Development of molecular assays in the diagnosis of Candida albicans infections

Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as cult...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Chen, Xu [verfasserIn] Shi, Wenna Liu, Ping Xu, Dongmei Sun, Shujuan

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Schlagwörter:	Molecular assay Diagnosis

Anmerkung:	© Springer-Verlag and the University of Milan 2010

Übergeordnetes Werk:	Enthalten in: Annals of microbiology - Berlin : Springer, 1998, 61(2010), 3 vom: 04. Dez., Seite 403-409
Übergeordnetes Werk:	volume:61 ; year:2010 ; number:3 ; day:04 ; month:12 ; pages:403-409

Links:	Volltext

DOI / URN:	10.1007/s13213-010-0169-2

Katalog-ID:	SPR030876192

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allfields	10.1007/s13213-010-0169-2 doi (DE-627)SPR030876192 (SPR)s13213-010-0169-2-e DE-627 ger DE-627 rakwb eng Chen, Xu verfasserin aut Development of molecular assays in the diagnosis of Candida albicans infections 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag and the University of Milan 2010 Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. Molecular assay (dpeaa)DE-He213 Diagnosis (dpeaa)DE-He213 Shi, Wenna aut Liu, Ping aut Xu, Dongmei aut Sun, Shujuan aut Enthalten in Annals of microbiology Berlin : Springer, 1998 61(2010), 3 vom: 04. Dez., Seite 403-409 (DE-627)385615434 (DE-600)2143009-3 1869-2044 nnns volume:61 year:2010 number:3 day:04 month:12 pages:403-409 https://dx.doi.org/10.1007/s13213-010-0169-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_63 GBV_ILN_70 GBV_ILN_95 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_187 GBV_ILN_285 GBV_ILN_370 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4313 GBV_ILN_4328 GBV_ILN_4333 AR 61 2010 3 04 12 403-409
spelling	10.1007/s13213-010-0169-2 doi (DE-627)SPR030876192 (SPR)s13213-010-0169-2-e DE-627 ger DE-627 rakwb eng Chen, Xu verfasserin aut Development of molecular assays in the diagnosis of Candida albicans infections 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag and the University of Milan 2010 Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. Molecular assay (dpeaa)DE-He213 Diagnosis (dpeaa)DE-He213 Shi, Wenna aut Liu, Ping aut Xu, Dongmei aut Sun, Shujuan aut Enthalten in Annals of microbiology Berlin : Springer, 1998 61(2010), 3 vom: 04. Dez., Seite 403-409 (DE-627)385615434 (DE-600)2143009-3 1869-2044 nnns volume:61 year:2010 number:3 day:04 month:12 pages:403-409 https://dx.doi.org/10.1007/s13213-010-0169-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_63 GBV_ILN_70 GBV_ILN_95 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_187 GBV_ILN_285 GBV_ILN_370 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4313 GBV_ILN_4328 GBV_ILN_4333 AR 61 2010 3 04 12 403-409
allfields_unstemmed	10.1007/s13213-010-0169-2 doi (DE-627)SPR030876192 (SPR)s13213-010-0169-2-e DE-627 ger DE-627 rakwb eng Chen, Xu verfasserin aut Development of molecular assays in the diagnosis of Candida albicans infections 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag and the University of Milan 2010 Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. Molecular assay (dpeaa)DE-He213 Diagnosis (dpeaa)DE-He213 Shi, Wenna aut Liu, Ping aut Xu, Dongmei aut Sun, Shujuan aut Enthalten in Annals of microbiology Berlin : Springer, 1998 61(2010), 3 vom: 04. Dez., Seite 403-409 (DE-627)385615434 (DE-600)2143009-3 1869-2044 nnns volume:61 year:2010 number:3 day:04 month:12 pages:403-409 https://dx.doi.org/10.1007/s13213-010-0169-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_63 GBV_ILN_70 GBV_ILN_95 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_187 GBV_ILN_285 GBV_ILN_370 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4313 GBV_ILN_4328 GBV_ILN_4333 AR 61 2010 3 04 12 403-409
allfieldsGer	10.1007/s13213-010-0169-2 doi (DE-627)SPR030876192 (SPR)s13213-010-0169-2-e DE-627 ger DE-627 rakwb eng Chen, Xu verfasserin aut Development of molecular assays in the diagnosis of Candida albicans infections 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag and the University of Milan 2010 Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. Molecular assay (dpeaa)DE-He213 Diagnosis (dpeaa)DE-He213 Shi, Wenna aut Liu, Ping aut Xu, Dongmei aut Sun, Shujuan aut Enthalten in Annals of microbiology Berlin : Springer, 1998 61(2010), 3 vom: 04. Dez., Seite 403-409 (DE-627)385615434 (DE-600)2143009-3 1869-2044 nnns volume:61 year:2010 number:3 day:04 month:12 pages:403-409 https://dx.doi.org/10.1007/s13213-010-0169-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_63 GBV_ILN_70 GBV_ILN_95 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_187 GBV_ILN_285 GBV_ILN_370 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4313 GBV_ILN_4328 GBV_ILN_4333 AR 61 2010 3 04 12 403-409
allfieldsSound	10.1007/s13213-010-0169-2 doi (DE-627)SPR030876192 (SPR)s13213-010-0169-2-e DE-627 ger DE-627 rakwb eng Chen, Xu verfasserin aut Development of molecular assays in the diagnosis of Candida albicans infections 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag and the University of Milan 2010 Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. Molecular assay (dpeaa)DE-He213 Diagnosis (dpeaa)DE-He213 Shi, Wenna aut Liu, Ping aut Xu, Dongmei aut Sun, Shujuan aut Enthalten in Annals of microbiology Berlin : Springer, 1998 61(2010), 3 vom: 04. Dez., Seite 403-409 (DE-627)385615434 (DE-600)2143009-3 1869-2044 nnns volume:61 year:2010 number:3 day:04 month:12 pages:403-409 https://dx.doi.org/10.1007/s13213-010-0169-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_22 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_63 GBV_ILN_70 GBV_ILN_95 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_187 GBV_ILN_285 GBV_ILN_370 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4313 GBV_ILN_4328 GBV_ILN_4333 AR 61 2010 3 04 12 403-409
language	English
source	Enthalten in Annals of microbiology 61(2010), 3 vom: 04. Dez., Seite 403-409 volume:61 year:2010 number:3 day:04 month:12 pages:403-409
sourceStr	Enthalten in Annals of microbiology 61(2010), 3 vom: 04. Dez., Seite 403-409 volume:61 year:2010 number:3 day:04 month:12 pages:403-409
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topic_facet	Molecular assay Diagnosis
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authorswithroles_txt_mv	Chen, Xu @@aut@@ Shi, Wenna @@aut@@ Liu, Ping @@aut@@ Xu, Dongmei @@aut@@ Sun, Shujuan @@aut@@
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spellingShingle	Chen, Xu misc Molecular assay misc Diagnosis Development of molecular assays in the diagnosis of Candida albicans infections
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title_sort	development of molecular assays in the diagnosis of candida albicans infections
title_auth	Development of molecular assays in the diagnosis of Candida albicans infections
abstract	Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. © Springer-Verlag and the University of Milan 2010
abstractGer	Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. © Springer-Verlag and the University of Milan 2010
abstract_unstemmed	Abstract The incidence of invasive fungal infections has increased in immunocompromised patients, with Candida albicans being the most common pathogen. Since the diagnosis of candidemia is important for the initiation of appropriate antifungal therapy, so far many diagnostic techniques, such as culture, phenotypic tests, serological tests and so on, have been developed. However, all of these methods have significant flaws that limit their usefulness in clinical practice. In this paper, we review several newly developed and modified molecular assays that have shown promise in the clinical diagnosis of Candida albicans. © Springer-Verlag and the University of Milan 2010
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title_short	Development of molecular assays in the diagnosis of Candida albicans infections
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Development of molecular assays in the diagnosis of Candida albicans infections

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