The Roche Cancer Genome Database 2.0

Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed...
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Autor*in:	Küntzer, Jan [verfasserIn] Maisel, Daniela Lenhof, Hans-Peter Klostermann, Stefan Burtscher, Helmut

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2011

Schlagwörter:	Cancer Genome Search Interface Filter Criterion Cancer Genome Data Cancer Genome Atlas Project

Anmerkung:	© Küntzer et al; licensee BioMed Central Ltd. 2011

Übergeordnetes Werk:	Enthalten in: BMC medical genomics - London : BioMed Central, 2008, 4(2011), 1 vom: 17. Mai
Übergeordnetes Werk:	volume:4 ; year:2011 ; number:1 ; day:17 ; month:05

Links:	Volltext

DOI / URN:	10.1186/1755-8794-4-43

Katalog-ID:	SPR02846690X

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520			\|a Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/.
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allfields	10.1186/1755-8794-4-43 doi (DE-627)SPR02846690X (SPR)1755-8794-4-43-e DE-627 ger DE-627 rakwb eng Küntzer, Jan verfasserin aut The Roche Cancer Genome Database 2.0 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Küntzer et al; licensee BioMed Central Ltd. 2011 Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. Cancer Genome (dpeaa)DE-He213 Search Interface (dpeaa)DE-He213 Filter Criterion (dpeaa)DE-He213 Cancer Genome Data (dpeaa)DE-He213 Cancer Genome Atlas Project (dpeaa)DE-He213 Maisel, Daniela aut Lenhof, Hans-Peter aut Klostermann, Stefan aut Burtscher, Helmut aut Enthalten in BMC medical genomics London : BioMed Central, 2008 4(2011), 1 vom: 17. Mai (DE-627)559080824 (DE-600)2411865-5 1755-8794 nnns volume:4 year:2011 number:1 day:17 month:05 https://dx.doi.org/10.1186/1755-8794-4-43 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2011 1 17 05
spelling	10.1186/1755-8794-4-43 doi (DE-627)SPR02846690X (SPR)1755-8794-4-43-e DE-627 ger DE-627 rakwb eng Küntzer, Jan verfasserin aut The Roche Cancer Genome Database 2.0 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Küntzer et al; licensee BioMed Central Ltd. 2011 Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. Cancer Genome (dpeaa)DE-He213 Search Interface (dpeaa)DE-He213 Filter Criterion (dpeaa)DE-He213 Cancer Genome Data (dpeaa)DE-He213 Cancer Genome Atlas Project (dpeaa)DE-He213 Maisel, Daniela aut Lenhof, Hans-Peter aut Klostermann, Stefan aut Burtscher, Helmut aut Enthalten in BMC medical genomics London : BioMed Central, 2008 4(2011), 1 vom: 17. Mai (DE-627)559080824 (DE-600)2411865-5 1755-8794 nnns volume:4 year:2011 number:1 day:17 month:05 https://dx.doi.org/10.1186/1755-8794-4-43 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2011 1 17 05
allfields_unstemmed	10.1186/1755-8794-4-43 doi (DE-627)SPR02846690X (SPR)1755-8794-4-43-e DE-627 ger DE-627 rakwb eng Küntzer, Jan verfasserin aut The Roche Cancer Genome Database 2.0 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Küntzer et al; licensee BioMed Central Ltd. 2011 Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. Cancer Genome (dpeaa)DE-He213 Search Interface (dpeaa)DE-He213 Filter Criterion (dpeaa)DE-He213 Cancer Genome Data (dpeaa)DE-He213 Cancer Genome Atlas Project (dpeaa)DE-He213 Maisel, Daniela aut Lenhof, Hans-Peter aut Klostermann, Stefan aut Burtscher, Helmut aut Enthalten in BMC medical genomics London : BioMed Central, 2008 4(2011), 1 vom: 17. Mai (DE-627)559080824 (DE-600)2411865-5 1755-8794 nnns volume:4 year:2011 number:1 day:17 month:05 https://dx.doi.org/10.1186/1755-8794-4-43 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2011 1 17 05
allfieldsGer	10.1186/1755-8794-4-43 doi (DE-627)SPR02846690X (SPR)1755-8794-4-43-e DE-627 ger DE-627 rakwb eng Küntzer, Jan verfasserin aut The Roche Cancer Genome Database 2.0 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Küntzer et al; licensee BioMed Central Ltd. 2011 Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. Cancer Genome (dpeaa)DE-He213 Search Interface (dpeaa)DE-He213 Filter Criterion (dpeaa)DE-He213 Cancer Genome Data (dpeaa)DE-He213 Cancer Genome Atlas Project (dpeaa)DE-He213 Maisel, Daniela aut Lenhof, Hans-Peter aut Klostermann, Stefan aut Burtscher, Helmut aut Enthalten in BMC medical genomics London : BioMed Central, 2008 4(2011), 1 vom: 17. Mai (DE-627)559080824 (DE-600)2411865-5 1755-8794 nnns volume:4 year:2011 number:1 day:17 month:05 https://dx.doi.org/10.1186/1755-8794-4-43 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2011 1 17 05
allfieldsSound	10.1186/1755-8794-4-43 doi (DE-627)SPR02846690X (SPR)1755-8794-4-43-e DE-627 ger DE-627 rakwb eng Küntzer, Jan verfasserin aut The Roche Cancer Genome Database 2.0 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Küntzer et al; licensee BioMed Central Ltd. 2011 Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. Cancer Genome (dpeaa)DE-He213 Search Interface (dpeaa)DE-He213 Filter Criterion (dpeaa)DE-He213 Cancer Genome Data (dpeaa)DE-He213 Cancer Genome Atlas Project (dpeaa)DE-He213 Maisel, Daniela aut Lenhof, Hans-Peter aut Klostermann, Stefan aut Burtscher, Helmut aut Enthalten in BMC medical genomics London : BioMed Central, 2008 4(2011), 1 vom: 17. Mai (DE-627)559080824 (DE-600)2411865-5 1755-8794 nnns volume:4 year:2011 number:1 day:17 month:05 https://dx.doi.org/10.1186/1755-8794-4-43 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2011 1 17 05
language	English
source	Enthalten in BMC medical genomics 4(2011), 1 vom: 17. Mai volume:4 year:2011 number:1 day:17 month:05
sourceStr	Enthalten in BMC medical genomics 4(2011), 1 vom: 17. Mai volume:4 year:2011 number:1 day:17 month:05
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Cancer Genome Search Interface Filter Criterion Cancer Genome Data Cancer Genome Atlas Project
isfreeaccess_bool	true
container_title	BMC medical genomics
authorswithroles_txt_mv	Küntzer, Jan @@aut@@ Maisel, Daniela @@aut@@ Lenhof, Hans-Peter @@aut@@ Klostermann, Stefan @@aut@@ Burtscher, Helmut @@aut@@
publishDateDaySort_date	2011-05-17T00:00:00Z
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spellingShingle	Küntzer, Jan misc Cancer Genome misc Search Interface misc Filter Criterion misc Cancer Genome Data misc Cancer Genome Atlas Project The Roche Cancer Genome Database 2.0
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topic_title	The Roche Cancer Genome Database 2.0 Cancer Genome (dpeaa)DE-He213 Search Interface (dpeaa)DE-He213 Filter Criterion (dpeaa)DE-He213 Cancer Genome Data (dpeaa)DE-He213 Cancer Genome Atlas Project (dpeaa)DE-He213
topic	misc Cancer Genome misc Search Interface misc Filter Criterion misc Cancer Genome Data misc Cancer Genome Atlas Project
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title	The Roche Cancer Genome Database 2.0
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title_full	The Roche Cancer Genome Database 2.0
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abstract	Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. © Küntzer et al; licensee BioMed Central Ltd. 2011
abstractGer	Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. © Küntzer et al; licensee BioMed Central Ltd. 2011
abstract_unstemmed	Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumor types or predict outcome. Description We have constructed an integrated biological information system termed the Roche Cancer Genome Database (RCGDB) combining different human mutation databases already publicly available. This data is further extended by hand-curated information from publications. The current version of the RCGDB provides a user-friendly graphical interface that gives access to the data in different ways: (1) Single interactive search by genes, samples, cell lines, diseases, as well as pathways, (2) batch searches for genes and cell lines, (3) customized searches for regularly occurring requests, and (4) an advanced query interface enabling the user to query for samples and mutations by various filter criteria. Conclusion The interfaces of the presented database enable the user to search and view mutations in an intuitive and straight-forward manner. The database is freely accessible at http://rcgdb.bioinf.uni-sb.de/MutomeWeb/. © Küntzer et al; licensee BioMed Central Ltd. 2011
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title_short	The Roche Cancer Genome Database 2.0
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author2	Maisel, Daniela Lenhof, Hans-Peter Klostermann, Stefan Burtscher, Helmut
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score	7.399932

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The Roche Cancer Genome Database 2.0

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