Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)

Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the...
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Autor*in:	Ślebioda, Zuzanna [verfasserIn] Krawiecka, Ewa Szponar, Elżbieta Dorocka-Bobkowska, Barbara

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	Recurrent aphthous stomatitis Zinc Oral mucosa Oral diseases

Anmerkung:	© The Author(s). 2017

Übergeordnetes Werk:	Enthalten in: BMC oral health - London : BioMed Central, 2001, 17(2017), 1 vom: 20. Dez.
Übergeordnetes Werk:	volume:17 ; year:2017 ; number:1 ; day:20 ; month:12

Links:	Volltext

DOI / URN:	10.1186/s12903-017-0450-x

Katalog-ID:	SPR028745221

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520			\|a Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS.
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allfields	10.1186/s12903-017-0450-x doi (DE-627)SPR028745221 (SPR)s12903-017-0450-x-e DE-627 ger DE-627 rakwb eng Ślebioda, Zuzanna verfasserin aut Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS) 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2017 Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. Recurrent aphthous stomatitis (dpeaa)DE-He213 Zinc (dpeaa)DE-He213 Oral mucosa (dpeaa)DE-He213 Oral diseases (dpeaa)DE-He213 Krawiecka, Ewa aut Szponar, Elżbieta aut Dorocka-Bobkowska, Barbara aut Enthalten in BMC oral health London : BioMed Central, 2001 17(2017), 1 vom: 20. Dez. (DE-627)355500108 (DE-600)2091511-1 1472-6831 nnns volume:17 year:2017 number:1 day:20 month:12 https://dx.doi.org/10.1186/s12903-017-0450-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2017 1 20 12
spelling	10.1186/s12903-017-0450-x doi (DE-627)SPR028745221 (SPR)s12903-017-0450-x-e DE-627 ger DE-627 rakwb eng Ślebioda, Zuzanna verfasserin aut Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS) 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2017 Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. Recurrent aphthous stomatitis (dpeaa)DE-He213 Zinc (dpeaa)DE-He213 Oral mucosa (dpeaa)DE-He213 Oral diseases (dpeaa)DE-He213 Krawiecka, Ewa aut Szponar, Elżbieta aut Dorocka-Bobkowska, Barbara aut Enthalten in BMC oral health London : BioMed Central, 2001 17(2017), 1 vom: 20. Dez. (DE-627)355500108 (DE-600)2091511-1 1472-6831 nnns volume:17 year:2017 number:1 day:20 month:12 https://dx.doi.org/10.1186/s12903-017-0450-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2017 1 20 12
allfields_unstemmed	10.1186/s12903-017-0450-x doi (DE-627)SPR028745221 (SPR)s12903-017-0450-x-e DE-627 ger DE-627 rakwb eng Ślebioda, Zuzanna verfasserin aut Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS) 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2017 Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. Recurrent aphthous stomatitis (dpeaa)DE-He213 Zinc (dpeaa)DE-He213 Oral mucosa (dpeaa)DE-He213 Oral diseases (dpeaa)DE-He213 Krawiecka, Ewa aut Szponar, Elżbieta aut Dorocka-Bobkowska, Barbara aut Enthalten in BMC oral health London : BioMed Central, 2001 17(2017), 1 vom: 20. Dez. (DE-627)355500108 (DE-600)2091511-1 1472-6831 nnns volume:17 year:2017 number:1 day:20 month:12 https://dx.doi.org/10.1186/s12903-017-0450-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2017 1 20 12
allfieldsGer	10.1186/s12903-017-0450-x doi (DE-627)SPR028745221 (SPR)s12903-017-0450-x-e DE-627 ger DE-627 rakwb eng Ślebioda, Zuzanna verfasserin aut Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS) 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2017 Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. Recurrent aphthous stomatitis (dpeaa)DE-He213 Zinc (dpeaa)DE-He213 Oral mucosa (dpeaa)DE-He213 Oral diseases (dpeaa)DE-He213 Krawiecka, Ewa aut Szponar, Elżbieta aut Dorocka-Bobkowska, Barbara aut Enthalten in BMC oral health London : BioMed Central, 2001 17(2017), 1 vom: 20. Dez. (DE-627)355500108 (DE-600)2091511-1 1472-6831 nnns volume:17 year:2017 number:1 day:20 month:12 https://dx.doi.org/10.1186/s12903-017-0450-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2017 1 20 12
allfieldsSound	10.1186/s12903-017-0450-x doi (DE-627)SPR028745221 (SPR)s12903-017-0450-x-e DE-627 ger DE-627 rakwb eng Ślebioda, Zuzanna verfasserin aut Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS) 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2017 Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. Recurrent aphthous stomatitis (dpeaa)DE-He213 Zinc (dpeaa)DE-He213 Oral mucosa (dpeaa)DE-He213 Oral diseases (dpeaa)DE-He213 Krawiecka, Ewa aut Szponar, Elżbieta aut Dorocka-Bobkowska, Barbara aut Enthalten in BMC oral health London : BioMed Central, 2001 17(2017), 1 vom: 20. Dez. (DE-627)355500108 (DE-600)2091511-1 1472-6831 nnns volume:17 year:2017 number:1 day:20 month:12 https://dx.doi.org/10.1186/s12903-017-0450-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2017 1 20 12
language	English
source	Enthalten in BMC oral health 17(2017), 1 vom: 20. Dez. volume:17 year:2017 number:1 day:20 month:12
sourceStr	Enthalten in BMC oral health 17(2017), 1 vom: 20. Dez. volume:17 year:2017 number:1 day:20 month:12
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Recurrent aphthous stomatitis Zinc Oral mucosa Oral diseases
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container_title	BMC oral health
authorswithroles_txt_mv	Ślebioda, Zuzanna @@aut@@ Krawiecka, Ewa @@aut@@ Szponar, Elżbieta @@aut@@ Dorocka-Bobkowska, Barbara @@aut@@
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The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. 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author	Ślebioda, Zuzanna
spellingShingle	Ślebioda, Zuzanna misc Recurrent aphthous stomatitis misc Zinc misc Oral mucosa misc Oral diseases Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)
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topic_title	Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS) Recurrent aphthous stomatitis (dpeaa)DE-He213 Zinc (dpeaa)DE-He213 Oral mucosa (dpeaa)DE-He213 Oral diseases (dpeaa)DE-He213
topic	misc Recurrent aphthous stomatitis misc Zinc misc Oral mucosa misc Oral diseases
topic_unstemmed	misc Recurrent aphthous stomatitis misc Zinc misc Oral mucosa misc Oral diseases
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title	Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)
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title_full	Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)
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author_browse	Ślebioda, Zuzanna Krawiecka, Ewa Szponar, Elżbieta Dorocka-Bobkowska, Barbara
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doi_str_mv	10.1186/s12903-017-0450-x
title_sort	evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (ras)
title_auth	Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)
abstract	Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. © The Author(s). 2017
abstractGer	Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. © The Author(s). 2017
abstract_unstemmed	Background Recurrent aphthous stomatitis (RAS) is an ulcerative disease of the oral mucosa without a clearly defined etiology. The aim of the study was to evaluate the serum zinc levels in patients with RAS in comparison to healthy controls and to validate the association between zinc levels and the course of RAS. Methods Seventy-five patients with RAS and 72 controls underwent full dental examination. Serum zinc levels were determined by flame atomic absorption spectroscopy (F AAS). The results were statistically analyzed with Kruskal-Wallis, Mann-Whitney, chi-square tests and the test of difference between the two rates of structure with p < 0.05 as a significance level (Statistica 10, StatSoft®). Results No statistically significant differences were detected in serum zinc levels between RAS patients and healthy controls. The mean serum zinc concentration was found to be 84.2 μg/dL in RAS group and 83.9 μd/dL in controls, within the accepted norms. Zinc deficiency was observed in 10.7% patients from the RAS group and in 6.9% controls. No significant differences in serum zinc levels were found between patients when the course of the disease was considered. Conclusions Serum zinc concentrations did not differ significantly in RAS patients and in healthy controls and it did not influence the course of the disease. Therefore, zinc does not appear to be an important modifying factor in the development of RAS. © The Author(s). 2017
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title_short	Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)
url	https://dx.doi.org/10.1186/s12903-017-0450-x
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author2	Krawiecka, Ewa Szponar, Elżbieta Dorocka-Bobkowska, Barbara
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Evaluation of serum zinc levels in patients with recurrent aphthous stomatitis (RAS)

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