Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study

Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited f...
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Autor*in:	Posina, Kanna [verfasserIn] McLaughlin, Jeannette Rhee, Peter Li, Laura Cheng, Joshua Schapiro, William Gulotta, Ronald J Berke, Andrew D Petrossian, George A Reichek, Nathaniel Cao, Jie J

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Left atrial function Left atrial volume Left ventricular filling pressure Cardiovascular magnetic resonance

Anmerkung:	© Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (

Übergeordnetes Werk:	Enthalten in: Journal of cardiovascular magnetic resonance - London : BioMed Central, 1999, 15(2013), 1 vom: 29. Okt.
Übergeordnetes Werk:	volume:15 ; year:2013 ; number:1 ; day:29 ; month:10

Links:	Volltext

DOI / URN:	10.1186/1532-429X-15-99

Katalog-ID:	SPR02900649X

Internformat


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100	1		\|a Posina, Kanna \|e verfasserin \|4 aut
245	1	0	\|a Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
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520			\|a Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes.
650		4	\|a Left atrial function \|7 (dpeaa)DE-He213
650		4	\|a Left atrial volume \|7 (dpeaa)DE-He213
650		4	\|a Left ventricular filling pressure \|7 (dpeaa)DE-He213
650		4	\|a Cardiovascular magnetic resonance \|7 (dpeaa)DE-He213
700	1		\|a McLaughlin, Jeannette \|4 aut
700	1		\|a Rhee, Peter \|4 aut
700	1		\|a Li, Laura \|4 aut
700	1		\|a Cheng, Joshua \|4 aut
700	1		\|a Schapiro, William \|4 aut
700	1		\|a Gulotta, Ronald J \|4 aut
700	1		\|a Berke, Andrew D \|4 aut
700	1		\|a Petrossian, George A \|4 aut
700	1		\|a Reichek, Nathaniel \|4 aut
700	1		\|a Cao, Jie J \|4 aut
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allfields	10.1186/1532-429X-15-99 doi (DE-627)SPR02900649X (SPR)1532-429X-15-99-e DE-627 ger DE-627 rakwb eng Posina, Kanna verfasserin aut Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License ( Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. Left atrial function (dpeaa)DE-He213 Left atrial volume (dpeaa)DE-He213 Left ventricular filling pressure (dpeaa)DE-He213 Cardiovascular magnetic resonance (dpeaa)DE-He213 McLaughlin, Jeannette aut Rhee, Peter aut Li, Laura aut Cheng, Joshua aut Schapiro, William aut Gulotta, Ronald J aut Berke, Andrew D aut Petrossian, George A aut Reichek, Nathaniel aut Cao, Jie J aut Enthalten in Journal of cardiovascular magnetic resonance London : BioMed Central, 1999 15(2013), 1 vom: 29. Okt. (DE-627)638411602 (DE-600)2578881-4 1532-429X nnns volume:15 year:2013 number:1 day:29 month:10 https://dx.doi.org/10.1186/1532-429X-15-99 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2013 1 29 10
spelling	10.1186/1532-429X-15-99 doi (DE-627)SPR02900649X (SPR)1532-429X-15-99-e DE-627 ger DE-627 rakwb eng Posina, Kanna verfasserin aut Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License ( Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. Left atrial function (dpeaa)DE-He213 Left atrial volume (dpeaa)DE-He213 Left ventricular filling pressure (dpeaa)DE-He213 Cardiovascular magnetic resonance (dpeaa)DE-He213 McLaughlin, Jeannette aut Rhee, Peter aut Li, Laura aut Cheng, Joshua aut Schapiro, William aut Gulotta, Ronald J aut Berke, Andrew D aut Petrossian, George A aut Reichek, Nathaniel aut Cao, Jie J aut Enthalten in Journal of cardiovascular magnetic resonance London : BioMed Central, 1999 15(2013), 1 vom: 29. Okt. (DE-627)638411602 (DE-600)2578881-4 1532-429X nnns volume:15 year:2013 number:1 day:29 month:10 https://dx.doi.org/10.1186/1532-429X-15-99 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2013 1 29 10
allfields_unstemmed	10.1186/1532-429X-15-99 doi (DE-627)SPR02900649X (SPR)1532-429X-15-99-e DE-627 ger DE-627 rakwb eng Posina, Kanna verfasserin aut Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License ( Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. Left atrial function (dpeaa)DE-He213 Left atrial volume (dpeaa)DE-He213 Left ventricular filling pressure (dpeaa)DE-He213 Cardiovascular magnetic resonance (dpeaa)DE-He213 McLaughlin, Jeannette aut Rhee, Peter aut Li, Laura aut Cheng, Joshua aut Schapiro, William aut Gulotta, Ronald J aut Berke, Andrew D aut Petrossian, George A aut Reichek, Nathaniel aut Cao, Jie J aut Enthalten in Journal of cardiovascular magnetic resonance London : BioMed Central, 1999 15(2013), 1 vom: 29. Okt. (DE-627)638411602 (DE-600)2578881-4 1532-429X nnns volume:15 year:2013 number:1 day:29 month:10 https://dx.doi.org/10.1186/1532-429X-15-99 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2013 1 29 10
allfieldsGer	10.1186/1532-429X-15-99 doi (DE-627)SPR02900649X (SPR)1532-429X-15-99-e DE-627 ger DE-627 rakwb eng Posina, Kanna verfasserin aut Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License ( Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. Left atrial function (dpeaa)DE-He213 Left atrial volume (dpeaa)DE-He213 Left ventricular filling pressure (dpeaa)DE-He213 Cardiovascular magnetic resonance (dpeaa)DE-He213 McLaughlin, Jeannette aut Rhee, Peter aut Li, Laura aut Cheng, Joshua aut Schapiro, William aut Gulotta, Ronald J aut Berke, Andrew D aut Petrossian, George A aut Reichek, Nathaniel aut Cao, Jie J aut Enthalten in Journal of cardiovascular magnetic resonance London : BioMed Central, 1999 15(2013), 1 vom: 29. Okt. (DE-627)638411602 (DE-600)2578881-4 1532-429X nnns volume:15 year:2013 number:1 day:29 month:10 https://dx.doi.org/10.1186/1532-429X-15-99 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2013 1 29 10
allfieldsSound	10.1186/1532-429X-15-99 doi (DE-627)SPR02900649X (SPR)1532-429X-15-99-e DE-627 ger DE-627 rakwb eng Posina, Kanna verfasserin aut Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License ( Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. Left atrial function (dpeaa)DE-He213 Left atrial volume (dpeaa)DE-He213 Left ventricular filling pressure (dpeaa)DE-He213 Cardiovascular magnetic resonance (dpeaa)DE-He213 McLaughlin, Jeannette aut Rhee, Peter aut Li, Laura aut Cheng, Joshua aut Schapiro, William aut Gulotta, Ronald J aut Berke, Andrew D aut Petrossian, George A aut Reichek, Nathaniel aut Cao, Jie J aut Enthalten in Journal of cardiovascular magnetic resonance London : BioMed Central, 1999 15(2013), 1 vom: 29. Okt. (DE-627)638411602 (DE-600)2578881-4 1532-429X nnns volume:15 year:2013 number:1 day:29 month:10 https://dx.doi.org/10.1186/1532-429X-15-99 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2013 1 29 10
language	English
source	Enthalten in Journal of cardiovascular magnetic resonance 15(2013), 1 vom: 29. Okt. volume:15 year:2013 number:1 day:29 month:10
sourceStr	Enthalten in Journal of cardiovascular magnetic resonance 15(2013), 1 vom: 29. Okt. volume:15 year:2013 number:1 day:29 month:10
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Left atrial function Left atrial volume Left ventricular filling pressure Cardiovascular magnetic resonance
isfreeaccess_bool	false
container_title	Journal of cardiovascular magnetic resonance
authorswithroles_txt_mv	Posina, Kanna @@aut@@ McLaughlin, Jeannette @@aut@@ Rhee, Peter @@aut@@ Li, Laura @@aut@@ Cheng, Joshua @@aut@@ Schapiro, William @@aut@@ Gulotta, Ronald J @@aut@@ Berke, Andrew D @@aut@@ Petrossian, George A @@aut@@ Reichek, Nathaniel @@aut@@ Cao, Jie J @@aut@@
publishDateDaySort_date	2013-10-29T00:00:00Z
hierarchy_top_id	638411602
id	SPR02900649X
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR02900649X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520003032.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2013 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/1532-429X-15-99</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR02900649X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)1532-429X-15-99-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Posina, Kanna</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. 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author	Posina, Kanna
spellingShingle	Posina, Kanna misc Left atrial function misc Left atrial volume misc Left ventricular filling pressure misc Cardiovascular magnetic resonance Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
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topic_title	Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study Left atrial function (dpeaa)DE-He213 Left atrial volume (dpeaa)DE-He213 Left ventricular filling pressure (dpeaa)DE-He213 Cardiovascular magnetic resonance (dpeaa)DE-He213
topic	misc Left atrial function misc Left atrial volume misc Left ventricular filling pressure misc Cardiovascular magnetic resonance
topic_unstemmed	misc Left atrial function misc Left atrial volume misc Left ventricular filling pressure misc Cardiovascular magnetic resonance
topic_browse	misc Left atrial function misc Left atrial volume misc Left ventricular filling pressure misc Cardiovascular magnetic resonance
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title	Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
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title_full	Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
author_sort	Posina, Kanna
journal	Journal of cardiovascular magnetic resonance
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author_browse	Posina, Kanna McLaughlin, Jeannette Rhee, Peter Li, Laura Cheng, Joshua Schapiro, William Gulotta, Ronald J Berke, Andrew D Petrossian, George A Reichek, Nathaniel Cao, Jie J
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author-letter	Posina, Kanna
doi_str_mv	10.1186/1532-429X-15-99
title_sort	relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
title_auth	Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
abstract	Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (
abstractGer	Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (
abstract_unstemmed	Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. Future studies should further characterize LA phasic indices in clinical outcomes. © Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (
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title_short	Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study
url	https://dx.doi.org/10.1186/1532-429X-15-99
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author2	McLaughlin, Jeannette Rhee, Peter Li, Laura Cheng, Joshua Schapiro, William Gulotta, Ronald J Berke, Andrew D Petrossian, George A Reichek, Nathaniel Cao, Jie J
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up_date	2024-07-03T23:00:41.800Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR02900649X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520003032.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2013 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/1532-429X-15-99</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR02900649X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)1532-429X-15-99-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Posina, Kanna</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Posina et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Methods Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed in cine images using biplane area and length method. Three phasic LAV was assessed at LV end systole ($ LAV_{max} $), LV end diastole ($ LAV_{min} $) and late LV diastole prior to LA contraction ($ LAV_{ac} $). LAEF was assessed as global LAEF ($ LAEF_{Total} $), passive ($ LAEF_{Passive} $) and active LAEF ($ LAEF_{Contractile} $). The relationships of phasic LAV and LAEF to LVEDP were assessed using Receiver operating characteristic comparing areas under the curves (AUC). Results The mean age of the patients was 59 years. A history of heart failure was present in 16 (39%) with NYHA functional class III or IV in 8 (20%) patients. Average LV ejection fraction was 49 ± 16% ranging from 10% to 74% and LVEDP by catheterization 14 ± 8 mmHg ranging from 4 mmHg to 32 mmHg. $ LAV_{min} $ had the strongest association with LVEDP elevation (>12 mmHg) (AUC 0.765, p = 0.002), as compared to $ LAV_{max} $ (AUC 0.677, p = 0.074) and $ LAV_{ac} $ (AUC 0.735, p = 0.008). Among three phasic LAEF assessed, $ LAEF_{Total} $ had the closest association with LVEDP elevation (AUC 0.780, p = 0.001), followed by $ LAEF_{Contractile} $ (AUC 0.698, p = 0.022) and $ LAEF_{Passive} $ (AUC 0.656, p = 0.077). Conclusions Increased $ LAV_{min} $ and decreased $ LAEF_{Total} $ have the best performance in identifying elevated LVEDP among three phasic LAV and LAEF analyzed. 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Relationship of phasic left atrial volume and emptying function to left ventricular filling pressure: a cardiovascular magnetic resonance study

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