Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs – an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

Abstract In recent years an increasing number of publications have emphasized the growing importance of hydrogen ion dynamics in modern cancer research, from etiopathogenesis and treatment. A proton [$ H^{+} $]-related mechanism underlying the initiation and progression of the neoplastic process has...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Harguindey, Salvador [verfasserIn]

Arranz, Jose Luis

Polo Orozco, Julian David

Rauch, Cyril

Fais, Stefano

Cardone, Rosa Angela

Reshkin, Stephan J

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2013

Schlagwörter:

pH and cancer

Cancer etiopathogenesis

Proton transporters

Proton transport inhibitors

Cariporide in cancer

NHE1 and cancer

Cancer treatment

Multiple drug resistance

New therapeutic paradigm in cancer

Anmerkung:

© Harguindey et al.; licensee BioMed Central Ltd. 2013

Übergeordnetes Werk:

Enthalten in: Journal of translational medicine - London : BioMed Central, 2003, 11(2013), 1 vom: 06. Nov.

Übergeordnetes Werk:

volume:11 ; year:2013 ; number:1 ; day:06 ; month:11

Links:

Volltext

DOI / URN:

10.1186/1479-5876-11-282

Katalog-ID:

SPR028949382

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