Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment

Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Maltezou, Helena C [verfasserIn] Papa, Anna

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2011

Schlagwörter:	Case Fatality Rate Seroprevalence Rate Wide Geographic Range Balkan Country Standardize Case Definition

Anmerkung:	© Maltezou and Papa; licensee BioMed Central Ltd. 2011

Übergeordnetes Werk:	Enthalten in: BMC medicine - London : BioMed Central, 2003, 9(2011), 1 vom: 08. Dez.
Übergeordnetes Werk:	volume:9 ; year:2011 ; number:1 ; day:08 ; month:12

Links:	Volltext

DOI / URN:	10.1186/1741-7015-9-131

Katalog-ID:	SPR028346777

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allfields	10.1186/1741-7015-9-131 doi (DE-627)SPR028346777 (SPR)1741-7015-9-131-e DE-627 ger DE-627 rakwb eng Maltezou, Helena C verfasserin aut Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maltezou and Papa; licensee BioMed Central Ltd. 2011 Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. Case Fatality Rate (dpeaa)DE-He213 Seroprevalence Rate (dpeaa)DE-He213 Wide Geographic Range (dpeaa)DE-He213 Balkan Country (dpeaa)DE-He213 Standardize Case Definition (dpeaa)DE-He213 Papa, Anna aut Enthalten in BMC medicine London : BioMed Central, 2003 9(2011), 1 vom: 08. Dez. (DE-627)377271225 (DE-600)2131669-7 1741-7015 nnns volume:9 year:2011 number:1 day:08 month:12 https://dx.doi.org/10.1186/1741-7015-9-131 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2011 1 08 12
spelling	10.1186/1741-7015-9-131 doi (DE-627)SPR028346777 (SPR)1741-7015-9-131-e DE-627 ger DE-627 rakwb eng Maltezou, Helena C verfasserin aut Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maltezou and Papa; licensee BioMed Central Ltd. 2011 Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. Case Fatality Rate (dpeaa)DE-He213 Seroprevalence Rate (dpeaa)DE-He213 Wide Geographic Range (dpeaa)DE-He213 Balkan Country (dpeaa)DE-He213 Standardize Case Definition (dpeaa)DE-He213 Papa, Anna aut Enthalten in BMC medicine London : BioMed Central, 2003 9(2011), 1 vom: 08. Dez. (DE-627)377271225 (DE-600)2131669-7 1741-7015 nnns volume:9 year:2011 number:1 day:08 month:12 https://dx.doi.org/10.1186/1741-7015-9-131 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2011 1 08 12
allfields_unstemmed	10.1186/1741-7015-9-131 doi (DE-627)SPR028346777 (SPR)1741-7015-9-131-e DE-627 ger DE-627 rakwb eng Maltezou, Helena C verfasserin aut Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maltezou and Papa; licensee BioMed Central Ltd. 2011 Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. Case Fatality Rate (dpeaa)DE-He213 Seroprevalence Rate (dpeaa)DE-He213 Wide Geographic Range (dpeaa)DE-He213 Balkan Country (dpeaa)DE-He213 Standardize Case Definition (dpeaa)DE-He213 Papa, Anna aut Enthalten in BMC medicine London : BioMed Central, 2003 9(2011), 1 vom: 08. Dez. (DE-627)377271225 (DE-600)2131669-7 1741-7015 nnns volume:9 year:2011 number:1 day:08 month:12 https://dx.doi.org/10.1186/1741-7015-9-131 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2011 1 08 12
allfieldsGer	10.1186/1741-7015-9-131 doi (DE-627)SPR028346777 (SPR)1741-7015-9-131-e DE-627 ger DE-627 rakwb eng Maltezou, Helena C verfasserin aut Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maltezou and Papa; licensee BioMed Central Ltd. 2011 Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. Case Fatality Rate (dpeaa)DE-He213 Seroprevalence Rate (dpeaa)DE-He213 Wide Geographic Range (dpeaa)DE-He213 Balkan Country (dpeaa)DE-He213 Standardize Case Definition (dpeaa)DE-He213 Papa, Anna aut Enthalten in BMC medicine London : BioMed Central, 2003 9(2011), 1 vom: 08. Dez. (DE-627)377271225 (DE-600)2131669-7 1741-7015 nnns volume:9 year:2011 number:1 day:08 month:12 https://dx.doi.org/10.1186/1741-7015-9-131 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2011 1 08 12
allfieldsSound	10.1186/1741-7015-9-131 doi (DE-627)SPR028346777 (SPR)1741-7015-9-131-e DE-627 ger DE-627 rakwb eng Maltezou, Helena C verfasserin aut Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maltezou and Papa; licensee BioMed Central Ltd. 2011 Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. Case Fatality Rate (dpeaa)DE-He213 Seroprevalence Rate (dpeaa)DE-He213 Wide Geographic Range (dpeaa)DE-He213 Balkan Country (dpeaa)DE-He213 Standardize Case Definition (dpeaa)DE-He213 Papa, Anna aut Enthalten in BMC medicine London : BioMed Central, 2003 9(2011), 1 vom: 08. Dez. (DE-627)377271225 (DE-600)2131669-7 1741-7015 nnns volume:9 year:2011 number:1 day:08 month:12 https://dx.doi.org/10.1186/1741-7015-9-131 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2011 1 08 12
language	English
source	Enthalten in BMC medicine 9(2011), 1 vom: 08. Dez. volume:9 year:2011 number:1 day:08 month:12
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topic_facet	Case Fatality Rate Seroprevalence Rate Wide Geographic Range Balkan Country Standardize Case Definition
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container_title	BMC medicine
authorswithroles_txt_mv	Maltezou, Helena C @@aut@@ Papa, Anna @@aut@@
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topic_title	Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment Case Fatality Rate (dpeaa)DE-He213 Seroprevalence Rate (dpeaa)DE-He213 Wide Geographic Range (dpeaa)DE-He213 Balkan Country (dpeaa)DE-He213 Standardize Case Definition (dpeaa)DE-He213
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title	Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment
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title_sort	crimean-congo hemorrhagic fever: epidemiological trends and controversies in treatment
title_auth	Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment
abstract	Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. © Maltezou and Papa; licensee BioMed Central Ltd. 2011
abstractGer	Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. © Maltezou and Papa; licensee BioMed Central Ltd. 2011
abstract_unstemmed	Abstract Crimean-Congo hemorrhagic fever (CCHF) virus has the widest geographic range of all tick-borne viruses and is endemic in more than 30 countries in Eurasia and Africa. Over the past decade, new foci have emerged or re-emerged in the Balkans and neighboring areas. Here we discuss the factors influencing CCHF incidence and focus on the main issue of the use of ribavirin for treating this infection. Given the dynamics of CCHF emergence in the past decade, development of new anti-viral drugs and a vaccine is urgently needed to treat and prevent this acute, life-threatening disease. © Maltezou and Papa; licensee BioMed Central Ltd. 2011
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title_short	Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment
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Crimean-Congo hemorrhagic fever: epidemiological trends and controversies in treatment

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