A phase I dose escalation study of oxaliplatin plus oral S-1 and pelvic radiation in patients with locally advanced rectal cancer (SHOGUN trial)

Background The objective of this phase I study was to determine the maximum tolerated dose (MTD) and recommended dose (RD) of preoperative chemoradiotherapy (CRT) with S-1 plus oxaliplatin in patients with locally advanced rectal cancer. Methods Patients received radiotherapy in a total dose of 50.4...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Ishihara, Soichiro [verfasserIn]

Matsusaka, Satoshi

Kondo, Keisaku

Horie, Hisanaga

Uehara, Keisuke

Oguchi, Masahiko

Murofushi, Keiko

Ueno, Masashi

Mizunuma, Nobuyuki

Shinbo, Taijyu

Kato, Daiki

Okuda, Junji

Hashiguchi, Yojiro

Nakazawa, Masanori

Sunami, Eiji

Kawai, Kazushige

Yamashita, Hideomi

Okada, Tohru

Ishikawa, Yuichi

Nakajima, Toshifusa

Watanabe, Toshiaki

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Schlagwörter:

Rectal cancer

Chemoradiotherapy

Phase I study

Oxaliplatin

S-1

Anmerkung:

© Ishihara et al.; licensee BioMed Central. 2015. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (

Übergeordnetes Werk:

Enthalten in: Radiation oncology - London : BioMed Central, 2006, 10(2015), 1 vom: 23. Jan.

Übergeordnetes Werk:

volume:10 ; year:2015 ; number:1 ; day:23 ; month:01

Links:

Volltext

DOI / URN:

10.1186/s13014-015-0333-8

Katalog-ID:

SPR029703921

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