Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)

Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response ar...
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Autor*in:	Favila-Ruiz, Guadalupe [verfasserIn] Jiménez-Cortés, J. Guillermo Córdoba-Aguilar, Alex Salazar-Schettino, Paz María Gutiérrez-Cabrera, Ana E. Pérez-Torres, Armando De Fuentes-Vicente, José Antonio Vences-Blanco, Mauro O. Bucio-Torres, Martha I. Flores-Villegas, A. Laura Cabrera-Bravo, Margarita

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Phenoloxidase Prophenoloxidase Anterior midgut Hemolymph

Anmerkung:	© The Author(s). 2018

Übergeordnetes Werk:	Enthalten in: Parasites & vectors - London : BioMed Central, 2008, 11(2018), 1 vom: 27. Juli
Übergeordnetes Werk:	volume:11 ; year:2018 ; number:1 ; day:27 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s13071-018-3016-0

Katalog-ID:	SPR030369991

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520			\|a Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi.
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allfields	10.1186/s13071-018-3016-0 doi (DE-627)SPR030369991 (SPR)s13071-018-3016-0-e DE-627 ger DE-627 rakwb eng Favila-Ruiz, Guadalupe verfasserin aut Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. Phenoloxidase (dpeaa)DE-He213 Prophenoloxidase (dpeaa)DE-He213 Anterior midgut (dpeaa)DE-He213 Hemolymph (dpeaa)DE-He213 Jiménez-Cortés, J. Guillermo aut Córdoba-Aguilar, Alex aut Salazar-Schettino, Paz María aut Gutiérrez-Cabrera, Ana E. aut Pérez-Torres, Armando aut De Fuentes-Vicente, José Antonio aut Vences-Blanco, Mauro O. aut Bucio-Torres, Martha I. aut Flores-Villegas, A. Laura aut Cabrera-Bravo, Margarita aut Enthalten in Parasites & vectors London : BioMed Central, 2008 11(2018), 1 vom: 27. Juli (DE-627)558690076 (DE-600)2409480-8 1756-3305 nnns volume:11 year:2018 number:1 day:27 month:07 https://dx.doi.org/10.1186/s13071-018-3016-0 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2018 1 27 07
spelling	10.1186/s13071-018-3016-0 doi (DE-627)SPR030369991 (SPR)s13071-018-3016-0-e DE-627 ger DE-627 rakwb eng Favila-Ruiz, Guadalupe verfasserin aut Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. Phenoloxidase (dpeaa)DE-He213 Prophenoloxidase (dpeaa)DE-He213 Anterior midgut (dpeaa)DE-He213 Hemolymph (dpeaa)DE-He213 Jiménez-Cortés, J. Guillermo aut Córdoba-Aguilar, Alex aut Salazar-Schettino, Paz María aut Gutiérrez-Cabrera, Ana E. aut Pérez-Torres, Armando aut De Fuentes-Vicente, José Antonio aut Vences-Blanco, Mauro O. aut Bucio-Torres, Martha I. aut Flores-Villegas, A. Laura aut Cabrera-Bravo, Margarita aut Enthalten in Parasites & vectors London : BioMed Central, 2008 11(2018), 1 vom: 27. Juli (DE-627)558690076 (DE-600)2409480-8 1756-3305 nnns volume:11 year:2018 number:1 day:27 month:07 https://dx.doi.org/10.1186/s13071-018-3016-0 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2018 1 27 07
allfields_unstemmed	10.1186/s13071-018-3016-0 doi (DE-627)SPR030369991 (SPR)s13071-018-3016-0-e DE-627 ger DE-627 rakwb eng Favila-Ruiz, Guadalupe verfasserin aut Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. Phenoloxidase (dpeaa)DE-He213 Prophenoloxidase (dpeaa)DE-He213 Anterior midgut (dpeaa)DE-He213 Hemolymph (dpeaa)DE-He213 Jiménez-Cortés, J. Guillermo aut Córdoba-Aguilar, Alex aut Salazar-Schettino, Paz María aut Gutiérrez-Cabrera, Ana E. aut Pérez-Torres, Armando aut De Fuentes-Vicente, José Antonio aut Vences-Blanco, Mauro O. aut Bucio-Torres, Martha I. aut Flores-Villegas, A. Laura aut Cabrera-Bravo, Margarita aut Enthalten in Parasites & vectors London : BioMed Central, 2008 11(2018), 1 vom: 27. Juli (DE-627)558690076 (DE-600)2409480-8 1756-3305 nnns volume:11 year:2018 number:1 day:27 month:07 https://dx.doi.org/10.1186/s13071-018-3016-0 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2018 1 27 07
allfieldsGer	10.1186/s13071-018-3016-0 doi (DE-627)SPR030369991 (SPR)s13071-018-3016-0-e DE-627 ger DE-627 rakwb eng Favila-Ruiz, Guadalupe verfasserin aut Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. Phenoloxidase (dpeaa)DE-He213 Prophenoloxidase (dpeaa)DE-He213 Anterior midgut (dpeaa)DE-He213 Hemolymph (dpeaa)DE-He213 Jiménez-Cortés, J. Guillermo aut Córdoba-Aguilar, Alex aut Salazar-Schettino, Paz María aut Gutiérrez-Cabrera, Ana E. aut Pérez-Torres, Armando aut De Fuentes-Vicente, José Antonio aut Vences-Blanco, Mauro O. aut Bucio-Torres, Martha I. aut Flores-Villegas, A. Laura aut Cabrera-Bravo, Margarita aut Enthalten in Parasites & vectors London : BioMed Central, 2008 11(2018), 1 vom: 27. Juli (DE-627)558690076 (DE-600)2409480-8 1756-3305 nnns volume:11 year:2018 number:1 day:27 month:07 https://dx.doi.org/10.1186/s13071-018-3016-0 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2018 1 27 07
allfieldsSound	10.1186/s13071-018-3016-0 doi (DE-627)SPR030369991 (SPR)s13071-018-3016-0-e DE-627 ger DE-627 rakwb eng Favila-Ruiz, Guadalupe verfasserin aut Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s). 2018 Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. Phenoloxidase (dpeaa)DE-He213 Prophenoloxidase (dpeaa)DE-He213 Anterior midgut (dpeaa)DE-He213 Hemolymph (dpeaa)DE-He213 Jiménez-Cortés, J. Guillermo aut Córdoba-Aguilar, Alex aut Salazar-Schettino, Paz María aut Gutiérrez-Cabrera, Ana E. aut Pérez-Torres, Armando aut De Fuentes-Vicente, José Antonio aut Vences-Blanco, Mauro O. aut Bucio-Torres, Martha I. aut Flores-Villegas, A. Laura aut Cabrera-Bravo, Margarita aut Enthalten in Parasites & vectors London : BioMed Central, 2008 11(2018), 1 vom: 27. Juli (DE-627)558690076 (DE-600)2409480-8 1756-3305 nnns volume:11 year:2018 number:1 day:27 month:07 https://dx.doi.org/10.1186/s13071-018-3016-0 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2018 1 27 07
language	English
source	Enthalten in Parasites & vectors 11(2018), 1 vom: 27. Juli volume:11 year:2018 number:1 day:27 month:07
sourceStr	Enthalten in Parasites & vectors 11(2018), 1 vom: 27. Juli volume:11 year:2018 number:1 day:27 month:07
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Phenoloxidase Prophenoloxidase Anterior midgut Hemolymph
isfreeaccess_bool	true
container_title	Parasites & vectors
authorswithroles_txt_mv	Favila-Ruiz, Guadalupe @@aut@@ Jiménez-Cortés, J. Guillermo @@aut@@ Córdoba-Aguilar, Alex @@aut@@ Salazar-Schettino, Paz María @@aut@@ Gutiérrez-Cabrera, Ana E. @@aut@@ Pérez-Torres, Armando @@aut@@ De Fuentes-Vicente, José Antonio @@aut@@ Vences-Blanco, Mauro O. @@aut@@ Bucio-Torres, Martha I. @@aut@@ Flores-Villegas, A. Laura @@aut@@ Cabrera-Bravo, Margarita @@aut@@
publishDateDaySort_date	2018-07-27T00:00:00Z
hierarchy_top_id	558690076
id	SPR030369991
language_de	englisch
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The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. 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author	Favila-Ruiz, Guadalupe
spellingShingle	Favila-Ruiz, Guadalupe misc Phenoloxidase misc Prophenoloxidase misc Anterior midgut misc Hemolymph Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)
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topic_title	Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae) Phenoloxidase (dpeaa)DE-He213 Prophenoloxidase (dpeaa)DE-He213 Anterior midgut (dpeaa)DE-He213 Hemolymph (dpeaa)DE-He213
topic	misc Phenoloxidase misc Prophenoloxidase misc Anterior midgut misc Hemolymph
topic_unstemmed	misc Phenoloxidase misc Prophenoloxidase misc Anterior midgut misc Hemolymph
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title	Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)
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title_full	Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)
author_sort	Favila-Ruiz, Guadalupe
journal	Parasites & vectors
journalStr	Parasites & vectors
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author_browse	Favila-Ruiz, Guadalupe Jiménez-Cortés, J. Guillermo Córdoba-Aguilar, Alex Salazar-Schettino, Paz María Gutiérrez-Cabrera, Ana E. Pérez-Torres, Armando De Fuentes-Vicente, José Antonio Vences-Blanco, Mauro O. Bucio-Torres, Martha I. Flores-Villegas, A. Laura Cabrera-Bravo, Margarita
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author-letter	Favila-Ruiz, Guadalupe
doi_str_mv	10.1186/s13071-018-3016-0
title_sort	effects of trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector meccus pallidipennis (hemiptera: reduviidae)
title_auth	Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)
abstract	Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. © The Author(s). 2018
abstractGer	Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. © The Author(s). 2018
abstract_unstemmed	Background Triatomine insects are vectors of Trypanosoma cruzi, the causal agent of Chagas disease. The insect-parasite interaction has been studied in relation to the transmission and prevalence of this disease. For most triatomines, however, several crucial aspects of the insect immune response are still unknown. For example, only for Rhodnius prolixus and Triatoma infestans has the activity of phenoloxidase (PO) and its zymogen prophenoloxidase (proPO) been reported in relation to the hemolymph and anterior midgut (AM). The aim of this study was to gain insight into the immune response to T. cruzi infection of an important triatomine in Mexico, Meccus pallidipennis. Methods Parasites were quantified in the rectal contents of infected M. pallidipennis groups. We examined some key factors in disease transmission, including the systemic (hemolymph) and local (gut) immune response. Results Parasites were present in the rectal contents at 4 days post-infection (pi) and reached their maximum density on day 7 pi. At 7 and 9 days pi mainly metacyclic trypomastigotes occurred. Compared to the control, the infected insects exhibited diminished PO activity in the hemolymph on days 9, 16 and 20 pi, and in the AM only on day 9. Additionally, infected insects displayed lower proPO activity in the hemolymph on day 1, but greater activity in the AM on day 28. Conclusions The parasite strain originating from M. pallidipennis rapidly colonized the rectum of nymphs of this triatomine and developed high numbers of metacyclic trypomastigotes. Neither the changes of concentrations of PO and proPO in the hemolymph nor in the AM correlated with the changes in the population of T. cruzi. © The Author(s). 2018
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container_issue	1
title_short	Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)
url	https://dx.doi.org/10.1186/s13071-018-3016-0
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author2	Jiménez-Cortés, J. Guillermo Córdoba-Aguilar, Alex Salazar-Schettino, Paz María Gutiérrez-Cabrera, Ana E. Pérez-Torres, Armando De Fuentes-Vicente, José Antonio Vences-Blanco, Mauro O. Bucio-Torres, Martha I. Flores-Villegas, A. Laura Cabrera-Bravo, Margarita
author2Str	Jiménez-Cortés, J. Guillermo Córdoba-Aguilar, Alex Salazar-Schettino, Paz María Gutiérrez-Cabrera, Ana E. Pérez-Torres, Armando De Fuentes-Vicente, José Antonio Vences-Blanco, Mauro O. Bucio-Torres, Martha I. Flores-Villegas, A. Laura Cabrera-Bravo, Margarita
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Effects of Trypanosoma cruzi on the phenoloxidase and prophenoloxidase activity in the vector Meccus pallidipennis (Hemiptera: Reduviidae)

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