Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study

Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, a...
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Autor*in:	Anand, Sonia S [verfasserIn] Vasudevan, Anil Gupta, Milan Morrison, Katherine Kurpad, Anura Teo, Koon K Srinivasan, Krishnamachari

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Birth cohort South Asian Adiposity Insulin resistance Early origins India Canada

Anmerkung:	© Anand et al; licensee BioMed Central Ltd. 2013

Übergeordnetes Werk:	Enthalten in: BMC public health - London : BioMed Central, 2001, 13(2013), 1 vom: 28. Jan.
Übergeordnetes Werk:	volume:13 ; year:2013 ; number:1 ; day:28 ; month:01

Links:	Volltext

DOI / URN:	10.1186/1471-2458-13-79

Katalog-ID:	SPR027877787

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520			\|a Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada.
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allfields	10.1186/1471-2458-13-79 doi (DE-627)SPR027877787 (SPR)1471-2458-13-79-e DE-627 ger DE-627 rakwb eng Anand, Sonia S verfasserin aut Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Anand et al; licensee BioMed Central Ltd. 2013 Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. Birth cohort (dpeaa)DE-He213 South Asian (dpeaa)DE-He213 Adiposity (dpeaa)DE-He213 Insulin resistance (dpeaa)DE-He213 Early origins (dpeaa)DE-He213 India (dpeaa)DE-He213 Canada (dpeaa)DE-He213 Vasudevan, Anil aut Gupta, Milan aut Morrison, Katherine aut Kurpad, Anura aut Teo, Koon K aut Srinivasan, Krishnamachari aut Enthalten in BMC public health London : BioMed Central, 2001 13(2013), 1 vom: 28. Jan. (DE-627)326643583 (DE-600)2041338-5 1471-2458 nnns volume:13 year:2013 number:1 day:28 month:01 https://dx.doi.org/10.1186/1471-2458-13-79 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 1 28 01
spelling	10.1186/1471-2458-13-79 doi (DE-627)SPR027877787 (SPR)1471-2458-13-79-e DE-627 ger DE-627 rakwb eng Anand, Sonia S verfasserin aut Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Anand et al; licensee BioMed Central Ltd. 2013 Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. Birth cohort (dpeaa)DE-He213 South Asian (dpeaa)DE-He213 Adiposity (dpeaa)DE-He213 Insulin resistance (dpeaa)DE-He213 Early origins (dpeaa)DE-He213 India (dpeaa)DE-He213 Canada (dpeaa)DE-He213 Vasudevan, Anil aut Gupta, Milan aut Morrison, Katherine aut Kurpad, Anura aut Teo, Koon K aut Srinivasan, Krishnamachari aut Enthalten in BMC public health London : BioMed Central, 2001 13(2013), 1 vom: 28. Jan. (DE-627)326643583 (DE-600)2041338-5 1471-2458 nnns volume:13 year:2013 number:1 day:28 month:01 https://dx.doi.org/10.1186/1471-2458-13-79 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 1 28 01
allfields_unstemmed	10.1186/1471-2458-13-79 doi (DE-627)SPR027877787 (SPR)1471-2458-13-79-e DE-627 ger DE-627 rakwb eng Anand, Sonia S verfasserin aut Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Anand et al; licensee BioMed Central Ltd. 2013 Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. Birth cohort (dpeaa)DE-He213 South Asian (dpeaa)DE-He213 Adiposity (dpeaa)DE-He213 Insulin resistance (dpeaa)DE-He213 Early origins (dpeaa)DE-He213 India (dpeaa)DE-He213 Canada (dpeaa)DE-He213 Vasudevan, Anil aut Gupta, Milan aut Morrison, Katherine aut Kurpad, Anura aut Teo, Koon K aut Srinivasan, Krishnamachari aut Enthalten in BMC public health London : BioMed Central, 2001 13(2013), 1 vom: 28. Jan. (DE-627)326643583 (DE-600)2041338-5 1471-2458 nnns volume:13 year:2013 number:1 day:28 month:01 https://dx.doi.org/10.1186/1471-2458-13-79 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 1 28 01
allfieldsGer	10.1186/1471-2458-13-79 doi (DE-627)SPR027877787 (SPR)1471-2458-13-79-e DE-627 ger DE-627 rakwb eng Anand, Sonia S verfasserin aut Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Anand et al; licensee BioMed Central Ltd. 2013 Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. Birth cohort (dpeaa)DE-He213 South Asian (dpeaa)DE-He213 Adiposity (dpeaa)DE-He213 Insulin resistance (dpeaa)DE-He213 Early origins (dpeaa)DE-He213 India (dpeaa)DE-He213 Canada (dpeaa)DE-He213 Vasudevan, Anil aut Gupta, Milan aut Morrison, Katherine aut Kurpad, Anura aut Teo, Koon K aut Srinivasan, Krishnamachari aut Enthalten in BMC public health London : BioMed Central, 2001 13(2013), 1 vom: 28. Jan. (DE-627)326643583 (DE-600)2041338-5 1471-2458 nnns volume:13 year:2013 number:1 day:28 month:01 https://dx.doi.org/10.1186/1471-2458-13-79 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 1 28 01
allfieldsSound	10.1186/1471-2458-13-79 doi (DE-627)SPR027877787 (SPR)1471-2458-13-79-e DE-627 ger DE-627 rakwb eng Anand, Sonia S verfasserin aut Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Anand et al; licensee BioMed Central Ltd. 2013 Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. Birth cohort (dpeaa)DE-He213 South Asian (dpeaa)DE-He213 Adiposity (dpeaa)DE-He213 Insulin resistance (dpeaa)DE-He213 Early origins (dpeaa)DE-He213 India (dpeaa)DE-He213 Canada (dpeaa)DE-He213 Vasudevan, Anil aut Gupta, Milan aut Morrison, Katherine aut Kurpad, Anura aut Teo, Koon K aut Srinivasan, Krishnamachari aut Enthalten in BMC public health London : BioMed Central, 2001 13(2013), 1 vom: 28. Jan. (DE-627)326643583 (DE-600)2041338-5 1471-2458 nnns volume:13 year:2013 number:1 day:28 month:01 https://dx.doi.org/10.1186/1471-2458-13-79 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 1 28 01
language	English
source	Enthalten in BMC public health 13(2013), 1 vom: 28. Jan. volume:13 year:2013 number:1 day:28 month:01
sourceStr	Enthalten in BMC public health 13(2013), 1 vom: 28. Jan. volume:13 year:2013 number:1 day:28 month:01
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Birth cohort South Asian Adiposity Insulin resistance Early origins India Canada
isfreeaccess_bool	true
container_title	BMC public health
authorswithroles_txt_mv	Anand, Sonia S @@aut@@ Vasudevan, Anil @@aut@@ Gupta, Milan @@aut@@ Morrison, Katherine @@aut@@ Kurpad, Anura @@aut@@ Teo, Koon K @@aut@@ Srinivasan, Krishnamachari @@aut@@
publishDateDaySort_date	2013-01-28T00:00:00Z
hierarchy_top_id	326643583
id	SPR027877787
language_de	englisch
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author	Anand, Sonia S
spellingShingle	Anand, Sonia S misc Birth cohort misc South Asian misc Adiposity misc Insulin resistance misc Early origins misc India misc Canada Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study
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topic_title	Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study Birth cohort (dpeaa)DE-He213 South Asian (dpeaa)DE-He213 Adiposity (dpeaa)DE-He213 Insulin resistance (dpeaa)DE-He213 Early origins (dpeaa)DE-He213 India (dpeaa)DE-He213 Canada (dpeaa)DE-He213
topic	misc Birth cohort misc South Asian misc Adiposity misc Insulin resistance misc Early origins misc India misc Canada
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title	Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study
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title_full	Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study
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title_sort	rationale and design of south asian birth cohort (start): a canada-india collaborative study
title_auth	Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study
abstract	Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. © Anand et al; licensee BioMed Central Ltd. 2013
abstractGer	Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. © Anand et al; licensee BioMed Central Ltd. 2013
abstract_unstemmed	Background People who originate from the Indian subcontinent (South Asians) suffer among the highest rates of type 2 diabetes in the world. Prior evidence suggests that metabolic risk factors develop early in life and are influenced by maternal and paternal behaviors, the intrauterine environment, and genetic factors. The South Asian Birth Cohort Study (START) will investigate the environmental and genetic basis of adiposity among 750 South Asian offspring recruited from highly divergent environments, namely, rural and urban India and urban Canada. Methods Detailed information on health behaviors including diet and physical activity, and blood samples for metabolic parameters and DNA are collected from pregnant women of South Asian ancestry who are free of significant chronic disease. They also undergo a provocative test to diagnose impaired glucose tolerance and gestational diabetes. At delivery, cord blood and newborn anthropometric indices (i.e. birth weight, length, head circumference and skin fold thickness) are collected. The mother and growing offspring are followed prospectively and information on the growth trajectory, adiposity and health behaviors will be collected annually up to age 3 years. Our aim is to recruit a minimum of 750 mother-infant pairs equally divided between three divergent environments: rural India, urban India, and Canada. Summary The START cohort will increase our understanding of the environmental and genetic determinants of adiposity and related metabolic abnormalities among South Asians living in India and Canada. © Anand et al; licensee BioMed Central Ltd. 2013
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title_short	Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study
url	https://dx.doi.org/10.1186/1471-2458-13-79
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author2	Vasudevan, Anil Gupta, Milan Morrison, Katherine Kurpad, Anura Teo, Koon K Srinivasan, Krishnamachari
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Rationale and design of South Asian Birth Cohort (START): a Canada-India collaborative study

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Vorhandene Bände

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