Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay

Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Chen, Xiao-Feng [verfasserIn] Lin, Jiang-Wei Pan, Tzu-Ming Cao, Min-Jie Shi, Chao-Lan Cai, Qiu-Feng Liu, Guang-Ming

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Rhabdomyolysis Hazardous substance Mouse model

Anmerkung:	© The Author(s) 2015

Übergeordnetes Werk:	Enthalten in: Fisheries science - Tokyo : Springer Japan, 1994, 81(2015), 3 vom: 26. Feb., Seite 551-558
Übergeordnetes Werk:	volume:81 ; year:2015 ; number:3 ; day:26 ; month:02 ; pages:551-558

Links:	Volltext

DOI / URN:	10.1007/s12562-015-0856-9

Katalog-ID:	SPR026732866

Internformat


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520			\|a Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research.
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912			\|a GBV_ILN_224
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912			\|a GBV_ILN_2118
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author_variant	x f c xfc j w l jwl t m p tmp m j c mjc c l s cls q f c qfc g m l gml
matchkey_str	article:14442906:2015----::netgtooteaadusbtneasncafsidcdhboylssiaosmdlhm
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allfields	10.1007/s12562-015-0856-9 doi (DE-627)SPR026732866 (SPR)s12562-015-0856-9-e DE-627 ger DE-627 rakwb eng Chen, Xiao-Feng verfasserin aut Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. Rhabdomyolysis (dpeaa)DE-He213 Hazardous substance (dpeaa)DE-He213 Mouse model (dpeaa)DE-He213 Lin, Jiang-Wei aut Pan, Tzu-Ming aut Cao, Min-Jie aut Shi, Chao-Lan aut Cai, Qiu-Feng aut Liu, Guang-Ming aut Enthalten in Fisheries science Tokyo : Springer Japan, 1994 81(2015), 3 vom: 26. Feb., Seite 551-558 (DE-627)32060215X (DE-600)2020302-0 1444-2906 nnns volume:81 year:2015 number:3 day:26 month:02 pages:551-558 https://dx.doi.org/10.1007/s12562-015-0856-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 81 2015 3 26 02 551-558
spelling	10.1007/s12562-015-0856-9 doi (DE-627)SPR026732866 (SPR)s12562-015-0856-9-e DE-627 ger DE-627 rakwb eng Chen, Xiao-Feng verfasserin aut Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. Rhabdomyolysis (dpeaa)DE-He213 Hazardous substance (dpeaa)DE-He213 Mouse model (dpeaa)DE-He213 Lin, Jiang-Wei aut Pan, Tzu-Ming aut Cao, Min-Jie aut Shi, Chao-Lan aut Cai, Qiu-Feng aut Liu, Guang-Ming aut Enthalten in Fisheries science Tokyo : Springer Japan, 1994 81(2015), 3 vom: 26. Feb., Seite 551-558 (DE-627)32060215X (DE-600)2020302-0 1444-2906 nnns volume:81 year:2015 number:3 day:26 month:02 pages:551-558 https://dx.doi.org/10.1007/s12562-015-0856-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 81 2015 3 26 02 551-558
allfields_unstemmed	10.1007/s12562-015-0856-9 doi (DE-627)SPR026732866 (SPR)s12562-015-0856-9-e DE-627 ger DE-627 rakwb eng Chen, Xiao-Feng verfasserin aut Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. Rhabdomyolysis (dpeaa)DE-He213 Hazardous substance (dpeaa)DE-He213 Mouse model (dpeaa)DE-He213 Lin, Jiang-Wei aut Pan, Tzu-Ming aut Cao, Min-Jie aut Shi, Chao-Lan aut Cai, Qiu-Feng aut Liu, Guang-Ming aut Enthalten in Fisheries science Tokyo : Springer Japan, 1994 81(2015), 3 vom: 26. Feb., Seite 551-558 (DE-627)32060215X (DE-600)2020302-0 1444-2906 nnns volume:81 year:2015 number:3 day:26 month:02 pages:551-558 https://dx.doi.org/10.1007/s12562-015-0856-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 81 2015 3 26 02 551-558
allfieldsGer	10.1007/s12562-015-0856-9 doi (DE-627)SPR026732866 (SPR)s12562-015-0856-9-e DE-627 ger DE-627 rakwb eng Chen, Xiao-Feng verfasserin aut Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. Rhabdomyolysis (dpeaa)DE-He213 Hazardous substance (dpeaa)DE-He213 Mouse model (dpeaa)DE-He213 Lin, Jiang-Wei aut Pan, Tzu-Ming aut Cao, Min-Jie aut Shi, Chao-Lan aut Cai, Qiu-Feng aut Liu, Guang-Ming aut Enthalten in Fisheries science Tokyo : Springer Japan, 1994 81(2015), 3 vom: 26. Feb., Seite 551-558 (DE-627)32060215X (DE-600)2020302-0 1444-2906 nnns volume:81 year:2015 number:3 day:26 month:02 pages:551-558 https://dx.doi.org/10.1007/s12562-015-0856-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 81 2015 3 26 02 551-558
allfieldsSound	10.1007/s12562-015-0856-9 doi (DE-627)SPR026732866 (SPR)s12562-015-0856-9-e DE-627 ger DE-627 rakwb eng Chen, Xiao-Feng verfasserin aut Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. Rhabdomyolysis (dpeaa)DE-He213 Hazardous substance (dpeaa)DE-He213 Mouse model (dpeaa)DE-He213 Lin, Jiang-Wei aut Pan, Tzu-Ming aut Cao, Min-Jie aut Shi, Chao-Lan aut Cai, Qiu-Feng aut Liu, Guang-Ming aut Enthalten in Fisheries science Tokyo : Springer Japan, 1994 81(2015), 3 vom: 26. Feb., Seite 551-558 (DE-627)32060215X (DE-600)2020302-0 1444-2906 nnns volume:81 year:2015 number:3 day:26 month:02 pages:551-558 https://dx.doi.org/10.1007/s12562-015-0856-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 81 2015 3 26 02 551-558
language	English
source	Enthalten in Fisheries science 81(2015), 3 vom: 26. Feb., Seite 551-558 volume:81 year:2015 number:3 day:26 month:02 pages:551-558
sourceStr	Enthalten in Fisheries science 81(2015), 3 vom: 26. Feb., Seite 551-558 volume:81 year:2015 number:3 day:26 month:02 pages:551-558
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Rhabdomyolysis Hazardous substance Mouse model
isfreeaccess_bool	true
container_title	Fisheries science
authorswithroles_txt_mv	Chen, Xiao-Feng @@aut@@ Lin, Jiang-Wei @@aut@@ Pan, Tzu-Ming @@aut@@ Cao, Min-Jie @@aut@@ Shi, Chao-Lan @@aut@@ Cai, Qiu-Feng @@aut@@ Liu, Guang-Ming @@aut@@
publishDateDaySort_date	2015-02-26T00:00:00Z
hierarchy_top_id	32060215X
id	SPR026732866
language_de	englisch
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author	Chen, Xiao-Feng
spellingShingle	Chen, Xiao-Feng misc Rhabdomyolysis misc Hazardous substance misc Mouse model Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay
authorStr	Chen, Xiao-Feng
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topic_title	Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay Rhabdomyolysis (dpeaa)DE-He213 Hazardous substance (dpeaa)DE-He213 Mouse model (dpeaa)DE-He213
topic	misc Rhabdomyolysis misc Hazardous substance misc Mouse model
topic_unstemmed	misc Rhabdomyolysis misc Hazardous substance misc Mouse model
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title	Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay
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title_full	Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay
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author_browse	Chen, Xiao-Feng Lin, Jiang-Wei Pan, Tzu-Ming Cao, Min-Jie Shi, Chao-Lan Cai, Qiu-Feng Liu, Guang-Ming
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author-letter	Chen, Xiao-Feng
doi_str_mv	10.1007/s12562-015-0856-9
title_sort	investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay
title_auth	Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay
abstract	Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. © The Author(s) 2015
abstractGer	Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. © The Author(s) 2015
abstract_unstemmed	Abstract The hazardous substance from Procambarus clarkii could cause rhabdomyolysis. Mice were administered mashed muscles and gills, intestines, and glands (GIG) obtained from cooked crayfish by gavage . Three of seventy-two mice administered with GIG (with an incidence rate of 4.17 %) appeared to have rhabdomyolysis symptoms with the serum creatine kinase (CK) content increased by more than 5 times, as well as the pathological changes in livers, spleens, kidneys, and skeletal muscles. Furthermore, the cytotoxicity and hemolysis analysis of the palytoxin revealed that the methanol/water extracts from GIG of crayfish were not inhibited by ouabain effectively, which pointed out the hazardous substance causing rhabdomyolysis was not allergen or palytoxin. These research results could be valuable in further comprehensive experiments and lay a foundation for basic rhabdomyolysis research. © The Author(s) 2015
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title_short	Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay
url	https://dx.doi.org/10.1007/s12562-015-0856-9
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author2	Lin, Jiang-Wei Pan, Tzu-Ming Cao, Min-Jie Shi, Chao-Lan Cai, Qiu-Feng Liu, Guang-Ming
author2Str	Lin, Jiang-Wei Pan, Tzu-Ming Cao, Min-Jie Shi, Chao-Lan Cai, Qiu-Feng Liu, Guang-Ming
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doi_str	10.1007/s12562-015-0856-9
up_date	2024-07-03T22:27:17.685Z
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Investigation of the hazardous substance causing crayfish-induced rhabdomyolysis via a mouse model, a hemolysis assay, and a cytotoxicity assay

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