Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors

Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned pa...
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Gespeichert in:

Autor*in:	Eddleston, Michael [verfasserIn] Dawson, Andrew Karalliedde, Lakshman Dissanayake, Wasantha Hittarage, Ariyasena Azher, Shifa Buckley, Nick A

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2004

Schlagwörter:	atropine carbamate management organophosphate pesticides

Anmerkung:	© Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (

Übergeordnetes Werk:	Enthalten in: Critical care - London : BioMed Central, 1997, 8(2004), 6 vom: 22. Sept.
Übergeordnetes Werk:	volume:8 ; year:2004 ; number:6 ; day:22 ; month:09

Links:	Volltext

DOI / URN:	10.1186/cc2953

Katalog-ID:	SPR029757886

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allfields	10.1186/cc2953 doi (DE-627)SPR029757886 (SPR)cc2953-e DE-627 ger DE-627 rakwb eng Eddleston, Michael verfasserin aut Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. atropine (dpeaa)DE-He213 carbamate (dpeaa)DE-He213 management (dpeaa)DE-He213 organophosphate (dpeaa)DE-He213 pesticides (dpeaa)DE-He213 Dawson, Andrew aut Karalliedde, Lakshman aut Dissanayake, Wasantha aut Hittarage, Ariyasena aut Azher, Shifa aut Buckley, Nick A aut Enthalten in Critical care London : BioMed Central, 1997 8(2004), 6 vom: 22. Sept. (DE-627)331258269 (DE-600)2051256-9 1364-8535 nnns volume:8 year:2004 number:6 day:22 month:09 https://dx.doi.org/10.1186/cc2953 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2004 6 22 09
spelling	10.1186/cc2953 doi (DE-627)SPR029757886 (SPR)cc2953-e DE-627 ger DE-627 rakwb eng Eddleston, Michael verfasserin aut Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. atropine (dpeaa)DE-He213 carbamate (dpeaa)DE-He213 management (dpeaa)DE-He213 organophosphate (dpeaa)DE-He213 pesticides (dpeaa)DE-He213 Dawson, Andrew aut Karalliedde, Lakshman aut Dissanayake, Wasantha aut Hittarage, Ariyasena aut Azher, Shifa aut Buckley, Nick A aut Enthalten in Critical care London : BioMed Central, 1997 8(2004), 6 vom: 22. Sept. (DE-627)331258269 (DE-600)2051256-9 1364-8535 nnns volume:8 year:2004 number:6 day:22 month:09 https://dx.doi.org/10.1186/cc2953 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2004 6 22 09
allfields_unstemmed	10.1186/cc2953 doi (DE-627)SPR029757886 (SPR)cc2953-e DE-627 ger DE-627 rakwb eng Eddleston, Michael verfasserin aut Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. atropine (dpeaa)DE-He213 carbamate (dpeaa)DE-He213 management (dpeaa)DE-He213 organophosphate (dpeaa)DE-He213 pesticides (dpeaa)DE-He213 Dawson, Andrew aut Karalliedde, Lakshman aut Dissanayake, Wasantha aut Hittarage, Ariyasena aut Azher, Shifa aut Buckley, Nick A aut Enthalten in Critical care London : BioMed Central, 1997 8(2004), 6 vom: 22. Sept. (DE-627)331258269 (DE-600)2051256-9 1364-8535 nnns volume:8 year:2004 number:6 day:22 month:09 https://dx.doi.org/10.1186/cc2953 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2004 6 22 09
allfieldsGer	10.1186/cc2953 doi (DE-627)SPR029757886 (SPR)cc2953-e DE-627 ger DE-627 rakwb eng Eddleston, Michael verfasserin aut Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. atropine (dpeaa)DE-He213 carbamate (dpeaa)DE-He213 management (dpeaa)DE-He213 organophosphate (dpeaa)DE-He213 pesticides (dpeaa)DE-He213 Dawson, Andrew aut Karalliedde, Lakshman aut Dissanayake, Wasantha aut Hittarage, Ariyasena aut Azher, Shifa aut Buckley, Nick A aut Enthalten in Critical care London : BioMed Central, 1997 8(2004), 6 vom: 22. Sept. (DE-627)331258269 (DE-600)2051256-9 1364-8535 nnns volume:8 year:2004 number:6 day:22 month:09 https://dx.doi.org/10.1186/cc2953 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2004 6 22 09
allfieldsSound	10.1186/cc2953 doi (DE-627)SPR029757886 (SPR)cc2953-e DE-627 ger DE-627 rakwb eng Eddleston, Michael verfasserin aut Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. atropine (dpeaa)DE-He213 carbamate (dpeaa)DE-He213 management (dpeaa)DE-He213 organophosphate (dpeaa)DE-He213 pesticides (dpeaa)DE-He213 Dawson, Andrew aut Karalliedde, Lakshman aut Dissanayake, Wasantha aut Hittarage, Ariyasena aut Azher, Shifa aut Buckley, Nick A aut Enthalten in Critical care London : BioMed Central, 1997 8(2004), 6 vom: 22. Sept. (DE-627)331258269 (DE-600)2051256-9 1364-8535 nnns volume:8 year:2004 number:6 day:22 month:09 https://dx.doi.org/10.1186/cc2953 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2004 6 22 09
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source	Enthalten in Critical care 8(2004), 6 vom: 22. Sept. volume:8 year:2004 number:6 day:22 month:09
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topic_facet	atropine carbamate management organophosphate pesticides
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authorswithroles_txt_mv	Eddleston, Michael @@aut@@ Dawson, Andrew @@aut@@ Karalliedde, Lakshman @@aut@@ Dissanayake, Wasantha @@aut@@ Hittarage, Ariyasena @@aut@@ Azher, Shifa @@aut@@ Buckley, Nick A @@aut@@
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title_sort	early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors
title_auth	Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors
abstract	Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
abstractGer	Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
abstract_unstemmed	Abstract Severe organophosphorus or carbamate pesticide poisoning is an important clinical problem in many countries of the world. Unfortunately, little clinical research has been performed and little evidence exists with which to determine best therapy. A cohort study of acute pesticide poisoned patients was established in Sri Lanka during 2002; so far, more than 2000 pesticide poisoned patients have been treated. A protocol for the early management of severely ill, unconscious organophosphorus/carbamate-poisoned patients was developed for use by newly qualified doctors. It concentrates on the early stabilisation of patients and the individualised administration of atropine. We present it here as a guide for junior doctors in rural parts of the developing world who see the majority of such patients and as a working model around which to base research to improve patient outcome. Improved management of pesticide poisoning will result in a reduced number of suicides globally. © Eddleston et al., licensee BioMed Central Ltd. 2004. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
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title_short	Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors
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