Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India
Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients wi...
Ausführliche Beschreibung
Autor*in: |
Goel, Amit [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2016 |
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Anmerkung: |
© Indian Society of Gastroenterology 2016 |
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Übergeordnetes Werk: |
Enthalten in: Indian Journal of Gastroenterology - Springer-Verlag, 2009, 35(2016), 3 vom: Mai, Seite 216-221 |
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Übergeordnetes Werk: |
volume:35 ; year:2016 ; number:3 ; month:05 ; pages:216-221 |
Links: |
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DOI / URN: |
10.1007/s12664-016-0668-6 |
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Katalog-ID: |
SPR026659778 |
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520 | |a Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. | ||
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10.1007/s12664-016-0668-6 doi (DE-627)SPR026659778 (SPR)s12664-016-0668-6-e DE-627 ger DE-627 rakwb eng Goel, Amit verfasserin aut Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Society of Gastroenterology 2016 Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. Chronic liver disease (dpeaa)DE-He213 Sleep disorders (dpeaa)DE-He213 Sleep-related movement disorders (dpeaa)DE-He213 Jat, Shankar Lal aut Sasi, Avani aut Paliwal, Vimal Kumar aut Aggarwal, Rakesh aut Enthalten in Indian Journal of Gastroenterology Springer-Verlag, 2009 35(2016), 3 vom: Mai, Seite 216-221 (DE-627)SPR02665167X nnns volume:35 year:2016 number:3 month:05 pages:216-221 https://dx.doi.org/10.1007/s12664-016-0668-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2016 3 05 216-221 |
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10.1007/s12664-016-0668-6 doi (DE-627)SPR026659778 (SPR)s12664-016-0668-6-e DE-627 ger DE-627 rakwb eng Goel, Amit verfasserin aut Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Society of Gastroenterology 2016 Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. Chronic liver disease (dpeaa)DE-He213 Sleep disorders (dpeaa)DE-He213 Sleep-related movement disorders (dpeaa)DE-He213 Jat, Shankar Lal aut Sasi, Avani aut Paliwal, Vimal Kumar aut Aggarwal, Rakesh aut Enthalten in Indian Journal of Gastroenterology Springer-Verlag, 2009 35(2016), 3 vom: Mai, Seite 216-221 (DE-627)SPR02665167X nnns volume:35 year:2016 number:3 month:05 pages:216-221 https://dx.doi.org/10.1007/s12664-016-0668-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2016 3 05 216-221 |
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10.1007/s12664-016-0668-6 doi (DE-627)SPR026659778 (SPR)s12664-016-0668-6-e DE-627 ger DE-627 rakwb eng Goel, Amit verfasserin aut Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Society of Gastroenterology 2016 Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. Chronic liver disease (dpeaa)DE-He213 Sleep disorders (dpeaa)DE-He213 Sleep-related movement disorders (dpeaa)DE-He213 Jat, Shankar Lal aut Sasi, Avani aut Paliwal, Vimal Kumar aut Aggarwal, Rakesh aut Enthalten in Indian Journal of Gastroenterology Springer-Verlag, 2009 35(2016), 3 vom: Mai, Seite 216-221 (DE-627)SPR02665167X nnns volume:35 year:2016 number:3 month:05 pages:216-221 https://dx.doi.org/10.1007/s12664-016-0668-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2016 3 05 216-221 |
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10.1007/s12664-016-0668-6 doi (DE-627)SPR026659778 (SPR)s12664-016-0668-6-e DE-627 ger DE-627 rakwb eng Goel, Amit verfasserin aut Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Society of Gastroenterology 2016 Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. Chronic liver disease (dpeaa)DE-He213 Sleep disorders (dpeaa)DE-He213 Sleep-related movement disorders (dpeaa)DE-He213 Jat, Shankar Lal aut Sasi, Avani aut Paliwal, Vimal Kumar aut Aggarwal, Rakesh aut Enthalten in Indian Journal of Gastroenterology Springer-Verlag, 2009 35(2016), 3 vom: Mai, Seite 216-221 (DE-627)SPR02665167X nnns volume:35 year:2016 number:3 month:05 pages:216-221 https://dx.doi.org/10.1007/s12664-016-0668-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2016 3 05 216-221 |
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10.1007/s12664-016-0668-6 doi (DE-627)SPR026659778 (SPR)s12664-016-0668-6-e DE-627 ger DE-627 rakwb eng Goel, Amit verfasserin aut Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Society of Gastroenterology 2016 Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. Chronic liver disease (dpeaa)DE-He213 Sleep disorders (dpeaa)DE-He213 Sleep-related movement disorders (dpeaa)DE-He213 Jat, Shankar Lal aut Sasi, Avani aut Paliwal, Vimal Kumar aut Aggarwal, Rakesh aut Enthalten in Indian Journal of Gastroenterology Springer-Verlag, 2009 35(2016), 3 vom: Mai, Seite 216-221 (DE-627)SPR02665167X nnns volume:35 year:2016 number:3 month:05 pages:216-221 https://dx.doi.org/10.1007/s12664-016-0668-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2016 3 05 216-221 |
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prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in india |
title_auth |
Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India |
abstract |
Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. © Indian Society of Gastroenterology 2016 |
abstractGer |
Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. © Indian Society of Gastroenterology 2016 |
abstract_unstemmed |
Background and Aim Restless leg syndrome (RLS) has recently been shown to be increased in patients with liver cirrhosis (LC). We prospectively studied the prevalence and severity of RLS, and the effect of its presence on the quality of life (QoL) in Indian patients with LC. Methods Adult patients with stable LC (n = 121; 98 male; median age 47 [range 18–68] years; Child-Pugh class A/B/C 59/39/23), were prospectively enrolled along with a group of healthy, adult controls (n = 121; 84 male; median age 42 [19–70] years). Patients with recent (<4 weeks) worsening were excluded. The subjects underwent an initial screening for RLS, followed by a re-evaluation to confirm the diagnosis, using the International RLS Diagnostic Criteria, and assessment of its severity. All participants underwent QoL assessment. Results RLS was commoner in LC patients (8/121; 6.6 %) than in controls (1/121; p < 0.05; odds ratio = 8.5 [1.1–69.0]). Presence of RLS showed no association with specific gender (male 7/98, female 1/23), Child-Pugh class (A 5/59, B 1/39 and C 2/23) or cause of liver disease (alcohol 3/32, hepatitis B 1/18, hepatitis C 3/28, and cryptogenic 1/25). RLS severity was moderate (5), severe (2), or very severe (1). Though QoL scores were lower in patients with LC than in controls, those in patients with and without RLS were similar. Conclusion RLS was commoner in patients with LC than in controls, but did not correlate with liver disease severity and did not adversely influence QoL in LC. © Indian Society of Gastroenterology 2016 |
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title_short |
Prevalence, severity, and impact on quality of life of restless leg syndrome in patients with liver cirrhosis in India |
url |
https://dx.doi.org/10.1007/s12664-016-0668-6 |
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Jat, Shankar Lal Sasi, Avani Paliwal, Vimal Kumar Aggarwal, Rakesh |
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Jat, Shankar Lal Sasi, Avani Paliwal, Vimal Kumar Aggarwal, Rakesh |
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up_date |
2024-07-03T21:59:33.853Z |
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