Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis

Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identificati...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Wicha, Max S [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2006

Schlagwörter:	Stem Cell Mammary Gland Mammary Stem Mammary Stem Cell Stem Cell Phenotype

Anmerkung:	© BioMed Central Ltd 2006

Übergeordnetes Werk:	Enthalten in: Breast cancer research - London : BioMed Central, 1999, 8(2006), 5 vom: 23. Aug.
Übergeordnetes Werk:	volume:8 ; year:2006 ; number:5 ; day:23 ; month:08

Links:	Volltext

DOI / URN:	10.1186/bcr1540

Katalog-ID:	SPR029928141

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allfields	10.1186/bcr1540 doi (DE-627)SPR029928141 (SPR)bcr1540-e DE-627 ger DE-627 rakwb eng Wicha, Max S verfasserin aut Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © BioMed Central Ltd 2006 Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. Stem Cell (dpeaa)DE-He213 Mammary Gland (dpeaa)DE-He213 Mammary Stem (dpeaa)DE-He213 Mammary Stem Cell (dpeaa)DE-He213 Stem Cell Phenotype (dpeaa)DE-He213 Enthalten in Breast cancer research London : BioMed Central, 1999 8(2006), 5 vom: 23. Aug. (DE-627)326645950 (DE-600)2041618-0 1465-542X nnns volume:8 year:2006 number:5 day:23 month:08 https://dx.doi.org/10.1186/bcr1540 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2006 5 23 08
spelling	10.1186/bcr1540 doi (DE-627)SPR029928141 (SPR)bcr1540-e DE-627 ger DE-627 rakwb eng Wicha, Max S verfasserin aut Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © BioMed Central Ltd 2006 Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. Stem Cell (dpeaa)DE-He213 Mammary Gland (dpeaa)DE-He213 Mammary Stem (dpeaa)DE-He213 Mammary Stem Cell (dpeaa)DE-He213 Stem Cell Phenotype (dpeaa)DE-He213 Enthalten in Breast cancer research London : BioMed Central, 1999 8(2006), 5 vom: 23. Aug. (DE-627)326645950 (DE-600)2041618-0 1465-542X nnns volume:8 year:2006 number:5 day:23 month:08 https://dx.doi.org/10.1186/bcr1540 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2006 5 23 08
allfields_unstemmed	10.1186/bcr1540 doi (DE-627)SPR029928141 (SPR)bcr1540-e DE-627 ger DE-627 rakwb eng Wicha, Max S verfasserin aut Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © BioMed Central Ltd 2006 Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. Stem Cell (dpeaa)DE-He213 Mammary Gland (dpeaa)DE-He213 Mammary Stem (dpeaa)DE-He213 Mammary Stem Cell (dpeaa)DE-He213 Stem Cell Phenotype (dpeaa)DE-He213 Enthalten in Breast cancer research London : BioMed Central, 1999 8(2006), 5 vom: 23. Aug. (DE-627)326645950 (DE-600)2041618-0 1465-542X nnns volume:8 year:2006 number:5 day:23 month:08 https://dx.doi.org/10.1186/bcr1540 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2006 5 23 08
allfieldsGer	10.1186/bcr1540 doi (DE-627)SPR029928141 (SPR)bcr1540-e DE-627 ger DE-627 rakwb eng Wicha, Max S verfasserin aut Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © BioMed Central Ltd 2006 Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. Stem Cell (dpeaa)DE-He213 Mammary Gland (dpeaa)DE-He213 Mammary Stem (dpeaa)DE-He213 Mammary Stem Cell (dpeaa)DE-He213 Stem Cell Phenotype (dpeaa)DE-He213 Enthalten in Breast cancer research London : BioMed Central, 1999 8(2006), 5 vom: 23. Aug. (DE-627)326645950 (DE-600)2041618-0 1465-542X nnns volume:8 year:2006 number:5 day:23 month:08 https://dx.doi.org/10.1186/bcr1540 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2006 5 23 08
allfieldsSound	10.1186/bcr1540 doi (DE-627)SPR029928141 (SPR)bcr1540-e DE-627 ger DE-627 rakwb eng Wicha, Max S verfasserin aut Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis 2006 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © BioMed Central Ltd 2006 Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. Stem Cell (dpeaa)DE-He213 Mammary Gland (dpeaa)DE-He213 Mammary Stem (dpeaa)DE-He213 Mammary Stem Cell (dpeaa)DE-He213 Stem Cell Phenotype (dpeaa)DE-He213 Enthalten in Breast cancer research London : BioMed Central, 1999 8(2006), 5 vom: 23. Aug. (DE-627)326645950 (DE-600)2041618-0 1465-542X nnns volume:8 year:2006 number:5 day:23 month:08 https://dx.doi.org/10.1186/bcr1540 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2006 5 23 08
language	English
source	Enthalten in Breast cancer research 8(2006), 5 vom: 23. Aug. volume:8 year:2006 number:5 day:23 month:08
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topic_facet	Stem Cell Mammary Gland Mammary Stem Mammary Stem Cell Stem Cell Phenotype
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author	Wicha, Max S
spellingShingle	Wicha, Max S misc Stem Cell misc Mammary Gland misc Mammary Stem misc Mammary Stem Cell misc Stem Cell Phenotype Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
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topic_title	Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis Stem Cell (dpeaa)DE-He213 Mammary Gland (dpeaa)DE-He213 Mammary Stem (dpeaa)DE-He213 Mammary Stem Cell (dpeaa)DE-He213 Stem Cell Phenotype (dpeaa)DE-He213
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title	Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
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title_full	Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
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title_sort	identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
title_auth	Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
abstract	Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. © BioMed Central Ltd 2006
abstractGer	Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. © BioMed Central Ltd 2006
abstract_unstemmed	Abstract The epithelial components of the mammary gland are thought to arise from a stem cell capable of both self-renewal and multi-lineage differentiation. Furthermore, there is increasing evidence that mammary carcinomas originate in these cells or their immediate progeny. The recent identification of murine mammary stem cells should facilitate their molecular characterization and help to elucidate their role in mammary carcinogenesis. In addition, an understanding of the biology of these cells including the pathways that regulate their self-renewal and differentiation may suggest new approaches for the prevention and treatment of breast cancer. © BioMed Central Ltd 2006
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title_short	Identification of murine mammary stem cells: implications for studies of mammary development and carcinogenesis
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