Analysis of comorbid factors that increase the COPD assessment test scores

Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may co...
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Autor*in:	Miyazaki, Masaki [verfasserIn] Nakamura, Hidetoshi Chubachi, Shotaro Sasaki, Mamoru Haraguchi, Mizuha Yoshida, Shuichi Tsuduki, Keishi Shirahata, Toru Takahashi, Saeko Minematsu, Naoto Koh, Hidefumi Nakamura, Morio Sakamaki, Fumio Terashima, Takeshi Sayama, Koichi Jones, Paul W Asano, Koichiro Betsuyaku, Tomoko

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Chronic obstructive pulmonary disease Health status Depression Gastro-esophageal reflux Comorbidity Osteoporosis

Anmerkung:	© Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (

Übergeordnetes Werk:	Enthalten in: Respiratory research - London : BioMed Central, 2001, 15(2014), 1 vom: 06. Feb.
Übergeordnetes Werk:	volume:15 ; year:2014 ; number:1 ; day:06 ; month:02

Links:	Volltext

DOI / URN:	10.1186/1465-9921-15-13

Katalog-ID:	SPR028517407

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520			\|a Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470).
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allfields	10.1186/1465-9921-15-13 doi (DE-627)SPR028517407 (SPR)1465-9921-15-13-e DE-627 ger DE-627 rakwb eng Miyazaki, Masaki verfasserin aut Analysis of comorbid factors that increase the COPD assessment test scores 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). Chronic obstructive pulmonary disease (dpeaa)DE-He213 Health status (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Gastro-esophageal reflux (dpeaa)DE-He213 Comorbidity (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Nakamura, Hidetoshi aut Chubachi, Shotaro aut Sasaki, Mamoru aut Haraguchi, Mizuha aut Yoshida, Shuichi aut Tsuduki, Keishi aut Shirahata, Toru aut Takahashi, Saeko aut Minematsu, Naoto aut Koh, Hidefumi aut Nakamura, Morio aut Sakamaki, Fumio aut Terashima, Takeshi aut Sayama, Koichi aut Jones, Paul W aut Asano, Koichiro aut Betsuyaku, Tomoko aut Enthalten in Respiratory research London : BioMed Central, 2001 15(2014), 1 vom: 06. Feb. (DE-627)326646485 (DE-600)2041675-1 1465-993X nnns volume:15 year:2014 number:1 day:06 month:02 https://dx.doi.org/10.1186/1465-9921-15-13 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2014 1 06 02
spelling	10.1186/1465-9921-15-13 doi (DE-627)SPR028517407 (SPR)1465-9921-15-13-e DE-627 ger DE-627 rakwb eng Miyazaki, Masaki verfasserin aut Analysis of comorbid factors that increase the COPD assessment test scores 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). Chronic obstructive pulmonary disease (dpeaa)DE-He213 Health status (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Gastro-esophageal reflux (dpeaa)DE-He213 Comorbidity (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Nakamura, Hidetoshi aut Chubachi, Shotaro aut Sasaki, Mamoru aut Haraguchi, Mizuha aut Yoshida, Shuichi aut Tsuduki, Keishi aut Shirahata, Toru aut Takahashi, Saeko aut Minematsu, Naoto aut Koh, Hidefumi aut Nakamura, Morio aut Sakamaki, Fumio aut Terashima, Takeshi aut Sayama, Koichi aut Jones, Paul W aut Asano, Koichiro aut Betsuyaku, Tomoko aut Enthalten in Respiratory research London : BioMed Central, 2001 15(2014), 1 vom: 06. Feb. (DE-627)326646485 (DE-600)2041675-1 1465-993X nnns volume:15 year:2014 number:1 day:06 month:02 https://dx.doi.org/10.1186/1465-9921-15-13 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2014 1 06 02
allfields_unstemmed	10.1186/1465-9921-15-13 doi (DE-627)SPR028517407 (SPR)1465-9921-15-13-e DE-627 ger DE-627 rakwb eng Miyazaki, Masaki verfasserin aut Analysis of comorbid factors that increase the COPD assessment test scores 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). Chronic obstructive pulmonary disease (dpeaa)DE-He213 Health status (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Gastro-esophageal reflux (dpeaa)DE-He213 Comorbidity (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Nakamura, Hidetoshi aut Chubachi, Shotaro aut Sasaki, Mamoru aut Haraguchi, Mizuha aut Yoshida, Shuichi aut Tsuduki, Keishi aut Shirahata, Toru aut Takahashi, Saeko aut Minematsu, Naoto aut Koh, Hidefumi aut Nakamura, Morio aut Sakamaki, Fumio aut Terashima, Takeshi aut Sayama, Koichi aut Jones, Paul W aut Asano, Koichiro aut Betsuyaku, Tomoko aut Enthalten in Respiratory research London : BioMed Central, 2001 15(2014), 1 vom: 06. Feb. (DE-627)326646485 (DE-600)2041675-1 1465-993X nnns volume:15 year:2014 number:1 day:06 month:02 https://dx.doi.org/10.1186/1465-9921-15-13 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2014 1 06 02
allfieldsGer	10.1186/1465-9921-15-13 doi (DE-627)SPR028517407 (SPR)1465-9921-15-13-e DE-627 ger DE-627 rakwb eng Miyazaki, Masaki verfasserin aut Analysis of comorbid factors that increase the COPD assessment test scores 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). Chronic obstructive pulmonary disease (dpeaa)DE-He213 Health status (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Gastro-esophageal reflux (dpeaa)DE-He213 Comorbidity (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Nakamura, Hidetoshi aut Chubachi, Shotaro aut Sasaki, Mamoru aut Haraguchi, Mizuha aut Yoshida, Shuichi aut Tsuduki, Keishi aut Shirahata, Toru aut Takahashi, Saeko aut Minematsu, Naoto aut Koh, Hidefumi aut Nakamura, Morio aut Sakamaki, Fumio aut Terashima, Takeshi aut Sayama, Koichi aut Jones, Paul W aut Asano, Koichiro aut Betsuyaku, Tomoko aut Enthalten in Respiratory research London : BioMed Central, 2001 15(2014), 1 vom: 06. Feb. (DE-627)326646485 (DE-600)2041675-1 1465-993X nnns volume:15 year:2014 number:1 day:06 month:02 https://dx.doi.org/10.1186/1465-9921-15-13 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2014 1 06 02
allfieldsSound	10.1186/1465-9921-15-13 doi (DE-627)SPR028517407 (SPR)1465-9921-15-13-e DE-627 ger DE-627 rakwb eng Miyazaki, Masaki verfasserin aut Analysis of comorbid factors that increase the COPD assessment test scores 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). Chronic obstructive pulmonary disease (dpeaa)DE-He213 Health status (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Gastro-esophageal reflux (dpeaa)DE-He213 Comorbidity (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Nakamura, Hidetoshi aut Chubachi, Shotaro aut Sasaki, Mamoru aut Haraguchi, Mizuha aut Yoshida, Shuichi aut Tsuduki, Keishi aut Shirahata, Toru aut Takahashi, Saeko aut Minematsu, Naoto aut Koh, Hidefumi aut Nakamura, Morio aut Sakamaki, Fumio aut Terashima, Takeshi aut Sayama, Koichi aut Jones, Paul W aut Asano, Koichiro aut Betsuyaku, Tomoko aut Enthalten in Respiratory research London : BioMed Central, 2001 15(2014), 1 vom: 06. Feb. (DE-627)326646485 (DE-600)2041675-1 1465-993X nnns volume:15 year:2014 number:1 day:06 month:02 https://dx.doi.org/10.1186/1465-9921-15-13 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2014 1 06 02
language	English
source	Enthalten in Respiratory research 15(2014), 1 vom: 06. Feb. volume:15 year:2014 number:1 day:06 month:02
sourceStr	Enthalten in Respiratory research 15(2014), 1 vom: 06. Feb. volume:15 year:2014 number:1 day:06 month:02
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Chronic obstructive pulmonary disease Health status Depression Gastro-esophageal reflux Comorbidity Osteoporosis
isfreeaccess_bool	true
container_title	Respiratory research
authorswithroles_txt_mv	Miyazaki, Masaki @@aut@@ Nakamura, Hidetoshi @@aut@@ Chubachi, Shotaro @@aut@@ Sasaki, Mamoru @@aut@@ Haraguchi, Mizuha @@aut@@ Yoshida, Shuichi @@aut@@ Tsuduki, Keishi @@aut@@ Shirahata, Toru @@aut@@ Takahashi, Saeko @@aut@@ Minematsu, Naoto @@aut@@ Koh, Hidefumi @@aut@@ Nakamura, Morio @@aut@@ Sakamaki, Fumio @@aut@@ Terashima, Takeshi @@aut@@ Sayama, Koichi @@aut@@ Jones, Paul W @@aut@@ Asano, Koichiro @@aut@@ Betsuyaku, Tomoko @@aut@@
publishDateDaySort_date	2014-02-06T00:00:00Z
hierarchy_top_id	326646485
id	SPR028517407
language_de	englisch
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author	Miyazaki, Masaki
spellingShingle	Miyazaki, Masaki misc Chronic obstructive pulmonary disease misc Health status misc Depression misc Gastro-esophageal reflux misc Comorbidity misc Osteoporosis Analysis of comorbid factors that increase the COPD assessment test scores
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topic_title	Analysis of comorbid factors that increase the COPD assessment test scores Chronic obstructive pulmonary disease (dpeaa)DE-He213 Health status (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Gastro-esophageal reflux (dpeaa)DE-He213 Comorbidity (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213
topic	misc Chronic obstructive pulmonary disease misc Health status misc Depression misc Gastro-esophageal reflux misc Comorbidity misc Osteoporosis
topic_unstemmed	misc Chronic obstructive pulmonary disease misc Health status misc Depression misc Gastro-esophageal reflux misc Comorbidity misc Osteoporosis
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title	Analysis of comorbid factors that increase the COPD assessment test scores
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title_full	Analysis of comorbid factors that increase the COPD assessment test scores
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author_browse	Miyazaki, Masaki Nakamura, Hidetoshi Chubachi, Shotaro Sasaki, Mamoru Haraguchi, Mizuha Yoshida, Shuichi Tsuduki, Keishi Shirahata, Toru Takahashi, Saeko Minematsu, Naoto Koh, Hidefumi Nakamura, Morio Sakamaki, Fumio Terashima, Takeshi Sayama, Koichi Jones, Paul W Asano, Koichiro Betsuyaku, Tomoko
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title_sort	analysis of comorbid factors that increase the copd assessment test scores
title_auth	Analysis of comorbid factors that increase the COPD assessment test scores
abstract	Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
abstractGer	Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
abstract_unstemmed	Background The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores. Methods An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients’ reports, physicians’ records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed. Results The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients. Conclusions Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration Clinical trial registered with UMIN (UMIN000003470). © Miyazaki et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
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title_short	Analysis of comorbid factors that increase the COPD assessment test scores
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author2	Nakamura, Hidetoshi Chubachi, Shotaro Sasaki, Mamoru Haraguchi, Mizuha Yoshida, Shuichi Tsuduki, Keishi Shirahata, Toru Takahashi, Saeko Minematsu, Naoto Koh, Hidefumi Nakamura, Morio Sakamaki, Fumio Terashima, Takeshi Sayama, Koichi Jones, Paul W Asano, Koichiro Betsuyaku, Tomoko
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Analysis of comorbid factors that increase the COPD assessment test scores

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