Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses

Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detect...
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Autor*in:	Chen, Mingshun [verfasserIn] Meng, Hecheng Zhao, Yi Chen, Fuquan Yu, Shujuan

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Sugar beet molasses Phenolic compounds Antioxidant activities Antitumor activities

Anmerkung:	© Chen et al. 2015

Übergeordnetes Werk:	Enthalten in: BMC complementary and alternative medicine - London : BioMed Central, 2001, 15(2015), 1 vom: 07. Sept.
Übergeordnetes Werk:	volume:15 ; year:2015 ; number:1 ; day:07 ; month:09

Links:	Volltext

DOI / URN:	10.1186/s12906-015-0847-5

Katalog-ID:	SPR028134214

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520			\|a Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods.
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allfields	10.1186/s12906-015-0847-5 doi (DE-627)SPR028134214 (SPR)s12906-015-0847-5-e DE-627 ger DE-627 rakwb eng Chen, Mingshun verfasserin aut Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Chen et al. 2015 Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. Sugar beet molasses (dpeaa)DE-He213 Phenolic compounds (dpeaa)DE-He213 Antioxidant activities (dpeaa)DE-He213 Antitumor activities (dpeaa)DE-He213 Meng, Hecheng aut Zhao, Yi aut Chen, Fuquan aut Yu, Shujuan aut Enthalten in BMC complementary and alternative medicine London : BioMed Central, 2001 15(2015), 1 vom: 07. Sept. (DE-627)331018713 (DE-600)2050429-9 1472-6882 nnns volume:15 year:2015 number:1 day:07 month:09 https://dx.doi.org/10.1186/s12906-015-0847-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2015 1 07 09
spelling	10.1186/s12906-015-0847-5 doi (DE-627)SPR028134214 (SPR)s12906-015-0847-5-e DE-627 ger DE-627 rakwb eng Chen, Mingshun verfasserin aut Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Chen et al. 2015 Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. Sugar beet molasses (dpeaa)DE-He213 Phenolic compounds (dpeaa)DE-He213 Antioxidant activities (dpeaa)DE-He213 Antitumor activities (dpeaa)DE-He213 Meng, Hecheng aut Zhao, Yi aut Chen, Fuquan aut Yu, Shujuan aut Enthalten in BMC complementary and alternative medicine London : BioMed Central, 2001 15(2015), 1 vom: 07. Sept. (DE-627)331018713 (DE-600)2050429-9 1472-6882 nnns volume:15 year:2015 number:1 day:07 month:09 https://dx.doi.org/10.1186/s12906-015-0847-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2015 1 07 09
allfields_unstemmed	10.1186/s12906-015-0847-5 doi (DE-627)SPR028134214 (SPR)s12906-015-0847-5-e DE-627 ger DE-627 rakwb eng Chen, Mingshun verfasserin aut Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Chen et al. 2015 Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. Sugar beet molasses (dpeaa)DE-He213 Phenolic compounds (dpeaa)DE-He213 Antioxidant activities (dpeaa)DE-He213 Antitumor activities (dpeaa)DE-He213 Meng, Hecheng aut Zhao, Yi aut Chen, Fuquan aut Yu, Shujuan aut Enthalten in BMC complementary and alternative medicine London : BioMed Central, 2001 15(2015), 1 vom: 07. Sept. (DE-627)331018713 (DE-600)2050429-9 1472-6882 nnns volume:15 year:2015 number:1 day:07 month:09 https://dx.doi.org/10.1186/s12906-015-0847-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2015 1 07 09
allfieldsGer	10.1186/s12906-015-0847-5 doi (DE-627)SPR028134214 (SPR)s12906-015-0847-5-e DE-627 ger DE-627 rakwb eng Chen, Mingshun verfasserin aut Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Chen et al. 2015 Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. Sugar beet molasses (dpeaa)DE-He213 Phenolic compounds (dpeaa)DE-He213 Antioxidant activities (dpeaa)DE-He213 Antitumor activities (dpeaa)DE-He213 Meng, Hecheng aut Zhao, Yi aut Chen, Fuquan aut Yu, Shujuan aut Enthalten in BMC complementary and alternative medicine London : BioMed Central, 2001 15(2015), 1 vom: 07. Sept. (DE-627)331018713 (DE-600)2050429-9 1472-6882 nnns volume:15 year:2015 number:1 day:07 month:09 https://dx.doi.org/10.1186/s12906-015-0847-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2015 1 07 09
allfieldsSound	10.1186/s12906-015-0847-5 doi (DE-627)SPR028134214 (SPR)s12906-015-0847-5-e DE-627 ger DE-627 rakwb eng Chen, Mingshun verfasserin aut Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Chen et al. 2015 Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. Sugar beet molasses (dpeaa)DE-He213 Phenolic compounds (dpeaa)DE-He213 Antioxidant activities (dpeaa)DE-He213 Antitumor activities (dpeaa)DE-He213 Meng, Hecheng aut Zhao, Yi aut Chen, Fuquan aut Yu, Shujuan aut Enthalten in BMC complementary and alternative medicine London : BioMed Central, 2001 15(2015), 1 vom: 07. Sept. (DE-627)331018713 (DE-600)2050429-9 1472-6882 nnns volume:15 year:2015 number:1 day:07 month:09 https://dx.doi.org/10.1186/s12906-015-0847-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2015 1 07 09
language	English
source	Enthalten in BMC complementary and alternative medicine 15(2015), 1 vom: 07. Sept. volume:15 year:2015 number:1 day:07 month:09
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topic_facet	Sugar beet molasses Phenolic compounds Antioxidant activities Antitumor activities
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Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sugar beet molasses</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Phenolic compounds</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antioxidant activities</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antitumor activities</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Meng, Hecheng</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhao, Yi</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chen, Fuquan</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yu, Shujuan</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">BMC complementary and alternative medicine</subfield><subfield code="d">London : BioMed Central, 2001</subfield><subfield code="g">15(2015), 1 vom: 07. 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author	Chen, Mingshun
spellingShingle	Chen, Mingshun misc Sugar beet molasses misc Phenolic compounds misc Antioxidant activities misc Antitumor activities Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses
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topic_title	Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses Sugar beet molasses (dpeaa)DE-He213 Phenolic compounds (dpeaa)DE-He213 Antioxidant activities (dpeaa)DE-He213 Antitumor activities (dpeaa)DE-He213
topic	misc Sugar beet molasses misc Phenolic compounds misc Antioxidant activities misc Antitumor activities
topic_unstemmed	misc Sugar beet molasses misc Phenolic compounds misc Antioxidant activities misc Antitumor activities
topic_browse	misc Sugar beet molasses misc Phenolic compounds misc Antioxidant activities misc Antitumor activities
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title	Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses
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title_full	Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses
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journal	BMC complementary and alternative medicine
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author_browse	Chen, Mingshun Meng, Hecheng Zhao, Yi Chen, Fuquan Yu, Shujuan
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author-letter	Chen, Mingshun
doi_str_mv	10.1186/s12906-015-0847-5
title_sort	antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses
title_auth	Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses
abstract	Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. © Chen et al. 2015
abstractGer	Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. © Chen et al. 2015
abstract_unstemmed	Background In the present study, the phenolic compounds were prepared using ultrasonic-aid extraction from sugar beet molasses (SBM). Methods Gallic acid (GA), cyanidin-3-O-glucoside chloride (CGC) and epicatechin (EP) were produced after column chromatography from the extraction, and further detected using NMR, QTOF-MS and ESI-MS/MS. Results The three compounds exhibited strong antioxidant activities including DPPH radical scavenging activities, ABTS radical scavenging activities and ORAC values. GA showed the strongest antioxidant activity. Antitumor activities significantly increased in a dose-dependent manner. In particular, the CGC had growth inhibitory activities of 94.86, 87.27 and 67.13 % against the human colon (CACO-2), hepatocellular (HepG2) and breast (MCF-7) carcinoma cell lines, respectively, at the highest concentration of 400 μg/mL of the extracts. These results suggest that the three compounds are key chemical compositions valuable for preparing functional foods in the food industry. Conclusions The results suggested that SBM is a natural source of antioxidant and antitumor agents for preparing functional foods. © Chen et al. 2015
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title_short	Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses
url	https://dx.doi.org/10.1186/s12906-015-0847-5
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author2	Meng, Hecheng Zhao, Yi Chen, Fuquan Yu, Shujuan
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up_date	2024-07-03T17:30:29.821Z
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Antioxidant and in vitro anticancer activities of phenolics isolated from sugar beet molasses

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