A recurrent epidermoid cyst of the spleen: report of a case and literature review

Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with...
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Gespeichert in:

Autor*in:	Cianci, Pasquale [verfasserIn] Tartaglia, Nicola Altamura, Amedeo Fersini, Alberto Vovola, Fernanda Sanguedolce, Francesca Ambrosi, Antonio Neri, Vincenzo

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Splenic cysts Epidermoid cyst Laparoscopic surgery Immunohistochemistry Carbohydrate antigen 19-9

Anmerkung:	© Cianci et al. 2016

Übergeordnetes Werk:	Enthalten in: World journal of surgical oncology - London : Biomed Central, 2003, 14(2016), 1 vom: 01. Apr.
Übergeordnetes Werk:	volume:14 ; year:2016 ; number:1 ; day:01 ; month:04

Links:	Volltext

DOI / URN:	10.1186/s12957-016-0857-x

Katalog-ID:	SPR028835239

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520			\|a Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary.
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allfields	10.1186/s12957-016-0857-x doi (DE-627)SPR028835239 (SPR)s12957-016-0857-x-e DE-627 ger DE-627 rakwb eng Cianci, Pasquale verfasserin aut A recurrent epidermoid cyst of the spleen: report of a case and literature review 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Cianci et al. 2016 Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. Splenic cysts (dpeaa)DE-He213 Epidermoid cyst (dpeaa)DE-He213 Laparoscopic surgery (dpeaa)DE-He213 Immunohistochemistry (dpeaa)DE-He213 Carbohydrate antigen 19-9 (dpeaa)DE-He213 Tartaglia, Nicola aut Altamura, Amedeo aut Fersini, Alberto aut Vovola, Fernanda aut Sanguedolce, Francesca aut Ambrosi, Antonio aut Neri, Vincenzo aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 14(2016), 1 vom: 01. Apr. (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:14 year:2016 number:1 day:01 month:04 https://dx.doi.org/10.1186/s12957-016-0857-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 1 01 04
spelling	10.1186/s12957-016-0857-x doi (DE-627)SPR028835239 (SPR)s12957-016-0857-x-e DE-627 ger DE-627 rakwb eng Cianci, Pasquale verfasserin aut A recurrent epidermoid cyst of the spleen: report of a case and literature review 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Cianci et al. 2016 Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. Splenic cysts (dpeaa)DE-He213 Epidermoid cyst (dpeaa)DE-He213 Laparoscopic surgery (dpeaa)DE-He213 Immunohistochemistry (dpeaa)DE-He213 Carbohydrate antigen 19-9 (dpeaa)DE-He213 Tartaglia, Nicola aut Altamura, Amedeo aut Fersini, Alberto aut Vovola, Fernanda aut Sanguedolce, Francesca aut Ambrosi, Antonio aut Neri, Vincenzo aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 14(2016), 1 vom: 01. Apr. (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:14 year:2016 number:1 day:01 month:04 https://dx.doi.org/10.1186/s12957-016-0857-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 1 01 04
allfields_unstemmed	10.1186/s12957-016-0857-x doi (DE-627)SPR028835239 (SPR)s12957-016-0857-x-e DE-627 ger DE-627 rakwb eng Cianci, Pasquale verfasserin aut A recurrent epidermoid cyst of the spleen: report of a case and literature review 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Cianci et al. 2016 Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. Splenic cysts (dpeaa)DE-He213 Epidermoid cyst (dpeaa)DE-He213 Laparoscopic surgery (dpeaa)DE-He213 Immunohistochemistry (dpeaa)DE-He213 Carbohydrate antigen 19-9 (dpeaa)DE-He213 Tartaglia, Nicola aut Altamura, Amedeo aut Fersini, Alberto aut Vovola, Fernanda aut Sanguedolce, Francesca aut Ambrosi, Antonio aut Neri, Vincenzo aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 14(2016), 1 vom: 01. Apr. (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:14 year:2016 number:1 day:01 month:04 https://dx.doi.org/10.1186/s12957-016-0857-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 1 01 04
allfieldsGer	10.1186/s12957-016-0857-x doi (DE-627)SPR028835239 (SPR)s12957-016-0857-x-e DE-627 ger DE-627 rakwb eng Cianci, Pasquale verfasserin aut A recurrent epidermoid cyst of the spleen: report of a case and literature review 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Cianci et al. 2016 Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. Splenic cysts (dpeaa)DE-He213 Epidermoid cyst (dpeaa)DE-He213 Laparoscopic surgery (dpeaa)DE-He213 Immunohistochemistry (dpeaa)DE-He213 Carbohydrate antigen 19-9 (dpeaa)DE-He213 Tartaglia, Nicola aut Altamura, Amedeo aut Fersini, Alberto aut Vovola, Fernanda aut Sanguedolce, Francesca aut Ambrosi, Antonio aut Neri, Vincenzo aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 14(2016), 1 vom: 01. Apr. (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:14 year:2016 number:1 day:01 month:04 https://dx.doi.org/10.1186/s12957-016-0857-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 1 01 04
allfieldsSound	10.1186/s12957-016-0857-x doi (DE-627)SPR028835239 (SPR)s12957-016-0857-x-e DE-627 ger DE-627 rakwb eng Cianci, Pasquale verfasserin aut A recurrent epidermoid cyst of the spleen: report of a case and literature review 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Cianci et al. 2016 Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. Splenic cysts (dpeaa)DE-He213 Epidermoid cyst (dpeaa)DE-He213 Laparoscopic surgery (dpeaa)DE-He213 Immunohistochemistry (dpeaa)DE-He213 Carbohydrate antigen 19-9 (dpeaa)DE-He213 Tartaglia, Nicola aut Altamura, Amedeo aut Fersini, Alberto aut Vovola, Fernanda aut Sanguedolce, Francesca aut Ambrosi, Antonio aut Neri, Vincenzo aut Enthalten in World journal of surgical oncology London : Biomed Central, 2003 14(2016), 1 vom: 01. Apr. (DE-627)369082907 (DE-600)2118383-1 1477-7819 nnns volume:14 year:2016 number:1 day:01 month:04 https://dx.doi.org/10.1186/s12957-016-0857-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 1 01 04
language	English
source	Enthalten in World journal of surgical oncology 14(2016), 1 vom: 01. Apr. volume:14 year:2016 number:1 day:01 month:04
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topic_facet	Splenic cysts Epidermoid cyst Laparoscopic surgery Immunohistochemistry Carbohydrate antigen 19-9
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Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. 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author	Cianci, Pasquale
spellingShingle	Cianci, Pasquale misc Splenic cysts misc Epidermoid cyst misc Laparoscopic surgery misc Immunohistochemistry misc Carbohydrate antigen 19-9 A recurrent epidermoid cyst of the spleen: report of a case and literature review
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topic_title	A recurrent epidermoid cyst of the spleen: report of a case and literature review Splenic cysts (dpeaa)DE-He213 Epidermoid cyst (dpeaa)DE-He213 Laparoscopic surgery (dpeaa)DE-He213 Immunohistochemistry (dpeaa)DE-He213 Carbohydrate antigen 19-9 (dpeaa)DE-He213
topic	misc Splenic cysts misc Epidermoid cyst misc Laparoscopic surgery misc Immunohistochemistry misc Carbohydrate antigen 19-9
topic_unstemmed	misc Splenic cysts misc Epidermoid cyst misc Laparoscopic surgery misc Immunohistochemistry misc Carbohydrate antigen 19-9
topic_browse	misc Splenic cysts misc Epidermoid cyst misc Laparoscopic surgery misc Immunohistochemistry misc Carbohydrate antigen 19-9
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title	A recurrent epidermoid cyst of the spleen: report of a case and literature review
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title_full	A recurrent epidermoid cyst of the spleen: report of a case and literature review
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author_browse	Cianci, Pasquale Tartaglia, Nicola Altamura, Amedeo Fersini, Alberto Vovola, Fernanda Sanguedolce, Francesca Ambrosi, Antonio Neri, Vincenzo
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title_sort	recurrent epidermoid cyst of the spleen: report of a case and literature review
title_auth	A recurrent epidermoid cyst of the spleen: report of a case and literature review
abstract	Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. © Cianci et al. 2016
abstractGer	Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. © Cianci et al. 2016
abstract_unstemmed	Background Splenic cysts are rare disease. Epidermoid cysts of the spleen belong to the primary nonparasitic splenic cysts group. They are an unusual event in surgical practice. Usually, epidermoid cysts occur in children and young female. Most often, they are asymptomatic, but they may present with abdominal discomfort. Case presentation We are reporting a rare case of a 23-year-old female came to our attention with history of intermittent pain and previously undergone two times to laparoscopic decapsulation of the cyst in others institutions. During hospitalization, serum and intracystic levels of tumor marker CA19-9 increased. Enhanced CT of the abdomen showed recurrent large cyst in the upper pole of the spleen with satellite nodules. Laparotomic total splenectomy was performed. Histopathological and immunoreactive examinations were executed, and they revealed stratified squamous epithelium on the inner surface of cystic wall, which was positive for EMA, CEA, and CA19-9. The diagnosis of epidermoid cyst was confirmed. Conclusions Recently, the surgical approach is changing towards conservative treatments in order to save the spleen in young patients for immunological reasons. Sometimes, this target is not achievable. In such circumstances, like recurrent large cyst, anomalous anatomical relationship to the surrounding tissues, total splenectomy is safe and necessary. © Cianci et al. 2016
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title_short	A recurrent epidermoid cyst of the spleen: report of a case and literature review
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author2	Tartaglia, Nicola Altamura, Amedeo Fersini, Alberto Vovola, Fernanda Sanguedolce, Francesca Ambrosi, Antonio Neri, Vincenzo
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up_date	2024-07-03T22:01:00.091Z
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A recurrent epidermoid cyst of the spleen: report of a case and literature review

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