Platelet indices and outcome after cardiac arrest

Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care un...
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Autor*in:	Cotoia, Antonella [verfasserIn] Franchi, Federico De Fazio, Chiara Vincent, Jean-Louis Creteur, Jacques Taccone, Fabio Silvio

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Platelet distribution width Cardiac arrest Hypothermia Platelet indices

Anmerkung:	© The Author(s). 2018

Übergeordnetes Werk:	Enthalten in: BMC emergency medicine - London : BioMed Central, 2001, 18(2018), 1 vom: 25. Sept.
Übergeordnetes Werk:	volume:18 ; year:2018 ; number:1 ; day:25 ; month:09

Links:	Volltext

DOI / URN:	10.1186/s12873-018-0183-4

Katalog-ID:	SPR027356124

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520			\|a Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome.
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allfields	10.1186/s12873-018-0183-4 doi (DE-627)SPR027356124 (SPR)s12873-018-0183-4-e DE-627 ger DE-627 rakwb eng Cotoia, Antonella verfasserin aut Platelet indices and outcome after cardiac arrest 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. Platelet distribution width (dpeaa)DE-He213 Cardiac arrest (dpeaa)DE-He213 Hypothermia (dpeaa)DE-He213 Platelet indices (dpeaa)DE-He213 Franchi, Federico aut De Fazio, Chiara aut Vincent, Jean-Louis aut Creteur, Jacques aut Taccone, Fabio Silvio aut Enthalten in BMC emergency medicine London : BioMed Central, 2001 18(2018), 1 vom: 25. Sept. (DE-627)33101873X (DE-600)2050431-7 1471-227X nnns volume:18 year:2018 number:1 day:25 month:09 https://dx.doi.org/10.1186/s12873-018-0183-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2018 1 25 09
spelling	10.1186/s12873-018-0183-4 doi (DE-627)SPR027356124 (SPR)s12873-018-0183-4-e DE-627 ger DE-627 rakwb eng Cotoia, Antonella verfasserin aut Platelet indices and outcome after cardiac arrest 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. Platelet distribution width (dpeaa)DE-He213 Cardiac arrest (dpeaa)DE-He213 Hypothermia (dpeaa)DE-He213 Platelet indices (dpeaa)DE-He213 Franchi, Federico aut De Fazio, Chiara aut Vincent, Jean-Louis aut Creteur, Jacques aut Taccone, Fabio Silvio aut Enthalten in BMC emergency medicine London : BioMed Central, 2001 18(2018), 1 vom: 25. Sept. (DE-627)33101873X (DE-600)2050431-7 1471-227X nnns volume:18 year:2018 number:1 day:25 month:09 https://dx.doi.org/10.1186/s12873-018-0183-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2018 1 25 09
allfields_unstemmed	10.1186/s12873-018-0183-4 doi (DE-627)SPR027356124 (SPR)s12873-018-0183-4-e DE-627 ger DE-627 rakwb eng Cotoia, Antonella verfasserin aut Platelet indices and outcome after cardiac arrest 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. Platelet distribution width (dpeaa)DE-He213 Cardiac arrest (dpeaa)DE-He213 Hypothermia (dpeaa)DE-He213 Platelet indices (dpeaa)DE-He213 Franchi, Federico aut De Fazio, Chiara aut Vincent, Jean-Louis aut Creteur, Jacques aut Taccone, Fabio Silvio aut Enthalten in BMC emergency medicine London : BioMed Central, 2001 18(2018), 1 vom: 25. Sept. (DE-627)33101873X (DE-600)2050431-7 1471-227X nnns volume:18 year:2018 number:1 day:25 month:09 https://dx.doi.org/10.1186/s12873-018-0183-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2018 1 25 09
allfieldsGer	10.1186/s12873-018-0183-4 doi (DE-627)SPR027356124 (SPR)s12873-018-0183-4-e DE-627 ger DE-627 rakwb eng Cotoia, Antonella verfasserin aut Platelet indices and outcome after cardiac arrest 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. Platelet distribution width (dpeaa)DE-He213 Cardiac arrest (dpeaa)DE-He213 Hypothermia (dpeaa)DE-He213 Platelet indices (dpeaa)DE-He213 Franchi, Federico aut De Fazio, Chiara aut Vincent, Jean-Louis aut Creteur, Jacques aut Taccone, Fabio Silvio aut Enthalten in BMC emergency medicine London : BioMed Central, 2001 18(2018), 1 vom: 25. Sept. (DE-627)33101873X (DE-600)2050431-7 1471-227X nnns volume:18 year:2018 number:1 day:25 month:09 https://dx.doi.org/10.1186/s12873-018-0183-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2018 1 25 09
allfieldsSound	10.1186/s12873-018-0183-4 doi (DE-627)SPR027356124 (SPR)s12873-018-0183-4-e DE-627 ger DE-627 rakwb eng Cotoia, Antonella verfasserin aut Platelet indices and outcome after cardiac arrest 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. Platelet distribution width (dpeaa)DE-He213 Cardiac arrest (dpeaa)DE-He213 Hypothermia (dpeaa)DE-He213 Platelet indices (dpeaa)DE-He213 Franchi, Federico aut De Fazio, Chiara aut Vincent, Jean-Louis aut Creteur, Jacques aut Taccone, Fabio Silvio aut Enthalten in BMC emergency medicine London : BioMed Central, 2001 18(2018), 1 vom: 25. Sept. (DE-627)33101873X (DE-600)2050431-7 1471-227X nnns volume:18 year:2018 number:1 day:25 month:09 https://dx.doi.org/10.1186/s12873-018-0183-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2018 1 25 09
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source	Enthalten in BMC emergency medicine 18(2018), 1 vom: 25. Sept. volume:18 year:2018 number:1 day:25 month:09
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We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. 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author	Cotoia, Antonella
spellingShingle	Cotoia, Antonella misc Platelet distribution width misc Cardiac arrest misc Hypothermia misc Platelet indices Platelet indices and outcome after cardiac arrest
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topic_title	Platelet indices and outcome after cardiac arrest Platelet distribution width (dpeaa)DE-He213 Cardiac arrest (dpeaa)DE-He213 Hypothermia (dpeaa)DE-He213 Platelet indices (dpeaa)DE-He213
topic	misc Platelet distribution width misc Cardiac arrest misc Hypothermia misc Platelet indices
topic_unstemmed	misc Platelet distribution width misc Cardiac arrest misc Hypothermia misc Platelet indices
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title	Platelet indices and outcome after cardiac arrest
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title_full	Platelet indices and outcome after cardiac arrest
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author_browse	Cotoia, Antonella Franchi, Federico De Fazio, Chiara Vincent, Jean-Louis Creteur, Jacques Taccone, Fabio Silvio
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author-letter	Cotoia, Antonella
doi_str_mv	10.1186/s12873-018-0183-4
title_sort	platelet indices and outcome after cardiac arrest
title_auth	Platelet indices and outcome after cardiac arrest
abstract	Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. © The Author(s). 2018
abstractGer	Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. © The Author(s). 2018
abstract_unstemmed	Background Platelet variables, including platelet distribution width (PDW) and mean platelet volume (MPV), have been associated with outcome in critically ill patients. We evaluated these variables in patients after cardiac arrest (CA). Methods All adult CA patients admitted to the intensive care unit (ICU) over an 8-year period (2006–2014) and treated with targeted temperature management were included. We retrieved all data concerning CA characteristics as well as platelet count, PDW and MPV on the first 2 days of admission. Unfavorable 3-month neurological outcome was defined as a cerebral performance category score of 3–5. Results We included 384 patients (age 62 [52–75] years; 270/384 male): 231 patients (60%) died within 30-days and 246 patients (64%) had an unfavorable 3-month neurological outcome. On admission, platelet count, PDW and MPV were 87 [126–261] *$ 10^{3} $cells/$ mm^{3} $, 17 [16.3–17.3]% and 8.3 [7.6–9.2] $ μm^{3} $, respectively. Platelet count decreased significantly over the first 2 days, whereas PDW and MPV did not change significantly. There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. Conclusions In our cohort of post-CA patients, PDW and MPV were not associated with outcome. © The Author(s). 2018
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title_short	Platelet indices and outcome after cardiac arrest
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author2	Franchi, Federico De Fazio, Chiara Vincent, Jean-Louis Creteur, Jacques Taccone, Fabio Silvio
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up_date	2024-07-04T01:30:23.845Z
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There were no significant differences between the values on admission or time-courses of platelet count, PDW or MPV between survivors and non-survivors or between patients with unfavorable and favorable neurological outcome. 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Platelet indices and outcome after cardiac arrest

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