Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity

Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’...
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Autor*in:	Rodriguez, Reynaldo A. [verfasserIn] Dellimore, Kiran H. Müller, Jacobus H.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Heart valve testing Cardiac pulse duplicator Fidelity hemodynamics Prosthetic heart valves Performance assessment

Anmerkung:	© Biomedical Engineering Society 2019

Übergeordnetes Werk:	Enthalten in: Cardiovascular engineering and technology - New York, NY : Springer, 2010, 10(2019), 3 vom: 30. Apr., Seite 423-436
Übergeordnetes Werk:	volume:10 ; year:2019 ; number:3 ; day:30 ; month:04 ; pages:423-436

Links:	Volltext

DOI / URN:	10.1007/s13239-019-00416-3

Katalog-ID:	SPR03099828X

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520			\|a Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future.
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650		4	\|a hemodynamics \|7 (dpeaa)DE-He213
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700	1		\|a Dellimore, Kiran H. \|4 aut
700	1		\|a Müller, Jacobus H. \|4 aut
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allfields	10.1007/s13239-019-00416-3 doi (DE-627)SPR03099828X (SPR)s13239-019-00416-3-e DE-627 ger DE-627 rakwb eng Rodriguez, Reynaldo A. verfasserin aut Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Biomedical Engineering Society 2019 Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. Heart valve testing (dpeaa)DE-He213 Cardiac pulse duplicator (dpeaa)DE-He213 Fidelity (dpeaa)DE-He213 hemodynamics (dpeaa)DE-He213 Prosthetic heart valves (dpeaa)DE-He213 Performance assessment (dpeaa)DE-He213 Dellimore, Kiran H. aut Müller, Jacobus H. aut Enthalten in Cardiovascular engineering and technology New York, NY : Springer, 2010 10(2019), 3 vom: 30. Apr., Seite 423-436 (DE-627)620775289 (DE-600)2543111-0 1869-4098 nnns volume:10 year:2019 number:3 day:30 month:04 pages:423-436 https://dx.doi.org/10.1007/s13239-019-00416-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 10 2019 3 30 04 423-436
spelling	10.1007/s13239-019-00416-3 doi (DE-627)SPR03099828X (SPR)s13239-019-00416-3-e DE-627 ger DE-627 rakwb eng Rodriguez, Reynaldo A. verfasserin aut Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Biomedical Engineering Society 2019 Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. Heart valve testing (dpeaa)DE-He213 Cardiac pulse duplicator (dpeaa)DE-He213 Fidelity (dpeaa)DE-He213 hemodynamics (dpeaa)DE-He213 Prosthetic heart valves (dpeaa)DE-He213 Performance assessment (dpeaa)DE-He213 Dellimore, Kiran H. aut Müller, Jacobus H. aut Enthalten in Cardiovascular engineering and technology New York, NY : Springer, 2010 10(2019), 3 vom: 30. Apr., Seite 423-436 (DE-627)620775289 (DE-600)2543111-0 1869-4098 nnns volume:10 year:2019 number:3 day:30 month:04 pages:423-436 https://dx.doi.org/10.1007/s13239-019-00416-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 10 2019 3 30 04 423-436
allfields_unstemmed	10.1007/s13239-019-00416-3 doi (DE-627)SPR03099828X (SPR)s13239-019-00416-3-e DE-627 ger DE-627 rakwb eng Rodriguez, Reynaldo A. verfasserin aut Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Biomedical Engineering Society 2019 Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. Heart valve testing (dpeaa)DE-He213 Cardiac pulse duplicator (dpeaa)DE-He213 Fidelity (dpeaa)DE-He213 hemodynamics (dpeaa)DE-He213 Prosthetic heart valves (dpeaa)DE-He213 Performance assessment (dpeaa)DE-He213 Dellimore, Kiran H. aut Müller, Jacobus H. aut Enthalten in Cardiovascular engineering and technology New York, NY : Springer, 2010 10(2019), 3 vom: 30. Apr., Seite 423-436 (DE-627)620775289 (DE-600)2543111-0 1869-4098 nnns volume:10 year:2019 number:3 day:30 month:04 pages:423-436 https://dx.doi.org/10.1007/s13239-019-00416-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 10 2019 3 30 04 423-436
allfieldsGer	10.1007/s13239-019-00416-3 doi (DE-627)SPR03099828X (SPR)s13239-019-00416-3-e DE-627 ger DE-627 rakwb eng Rodriguez, Reynaldo A. verfasserin aut Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Biomedical Engineering Society 2019 Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. Heart valve testing (dpeaa)DE-He213 Cardiac pulse duplicator (dpeaa)DE-He213 Fidelity (dpeaa)DE-He213 hemodynamics (dpeaa)DE-He213 Prosthetic heart valves (dpeaa)DE-He213 Performance assessment (dpeaa)DE-He213 Dellimore, Kiran H. aut Müller, Jacobus H. aut Enthalten in Cardiovascular engineering and technology New York, NY : Springer, 2010 10(2019), 3 vom: 30. Apr., Seite 423-436 (DE-627)620775289 (DE-600)2543111-0 1869-4098 nnns volume:10 year:2019 number:3 day:30 month:04 pages:423-436 https://dx.doi.org/10.1007/s13239-019-00416-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 10 2019 3 30 04 423-436
allfieldsSound	10.1007/s13239-019-00416-3 doi (DE-627)SPR03099828X (SPR)s13239-019-00416-3-e DE-627 ger DE-627 rakwb eng Rodriguez, Reynaldo A. verfasserin aut Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Biomedical Engineering Society 2019 Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. Heart valve testing (dpeaa)DE-He213 Cardiac pulse duplicator (dpeaa)DE-He213 Fidelity (dpeaa)DE-He213 hemodynamics (dpeaa)DE-He213 Prosthetic heart valves (dpeaa)DE-He213 Performance assessment (dpeaa)DE-He213 Dellimore, Kiran H. aut Müller, Jacobus H. aut Enthalten in Cardiovascular engineering and technology New York, NY : Springer, 2010 10(2019), 3 vom: 30. Apr., Seite 423-436 (DE-627)620775289 (DE-600)2543111-0 1869-4098 nnns volume:10 year:2019 number:3 day:30 month:04 pages:423-436 https://dx.doi.org/10.1007/s13239-019-00416-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 10 2019 3 30 04 423-436
language	English
source	Enthalten in Cardiovascular engineering and technology 10(2019), 3 vom: 30. Apr., Seite 423-436 volume:10 year:2019 number:3 day:30 month:04 pages:423-436
sourceStr	Enthalten in Cardiovascular engineering and technology 10(2019), 3 vom: 30. Apr., Seite 423-436 volume:10 year:2019 number:3 day:30 month:04 pages:423-436
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Heart valve testing Cardiac pulse duplicator Fidelity hemodynamics Prosthetic heart valves Performance assessment
isfreeaccess_bool	false
container_title	Cardiovascular engineering and technology
authorswithroles_txt_mv	Rodriguez, Reynaldo A. @@aut@@ Dellimore, Kiran H. @@aut@@ Müller, Jacobus H. @@aut@@
publishDateDaySort_date	2019-04-30T00:00:00Z
hierarchy_top_id	620775289
id	SPR03099828X
language_de	englisch
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While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. 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author	Rodriguez, Reynaldo A.
spellingShingle	Rodriguez, Reynaldo A. misc Heart valve testing misc Cardiac pulse duplicator misc Fidelity misc hemodynamics misc Prosthetic heart valves misc Performance assessment Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity
authorStr	Rodriguez, Reynaldo A.
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topic_title	Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity Heart valve testing (dpeaa)DE-He213 Cardiac pulse duplicator (dpeaa)DE-He213 Fidelity (dpeaa)DE-He213 hemodynamics (dpeaa)DE-He213 Prosthetic heart valves (dpeaa)DE-He213 Performance assessment (dpeaa)DE-He213
topic	misc Heart valve testing misc Cardiac pulse duplicator misc Fidelity misc hemodynamics misc Prosthetic heart valves misc Performance assessment
topic_unstemmed	misc Heart valve testing misc Cardiac pulse duplicator misc Fidelity misc hemodynamics misc Prosthetic heart valves misc Performance assessment
topic_browse	misc Heart valve testing misc Cardiac pulse duplicator misc Fidelity misc hemodynamics misc Prosthetic heart valves misc Performance assessment
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title	Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity
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title_full	Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity
author_sort	Rodriguez, Reynaldo A.
journal	Cardiovascular engineering and technology
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container_start_page	423
author_browse	Rodriguez, Reynaldo A. Dellimore, Kiran H. Müller, Jacobus H.
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format_se	Elektronische Aufsätze
author-letter	Rodriguez, Reynaldo A.
doi_str_mv	10.1007/s13239-019-00416-3
title_sort	evaluating the performance of cardiac pulse duplicators through the concept of fidelity
title_auth	Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity
abstract	Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. © Biomedical Engineering Society 2019
abstractGer	Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. © Biomedical Engineering Society 2019
abstract_unstemmed	Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. This approach may enable standardization of the assessment of CPD performance in the future. © Biomedical Engineering Society 2019
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container_issue	3
title_short	Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity
url	https://dx.doi.org/10.1007/s13239-019-00416-3
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author2	Dellimore, Kiran H. Müller, Jacobus H.
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up_date	2024-07-03T21:23:40.621Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR03099828X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519195503.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2019 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s13239-019-00416-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR03099828X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s13239-019-00416-3-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Rodriguez, Reynaldo A.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Biomedical Engineering Society 2019</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Introduction The advanced design techniques used in modern prosthetic heart valve (PHV) development require accurate replication of the entire cardiac cycle. While cardiac pulse duplicator (CPD) design has a direct impact on the PHV test data generated, no clear guidelines exist to evaluate the CPD’s performance. In response to this, we present a method to quantitatively assess CPD performance. Materials and Methods A method to establish the fidelity of CPDs was formulated based on the pressure/time relationship and the error related to this relationship’s target. This method was applied to assess the performance of a custom-made CPD. The performance evaluation included the assessment of the motion control system and overall repeatability of pressure measurements using a St Jude Epic 21 mm aortic valve. Results The CPD’s motion control system had an average root mean square error (RMSE) beat-to-beat tracking accuracy of 0.046 ± 0.008 mm. Assessment of the pressure measurements yielded a repeatability of < 2.4 ± 0.9 mmHg RMSE beat-to-beat differential pressure. The combination of pressure and its location within a heartbeat (fidelity) was within 5.0% of the individual targets for at least 95% of heartbeats. Conclusion Fidelity can be used to objectively quantify the performance of various aspects of CPDs and to identify the cause of unexpected PHV or CPD behaviour. It also enables comparisons to be made among various CPDs in terms of overall performance. 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Evaluating the Performance of Cardiac Pulse Duplicators Through the Concept of Fidelity

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