De-novo design, synthesis and evaluation of novel 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives as HIV-1 reverse transcriptase inhibitors

Background Acquired Immune Deficiency Syndrome (AIDS) is the advanced stage of infection caused by Human Immunodeficiency Virus (HIV). HIV/AIDS had a great impact on society, both as an illness and as a source of discrimination. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) are structural...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Chander, Subhash [verfasserIn]

Ashok, Penta

Singh, Anupam

Murugesan, Sankaranarayanan

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2015

Schlagwörter:

Tetrahydroisoquinoline

HIV-1 RT

Docking

NNRTI

Glide

Resistance

Anmerkung:

© Chander et al. 2015. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (

Übergeordnetes Werk:

Enthalten in: Chemistry central journal - London : BioMed Central, 2007, 9(2015), 1 vom: 09. Juni

Übergeordnetes Werk:

volume:9 ; year:2015 ; number:1 ; day:09 ; month:06

Links:

Volltext

DOI / URN:

10.1186/s13065-015-0111-6

Katalog-ID:

SPR030132401

Nicht das Richtige dabei?

Schreiben Sie uns!