Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China

Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Me...
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Autor*in:	Yang, Ya [verfasserIn] Wang, Yingjian Yang, Dongjian Dong, Shurong Yang, Yu Zhu, Xu Chen, Yue Zhou, Yibiao Jiang, Qingwu

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	vaccine Coverage Timeliness Completion

Anmerkung:	© The Author(s). 2019

Übergeordnetes Werk:	Enthalten in: BMC pediatrics - London : BioMed Central, 2001, 19(2019), 1 vom: 07. Jan.
Übergeordnetes Werk:	volume:19 ; year:2019 ; number:1 ; day:07 ; month:01

Links:	Volltext

DOI / URN:	10.1186/s12887-018-1374-6

Katalog-ID:	SPR027770478

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520			\|a Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines.
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allfields	10.1186/s12887-018-1374-6 doi (DE-627)SPR027770478 (SPR)s12887-018-1374-6-e DE-627 ger DE-627 rakwb eng Yang, Ya verfasserin aut Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. vaccine (dpeaa)DE-He213 Coverage (dpeaa)DE-He213 Timeliness (dpeaa)DE-He213 Completion (dpeaa)DE-He213 Wang, Yingjian aut Yang, Dongjian aut Dong, Shurong aut Yang, Yu aut Zhu, Xu aut Chen, Yue aut Zhou, Yibiao (orcid)0000-0002-4635-0802 aut Jiang, Qingwu aut Enthalten in BMC pediatrics London : BioMed Central, 2001 19(2019), 1 vom: 07. Jan. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:19 year:2019 number:1 day:07 month:01 https://dx.doi.org/10.1186/s12887-018-1374-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 07 01
spelling	10.1186/s12887-018-1374-6 doi (DE-627)SPR027770478 (SPR)s12887-018-1374-6-e DE-627 ger DE-627 rakwb eng Yang, Ya verfasserin aut Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. vaccine (dpeaa)DE-He213 Coverage (dpeaa)DE-He213 Timeliness (dpeaa)DE-He213 Completion (dpeaa)DE-He213 Wang, Yingjian aut Yang, Dongjian aut Dong, Shurong aut Yang, Yu aut Zhu, Xu aut Chen, Yue aut Zhou, Yibiao (orcid)0000-0002-4635-0802 aut Jiang, Qingwu aut Enthalten in BMC pediatrics London : BioMed Central, 2001 19(2019), 1 vom: 07. Jan. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:19 year:2019 number:1 day:07 month:01 https://dx.doi.org/10.1186/s12887-018-1374-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 07 01
allfields_unstemmed	10.1186/s12887-018-1374-6 doi (DE-627)SPR027770478 (SPR)s12887-018-1374-6-e DE-627 ger DE-627 rakwb eng Yang, Ya verfasserin aut Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. vaccine (dpeaa)DE-He213 Coverage (dpeaa)DE-He213 Timeliness (dpeaa)DE-He213 Completion (dpeaa)DE-He213 Wang, Yingjian aut Yang, Dongjian aut Dong, Shurong aut Yang, Yu aut Zhu, Xu aut Chen, Yue aut Zhou, Yibiao (orcid)0000-0002-4635-0802 aut Jiang, Qingwu aut Enthalten in BMC pediatrics London : BioMed Central, 2001 19(2019), 1 vom: 07. Jan. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:19 year:2019 number:1 day:07 month:01 https://dx.doi.org/10.1186/s12887-018-1374-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 07 01
allfieldsGer	10.1186/s12887-018-1374-6 doi (DE-627)SPR027770478 (SPR)s12887-018-1374-6-e DE-627 ger DE-627 rakwb eng Yang, Ya verfasserin aut Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. vaccine (dpeaa)DE-He213 Coverage (dpeaa)DE-He213 Timeliness (dpeaa)DE-He213 Completion (dpeaa)DE-He213 Wang, Yingjian aut Yang, Dongjian aut Dong, Shurong aut Yang, Yu aut Zhu, Xu aut Chen, Yue aut Zhou, Yibiao (orcid)0000-0002-4635-0802 aut Jiang, Qingwu aut Enthalten in BMC pediatrics London : BioMed Central, 2001 19(2019), 1 vom: 07. Jan. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:19 year:2019 number:1 day:07 month:01 https://dx.doi.org/10.1186/s12887-018-1374-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 07 01
allfieldsSound	10.1186/s12887-018-1374-6 doi (DE-627)SPR027770478 (SPR)s12887-018-1374-6-e DE-627 ger DE-627 rakwb eng Yang, Ya verfasserin aut Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2019 Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. vaccine (dpeaa)DE-He213 Coverage (dpeaa)DE-He213 Timeliness (dpeaa)DE-He213 Completion (dpeaa)DE-He213 Wang, Yingjian aut Yang, Dongjian aut Dong, Shurong aut Yang, Yu aut Zhu, Xu aut Chen, Yue aut Zhou, Yibiao (orcid)0000-0002-4635-0802 aut Jiang, Qingwu aut Enthalten in BMC pediatrics London : BioMed Central, 2001 19(2019), 1 vom: 07. Jan. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:19 year:2019 number:1 day:07 month:01 https://dx.doi.org/10.1186/s12887-018-1374-6 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 07 01
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spellingShingle	Yang, Ya misc vaccine misc Coverage misc Timeliness misc Completion Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China
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topic_title	Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China vaccine (dpeaa)DE-He213 Coverage (dpeaa)DE-He213 Timeliness (dpeaa)DE-He213 Completion (dpeaa)DE-He213
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title	Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China
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title_full	Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China
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author_browse	Yang, Ya Wang, Yingjian Yang, Dongjian Dong, Shurong Yang, Yu Zhu, Xu Chen, Yue Zhou, Yibiao Jiang, Qingwu
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title_sort	factors associated with uptake of haemophilus influenzae type b vaccination in shanghai, china
title_auth	Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China
abstract	Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. © The Author(s). 2019
abstractGer	Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. © The Author(s). 2019
abstract_unstemmed	Background Haemophilus influenzae type b (Hib) vaccine is effective in reducing the burden of Hib related diseases, but little is known about factors influencing the uptake of Hib vaccine. This study aimed to assess the uptake of Hib vaccination and its associated factors in Shanghai City, China. Methods We used data from a retrospective cohort of 183,246 children born in 2012–2016 obtained from the Shanghai Immunization Program Information System, which provided information on the uptake of Hib vaccination. We conducted a cross-sectional study of 451 children to collect information on demographic and other factors that might be associated with Hib vaccination. Results In the retrospective cohort study, the proportions of Hib dose-1 coverage, vaccination completion and timeliness were 67.7, 52.2 and 29.4%, respectively. These measures were better among local children and increased with birth year, while there were regional differences. Hib vaccine uptake was significantly associated with maternal occupation (non-health vs health workers, OR = 2.33, 95% CI: 1.32–4.13, P = 0.004) and caregivers’ awareness of Hib (yes vs no, OR = 1.75, 95% CI: 1.12–2.74, P = 0.013). Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. The inclusion of Hib vaccine into the national immunization program could help improve the uptake of Hib vaccines. © The Author(s). 2019
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title_short	Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China
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author2	Wang, Yingjian Yang, Dongjian Dong, Shurong Yang, Yu Zhu, Xu Chen, Yue Zhou, Yibiao Jiang, Qingwu
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Conclusions We found low levels of coverage of dose-1 Hib vaccine, timeliness and completion, suggesting inadequate protection against Hib disease for children in Shanghai. Non-local children and those of health workers should be targeted for interventions. 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Factors associated with uptake of Haemophilus influenzae type b vaccination in Shanghai, China

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