C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells

Background Triptolide is a structurally unique diterpene triepoxide with potent antitumor activity. However,the effect and mechanism of triptolide on hepatocellular carcinoma (HCC) is not well studied. Methods Cells were treated with triptolide, and the anti-HCC activity of triptolide was evaluated...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Li, Shu-Guang [verfasserIn]

Shi, Qian-Wei

Yuan, Ling-yan

Qin, Li-ping

Wang, Yan

Miao, Yu-Qing

Chen, Zhe

Ling, Chang-Quan

Qin, Wen-xing

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2018

Schlagwörter:

Liver cancer

Triptolide

miRNA cluster

Apoptosis

Anmerkung:

© The Author(s). 2018

Übergeordnetes Werk:

Enthalten in: Journal of experimental & clinical cancer research - Berlin : Springer, 2008, 37(2018), 1 vom: 09. März

Übergeordnetes Werk:

volume:37 ; year:2018 ; number:1 ; day:09 ; month:03

Links:

Volltext

DOI / URN:

10.1186/s13046-018-0698-2

Katalog-ID:

SPR029641551

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