The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer
Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or dista...
Ausführliche Beschreibung
Autor*in: |
Soyfer, Viacheslav [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014 |
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Anmerkung: |
© Soyfer et al.; licensee BioMed Central Ltd. 2014 |
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Übergeordnetes Werk: |
Enthalten in: Radiation oncology - London : BioMed Central, 2006, 9(2014), 1 vom: 23. März |
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Übergeordnetes Werk: |
volume:9 ; year:2014 ; number:1 ; day:23 ; month:03 |
Links: |
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DOI / URN: |
10.1186/1748-717X-9-81 |
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Katalog-ID: |
SPR029672775 |
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245 | 1 | 4 | |a The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer |
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520 | |a Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. | ||
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700 | 1 | |a Inbar, Moshe |4 aut | |
700 | 1 | |a Shacham-Shmueli, Einat |4 aut | |
700 | 1 | |a Corn, Benjamin W |4 aut | |
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10.1186/1748-717X-9-81 doi (DE-627)SPR029672775 (SPR)1748-717X-9-81-e DE-627 ger DE-627 rakwb eng Soyfer, Viacheslav verfasserin aut The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Soyfer et al.; licensee BioMed Central Ltd. 2014 Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. Stomach (dpeaa)DE-He213 Radiation (dpeaa)DE-He213 Time (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Geva, Ravit aut Michelson, Michael aut Inbar, Moshe aut Shacham-Shmueli, Einat aut Corn, Benjamin W aut Enthalten in Radiation oncology London : BioMed Central, 2006 9(2014), 1 vom: 23. März (DE-627)508725739 (DE-600)2224965-5 1748-717X nnns volume:9 year:2014 number:1 day:23 month:03 https://dx.doi.org/10.1186/1748-717X-9-81 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2014 1 23 03 |
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10.1186/1748-717X-9-81 doi (DE-627)SPR029672775 (SPR)1748-717X-9-81-e DE-627 ger DE-627 rakwb eng Soyfer, Viacheslav verfasserin aut The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Soyfer et al.; licensee BioMed Central Ltd. 2014 Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. Stomach (dpeaa)DE-He213 Radiation (dpeaa)DE-He213 Time (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Geva, Ravit aut Michelson, Michael aut Inbar, Moshe aut Shacham-Shmueli, Einat aut Corn, Benjamin W aut Enthalten in Radiation oncology London : BioMed Central, 2006 9(2014), 1 vom: 23. März (DE-627)508725739 (DE-600)2224965-5 1748-717X nnns volume:9 year:2014 number:1 day:23 month:03 https://dx.doi.org/10.1186/1748-717X-9-81 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2014 1 23 03 |
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10.1186/1748-717X-9-81 doi (DE-627)SPR029672775 (SPR)1748-717X-9-81-e DE-627 ger DE-627 rakwb eng Soyfer, Viacheslav verfasserin aut The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Soyfer et al.; licensee BioMed Central Ltd. 2014 Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. Stomach (dpeaa)DE-He213 Radiation (dpeaa)DE-He213 Time (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Geva, Ravit aut Michelson, Michael aut Inbar, Moshe aut Shacham-Shmueli, Einat aut Corn, Benjamin W aut Enthalten in Radiation oncology London : BioMed Central, 2006 9(2014), 1 vom: 23. März (DE-627)508725739 (DE-600)2224965-5 1748-717X nnns volume:9 year:2014 number:1 day:23 month:03 https://dx.doi.org/10.1186/1748-717X-9-81 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2014 1 23 03 |
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10.1186/1748-717X-9-81 doi (DE-627)SPR029672775 (SPR)1748-717X-9-81-e DE-627 ger DE-627 rakwb eng Soyfer, Viacheslav verfasserin aut The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Soyfer et al.; licensee BioMed Central Ltd. 2014 Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. Stomach (dpeaa)DE-He213 Radiation (dpeaa)DE-He213 Time (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Geva, Ravit aut Michelson, Michael aut Inbar, Moshe aut Shacham-Shmueli, Einat aut Corn, Benjamin W aut Enthalten in Radiation oncology London : BioMed Central, 2006 9(2014), 1 vom: 23. März (DE-627)508725739 (DE-600)2224965-5 1748-717X nnns volume:9 year:2014 number:1 day:23 month:03 https://dx.doi.org/10.1186/1748-717X-9-81 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2014 1 23 03 |
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10.1186/1748-717X-9-81 doi (DE-627)SPR029672775 (SPR)1748-717X-9-81-e DE-627 ger DE-627 rakwb eng Soyfer, Viacheslav verfasserin aut The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Soyfer et al.; licensee BioMed Central Ltd. 2014 Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. Stomach (dpeaa)DE-He213 Radiation (dpeaa)DE-He213 Time (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Geva, Ravit aut Michelson, Michael aut Inbar, Moshe aut Shacham-Shmueli, Einat aut Corn, Benjamin W aut Enthalten in Radiation oncology London : BioMed Central, 2006 9(2014), 1 vom: 23. März (DE-627)508725739 (DE-600)2224965-5 1748-717X nnns volume:9 year:2014 number:1 day:23 month:03 https://dx.doi.org/10.1186/1748-717X-9-81 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2014 1 23 03 |
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The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer Stomach (dpeaa)DE-He213 Radiation (dpeaa)DE-He213 Time (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 |
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impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer |
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The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer |
abstract |
Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. © Soyfer et al.; licensee BioMed Central Ltd. 2014 |
abstractGer |
Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. © Soyfer et al.; licensee BioMed Central Ltd. 2014 |
abstract_unstemmed |
Objectives To study the impact of time factors on local and distant metastases in stomach cancer. Methods 67 patients with gastric cancer who received adjuvant treatment were reviewed for the time to initiation of radiotherapy, overall duration of RT and the events of first local recurrence or distant metastasis. Results The risk probability of local recurrence is increased by 10% (HR = 1.1, p = 0.0009) in association with each additional day of radiotherapy and by 3.8% (HR = 1.038, p = 0.13) per increased day of waiting time before the initiation of RT. The risk probability of distant recurrence was associated with an increase of 7.4% (HR = 1.074 p = 0.0031) with each additional day of RT time and by 2.3% (HR = 1.023, p = 0.0598) following the increase of a day of waiting time. Each day of prolongation of RT beyond 36 days was associated with an increased risk of local recurrence by 10% (OR = 1.1, p = 0.015). Prolongation of waiting time prior to initiation of irradiation retained significance in multivariate analysis. Conclusion There is an association between total treatment time and, to some extent, the time between the surgery and the initiation of radiation on local control and distant metastases. © Soyfer et al.; licensee BioMed Central Ltd. 2014 |
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The impact of overall radiotherapy treatment time and delay in initiation of radiotherapy on local control and distant metastases in gastric cancer |
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score |
7.399727 |