature 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. Testicular microlithiasis (dpeaa)DE-He213 Testicular tumor (dpeaa)DE-He213 Testicular cancer (dpeaa)DE-He213 Germ cell tumor (dpeaa)DE-He213 Infertility (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Lagrange, François aut Lecoanet, Pierre aut Marçon, Baptiste aut Eschwege, Pascal aut Hubert, Jacques aut Enthalten in Andrologie Paris [u.a.] : Springer, 1991 28(2018), 1 vom: 09. Juli (DE-627)595710743 (DE-600)2486872-3 1760-5377 nnns volume:28 year:2018 number:1 day:09 month:07 https://dx.doi.org/10.1186/s12610-018-0073-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_266 GBV_ILN_281 AR 28 2018 1 09 07 |
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Testicular microlithiasis and testicular tumor: a review of the literature Testicular microlithiasis (dpeaa)DE-He213 Testicular tumor (dpeaa)DE-He213 Testicular cancer (dpeaa)DE-He213 Germ cell tumor (dpeaa)DE-He213 Infertility (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 |
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Testicular microlithiasis and testicular tumor: a review of the literature |
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Testicular microlithiasis and testicular tumor: a review of the literature |
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Leblanc, Louis |
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Leblanc, Louis Lagrange, François Lecoanet, Pierre Marçon, Baptiste Eschwege, Pascal Hubert, Jacques |
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testicular microlithiasis and testicular tumor: a review of the literature |
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Testicular microlithiasis and testicular tumor: a review of the literature |
abstract |
Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. © The Author(s). 2018 |
abstractGer |
Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. © The Author(s). 2018 |
abstract_unstemmed |
Introduction There are numerous scientific publications on testicular microlithiasis (TML) detected during ultrasound (US) examination. We wished to update the data. Methods PubMed was used to identify original articles published between 1998 and May 2017 describing the association between TML and testicular tumor. Studies were only included if TML was diagnosed by US. Studies were then classified into subgroups according to the following criteria: asymptomatic, symptomatic, infertility, cryptorchidism, family or personal history of testicular cancer, and “no given reason for US”. A Z-Test was used to identify differences within these subgroups. In addition, we identified prospective cohorts of TML patients. Numbers, duration of follow-up, and occurrence of the “testicular tumor” event were recorded for each of them. Results One hundred and seventy-five articles were identified, 40 of which were included. Our review has not showed a clear evidence that cryptorchidism associated with TML is a risk factor for testicular tumor. However, there seems to be a correlation between infertility associated with TML and a higher tumor risk. There were not enough studies to confirm a relationship between family or personal history associated with TML and the tumor risk. There was also a correlation with a higher tumor risk for symptomatic associated with TML and “no given reason for US” plus TML groups. However, these groups are assumed to contain bias and caution must be taken regarding conclusions. Regarding the prospective cohort studies, 16 testicular tumors appeared in the follow-up of patients with TML, 13 patients had risk factors. Conclusion In cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population. © The Author(s). 2018 |
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Testicular microlithiasis and testicular tumor: a review of the literature |
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https://dx.doi.org/10.1186/s12610-018-0073-3 |
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Lagrange, François Lecoanet, Pierre Marçon, Baptiste Eschwege, Pascal Hubert, Jacques |
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