Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix
Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile...
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| Autor*in: |
Maheshwari, Amita [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2006 |
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| Anmerkung: |
© Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( |
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| Übergeordnetes Werk: |
Enthalten in: World journal of surgical oncology - London : Biomed Central, 2003, 4(2006), 1 vom: 01. Juli |
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| Übergeordnetes Werk: |
volume:4 ; year:2006 ; number:1 ; day:01 ; month:07 |
| Links: |
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| DOI / URN: |
10.1186/1477-7819-4-36 |
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SPR028810325 |
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| 520 | |a Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. | ||
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10.1186/1477-7819-4-36 doi (DE-627)SPR028810325 (SPR)1477-7819-4-36-e DE-627 ger DE-627 rakwb eng Maheshwari, Amita verfasserin aut Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. Vaginal Vault (dpeaa)DE-He213 Endometrial Stromal Sarcoma (dpeaa)DE-He213 Sarcomatoid Carcinoma (dpeaa)DE-He213 Sarcomatous Component (dpeaa)DE-He213 Cervical Squamous Cell Carcinoma (dpeaa)DE-He213 Gupta, Sudeep aut Shet, Tanuja aut Wuntkal, Rekha aut Tongaonkar, Hemant B aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 4(2006), 1 vom: 01. Juli (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:4 year:2006 number:1 day:01 month:07 https://dx.doi.org/10.1186/1477-7819-4-36 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2006 1 01 07 |
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10.1186/1477-7819-4-36 doi (DE-627)SPR028810325 (SPR)1477-7819-4-36-e DE-627 ger DE-627 rakwb eng Maheshwari, Amita verfasserin aut Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. Vaginal Vault (dpeaa)DE-He213 Endometrial Stromal Sarcoma (dpeaa)DE-He213 Sarcomatoid Carcinoma (dpeaa)DE-He213 Sarcomatous Component (dpeaa)DE-He213 Cervical Squamous Cell Carcinoma (dpeaa)DE-He213 Gupta, Sudeep aut Shet, Tanuja aut Wuntkal, Rekha aut Tongaonkar, Hemant B aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 4(2006), 1 vom: 01. Juli (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:4 year:2006 number:1 day:01 month:07 https://dx.doi.org/10.1186/1477-7819-4-36 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2006 1 01 07 |
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10.1186/1477-7819-4-36 doi (DE-627)SPR028810325 (SPR)1477-7819-4-36-e DE-627 ger DE-627 rakwb eng Maheshwari, Amita verfasserin aut Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. Vaginal Vault (dpeaa)DE-He213 Endometrial Stromal Sarcoma (dpeaa)DE-He213 Sarcomatoid Carcinoma (dpeaa)DE-He213 Sarcomatous Component (dpeaa)DE-He213 Cervical Squamous Cell Carcinoma (dpeaa)DE-He213 Gupta, Sudeep aut Shet, Tanuja aut Wuntkal, Rekha aut Tongaonkar, Hemant B aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 4(2006), 1 vom: 01. Juli (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:4 year:2006 number:1 day:01 month:07 https://dx.doi.org/10.1186/1477-7819-4-36 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2006 1 01 07 |
| allfieldsGer |
10.1186/1477-7819-4-36 doi (DE-627)SPR028810325 (SPR)1477-7819-4-36-e DE-627 ger DE-627 rakwb eng Maheshwari, Amita verfasserin aut Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. Vaginal Vault (dpeaa)DE-He213 Endometrial Stromal Sarcoma (dpeaa)DE-He213 Sarcomatoid Carcinoma (dpeaa)DE-He213 Sarcomatous Component (dpeaa)DE-He213 Cervical Squamous Cell Carcinoma (dpeaa)DE-He213 Gupta, Sudeep aut Shet, Tanuja aut Wuntkal, Rekha aut Tongaonkar, Hemant B aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 4(2006), 1 vom: 01. Juli (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:4 year:2006 number:1 day:01 month:07 https://dx.doi.org/10.1186/1477-7819-4-36 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2006 1 01 07 |
| allfieldsSound |
10.1186/1477-7819-4-36 doi (DE-627)SPR028810325 (SPR)1477-7819-4-36-e DE-627 ger DE-627 rakwb eng Maheshwari, Amita verfasserin aut Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. Vaginal Vault (dpeaa)DE-He213 Endometrial Stromal Sarcoma (dpeaa)DE-He213 Sarcomatoid Carcinoma (dpeaa)DE-He213 Sarcomatous Component (dpeaa)DE-He213 Cervical Squamous Cell Carcinoma (dpeaa)DE-He213 Gupta, Sudeep aut Shet, Tanuja aut Wuntkal, Rekha aut Tongaonkar, Hemant B aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 4(2006), 1 vom: 01. Juli (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:4 year:2006 number:1 day:01 month:07 https://dx.doi.org/10.1186/1477-7819-4-36 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2006 1 01 07 |
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. 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Maheshwari, Amita |
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Diagnostic dilemma in a case of malignant mixed mullerian tumor of the cervix |
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Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( |
| abstractGer |
Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( |
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Background Malignant mixed mullerian tumors (MMMT) are rare biphasic malignant neoplasm. The commonest site of their occurrence in female genital tract is body of the uterus. MMMT of the cervix is extremely rare. Case presentation We report the clinical, pathological and immunohistochemical profile and diagnostic difficulties in a case of giant MMMT of the cervix in a postmenopausal woman who presented with a large cervical mass. On microscopic examination, initially tumor appeared to be endometrial stromal sarcoma, however, immunohistochemical examination revealed the biphasic nature of the tumor. The malignant epithelial component was basaloid squamous carcinoma with homologous sarcomatous component. The patient was treated with surgery. However, she experienced vaginal vault recurrence four months after the initial treatment, which was successfully treated with pelvic radiotherapy. Conclusion Accurate diagnosis of cervical MMMT is important for appropriate treatment of the patient. © Maheshwari et al; licensee BioMed Central Ltd. 2006. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( |
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| score |
7.400629 |