Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL
Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a...
Ausführliche Beschreibung
Autor*in: |
Gentile, Stéphanie [verfasserIn] |
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E-Artikel |
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Englisch |
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2008 |
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Anmerkung: |
© Gentile et al; licensee BioMed Central Ltd. 2008 |
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Übergeordnetes Werk: |
Enthalten in: Health and quality of life outcomes - London : BioMed Central, 2003, 6(2008), 1 vom: 13. Okt. |
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Übergeordnetes Werk: |
volume:6 ; year:2008 ; number:1 ; day:13 ; month:10 |
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DOI / URN: |
10.1186/1477-7525-6-78 |
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Katalog-ID: |
SPR028783417 |
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520 | |a Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. | ||
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650 | 4 | |a Cognitive Debriefing |7 (dpeaa)DE-He213 | |
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700 | 1 | |a Jouve, Elisabeth |4 aut | |
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700 | 1 | |a Sambuc, Roland |4 aut | |
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10.1186/1477-7525-6-78 doi (DE-627)SPR028783417 (SPR)1477-7525-6-78-e DE-627 ger DE-627 rakwb eng Gentile, Stéphanie verfasserin aut Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Gentile et al; licensee BioMed Central Ltd. 2008 Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. Stressful Life Event (dpeaa)DE-He213 Renal Transplant Recipient (dpeaa)DE-He213 General Health Perception (dpeaa)DE-He213 Cognitive Debriefing (dpeaa)DE-He213 Item Level Analysis (dpeaa)DE-He213 Jouve, Elisabeth aut Dussol, Bertrand aut Moal, Valerie aut Berland, Yvon aut Sambuc, Roland aut Enthalten in Health and quality of life outcomes London : BioMed Central, 2003 6(2008), 1 vom: 13. Okt. (DE-627)360059651 (DE-600)2098765-1 1477-7525 nnns volume:6 year:2008 number:1 day:13 month:10 https://dx.doi.org/10.1186/1477-7525-6-78 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_375 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2008 1 13 10 |
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10.1186/1477-7525-6-78 doi (DE-627)SPR028783417 (SPR)1477-7525-6-78-e DE-627 ger DE-627 rakwb eng Gentile, Stéphanie verfasserin aut Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Gentile et al; licensee BioMed Central Ltd. 2008 Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. Stressful Life Event (dpeaa)DE-He213 Renal Transplant Recipient (dpeaa)DE-He213 General Health Perception (dpeaa)DE-He213 Cognitive Debriefing (dpeaa)DE-He213 Item Level Analysis (dpeaa)DE-He213 Jouve, Elisabeth aut Dussol, Bertrand aut Moal, Valerie aut Berland, Yvon aut Sambuc, Roland aut Enthalten in Health and quality of life outcomes London : BioMed Central, 2003 6(2008), 1 vom: 13. Okt. (DE-627)360059651 (DE-600)2098765-1 1477-7525 nnns volume:6 year:2008 number:1 day:13 month:10 https://dx.doi.org/10.1186/1477-7525-6-78 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_375 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2008 1 13 10 |
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10.1186/1477-7525-6-78 doi (DE-627)SPR028783417 (SPR)1477-7525-6-78-e DE-627 ger DE-627 rakwb eng Gentile, Stéphanie verfasserin aut Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Gentile et al; licensee BioMed Central Ltd. 2008 Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. Stressful Life Event (dpeaa)DE-He213 Renal Transplant Recipient (dpeaa)DE-He213 General Health Perception (dpeaa)DE-He213 Cognitive Debriefing (dpeaa)DE-He213 Item Level Analysis (dpeaa)DE-He213 Jouve, Elisabeth aut Dussol, Bertrand aut Moal, Valerie aut Berland, Yvon aut Sambuc, Roland aut Enthalten in Health and quality of life outcomes London : BioMed Central, 2003 6(2008), 1 vom: 13. Okt. (DE-627)360059651 (DE-600)2098765-1 1477-7525 nnns volume:6 year:2008 number:1 day:13 month:10 https://dx.doi.org/10.1186/1477-7525-6-78 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_375 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2008 1 13 10 |
allfieldsGer |
10.1186/1477-7525-6-78 doi (DE-627)SPR028783417 (SPR)1477-7525-6-78-e DE-627 ger DE-627 rakwb eng Gentile, Stéphanie verfasserin aut Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Gentile et al; licensee BioMed Central Ltd. 2008 Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. Stressful Life Event (dpeaa)DE-He213 Renal Transplant Recipient (dpeaa)DE-He213 General Health Perception (dpeaa)DE-He213 Cognitive Debriefing (dpeaa)DE-He213 Item Level Analysis (dpeaa)DE-He213 Jouve, Elisabeth aut Dussol, Bertrand aut Moal, Valerie aut Berland, Yvon aut Sambuc, Roland aut Enthalten in Health and quality of life outcomes London : BioMed Central, 2003 6(2008), 1 vom: 13. Okt. (DE-627)360059651 (DE-600)2098765-1 1477-7525 nnns volume:6 year:2008 number:1 day:13 month:10 https://dx.doi.org/10.1186/1477-7525-6-78 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_375 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2008 1 13 10 |
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10.1186/1477-7525-6-78 doi (DE-627)SPR028783417 (SPR)1477-7525-6-78-e DE-627 ger DE-627 rakwb eng Gentile, Stéphanie verfasserin aut Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Gentile et al; licensee BioMed Central Ltd. 2008 Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. Stressful Life Event (dpeaa)DE-He213 Renal Transplant Recipient (dpeaa)DE-He213 General Health Perception (dpeaa)DE-He213 Cognitive Debriefing (dpeaa)DE-He213 Item Level Analysis (dpeaa)DE-He213 Jouve, Elisabeth aut Dussol, Bertrand aut Moal, Valerie aut Berland, Yvon aut Sambuc, Roland aut Enthalten in Health and quality of life outcomes London : BioMed Central, 2003 6(2008), 1 vom: 13. Okt. (DE-627)360059651 (DE-600)2098765-1 1477-7525 nnns volume:6 year:2008 number:1 day:13 month:10 https://dx.doi.org/10.1186/1477-7525-6-78 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_375 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2008 1 13 10 |
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Gentile, Stéphanie misc Stressful Life Event misc Renal Transplant Recipient misc General Health Perception misc Cognitive Debriefing misc Item Level Analysis Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL |
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Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL Stressful Life Event (dpeaa)DE-He213 Renal Transplant Recipient (dpeaa)DE-He213 General Health Perception (dpeaa)DE-He213 Cognitive Debriefing (dpeaa)DE-He213 Item Level Analysis (dpeaa)DE-He213 |
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development and validation of a french patient-based health-related quality of life instrument in kidney transplant: the retransqol |
title_auth |
Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL |
abstract |
Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. © Gentile et al; licensee BioMed Central Ltd. 2008 |
abstractGer |
Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. © Gentile et al; licensee BioMed Central Ltd. 2008 |
abstract_unstemmed |
Background In the absence of a French health-related quality of life (QOL) instrument for renal transplant recipients (RTR), we developed a self-administered questionnaire: the ReTransQol (RTQ). Methods This questionnaire was developed using classical methodology in the following three phases over a two-year period: Item Generation phase, identifying all possible items having adverse impact on the QOL of RTR, Item Reduction phase, selecting the most pertinent items related to QOL, and Validation phase, analyzing the psychometric properties. All RTR involved in these phases were over 18 and were randomly selected from a transplant registry. Results Item generation was conducted through 24 interviews of RTR. The first version of RTQ (85 items) was sent to 225 randomized RTR, and 40 items were eliminated at the end of the item reduction phase. The second version of RTQ (45 items) was validated from 130 RTR, resulting in the RTQ final version. The factor analysis identified a structure of five factors: Physical Health (PH), Mental Health (MH), Medical Care (MC), Fear of losing the Graft (FG) and Treatment (TR). The psychometric properties of RTQ were satisfactory. Comparison between known groups from the literature confirmed the construct validity: patients without employment or living alone have lower QOL scores, and women have lower QOL scores than men. RTQ was more responsive than SF36 to detect changes in the QOL of RTR who were hospitalized secondary to their renal disease in the 4 weeks preceding their inclusion. Conclusion According to French public health priorities, RTQ appears to be a reliable and valid questionnaire. © Gentile et al; licensee BioMed Central Ltd. 2008 |
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title_short |
Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL |
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https://dx.doi.org/10.1186/1477-7525-6-78 |
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Jouve, Elisabeth Dussol, Bertrand Moal, Valerie Berland, Yvon Sambuc, Roland |
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