Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study

Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characterist...
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Autor*in:	Bauserman, Melissa [verfasserIn] Nathan, Robert Lokangaka, Adrien McClure, Elizabeth M. Moore, Janet Ishoso, Daniel Tshefu, Antoinette Figueroa, Lester Garces, Ana Harrison, Margo S. Wallace, Dennis Saleem, Sarah Mirza, Waseem Krebs, Nancy Hambidge, Michael Carlo, Waldemar Chomba, Elwyn Miodovnik, Menachem Koso-Thomas, Marion Liechty, Edward A. Esamai, Fabian Swanson, Jonathan Swanson, David Goldenberg, Robert L. Bose, Carl

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Polyhydramnios Low-income country Global health

Anmerkung:	© The Author(s). 2019

Übergeordnetes Werk:	Enthalten in: BMC pregnancy and childbirth - London : BioMed Central, 2001, 19(2019), 1 vom: 22. Juli
Übergeordnetes Werk:	volume:19 ; year:2019 ; number:1 ; day:22 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s12884-019-2412-6

Katalog-ID:	SPR027598268

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520			\|a Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013.
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700	1		\|a Ishoso, Daniel \|4 aut
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allfields	10.1186/s12884-019-2412-6 doi (DE-627)SPR027598268 (SPR)s12884-019-2412-6-e DE-627 ger DE-627 rakwb eng Bauserman, Melissa verfasserin (orcid)0000-0002-4992-9895 aut Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. Polyhydramnios (dpeaa)DE-He213 Low-income country (dpeaa)DE-He213 Global health (dpeaa)DE-He213 Nathan, Robert aut Lokangaka, Adrien aut McClure, Elizabeth M. aut Moore, Janet aut Ishoso, Daniel aut Tshefu, Antoinette aut Figueroa, Lester aut Garces, Ana aut Harrison, Margo S. aut Wallace, Dennis aut Saleem, Sarah aut Mirza, Waseem aut Krebs, Nancy aut Hambidge, Michael aut Carlo, Waldemar aut Chomba, Elwyn aut Miodovnik, Menachem aut Koso-Thomas, Marion aut Liechty, Edward A. aut Esamai, Fabian aut Swanson, Jonathan aut Swanson, David aut Goldenberg, Robert L. aut Bose, Carl aut Enthalten in BMC pregnancy and childbirth London : BioMed Central, 2001 19(2019), 1 vom: 22. Juli (DE-627)335489087 (DE-600)2059869-5 1471-2393 nnns volume:19 year:2019 number:1 day:22 month:07 https://dx.doi.org/10.1186/s12884-019-2412-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 22 07
spelling	10.1186/s12884-019-2412-6 doi (DE-627)SPR027598268 (SPR)s12884-019-2412-6-e DE-627 ger DE-627 rakwb eng Bauserman, Melissa verfasserin (orcid)0000-0002-4992-9895 aut Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. Polyhydramnios (dpeaa)DE-He213 Low-income country (dpeaa)DE-He213 Global health (dpeaa)DE-He213 Nathan, Robert aut Lokangaka, Adrien aut McClure, Elizabeth M. aut Moore, Janet aut Ishoso, Daniel aut Tshefu, Antoinette aut Figueroa, Lester aut Garces, Ana aut Harrison, Margo S. aut Wallace, Dennis aut Saleem, Sarah aut Mirza, Waseem aut Krebs, Nancy aut Hambidge, Michael aut Carlo, Waldemar aut Chomba, Elwyn aut Miodovnik, Menachem aut Koso-Thomas, Marion aut Liechty, Edward A. aut Esamai, Fabian aut Swanson, Jonathan aut Swanson, David aut Goldenberg, Robert L. aut Bose, Carl aut Enthalten in BMC pregnancy and childbirth London : BioMed Central, 2001 19(2019), 1 vom: 22. Juli (DE-627)335489087 (DE-600)2059869-5 1471-2393 nnns volume:19 year:2019 number:1 day:22 month:07 https://dx.doi.org/10.1186/s12884-019-2412-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 22 07
allfields_unstemmed	10.1186/s12884-019-2412-6 doi (DE-627)SPR027598268 (SPR)s12884-019-2412-6-e DE-627 ger DE-627 rakwb eng Bauserman, Melissa verfasserin (orcid)0000-0002-4992-9895 aut Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. Polyhydramnios (dpeaa)DE-He213 Low-income country (dpeaa)DE-He213 Global health (dpeaa)DE-He213 Nathan, Robert aut Lokangaka, Adrien aut McClure, Elizabeth M. aut Moore, Janet aut Ishoso, Daniel aut Tshefu, Antoinette aut Figueroa, Lester aut Garces, Ana aut Harrison, Margo S. aut Wallace, Dennis aut Saleem, Sarah aut Mirza, Waseem aut Krebs, Nancy aut Hambidge, Michael aut Carlo, Waldemar aut Chomba, Elwyn aut Miodovnik, Menachem aut Koso-Thomas, Marion aut Liechty, Edward A. aut Esamai, Fabian aut Swanson, Jonathan aut Swanson, David aut Goldenberg, Robert L. aut Bose, Carl aut Enthalten in BMC pregnancy and childbirth London : BioMed Central, 2001 19(2019), 1 vom: 22. Juli (DE-627)335489087 (DE-600)2059869-5 1471-2393 nnns volume:19 year:2019 number:1 day:22 month:07 https://dx.doi.org/10.1186/s12884-019-2412-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 22 07
allfieldsGer	10.1186/s12884-019-2412-6 doi (DE-627)SPR027598268 (SPR)s12884-019-2412-6-e DE-627 ger DE-627 rakwb eng Bauserman, Melissa verfasserin (orcid)0000-0002-4992-9895 aut Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. Polyhydramnios (dpeaa)DE-He213 Low-income country (dpeaa)DE-He213 Global health (dpeaa)DE-He213 Nathan, Robert aut Lokangaka, Adrien aut McClure, Elizabeth M. aut Moore, Janet aut Ishoso, Daniel aut Tshefu, Antoinette aut Figueroa, Lester aut Garces, Ana aut Harrison, Margo S. aut Wallace, Dennis aut Saleem, Sarah aut Mirza, Waseem aut Krebs, Nancy aut Hambidge, Michael aut Carlo, Waldemar aut Chomba, Elwyn aut Miodovnik, Menachem aut Koso-Thomas, Marion aut Liechty, Edward A. aut Esamai, Fabian aut Swanson, Jonathan aut Swanson, David aut Goldenberg, Robert L. aut Bose, Carl aut Enthalten in BMC pregnancy and childbirth London : BioMed Central, 2001 19(2019), 1 vom: 22. Juli (DE-627)335489087 (DE-600)2059869-5 1471-2393 nnns volume:19 year:2019 number:1 day:22 month:07 https://dx.doi.org/10.1186/s12884-019-2412-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 22 07
allfieldsSound	10.1186/s12884-019-2412-6 doi (DE-627)SPR027598268 (SPR)s12884-019-2412-6-e DE-627 ger DE-627 rakwb eng Bauserman, Melissa verfasserin (orcid)0000-0002-4992-9895 aut Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. Polyhydramnios (dpeaa)DE-He213 Low-income country (dpeaa)DE-He213 Global health (dpeaa)DE-He213 Nathan, Robert aut Lokangaka, Adrien aut McClure, Elizabeth M. aut Moore, Janet aut Ishoso, Daniel aut Tshefu, Antoinette aut Figueroa, Lester aut Garces, Ana aut Harrison, Margo S. aut Wallace, Dennis aut Saleem, Sarah aut Mirza, Waseem aut Krebs, Nancy aut Hambidge, Michael aut Carlo, Waldemar aut Chomba, Elwyn aut Miodovnik, Menachem aut Koso-Thomas, Marion aut Liechty, Edward A. aut Esamai, Fabian aut Swanson, Jonathan aut Swanson, David aut Goldenberg, Robert L. aut Bose, Carl aut Enthalten in BMC pregnancy and childbirth London : BioMed Central, 2001 19(2019), 1 vom: 22. Juli (DE-627)335489087 (DE-600)2059869-5 1471-2393 nnns volume:19 year:2019 number:1 day:22 month:07 https://dx.doi.org/10.1186/s12884-019-2412-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 22 07
language	English
source	Enthalten in BMC pregnancy and childbirth 19(2019), 1 vom: 22. Juli volume:19 year:2019 number:1 day:22 month:07
sourceStr	Enthalten in BMC pregnancy and childbirth 19(2019), 1 vom: 22. Juli volume:19 year:2019 number:1 day:22 month:07
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Polyhydramnios Low-income country Global health
isfreeaccess_bool	true
container_title	BMC pregnancy and childbirth
authorswithroles_txt_mv	Bauserman, Melissa @@aut@@ Nathan, Robert @@aut@@ Lokangaka, Adrien @@aut@@ McClure, Elizabeth M. @@aut@@ Moore, Janet @@aut@@ Ishoso, Daniel @@aut@@ Tshefu, Antoinette @@aut@@ Figueroa, Lester @@aut@@ Garces, Ana @@aut@@ Harrison, Margo S. @@aut@@ Wallace, Dennis @@aut@@ Saleem, Sarah @@aut@@ Mirza, Waseem @@aut@@ Krebs, Nancy @@aut@@ Hambidge, Michael @@aut@@ Carlo, Waldemar @@aut@@ Chomba, Elwyn @@aut@@ Miodovnik, Menachem @@aut@@ Koso-Thomas, Marion @@aut@@ Liechty, Edward A. @@aut@@ Esamai, Fabian @@aut@@ Swanson, Jonathan @@aut@@ Swanson, David @@aut@@ Goldenberg, Robert L. @@aut@@ Bose, Carl @@aut@@
publishDateDaySort_date	2019-07-22T00:00:00Z
hierarchy_top_id	335489087
id	SPR027598268
language_de	englisch
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A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. 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author	Bauserman, Melissa
spellingShingle	Bauserman, Melissa misc Polyhydramnios misc Low-income country misc Global health Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study
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topic_title	Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study Polyhydramnios (dpeaa)DE-He213 Low-income country (dpeaa)DE-He213 Global health (dpeaa)DE-He213
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title	Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study
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title_full	Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study
author_sort	Bauserman, Melissa
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author_browse	Bauserman, Melissa Nathan, Robert Lokangaka, Adrien McClure, Elizabeth M. Moore, Janet Ishoso, Daniel Tshefu, Antoinette Figueroa, Lester Garces, Ana Harrison, Margo S. Wallace, Dennis Saleem, Sarah Mirza, Waseem Krebs, Nancy Hambidge, Michael Carlo, Waldemar Chomba, Elwyn Miodovnik, Menachem Koso-Thomas, Marion Liechty, Edward A. Esamai, Fabian Swanson, Jonathan Swanson, David Goldenberg, Robert L. Bose, Carl
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title_sort	polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study
title_auth	Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study
abstract	Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. © The Author(s). 2019
abstractGer	Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. © The Author(s). 2019
abstract_unstemmed	Background In many low and low-middle income countries, the incidence of polyhydramnios is unknown, in part because ultrasound technology is not routinely used. Our objective was to report the incidence of polyhydramnios in five low and low-middle income countries, to determine maternal characteristics associated with polyhydramnios, and report pregnancy and neonatal outcomes. Methods We performed a secondary analysis of the First Look Study, a multi-national, cluster-randomized trial of ultrasound during prenatal care. We evaluated all women enrolled from Guatemala, Pakistan, Zambia, Kenya and the Democratic Republic of Congo (DRC) who received an examination by prenatal ultrasound. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models with general estimating equations to control for cluster-level effects. The diagnosis of polyhydramnios was confrimed by an U.S. based radiologist in a majority of cases (62%). Results We identified 305/18,640 (1.6%) cases of polyhydramnios. 229 (75%) cases were from the DRC, with an incidence of 10%. A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. Trial registration NCT01990625, November 21, 2013. © The Author(s). 2019
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title_short	Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study
url	https://dx.doi.org/10.1186/s12884-019-2412-6
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author2	Nathan, Robert Lokangaka, Adrien McClure, Elizabeth M. Moore, Janet Ishoso, Daniel Tshefu, Antoinette Figueroa, Lester Garces, Ana Harrison, Margo S. Wallace, Dennis Saleem, Sarah Mirza, Waseem Krebs, Nancy Hambidge, Michael Carlo, Waldemar Chomba, Elwyn Miodovnik, Menachem Koso-Thomas, Marion Liechty, Edward A. Esamai, Fabian Swanson, Jonathan Swanson, David Goldenberg, Robert L. Bose, Carl
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A higher percentage of women with polyhydramnios experienced obstructed labor (7% vs 4%) and fetal malposition (4% vs 2%). Neonatal death was more common when polyhydramnios was present (OR 2.43; CI 1.15, 5.13). Conclusions Polyhydramnios occured in these low and low-middle income countries at a rate similar to high-income contries except in the DRC where the incidence was 10%. Polyhydramnios was associated with obstructed labor, fetal malposition, and neonatal death. 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Polyhydramnios among women in a cluster-randomized trial of ultrasound during prenatal care within five low and low-middle income countries: a secondary analysis of the first look study

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