Ambient air pollution and adverse birth outcomes: a natural experiment study

Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a d...
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Autor*in:	Huang, Cheng [verfasserIn] Nichols, Catherine Liu, Yang Zhang, Yunping Liu, Xiaohong Gao, Suhong Li, Zhiwen Ren, Aiguo

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Birth Weight Preterm Birth Olympic Game Maternal Exposure Adverse Birth Outcome

Anmerkung:	© Huang et al. 2015

Übergeordnetes Werk:	Enthalten in: Population health metrics - London : BioMed Central, 2003, 13(2015), 1 vom: 18. Juli
Übergeordnetes Werk:	volume:13 ; year:2015 ; number:1 ; day:18 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s12963-015-0050-4

Katalog-ID:	SPR028898311

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520			\|a Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small.
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allfields	10.1186/s12963-015-0050-4 doi (DE-627)SPR028898311 (SPR)s12963-015-0050-4-e DE-627 ger DE-627 rakwb eng Huang, Cheng verfasserin aut Ambient air pollution and adverse birth outcomes: a natural experiment study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Huang et al. 2015 Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. Birth Weight (dpeaa)DE-He213 Preterm Birth (dpeaa)DE-He213 Olympic Game (dpeaa)DE-He213 Maternal Exposure (dpeaa)DE-He213 Adverse Birth Outcome (dpeaa)DE-He213 Nichols, Catherine aut Liu, Yang aut Zhang, Yunping aut Liu, Xiaohong aut Gao, Suhong aut Li, Zhiwen aut Ren, Aiguo aut Enthalten in Population health metrics London : BioMed Central, 2003 13(2015), 1 vom: 18. Juli (DE-627)374139911 (DE-600)2127230-X 1478-7954 nnns volume:13 year:2015 number:1 day:18 month:07 https://dx.doi.org/10.1186/s12963-015-0050-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4367 GBV_ILN_4700 AR 13 2015 1 18 07
spelling	10.1186/s12963-015-0050-4 doi (DE-627)SPR028898311 (SPR)s12963-015-0050-4-e DE-627 ger DE-627 rakwb eng Huang, Cheng verfasserin aut Ambient air pollution and adverse birth outcomes: a natural experiment study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Huang et al. 2015 Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. Birth Weight (dpeaa)DE-He213 Preterm Birth (dpeaa)DE-He213 Olympic Game (dpeaa)DE-He213 Maternal Exposure (dpeaa)DE-He213 Adverse Birth Outcome (dpeaa)DE-He213 Nichols, Catherine aut Liu, Yang aut Zhang, Yunping aut Liu, Xiaohong aut Gao, Suhong aut Li, Zhiwen aut Ren, Aiguo aut Enthalten in Population health metrics London : BioMed Central, 2003 13(2015), 1 vom: 18. Juli (DE-627)374139911 (DE-600)2127230-X 1478-7954 nnns volume:13 year:2015 number:1 day:18 month:07 https://dx.doi.org/10.1186/s12963-015-0050-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4367 GBV_ILN_4700 AR 13 2015 1 18 07
allfields_unstemmed	10.1186/s12963-015-0050-4 doi (DE-627)SPR028898311 (SPR)s12963-015-0050-4-e DE-627 ger DE-627 rakwb eng Huang, Cheng verfasserin aut Ambient air pollution and adverse birth outcomes: a natural experiment study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Huang et al. 2015 Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. Birth Weight (dpeaa)DE-He213 Preterm Birth (dpeaa)DE-He213 Olympic Game (dpeaa)DE-He213 Maternal Exposure (dpeaa)DE-He213 Adverse Birth Outcome (dpeaa)DE-He213 Nichols, Catherine aut Liu, Yang aut Zhang, Yunping aut Liu, Xiaohong aut Gao, Suhong aut Li, Zhiwen aut Ren, Aiguo aut Enthalten in Population health metrics London : BioMed Central, 2003 13(2015), 1 vom: 18. Juli (DE-627)374139911 (DE-600)2127230-X 1478-7954 nnns volume:13 year:2015 number:1 day:18 month:07 https://dx.doi.org/10.1186/s12963-015-0050-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4367 GBV_ILN_4700 AR 13 2015 1 18 07
allfieldsGer	10.1186/s12963-015-0050-4 doi (DE-627)SPR028898311 (SPR)s12963-015-0050-4-e DE-627 ger DE-627 rakwb eng Huang, Cheng verfasserin aut Ambient air pollution and adverse birth outcomes: a natural experiment study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Huang et al. 2015 Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. Birth Weight (dpeaa)DE-He213 Preterm Birth (dpeaa)DE-He213 Olympic Game (dpeaa)DE-He213 Maternal Exposure (dpeaa)DE-He213 Adverse Birth Outcome (dpeaa)DE-He213 Nichols, Catherine aut Liu, Yang aut Zhang, Yunping aut Liu, Xiaohong aut Gao, Suhong aut Li, Zhiwen aut Ren, Aiguo aut Enthalten in Population health metrics London : BioMed Central, 2003 13(2015), 1 vom: 18. Juli (DE-627)374139911 (DE-600)2127230-X 1478-7954 nnns volume:13 year:2015 number:1 day:18 month:07 https://dx.doi.org/10.1186/s12963-015-0050-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4367 GBV_ILN_4700 AR 13 2015 1 18 07
allfieldsSound	10.1186/s12963-015-0050-4 doi (DE-627)SPR028898311 (SPR)s12963-015-0050-4-e DE-627 ger DE-627 rakwb eng Huang, Cheng verfasserin aut Ambient air pollution and adverse birth outcomes: a natural experiment study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Huang et al. 2015 Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. Birth Weight (dpeaa)DE-He213 Preterm Birth (dpeaa)DE-He213 Olympic Game (dpeaa)DE-He213 Maternal Exposure (dpeaa)DE-He213 Adverse Birth Outcome (dpeaa)DE-He213 Nichols, Catherine aut Liu, Yang aut Zhang, Yunping aut Liu, Xiaohong aut Gao, Suhong aut Li, Zhiwen aut Ren, Aiguo aut Enthalten in Population health metrics London : BioMed Central, 2003 13(2015), 1 vom: 18. Juli (DE-627)374139911 (DE-600)2127230-X 1478-7954 nnns volume:13 year:2015 number:1 day:18 month:07 https://dx.doi.org/10.1186/s12963-015-0050-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4367 GBV_ILN_4700 AR 13 2015 1 18 07
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Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. 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topic_title	Ambient air pollution and adverse birth outcomes: a natural experiment study Birth Weight (dpeaa)DE-He213 Preterm Birth (dpeaa)DE-He213 Olympic Game (dpeaa)DE-He213 Maternal Exposure (dpeaa)DE-He213 Adverse Birth Outcome (dpeaa)DE-He213
topic	misc Birth Weight misc Preterm Birth misc Olympic Game misc Maternal Exposure misc Adverse Birth Outcome
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title	Ambient air pollution and adverse birth outcomes: a natural experiment study
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title_full	Ambient air pollution and adverse birth outcomes: a natural experiment study
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author_browse	Huang, Cheng Nichols, Catherine Liu, Yang Zhang, Yunping Liu, Xiaohong Gao, Suhong Li, Zhiwen Ren, Aiguo
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title_sort	ambient air pollution and adverse birth outcomes: a natural experiment study
title_auth	Ambient air pollution and adverse birth outcomes: a natural experiment study
abstract	Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. © Huang et al. 2015
abstractGer	Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. © Huang et al. 2015
abstract_unstemmed	Background Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. Conclusions Exposure to ambient air pollution during certain periods of pregnancy may decrease birth weight, but the effect size is small. © Huang et al. 2015
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title_short	Ambient air pollution and adverse birth outcomes: a natural experiment study
url	https://dx.doi.org/10.1186/s12963-015-0050-4
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author2	Nichols, Catherine Liu, Yang Zhang, Yunping Liu, Xiaohong Gao, Suhong Li, Zhiwen Ren, Aiguo
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up_date	2024-07-03T22:23:22.758Z
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Consequently, ambient concentrations of nitrogen dioxide ($ NO_{2} $) and particular matter 10 micrometers or less ($ PM_{10} $), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to $ PM_{10} $ and $ NO_{2} $ during pregnancy and adverse birth outcomes. Methods We estimated the effect of $ PM_{10} $ and $ NO_{2} $ exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center. Results Among full-term births, maternal exposure to $ NO_{2} $ in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/$ m^{3} $) in $ NO_{2} $ concentration associated with a 13.78 g (95 % confidence interval: −21.12, −6.43; p < 0.0001) reduction in birth weight. This association was maintained after adjusting for other pollutants, including carbon monoxide (CO), sulfur dioxide ($ SO_{2} $), and $ PM_{10} $. No relationship was found between the concentration of $ PM_{10} $ and low birth weight among full-term births. Neither $ PM_{10} $ nor $ NO_{2} $ concentrations predicted the risk of premature birth. 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Ambient air pollution and adverse birth outcomes: a natural experiment study

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